Vacation rentals in Mission

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Top-rated vacation rentals in Mission

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious bedroom is illuminated by natural light, featuring a minimalist wooden bed with gray bedding. A large artwork hangs above the bed, while a potted plant and small reading lamp add detail. A desk and chair are positioned nearby, enhancing the workspace.
Guest suite in Mission
4.99 out of 5 average rating, 196 reviews

Large Light Filled Quiet Artist built 2BR Apt

Large, light filled, quiet, private 2 bedroom apartment/guest suite with split bathroom (toilet and sink in one room, soaking tub/shower and sink in other), kitchenette, and ceilings up to 16'. We have been working on this space for the last 2 years to get the details just right, including hand built furniture and art by local artists. Above the din of the Mission, this apartment is a unique space built in the attic of a large Edwardian house run by artists Laurel Roth Hope and Andy Diaz Hope .

Top guest favorite
A cozy living area features wood-paneled walls and beams, illuminated by natural light. A comfortable couch is positioned near large windows that showcase a city skyline view. A rustic wooden coffee table adds charm, while a small side table complements the space.
Apartment in Duboce Triangle
4.98 out of 5 average rating, 119 reviews

Peaceful Studio in the Trees

Private Studio with a beautiful view, surrounded by urban nature. The studio is cozy and cabin-like with everything you need to enjoy your visit. The neighborhood is peaceful and quiet for a city setting. Duboce Triangle is a gorgeous, central neighborhood in San Francisco and arguably one of the best! Our walking score is 98. Enjoy Victorian houses and tree-lined walks to coffee shops, parks, restaurants, fitness studios, events, work, and easy access to public transit for all the sightseeing.

Top guest favorite
A cozy living area features a gray sofa adorned with a patterned throw blanket and colorful cushions. Two round coffee tables are positioned on a textured rug. The wall displays framed records and art, while a coffee bar is set up against the opposite wall.
Guest suite in San Francisco
4.98 out of 5 average rating, 226 reviews

Urban oasis! Deck, city views, entire place

Welcome to San Francisco! Looking for the perfect place to stay while visiting the city? Look no further than this charming and contemporary studio that offers panoramic views of the city's skyline and a glimpse of the iconic GG Bridge from your private deck. Located just a short walk from Mission, you'll be able to explore the city easily. Whether you're in town for business or pleasure, this urban paradise will make you feel right at home. A bonus - easy street parking! Book your stay today!

Top guest favorite
A tranquil garden area features lush greenery, with tropical plants surrounding a private hot tub. Soft lighting highlights the space, creating a serene ambiance. A pathway leads to the entrance of the suite, ensuring privacy and easy access for guests.
Guest suite in Mission
4.98 out of 5 average rating, 268 reviews

Mission Private 1BR/BA Garden Suite Separate Entry

Luxury garden suite w/ private entrance, private bathroom, and hot tub in one of SF's hottest neighborhoods - the Mission. No shared spaces in this quiet Inner Mission one-bedroom w/ large living room, Xfinity, Apple TV, hi-speed Wi-Fi. Lots of room to spread out & relax. Strict cleaning regimen incl 30-min UVC light treatment per room, min 24-hour vacancy, sterile wipe down of all common surfaces. Please check our location on map relative to places you plan to visit in SF. Please: no smoking.

Guest favorite
A private outdoor space features a large sectional couch surrounded by lush greenery and palm trees. A central coffee table sits on stone flooring, creating an inviting area for relaxation or socializing. Soft lighting is provided by hanging bulbs above.
Guest suite in Mission
4.99 out of 5 average rating, 158 reviews

Urban Oasis in the Mission

Modern suite with separate entrance, luxe bathroom, and private outdoor space – all a short walk to the Mission’s best food, bars, and shops! Room amenities include a mini-fridge, coffee/tea makers, Bose speaker, standing desk + large monitor, 49” TV, and king bed with organic mattress. Bathroom features a large tub, walk-in shower, and high-end towels and linens. The peaceful outdoor space is a lovely setting for afternoon drinks or a bite to eat...a true urban oasis in SF’s best location!

Top guest favorite
A cozy living area features wooden walls and vibrant floral curtains. A comfortable sofa in light grey is adorned with patterned cushions. A small table sits in the center, complemented by a softly lit floor lamp. Large glass doors open to a lush garden space.
Guest suite in Mission
4.96 out of 5 average rating, 135 reviews

Stylish Garden Suite with a dash of Vintage

SO CLOSE to SO MUCH...ice cream, coffee, food, cocktails, murals, markets, music, etc. You’ll love my place because its location is in heart of the Mission. The in-law unit is cozy, comfortable, and stylish. The garden is lovely! It's great for couples, mini-sized families, solo adventurers, and business travelers. This is a very walkable neighborhood. Note: Although private, this unit is below my house and connects by a shared laundry area and hallway. See House Manual and images for details

Top guest favorite
A modern studio space showcases a comfy bed adorned with neutral-toned bedding. A small dining table is accompanied by stylish chairs. Large windows allow for ample natural light, while greenery is visible outside. A sleek couch and minimalist decor complete the welcoming atmosphere.
Guest suite in San Francisco
4.96 out of 5 average rating, 200 reviews

Modern Bernal Heights studio-Private outdoor patio

Welcome to my modern studio with private entrance, walk-in closet, bathroom, kitchenette, and peaceful outdoor space with outdoor dining set, grill, and lounge chairs. Located on a quiet street in the Bernal Heights area and a 5min walk to Bernal Hill outdoor space, 20min walk to the shops, bars/restaurants on Cortland Avenue, 10min walk from Precita Park with local cafes, grocery store, & beautiful Park. It’s HILLY Note. kitchenette is outside the unit in private closed-off space in garage

Guest favorite
A clean and modern sleeping area features a wooden headboard with two large white pillows resting on a queen-sized bed. Above, a circular woven wall decoration adds texture and warmth to the minimalist setup.
Apartment in Potrero Hill
4.85 out of 5 average rating, 129 reviews

Stylish & quiet studio apartment in Potrero Hill

*FEATURED IN SUNSET MAGAZINE* Welcome to scenic Potrero Hill! Our studio apt has a private entrance & is perfect for city visitors. It sleeps 2, in 1 brand new queen sized bed with a comfy new Nest organic mattress. Our guest studio apartment is newly renovated with brand new modern furniture, super clean and stylish bathroom, and mini kitchen. It has a hot water kettle, sink, minibar style fridge and plates & utensils. Fresh bed linen and towels on arrival and a stock of coffee & tea

Guest favorite
A charming two-story house is presented, featuring a striking grey exterior with white trim. Double garage doors are visible at the base, and a series of steps lead to a welcoming front porch. Large windows enhance natural light, and greenery adds a touch of warmth.
Guest suite in San Francisco
4.93 out of 5 average rating, 404 reviews

Live Like a Local in Sunny Bernal Heights

Located close to the Mission and Potrero Hill, our 2 bedroom (approx 1000 sq.ft.) rental is near great restaurants, unique shopping, and the newly opened Chase Center. This 2 bedroom unit is well-stocked with everything you'll need to have a relaxing and fun-filled stay in San Francisco. There's easy access getting into and out of our neighborhood and our street has ample parking. We love to host and are excited to meet new people eager to explore all that the Bay Area has to offer!

Guest favorite
A well-lit living area features a gray sofa adorned with a rust-colored pillow. A glass coffee table houses small plants and books. Wall art is displayed above. A decorative shelf and a potted plant contribute to the inviting ambiance. A door leads to the exterior.
Guest suite in Mission
4.94 out of 5 average rating, 113 reviews

Charming Mission Apartment

Newly renovated apartment built in a 130-year-old Marina-style house with a separate entrance from the main house. Two bedrooms, one bath, a fully equipped kitchen, washer, and dryer, and a large smart TV. The apartment has a perfect placement on a quiet street, but close enough to all the great restaurants, coffee shops, and nightlife of the Mission (98 walk score). I live upstairs in the same home and am available during your stay, while guests have full privacy in their own space.

Top guest favorite
A modern living area features a spacious sectional sofa with neutral upholstery, accented by plush cushions. A glass coffee table is centered on a textured rug. Natural light fills the room through a large window, with minimalist artwork adorning the wall above the sofa.
Apartment in Potrero Hill
4.99 out of 5 average rating, 620 reviews

Hilltop Hideaway Light Filled Apartment Potrero

Enjoy stunning views in this hilltop hideaway in SF's sunniest neighborhood. Marvel at the view while enjoying a cup of coffee or a glass of wine. Work remotely with fast Wi-Fi in our modern 900-square-foot in-law apartment. We live on the floor above, so you may hear the occasional creaky floor. * 55" 4K HD Smart Television (with cable) * Hi-speed wifi * King memory foam mattress * Plenty of street parking * Stunning panoramic views STR-00007250

Guest favorite
Two inviting armchairs sit facing an open entrance, creating a seamless connection to an outdoor patio. Steps lead to a well-maintained yard, lined with greenery and serene decor, providing an ideal space for relaxation and enjoyment.
Guesthouse in Mission
4.89 out of 5 average rating, 19 reviews

Lotus Studio - Secluded Mission Getaway

This newly constructed guest suite is ideally located in the heart of the Mission District. Ideal for walking to local attractions and also well served by public transit. The space is well equipped with fridge, microwave, coffee maker, hot water dispenser etc. The queen bed is comfortable and can be folded away during the day to more room. The whirlpool tub is heated and ideal for relaxation.

Popular amenities for Mission vacation rentals

When is the best time to visit Mission?

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Quick stats about vacation rentals in Mission

  • Total vacation rentals

    Explore 740 vacation rentals in Mission

  • Verified guest reviews

    Over 37,500 verified reviews to help you choose

  • Family-friendly vacation rentals

    270 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 150 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    480 properties have a dedicated workspace

  • Wi-Fi availability

    740 of Mission vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mission rentals

  • 4.8 Average rating

    Mission stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Mission's top spots, include Four Barrel Coffee, Balmy Alley, and 16th Street / Mission Bart Station