
Vacation rentals in Mira Mesa
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Top-rated vacation rentals in Mira Mesa
Guests agree: these stays are highly rated for location, cleanliness, and more.

2 Masters, Newly Renovated New Furnishings 4BR 3BA
The perfect blend of comfort and convenience for groups, families, and business travelers. Features 2 private masters, 2 guest bedrooms, and 3 full bathrooms. Open-concept layout connects 2 living rooms, dining area, and a fully equipped kitchen. Enjoy BBQ grill, Blackstone flat-top, outdoor dining, and a fire pit with relaxing seating. Professionally cleaned and stocked with home & travel essentials, this well designed space promises to exceed your expectations and have you feel right at home.

Casa Grotto, Romantic Stone Cottage w/ Ocean Views
Perched 800ft above sea level with panoramic ocean views from La Jolla to Catalina Island, Casa Grotto is a unique stone studio carved into the ocean view hillside of Lake San Marcos . Built in the 80's using stone from the mountain, the space was updated in 2025 with modern touches—featuring a rock shower, full kitchen, AC, and gym. Just 20 minutes from the beach, it’s a dreamy escape for surfers, hikers, and couples looking for a romantic getaway. No pets—our two friendly boxers live on-site

Perfect Home Base for Family Adventures
Welcome to our cozy Mira Mesa guesthouse in San Diego! This private 600 sq ft suite is perfect for families, friends, and pet-friendly stays. Enjoy a brand-new sofa bed (Sept 13, 2025) plus recent updates including a side bed, added storage, new wall décor, and curtains (Mar 22, 2026). The space also features a bright workspace with fast WiFi—ideal for remote work. Conveniently located near Freeway 15, you’re just 15–20 minutes from beaches, downtown, and top San Diego attractions.

Stunning Private Entrance 2bd/1ba Suite
Located in the heart of San Diego, guests are a short drive or bus ride to all the local hotspots. Shopping and restaurants are within walking distance. The space itself is large, exquisitely decorated, has a dedicated driveway parking space and its own private entrance in the front of the house. Also available are the washer/dryer for laundry, beach equipment, electric bikes (with signed waiver), cribs/toys/etc. for children. Short drive to SeaWorld, Zoo, Safari Park and beaches.

Contemporary Family-Friendly Home in SD with EV&AC
Welcome to San Diego, the city of sun and fun. This newly-renovated, spacious home has 3 beds and 2 baths with central AC, and is conveniently located in the center of San Diego with easy access to freeways 5, 805 and 15. It's close to many attractions -Legoland, Sea World, San Diego Zoo, Balboa Park, and beautiful beaches. The neighborhood has a variety of restaurants, cafes, movie theater, shopping center, and grocery stores. Just a few minutes from Sorrento Valley and UCSD.

Modern Kitchen Zen Backyard Putting Green with AC
Our beautiful home is located in the heart of San Diego. From the living room front door you'll see through to the kitchen, family room, and straight into the wide backyard with a putting green. Set up perfectly for family gatherings. Kitchen comes fully equipped. - Thermador stove, down vent hood, microwave, oven, and wide island Backyard perfect for a gathering: Safe and clean for the kids to run around. Has putting green, fire pit, and multiple lounge areas.

Gated Detached Large House Convenient/Quiet
The spacious detached casita/guest house comes with private entrance and a backyard. It has a large bedroom, walk-in closet, full bathroom, living dinning, and kitchen. The kitchen has new sink, stove/oven, refrigerators, essential cookware, utensils, and tableware. The house has a queen size bed that can sleep two adults, a sofa sleeper bed and a queen size air mattress for additional guests. Guest may use the new LG washer/dryer combo unit.

Charming Family 3BR w/ Game Room
Experience San Diego living in this welcoming 3-bed, 2-bath Mira Mesa home. Perfect for families with a fun game room for entertainment and a spacious backyard featuring covered patio seating and grill for outdoor dining. Minutes from scenic hiking trails, family-friendly parks, and beautiful beaches. Easy access to diverse local restaurants. Your ideal Southern California base with space for both lively gatherings and relaxing downtime.

Open Concept modern ranch w/ bounce house included
Come and relax at our California ranch style family friendly home which is a 1 story (no stairs) 3 bedroom 2 bath home in Sunny San Diego.. This open concept home has two living rooms and a backyard patio to grill and lots of grass for the kiddos to run around in. This house is centrally located in San Diego and a quick drive to the beach, the San Diego Zoo, local hospitals, Petco Park for padres, Legoland, and downtown San Diego.

Aesthetic Plant Home in MiraMesa
Our home is decorated with some modern, and French inspired fixtures along with many living plants ,please don’t touch but admire 😊 2 story home. 2 driveway parking (no garage use) 6 bedrooms, 5 beds are queens and 1 is a double 3 full bathrooms Tesla only fast charger Closest beaches La Jolla shores & Torrey Pines 20 mins away 25-30 mins to most SD attractions such Seaworld, SD Zoo, legoland, airport & downtown.

Sunset House
Welcome to Sunset Casa, perfect for families, friends, or couples. Enjoy a bright living area, fully equipped kitchen, and thoughtful touches that make you feel at home. Sip coffee on the patio or unwind after exploring San Diego’s beaches, parks, and vibrant neighborhoods. Located in a quiet area with easy access to downtown, the airport, and local attractions, Sunset Casa is the ideal base for your stay.

Charming & Spotless Studio with Own Entry
Entire Private Studio Suite. Brand new updated entire suite with 1 Queen Bed & 1 Full bathroom. Ideal for couples, solo adventurers, and business travelers. Just minutes from central of shopping and food like Asian restaurants, markets as well as 24h stores, Edward Cinema, etc... Less than 20 mins to Balboa Park, La Jolla Shores Park, Solana Beach, Moonlight Beach, San Diego Zoo, San Diego Sea World.
Popular amenities for Mira Mesa vacation rentals
Other great vacation rentals in Mira Mesa

A Romantic Family Retreat Home - Game room-Hot tub

Stylish Vacay Home Next to La Jolla UTC Restaurant

Welcome to Casa Cortina!

Designer Modern Luxury• Backyard Oasis •Sleeps 9

Mira Mesa Gem | Quiet 4BR Home Near Everything

Traveler's Dream New Modern Farmhouse Getaway

Beautiful 3Bedroom Home in the Heart of Mira Mesa

Bright Private Suite • Kitchen+AC+WD/Patio+Parking
Quick stats about vacation rentals in Mira Mesa

Total vacation rentals
Explore 290 vacation rentals in Mira Mesa

Nightly prices starting at
Mira Mesa vacation rentals start at ﺩ.ﺇ 73 per night before taxes and fees

Verified guest reviews
Over 12,420 verified reviews to help you choose

Family-friendly vacation rentals
120 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Vacation rentals with a pool
70 properties feature pools

Rentals with dedicated workspaces
190 properties have a dedicated workspace

Wi-Fi availability
290 of Mira Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mira Mesa rentals

4.8 Average rating
Mira Mesa stays are highly rated by guests—averaging 4.8 out of 5!
Destinations to explore
- Rentals with outdoor seating Mira Mesa
- Fitness-friendly rentals Mira Mesa
- House rentals Mira Mesa
- Rentals with a hot tub Mira Mesa
- Family-friendly rentals Mira Mesa
- Rentals with a patio Mira Mesa
- Rentals with a beach view Mira Mesa
- Private suite rentals Mira Mesa
- Rentals with a fire pit Mira Mesa
- Rentals with pools Mira Mesa
- Rentals with a washer and dryer Mira Mesa
- Pet-friendly rentals Mira Mesa
- Rentals with a fireplace Mira Mesa
- Rosarito Beach
- San Diego Convention Center E Ent
- SeaWorld San Diego
- Petco Park
- University of California-San Diego
- Oceanside City Beach
- San Diego Zoo Safari Park
- Ocean Front Walk
- Pacific Beach
- San Diego Zoo
- Coronado Beach
- Torrey Pines State Beach
- Tijuana Beach
- Balboa Park
- Pechanga Resort Casino
- San Diego State University
- San Clemente State Beach
- LEGOLAND California
- Mission Beach
- Moonlight State Beach
- Liberty Station
- San Onofre Beach
- Oceanside Harbor
- Sesame Place San Diego





