Family-friendly vacation rentals in Mission Bay

Find and book unique family-friendly homes on Airbnb

Quick stats about vacation rentals that are family-friendly in Mission Bay

  • Total vacation rentals

    Explore 10 vacation rentals in Mission Bay

  • Nightly prices starting at

    Mission Bay vacation rentals start at ﺩ.ﺇ 661 per night before taxes and fees

  • Verified guest reviews

    Over 260 verified reviews to help you choose

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of Mission Bay vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mission Bay rentals

  • 5 Average rating

    Mission Bay stays are highly rated by guests—averaging 5 out of 5!

Top-rated family-friendly rentals in Mission Bay

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite
Natural light fills the spacious bedroom, highlighting a large bed adorned with white linens and decorative pillows. A wooden acoustic guitar is displayed on the wall, while floor-to-ceiling windows offer expansive views of the cityscape and construction sites.
Apartment in Civic Center
4.98 out of 5 average rating, 107 reviews

15th-Floor Luxury With Views of Downtown and The Bay

See the Salesforce Tower lit up at night from the floor-to-ceiling windows of this immaculately appointed property, which comes with a large walk-in closet plus rain shower. Music lovers will appreciate the acoustic guitar and electric keyboard. Please note that this residence does have belongings in the closet. Ample room has been reserved for guests. Modern luxury apartment with amazing views, especially at night overlooking some of SF's iconic locations such as AT&T Park, the Salesforce Tower, and the San Francisco Bay. Inside the apartment, you have a full kitchen with stainless steel appliances, queen sized bed with a down comforter, a large walk-in shower with rain shower head, and living room with a big screen TV to access Netflix/Hulu or Chromecast. The entire apartment is open for guests to use, but keep in mind there will be clothes hanging in the closet and some personal items as this is my home and not a full-time airbnb. Most of the time I will still be in the city and will be available if you need anything or have any questions about the area/apartment. Step just a block to reach the famous Market Street, while within 5 minutes is Hayes Valley, filled with hip shops, cafes, and bars. A longer stroll or 5-minute MUNI ride will reach the iconic ferry building for water-borne trips to Sausalito. 5-minute walk to Bill Graham Civic Auditorium 20-minute walk, a 5-minute drive, or 12-minute MUNI to Moscone Center 10-minute MUNI to Salesforce Tower Located within one block is BART (Bay Area Rapid Transit) which is the underground train and MUNI which is comprised of an above-ground rail system and busses. You are also able to have Uber/Lyft pick up right outside the building. However, please be sure to double check with the driver that they are dropping you off on 9th street and not the back alley (Laskie). Sometimes GPS will put a pin on Laskie street instead of 9th. There are multiple parking garages around the building and one in the building that is $30 a day and subject to availability. The city, especially SoMa is very bikeable if you were to rent bikes and explore around Market street.

Guest favorite
A bright living space features a large sectional sofa adorned with orange cushions, complemented by a colorful area rug. A wooden coffee table sits in front, and a wall-mounted art piece adds a touch of elegance. Large windows provide skyline views and abundant natural light.
Loft in South of Market
4.98 out of 5 average rating, 154 reviews

Inspiring Skyline Views From a Hip Loft in SoMa

Brew coffee in a kitchen with bold wood cabinets, then curl up with a book on a cushioned bench set along floor-to-ceiling windows offering skyline views. Modern furnishings and colorful decor forge a trendy vibe within this bright loft apartment. The loft has all imported fixtures and finishes from Italy. It has Ralph Lauren deep brown carpet on the stairs and in the bedroom/office and polished concrete on the main level. There is also remote controlled blinds on the main windows and skylights. Access to the whole area described in the Summary. I can be available 24/7 at least the first and last day of their stay. Though likely at all times. The South of Market (SoMa) neighborhood has a lot of restaurants, bars and night clubs to enjoy. It is also very close to the Moscone Center. 3 1/2 blocks away from Civic Center BART/Muni Station. 20 minute walk to downtown. 4 blocks away from Moscone Center. 20 minute walk to AT&T Park SoMa is a hip neighborhood with a ton of restaurants to choose from, bars and night clubs, start-up companies around, close to the Moscone Center.

Top guest favorite
A Victorian building with a distinctive rounded corner showcases ornate architectural details. Large windows allow natural light to flood the exterior, while green trees provide a lush frame. The entrance features a welcoming staircase leading to double doors.
Guest suite in Japantown
4.95 out of 5 average rating, 314 reviews

The Blue Vic: Pac Heights/Japantown Private Suite

Beautiful & peaceful 100% private suite in vibrant walkable Pacific Heights Victorian district -500 sqft -2 blocks from Fillmore St, Pacific Heights corridor & Japantown -50+ high-end restaurants & shopping within 6 blocks -Marble bathroom with walk-in shower -Desk & high-speed internet -Breakfast bar -2 large closets -PERFECT walk score of 100 -Excellent public transit -Easy access to all of SF & beyond We aim to offer a thoughtfully designed, hotel-quality stay in a private San Francisco home.

Top guest favorite
The living area features a spacious gray sectional sofa complemented by a vibrant area rug. Sunlight filters through tall windows adorned with shutters, illuminating the room. A decorative wall sculpture and indoor plants add visual interest, while a fireplace offers a cozy focal point.
Loft in South of Market
4.99 out of 5 average rating, 406 reviews

Near Moscone Ctr, Privacy with Style the SoMa Loft

…offering its own sense of space, style, and complete privacy. The guest quarter unfolds as a full loft retreat, spanning the first floor and mezzanine. With its own private entrance, it offers total independence with no shared living spaces. The main level features a full kitchen, dining area, and living room with a warm FP, along with laundry and a powder room designed for comfort and ease. Above, the mezzanine reveals the m.bedroom with its own bath and closets, creating a quiet sanctuary.

Top guest favorite
A spacious bedroom features a warm-colored bedspread over a queen-size bed, complemented by natural light from glass doors leading to a patio. A decorative rug covers the floor, and a desk with a chair is placed near a window, accentuated by potted plants.
Home in Bernal Heights
4.92 out of 5 average rating, 202 reviews

Private Suite & Entrance. No Shared Space.

Enjoy privacy in a newly renovated San Francisco guest suite. You will have your own entrance, bedroom & bathroom complete with a desk, sofa, & mini-fridge. Think of it like a boutique hotel room but cozier! Located in the sunny North Slope of Bernal Heights. Escape the fog and enjoy nearby parks, restaurants, and markets...many within a 5-minute walk. The Mission District is conveniently within walking distance so a number of highly-rated restaurants and cafes are easily accessible.

Superhost
A clean and modern sleeping area features a wooden headboard with two large white pillows resting on a queen-sized bed. Above, a circular woven wall decoration adds texture and warmth to the minimalist setup.
Apartment in Potrero Hill
4.84 out of 5 average rating, 157 reviews

Stylish & quiet studio apartment in Potrero Hill

*FEATURED IN SUNSET MAGAZINE* Welcome to scenic Potrero Hill! Our studio apt has a private entrance & is perfect for city visitors. It sleeps 2, in 1 brand new queen sized bed with a comfy new Nest organic mattress. Our guest studio apartment is newly renovated with brand new modern furniture, super clean and stylish bathroom, and mini kitchen. It has a hot water kettle, sink, minibar style fridge and plates & utensils. Fresh bed linen and towels on arrival and a stock of coffee & tea

Top guest favorite
A cozy living area features wood-paneled walls and beams, illuminated by natural light. A comfortable couch is positioned near large windows that showcase a city skyline view. A rustic wooden coffee table adds charm, while a small side table complements the space.
Apartment in San Francisco
4.99 out of 5 average rating, 164 reviews

Peaceful Studio in the Trees

Private Studio with a beautiful view, surrounded by urban nature. The studio is cozy and cabin-like with everything you need to enjoy your visit. The neighborhood is peaceful for a city setting. Duboce Triangle is a gorgeous, central neighborhood in San Francisco and arguably one of the best! Our walking score is 98. Enjoy Victorian houses and tree-lined walks to coffee shops, parks, restaurants, fitness studios, events, work, and easy access to public transit for all the sightseeing.

Top guest favorite
A bright living area is presented, featuring a spacious sectional sofa paired with a wood coffee table. The modern kitchen is visible in the background, equipped with stainless steel appliances. Vibrant artwork adorns the walls, complementing the open dining space with a wooden table and black chairs.
Home in Potrero Hill
4.97 out of 5 average rating, 117 reviews

Lux Large 2BR, Separate Entry, New Renovation

Welcome to Potrero Hill! We are the sunniest neighborhood in the city and are perfectly located. Our home is 15 min walk to SF General Hospital, UCSF, Mission Bay, SOMA, and the Mission district. You will get an entire bottom floor of the house, fully separated from our home. Home is brand new, built in 2022. While you have total privacy, we are on site in case anything comes up. Parking is easy and we are near the freeways, making it easy to get to Silicon Valley, Marin, or Napa.

Top guest favorite
A private garden area features modern seating arrangements, including a long sectional and armchairs surrounding a fire pit. Lush greenery and flowering plants add color to the space, while a wooden fence provides privacy. The sky above is bright with scattered clouds.
Condo in Pacific Heights
4.98 out of 5 average rating, 326 reviews

Elegant Garden Suite Steps to Lafayette Park

Garden suite in Pacific Heights steps from Lafayette Park, walkable to Fillmore & Union Street dining, shops, and cafés. Private entrance, bright studio with outdoor space and a rare private garden. Ideal location for exploring San Francisco. Includes induction cooktop for light cooking. Comfortable, well-designed space with a refined residential feel. Walk score 95. Unit is part of a multi level single family home. On separate floor from Host residence. Private entrance.

Guest favorite
A bright dining area features a wooden table surrounded by black chairs. Large windows and skylights allow natural light to fill the space. Green plants are displayed, and a cozy seating nook with cushions is visible. A sliding door leads to a deck area.
Home in Potrero Hill
4.97 out of 5 average rating, 272 reviews

2br Victorian House with Breathtaking views

Amazing Victorian House on top of Potrero Hill one of the best places in San Francisco to have a magnificent view of the city. Spacious house with terrace and garden. Fast Wifi, parking for free 24/7, smart tvs with fire stick. Very close to downtown, the Mission, Castro, Ferry building, AT&T Giants, Chase Center, general hospital, UCSF, just 15 minutes from the airport. Great restaurants, wineries, parks and the historic Anchor Steam Factory in the neighborhood.

Guest favorite
A spacious living area features a comfortable cream-colored sofa with decorative pillows, a round coffee table with a tray, and a light-colored rug. A well-lit sleeping area includes a large bed with neatly arranged linens. A dining table and chairs are visible in the background.
Guest suite in Potrero Hill
4.82 out of 5 average rating, 378 reviews

Modern Suite with Private Entrance

PRIVATE SUITE WITH SEPARATE ENTRANCE. INCLUDES WIFI, FLAT SCREEN TV (WITH APPS ONLY LIKE NETFLIX, PRIME, & YOUTUBE), LIVING ROOM RUG, COFFEE TABLE, MICROWAVE, AND FRIDGE (NO KITCHEN), BATH & PRIVATE YARD. SPACIOUS WITH CONCRETE FLOORS & A LOT LIGHT. NEW: BLACKOUT BLINDS ON ALL WINDOWS. STREET PARKING IS FREE FOR 4 HRS FROM 8-6PM MON-FRI AND FREE ALL DAY SAT AND SUN. HOUSE IS 1 BLOCK FROM SHOPS / RESTAURANTS. 2 PEOPLE MAX. NO PETS DUE TO ALLERGIES 000035STR

Top guest favorite
A bright corner of the room is enhanced by large windows that open to a balcony. A mural of a woman’s face is mounted on the wall above a large potted plant. Natural light highlights textured rugs and organic shapes of seating elements.
Home in San Francisco
4.95 out of 5 average rating, 466 reviews

Guest Perch · Dolores Park/Castro/Noe · Hot Tub

· Superfast Gigabit WiFi ‧ Host Full-Service Departure Cleaning ‧ Resplendent in warmth, light, verdant plants, objets d'art, and white oak finishes, the Guest Perch is a tranquil one-bedroom and full bath reprieve after an adventurous day in San Francisco. Stroll to Noe Valley, Castro, and Valencia neighborhoods. Easy access to MUNI, BART, Uber/Lyft, car rental, and bike share transportation options.

Popular amenities for Mission Bay family-friendly rentals