
Vacation rentals in Mira Mesa
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Top-rated vacation rentals in Mira Mesa
Guests agree: these stays are highly rated for location, cleanliness, and more.

2 Masters, Newly Renovated New Furnishings 4BR 3BA
The perfect blend of comfort and convenience for groups, families, and business travelers. Features 2 private masters, 2 guest bedrooms, and 3 full bathrooms. Open-concept layout connects 2 living rooms, dining area, and a fully equipped kitchen. Enjoy BBQ grill, Blackstone flat-top, outdoor dining, and a fire pit with relaxing seating. Professionally cleaned and stocked with home & travel essentials, this well designed space promises to exceed your expectations and have you feel right at home.

East Watch- a private getaway
East Watch is a 740 sq ft, 1 bedroom private retreat that provides the comforts and amenities of home with the style of a high-end hotel. All 5 to 15 min from shopping, downtown, and the beach. It's a short walk from Mt. Helix Park which offers a 360* view, weekday yoga, and stunning sunrises and sunsets. We have EV high speed car charging, a full kitchen with all appliances, workspace with dedicated fast WIFI, a spa shower, and super comfortable beds and pillows. Stay and let us charm you!

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV
Welcome to your personal resort! This is your private Guest House with a salt & heated pool + hot tub. Located in a very quiet & safe neighborhood in beautiful San Diego. Drive 15 minutes to the beach, downtown, La Jolla, Zoo, stadiums, Sea World, Convention Center + more. Hike next door at Cowell Mountain or Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo, top quality finishes & furniture. Everything you need for memorable vacation! No smoking or vaping on the property.

Explore San Diego from This Pet-Friendly Retreat
Welcome to our cozy Mira Mesa guesthouse in San Diego! This private 600 sq ft suite is perfect for families, friends, and pet-friendly stays. Enjoy a brand-new sofa bed (Sept 13, 2025) plus recent updates including a side bed, added storage, new wall décor, and curtains (Mar 22, 2026). The space also features a bright workspace with fast WiFi—ideal for remote work. Conveniently located near Freeway 15, you’re just 15–20 minutes from beaches, downtown, and top San Diego attractions.

Stunning Private Entrance 2bd/1ba Suite
Located in the heart of San Diego, guests are a short drive or bus ride to all the local hotspots. Shopping and restaurants are within walking distance. The space itself is large, exquisitely decorated, has a dedicated driveway parking space and its own private entrance in the front of the house. Also available are the washer/dryer for laundry, beach equipment, electric bikes (with signed waiver), cribs/toys/etc. for children. Short drive to SeaWorld, Zoo, Safari Park and beaches.

Contemporary Family-Friendly Home in SD with EV&AC
Welcome to San Diego, the city of sun and fun. This newly-renovated, spacious home has 3 beds and 2 baths with central AC, and is conveniently located in the center of San Diego with easy access to freeways 5, 805 and 15. It's close to many attractions -Legoland, Sea World, San Diego Zoo, Balboa Park, and beautiful beaches. The neighborhood has a variety of restaurants, cafes, movie theater, shopping center, and grocery stores. Just a few minutes from Sorrento Valley and UCSD.

Modern Kitchen Zen Backyard Putting Green with AC
Our beautiful home is located in the heart of San Diego. From the living room front door you'll see through to the kitchen, family room, and straight into the wide backyard with a putting green. Set up perfectly for family gatherings. Kitchen comes fully equipped. - Thermador stove, down vent hood, microwave, oven, and wide island Backyard perfect for a gathering: Safe and clean for the kids to run around. Has putting green, fire pit, and multiple lounge areas.

Gated Detached Large House Convenient/Quiet
The spacious detached casita/guest house comes with private entrance and a backyard. It has a large bedroom, walk-in closet, full bathroom, living dinning, and kitchen. The kitchen has new sink, stove/oven, refrigerators, essential cookware, utensils, and tableware. The house has a queen size bed that can sleep two adults, a sofa sleeper bed and a queen size air mattress for additional guests. Guest may use the new LG washer/dryer combo unit.

Luxury 4BR, 6 beds Smart Home in San Diego
Modern, fully upgraded 4BR/2BA home in central Mira Mesa. Prime location close to UCSD, La Jolla beaches, shopping, restaurants, and major freeways. Enjoy a stylish new kitchen, beautiful décor, spacious living room with a 75" TV, and a brand-new back patio plus a lovely front yard. Washer and dryer provided for your convenience. Perfect for families, groups, and business travelers looking for a comfortable, convenient home base in San Diego.

Charming Family 3BR w/ Game Room
Experience San Diego living in this welcoming 3-bed, 2-bath Mira Mesa home. Perfect for families with a fun game room for entertainment and a spacious backyard featuring covered patio seating and grill for outdoor dining. Minutes from scenic hiking trails, family-friendly parks, and beautiful beaches. Easy access to diverse local restaurants. Your ideal Southern California base with space for both lively gatherings and relaxing downtime.

Open Concept modern ranch w/ bounce house included
Come and relax at our California ranch style family friendly home which is a 1 story (no stairs) 3 bedroom 2 bath home in Sunny San Diego.. This open concept home has two living rooms and a backyard patio to grill and lots of grass for the kiddos to run around in. This house is centrally located in San Diego and a quick drive to the beach, the San Diego Zoo, local hospitals, Petco Park for padres, Legoland, and downtown San Diego.

STUDIO 56
Entire Private Studio Suite. The entire suite is brand new and updated with 1 queen bed, 1 double bed, and 1 full bath. Quiet midtown of Mira Mesa central drive in San Diego. Studio fully equipped with 2 beds, a leather sofa, working desk, kitchenette meant for light food warm, full size refrigerator, single sink meant for light cup and dish wash All shops, restaurants, a cinema within minus drive about 2 miles away.
Popular amenities for Mira Mesa vacation rentals
Other great vacation rentals in Mira Mesa

A Private Hideout

Designer Modern Luxury• Backyard Oasis •Sleeps 9

5-BR, 3-Bath, Garage, Yard, King Bed in Mira Mesa

Quiet, private bedroom/bathroom

Cozy Room w/Use of Kitchen。Washer 。WiFi。AC。smartTV

Quiet family home in Scripps.

Modern Suite with Private Entrance

Cielo Casita
Quick stats about vacation rentals in Mira Mesa

Total vacation rentals
Explore 290 vacation rentals in Mira Mesa

Nightly prices starting at
Mira Mesa vacation rentals start at ﺩ.ﺇ 73 per night before taxes and fees

Verified guest reviews
Over 12,420 verified reviews to help you choose

Family-friendly vacation rentals
120 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Vacation rentals with a pool
70 properties feature pools

Rentals with dedicated workspaces
190 properties have a dedicated workspace

Wi-Fi availability
290 of Mira Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mira Mesa rentals

4.8 Average rating
Mira Mesa stays are highly rated by guests—averaging 4.8 out of 5!
Destinations to explore
- Family-friendly rentals Mira Mesa
- House rentals Mira Mesa
- Rentals with a hot tub Mira Mesa
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- Rentals with a washer and dryer Mira Mesa
- Fitness-friendly rentals Mira Mesa
- Rentals with pools Mira Mesa
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- Rentals with a patio Mira Mesa
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- Private suite rentals Mira Mesa
- Pet-friendly rentals Mira Mesa
- Rentals with a fireplace Mira Mesa
- Rosarito Beach
- San Diego Convention Center E Ent
- SeaWorld San Diego
- Petco Park
- University of California-San Diego
- Oceanside City Beach
- San Diego Zoo Safari Park
- Ocean Front Walk
- Pacific Beach
- Coronado Beach
- Torrey Pines State Beach
- San Diego Zoo
- Tijuana Beach
- Balboa Park
- Pechanga Resort Casino
- San Diego State University
- San Clemente State Beach
- Mission Beach
- LEGOLAND California
- Moonlight State Beach
- Liberty Station
- Oceanside Harbor
- San Onofre Beach
- Sesame Place San Diego





