Family-friendly vacation rentals in Mission Bay

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Top-rated family-friendly rentals in Mission Bay

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
A cozy living area features wood-paneled walls and beams, illuminated by natural light. A comfortable couch is positioned near large windows that showcase a city skyline view. A rustic wooden coffee table adds charm, while a small side table complements the space.
Apartment in Duboce Triangle
4.98 out of 5 average rating, 118 reviews

Peaceful Studio in the Trees

Private Studio with a beautiful view, surrounded by urban nature. The studio is cozy and cabin-like with everything you need to enjoy your visit. The neighborhood is peaceful and quiet for a city setting. Duboce Triangle is a gorgeous, central neighborhood in San Francisco and arguably one of the best! Our walking score is 98. Enjoy Victorian houses and tree-lined walks to coffee shops, parks, restaurants, fitness studios, events, work, and easy access to public transit for all the sightseeing.

Top guest favorite
A tranquil garden area features lush greenery, with tropical plants surrounding a private hot tub. Soft lighting highlights the space, creating a serene ambiance. A pathway leads to the entrance of the suite, ensuring privacy and easy access for guests.
Guest suite in Mission
4.98 out of 5 average rating, 268 reviews

Mission Private 1BR/BA Garden Suite Separate Entry

Luxury garden suite w/ private entrance, private bathroom, and hot tub in one of SF's hottest neighborhoods - the Mission. No shared spaces in this quiet Inner Mission one-bedroom w/ large living room, Xfinity, Apple TV, hi-speed Wi-Fi. Lots of room to spread out & relax. Strict cleaning regimen incl 30-min UVC light treatment per room, min 24-hour vacancy, sterile wipe down of all common surfaces. Please check our location on map relative to places you plan to visit in SF. Please: no smoking.

Guest favorite
A fully equipped kitchenette features a blue retro-style refrigerator and a stainless-steel sink with a modern faucet. Natural light enters through two windows overlooking a shared garden, while a door provides direct access outside, enhancing the airy atmosphere of the space.
Apartment in Portola
4.91 out of 5 average rating, 234 reviews

Garden studio oasis w/ kitchenette & private entry

Cosy, comfortable, and quiet unit with direct access to a lovely garden. 10 min. from the airport, 30 min. from downtown via express bus. Well-connected, sunny neighborhood. Free street parking. Views of the bay, mature redwood trees, easy to get to attractions. Walking distance to bustling food corridor, with restaurants, cafes, grocery stores, ATMs, pharmacy, salons, library, and more. Blocks from largest park in the city with sweeping views, historic greenhouses, and unique Freeway Greenway.

Top guest favorite
A cozy living area features wooden walls and vibrant floral curtains. A comfortable sofa in light grey is adorned with patterned cushions. A small table sits in the center, complemented by a softly lit floor lamp. Large glass doors open to a lush garden space.
Guest suite in Mission
4.96 out of 5 average rating, 135 reviews

Stylish Garden Suite with a dash of Vintage

SO CLOSE to SO MUCH...ice cream, coffee, food, cocktails, murals, markets, music, etc. You’ll love my place because its location is in heart of the Mission. The in-law unit is cozy, comfortable, and stylish. The garden is lovely! It's great for couples, mini-sized families, solo adventurers, and business travelers. This is a very walkable neighborhood. Note: Although private, this unit is below my house and connects by a shared laundry area and hallway. See House Manual and images for details

Top guest favorite
A bright living area features large bay windows fitted with bamboo shades, allowing natural light to flood the space. A plush sectional sofa is complemented by a round glass table and artful decor, including framed artwork and decorative urns on pedestal shelves.
Apartment in Mission Bay
4.98 out of 5 average rating, 568 reviews

Fabulous Artist Flat in the Heart of Potrero Hill

Decorated in the eclectic bohemian spirit of San Francisco, the living space is filled with original artwork, vibrant colors and souvenirs from travel. The flat, with its easy-going creative vibe, could be the place you discover inspiration for your next project. The flat is clean, comfortable and filled with eclectic artistic touches to the delight of our guests. Please no shoes worn inside. *Note there is temporary construction in basement of the building, which can be noisy 10:30am-5pm.

Guest favorite
A spacious bedroom is featured with a large bed covered in a colorful patterned blanket. Two lamps are positioned on each side of the bed, and artwork depicting the Golden Gate Bridge adorns the walls. Natural light streams in through a window dressed with white curtains.
Home in Portola
4.91 out of 5 average rating, 537 reviews

Spacious & Clean Apartment on Traditional SF Hill

Downstairs unit/private entrance Bright downstairs unit w/master bedroom & living room or bedroom-you choose. Private entrance. Private bath. Fridge, but no kitchen. High-speed Wi-Fi, & antenna TV. Perfect for larger groups & can sleep 5. Parking is FREE in the neighborhood & the home is located in the transitioning, yet up & coming Portola neighborhood, which is 21 min. to downtown & 16 min. from the airport! Please Note: We live in upstairs unit & you can hear our footsteps at times.

Guest favorite
A clean and modern sleeping area features a wooden headboard with two large white pillows resting on a queen-sized bed. Above, a circular woven wall decoration adds texture and warmth to the minimalist setup.
Apartment in Potrero Hill
4.85 out of 5 average rating, 127 reviews

Stylish & quiet studio apartment in Potrero Hill

*FEATURED IN SUNSET MAGAZINE* Welcome to scenic Potrero Hill! Our studio apt has a private entrance & is perfect for city visitors. It sleeps 2, in 1 brand new queen sized bed with a comfy new Nest organic mattress. Our guest studio apartment is newly renovated with brand new modern furniture, super clean and stylish bathroom, and mini kitchen. It has a hot water kettle, sink, minibar style fridge and plates & utensils. Fresh bed linen and towels on arrival and a stock of coffee & tea

Guest favorite
A charming two-story house is presented, featuring a striking grey exterior with white trim. Double garage doors are visible at the base, and a series of steps lead to a welcoming front porch. Large windows enhance natural light, and greenery adds a touch of warmth.
Guest suite in San Francisco
4.93 out of 5 average rating, 404 reviews

Live Like a Local in Sunny Bernal Heights

Located close to the Mission and Potrero Hill, our 2 bedroom (approx 1000 sq.ft.) rental is near great restaurants, unique shopping, and the newly opened Chase Center. This 2 bedroom unit is well-stocked with everything you'll need to have a relaxing and fun-filled stay in San Francisco. There's easy access getting into and out of our neighborhood and our street has ample parking. We love to host and are excited to meet new people eager to explore all that the Bay Area has to offer!

Top guest favorite
A comfortable seating area features a light-colored sofa adorned with decorative cushions and a wooden coffee table. A beige armchair complements the space, while a bookcase showcases various items and framed art adds a personal touch against the soft yellow walls.
Guest suite in Bernal Heights
4.93 out of 5 average rating, 340 reviews

Audrey & Nick's Place

Audrey and Nick’s place is a comfortable, spacious studio with a private entrance, and all the comforts of home. It is located in the renovated basement of a 19th century farmhouse and is fully apportioned with a queen size bed, a large bathroom with a deep tub and access to both front and back yards. It has all the basics, and then some. It is a perfect base of operations for days and nights on the town or around the Bay and a great place to stay in and get things done.

Guest favorite
A spacious bedroom features a king-size bed dressed in a colorful floral quilt. Natural light enters through a window draped with sheer curtains. A vintage wardrobe stands against the wall, and a small television is positioned near the foot of the bed.
Guest suite in Excelsior
4.86 out of 5 average rating, 103 reviews

Hillside Getaway in Sunny Area

Entire floor with king-size bed, full bathroom with tub, kitchen, living room, laundry area, and outdoor patio. Convenient location to some of San Francisco's most vibrant neighborhoods, including: the Mission District, Bernal Heights, Noe Valley and Glen Park. Near Cow Palace. You'll love the view of Mt Davidson, Twin Peaks and Bernal Hill. Cable TV and Wi-Fi provided. Record player and in living room. My family of 3 reside above and 1 resides below the unit. STR-0006832

Top guest favorite
The studio features a cozy sleeping area with a wooden bed frame, complemented by white bedding. A light blue sofa with decorative pillows adds comfort. Natural light is welcomed through the overhead lights, casting a warm glow on the neutral walls.
Guest suite in Potrero Hill
4.93 out of 5 average rating, 337 reviews

Private Cozy Studio Flat 4U!

On Potrero Hill, Carolina St., (1.5 miles from DT SF) our street level studio flat offers a comfortable stay in a safe quiet neighborhood. 350 Sq. Ft. SEPERATE ENTRANCE, full kitchen, private patio, located on the first floor of our family home. Deluxe queen orthopedic bed + convertible futon to a SMALL single bed. 6 blocks to a great selection of cafes, deli's, shops with ample free street parking. UCSF, ZUCKERBERG GH; Bart & Caltrain. 1.5 miles Union Sq. 20 mins SFO.

Guest favorite
A well-lit living area features a spacious couch facing a large window showcasing city views. A wooden coffee table sits on a vibrant green rug, while a bookshelf displays various books. Nearby, a sleek dresser and a full-length mirror complement the room's modern aesthetic.
Guest suite in Bernal Heights
4.92 out of 5 average rating, 106 reviews

Hilltop studio w/t panoramic view, garden, parking

Welcome to our charming guest suite on top of Bernal Heights Hill with stunning views! Located in this vibrant, charming, and super safe neighborhood, this spacious suite is perfect for your SF adventure. It is a private studio space on the ground floor separate from the main house with an ensuite bathroom, a separate entrance through the garage, and exclusive access to a beautiful garden, and free parking right outside of the house.

Popular amenities for Mission Bay family-friendly rentals

Quick stats about vacation rentals that are family-friendly in Mission Bay

  • Total vacation rentals

    Explore 20 vacation rentals in Mission Bay

  • Nightly prices starting at

    Mission Bay vacation rentals start at ﺩ.ﺇ551 per night before taxes and fees

  • Verified guest reviews

    Over 250 verified reviews to help you choose

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    20 of Mission Bay vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mission Bay rentals

  • 5 Average rating

    Mission Bay stays are highly rated by guests—averaging 5 out of 5!