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Vacation rentals in Mira Mesa

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mira Mesa

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
The exterior of a stone studio is seen at dusk, featuring an arched entrance framed by natural stone walls. Steps lead to a small patio area, with expansive views of the surrounding landscape, including distant city lights and the twilight sky.
Cave in Lake San Marcos
5 out of 5 average rating, 105 reviews

Casa Grotto, Romantic Stone Cottage w/ Ocean Views

Perched 800ft above sea level with panoramic ocean views from La Jolla to Catalina Island, Casa Grotto is a unique stone studio carved into the ocean view hillside of Lake San Marcos . Built in the 80's using stone from the mountain, the space was updated in 2025 with modern touches—featuring a rock shower, full kitchen, AC, and gym. Just 20 minutes from the beach, it’s a dreamy escape for surfers, hikers, and couples looking for a romantic getaway. No pets—our two friendly boxers live on-site

Superhost
Guest suite in Mira Mesa
5 out of 5 average rating, 4 reviews

Bright Private Suite • Kitchen+AC+WD/Patio+Parking

Relax in this beautifully designed private 1-bedroom, 1-bath home featuring with patio, modern finishes, dedicated parking, EV charging, AC, fast Wi-Fi, Smart TV, fully equipped kitchen, and in-unit washer & dryer. Walk to grocery stores, cafes & restaurants • 5 mins to Miramar & Sorrento Valley • Easy freeway access to airport & attractions: La Jolla, Balboa Park, SD Zoo, SeaWorld & Legoland Guest Access ✔️ Private parking spot in driveway ✔️ Full access to kitchen ✔️ In-unit washer & dryer

Top guest favorite
An open living area showcases modern furnishings, including a light gray sectional sofa and a sleek coffee table. A workspace with a desk and chair is positioned near a window, while a bright kitchen area features stylish cabinetry and countertops visible in the background.
Home in Rancho Penasquitos
4.94 out of 5 average rating, 130 reviews

Peaceful in Penasquitos

NO AIRBNB FEES ARE CHARGED TO GUEST. Relax with the friends and family at this peaceful place to stay. Newly remodeled kitchen, bathrooms, appliances. Child friendly. Property is off of 56 Freeway and Rancho Peñasquitos Blvd. Driving Distance: 25 mins from San Diego Convention Center 25 min from San Diego International Airport 30 mins from Legoland (North County) 20 mins from San Diego Safari Park Zoo (North County) 25 mins from San Diego Zoo 25 mins from Mission Bay 25 mins from Downtown

Top guest favorite
A private yard is illuminated with string lights, highlighting the artificial grass area. A patio extends from the back of the suite, with a white fence enclosing the space. The contrasting dark sky adds depth to the peaceful outdoor setting.
Guesthouse in Mira Mesa
4.94 out of 5 average rating, 142 reviews

Perfect Home Base for Family Adventures

Welcome to our cozy Mira Mesa guesthouse in San Diego! This private 600 sq ft suite is perfect for families, friends, and pet-friendly stays. Enjoy a brand-new sofa bed (Sept 13, 2025) plus recent updates including a side bed, added storage, new wall décor, and curtains (Mar 22, 2026). The space also features a bright workspace with fast WiFi—ideal for remote work. Conveniently located near Freeway 15, you’re just 15–20 minutes from beaches, downtown, and top San Diego attractions.

Guest favorite
A spacious room is furnished with a plush brown sectional sofa adorned with red accent pillows and an ottoman. A large bed with neutral bedding is positioned nearby, and framed artwork adds subtle elegance to the wall, complemented by soft ceiling lights that enhance the inviting space.
Guest suite in Mira Mesa
4.91 out of 5 average rating, 154 reviews

Stunning Private Entrance 2bd/1ba Suite

Located in the heart of San Diego, guests are a short drive or bus ride to all the local hotspots. Shopping and restaurants are within walking distance. The space itself is large, exquisitely decorated, has a dedicated driveway parking space and its own private entrance in the front of the house. Also available are the washer/dryer for laundry, beach equipment, electric bikes (with signed waiver), cribs/toys/etc. for children. Short drive to SeaWorld, Zoo, Safari Park and beaches.

Guest favorite
An open living space features a comfortable sofa facing a mounted television. A stone accent wall complements the modern design. In the background, a fully equipped kitchen and dining area are visible, with natural light streaming through large windows.
Home in Mira Mesa
4.83 out of 5 average rating, 264 reviews

Modern Kitchen Zen Backyard Putting Green with AC

Our beautiful home is located in the heart of San Diego. From the living room front door you'll see through to the kitchen, family room, and straight into the wide backyard with a putting green. Set up perfectly for family gatherings. Kitchen comes fully equipped. - Thermador stove, down vent hood, microwave, oven, and wide island Backyard perfect for a gathering: Safe and clean for the kids to run around. Has putting green, fire pit, and multiple lounge areas.

Guest favorite
An open-concept living space is displayed, featuring a modern sofa, a round coffee table, and a dining area with black chairs. Natural light is provided through large windows, and a well-equipped kitchen with bar seating is visible in the background.
Home in Bay Ho
4.87 out of 5 average rating, 105 reviews

Luxury 2 bedroom home with BBQ

Beautiful 2-Bedroom in San Diego with a Gorgeous Backyard Welcome to your dream stay in sunny San Diego! This stylish and cozy 2-bedroom home offers the perfect blend of comfort, relaxation, and outdoor charm—featuring a gorgeous backyard ideal for lounging or dining under the stars. Parking Info: Driveway parking is available—please pull all the way up to the garage. There’s also plenty of free street parking nearby. -All bedrooms have black out curtains

Guest favorite
Home in Mira Mesa
4.97 out of 5 average rating, 35 reviews

A Romantic Family Retreat Home - Game room-Hot tub

Your Romantic Getaway in Central SD Awaits! Escape to this central beachy, 4BR/3BA home, perfect for relaxing getaway family. Designed with comfort, fun, and relaxation in mind, it features open living spaces, a fully stocked kitchen, and a spacious backyard with hot tub and plenty of activities. The game room offers a pool table and arcade games—fun for all ages. A perfect spot to relax, recharge, and make great memories with your loved ones!

Top guest favorite
A spacious bedroom features a black metal bed frame with patterned bedding. A small bedside table is positioned beside the bed. Natural light fills the room through a large window, which is adorned with light-colored curtains that complement the neutral walls.
Guesthouse in Mira Mesa
4.94 out of 5 average rating, 93 reviews

Gated Detached Large House Convenient/Quiet

The spacious detached casita/guest house comes with private entrance and a backyard. It has a large bedroom, walk-in closet, full bathroom, living dinning, and kitchen. The kitchen has new sink, stove/oven, refrigerators, essential cookware, utensils, and tableware. The house has a queen size bed that can sleep two adults, a sofa sleeper bed and a queen size air mattress for additional guests. Guest may use the new LG washer/dryer combo unit.

Top guest favorite
A single-story ranch home is set amidst a landscaped front yard featuring vibrant green grass and white gravel accents. A large tree provides shade by the entrance, while a well-maintained driveway leads to a garage. Clear skies add to the welcoming exterior ambiance.
Home in Mira Mesa
4.98 out of 5 average rating, 99 reviews

Charming Family 3BR w/ Game Room

Experience San Diego living in this welcoming 3-bed, 2-bath Mira Mesa home. Perfect for families with a fun game room for entertainment and a spacious backyard featuring covered patio seating and grill for outdoor dining. Minutes from scenic hiking trails, family-friendly parks, and beautiful beaches. Easy access to diverse local restaurants. Your ideal Southern California base with space for both lively gatherings and relaxing downtime.

Top guest favorite
A spacious living room features a high, beamed ceiling and large windows allowing natural light. Comfortable seating includes a blue sofa and two armchairs, arranged around a central coffee table. A stone fireplace and decorative plants add to the inviting ambiance.
Home in Mira Mesa
4.94 out of 5 average rating, 127 reviews

Open Concept modern ranch w/ bounce house included

Come and relax at our California ranch style family friendly home which is a 1 story (no stairs) 3 bedroom 2 bath home in Sunny San Diego.. This open concept home has two living rooms and a backyard patio to grill and lots of grass for the kiddos to run around in. This house is centrally located in San Diego and a quick drive to the beach, the San Diego Zoo, local hospitals, Petco Park for padres, Legoland, and downtown San Diego.

Guest favorite
A cozy sleeping area features a spacious bed with a blue blanket and decorative pillows. Soft lighting is provided by two bedside lamps on dark wooden nightstands. A bright piece of wall art hangs above the bed, and a clothing rack is positioned nearby.
Home in Mira Mesa
4.89 out of 5 average rating, 112 reviews

Charming & Spotless Studio with Own Entry

Entire Private Studio Suite. Brand new updated entire suite with 1 Queen Bed & 1 Full bathroom. Ideal for couples, solo adventurers, and business travelers. Just minutes from central of shopping and food like Asian restaurants, markets as well as 24h stores, Edward Cinema, etc... Less than 20 mins to Balboa Park, La Jolla Shores Park, Solana Beach, Moonlight Beach, San Diego Zoo, San Diego Sea World.

Popular amenities for Mira Mesa vacation rentals

Quick stats about vacation rentals in Mira Mesa

  • Total vacation rentals

    Explore 290 vacation rentals in Mira Mesa

  • Nightly prices starting at

    Mira Mesa vacation rentals start at ﺩ.ﺇ 73 per night before taxes and fees

  • Verified guest reviews

    Over 12,420 verified reviews to help you choose

  • Family-friendly vacation rentals

    120 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 60 rentals that welcome pets

  • Vacation rentals with a pool

    70 properties feature pools

  • Rentals with dedicated workspaces

    190 properties have a dedicated workspace

  • Wi-Fi availability

    290 of Mira Mesa vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Mira Mesa rentals

  • 4.8 Average rating

    Mira Mesa stays are highly rated by guests—averaging 4.8 out of 5!

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