
Vacation rentals in Mira Mesa
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Top-rated vacation rentals in Mira Mesa
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Charming Guest House in Poway - Kid friendly
Welcome to our cozy and private 1 bed/1 bath guest house, nestled in the heart of Poway. Our space offers a queen-sized bed, spacious bathroom with a walk-in shower, a living area and kitchen with large windows providing great natural lights. The kitchenette is well-equipped for you to channel your inner chef and comes with a fully stocked coffee/tea station. Stay connected with high-speed Wi-Fi and unwind with Smart TV entertainment. Enjoy the luxury of a private entrance for added privacy.

Casa Grotto, Romantic Stone Cottage w/ Ocean Views
Perched 800ft above sea level with panoramic ocean views from La Jolla to Catalina Island, Casa Grotto is a unique stone studio carved into the ocean view hillside of Lake San Marcos . Built in the 80's using stone from the mountain, the space was updated in 2025 with modern touches—featuring a rock shower, full kitchen, AC, and gym. Just 20 minutes from the beach, it’s a dreamy escape for surfers, hikers, and couples looking for a romantic getaway. No pets—our two friendly boxers live on-site

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV
Welcome to your personal resort! This is your private Guest House with a salt & heated pool + hot tub. Located in a very quiet & safe neighborhood in beautiful San Diego. Drive 15 minutes to the beach, downtown, La Jolla, Zoo, stadiums, Sea World, Convention Center + more. Hike next door at Cowell Mountain or Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo, top quality finishes & furniture. Everything you need for memorable vacation! No smoking or vaping on the property.

Private Apartment - Secluded 2 Acre Estate/Orchard
Enjoy our serene and beautiful loft apartment in south Rancho Santa Fe. Quiet and completely private retreat on garden like 2 acre farm estate with orchard. Kid friendly and just minutes from the beach, fair grounds, restaurants, golf, horse riding, hiking, and shopping. This spacious 900 sq ft. getaway includes wifi, 2 smart ROKU TVs, full kitchenette, dining table, King bed, additional two twin XL beds. 7 miles from the beach, 2.5 miles from Trader Joe's and multiple restaurants.

Perfect Home Base for Family Adventures
Welcome to our cozy Mira Mesa guesthouse in San Diego! This private 600 sq ft suite is perfect for families, friends, and pet-friendly stays. Enjoy a brand-new sofa bed (Sept 13, 2025) plus recent updates including a side bed, added storage, new wall décor, and curtains (Mar 22, 2026). The space also features a bright workspace with fast WiFi—ideal for remote work. Conveniently located near Freeway 15, you’re just 15–20 minutes from beaches, downtown, and top San Diego attractions.

Stunning Private Entrance 2bd/1ba Suite
Located in the heart of San Diego, guests are a short drive or bus ride to all the local hotspots. Shopping and restaurants are within walking distance. The space itself is large, exquisitely decorated, has a dedicated driveway parking space and its own private entrance in the front of the house. Also available are the washer/dryer for laundry, beach equipment, electric bikes (with signed waiver), cribs/toys/etc. for children. Short drive to SeaWorld, Zoo, Safari Park and beaches.

Contemporary Family-Friendly Home in SD with EV&AC
Welcome to San Diego, the city of sun and fun. This newly-renovated, spacious home has 3 beds and 2 baths with central AC, and is conveniently located in the center of San Diego with easy access to freeways 5, 805 and 15. It's close to many attractions -Legoland, Sea World, San Diego Zoo, Balboa Park, and beautiful beaches. The neighborhood has a variety of restaurants, cafes, movie theater, shopping center, and grocery stores. Just a few minutes from Sorrento Valley and UCSD.

Modern Kitchen Zen Backyard Putting Green with AC
Our beautiful home is located in the heart of San Diego. From the living room front door you'll see through to the kitchen, family room, and straight into the wide backyard with a putting green. Set up perfectly for family gatherings. Kitchen comes fully equipped. - Thermador stove, down vent hood, microwave, oven, and wide island Backyard perfect for a gathering: Safe and clean for the kids to run around. Has putting green, fire pit, and multiple lounge areas.

Luxury 2 bedroom home with BBQ
Beautiful 2-Bedroom in San Diego with a Gorgeous Backyard Welcome to your dream stay in sunny San Diego! This stylish and cozy 2-bedroom home offers the perfect blend of comfort, relaxation, and outdoor charm—featuring a gorgeous backyard ideal for lounging or dining under the stars. Parking Info: Driveway parking is available—please pull all the way up to the garage. There’s also plenty of free street parking nearby. -All bedrooms have black out curtains

Artist micro-villa with kitchen, firepit & theater
Not only is your stay private and chic, but its location is unbeatable: >apx 10 mins to La Jolla beaches and Pacific Beach restaurants/bars > apx 10 mins to SD zoo, Hillcrest nightlife and North park > apx 15-20 mins to Del Mar and Solana beaches and Encinitas As you enter this cozy San Diego gem, you are welcomed by many hand built and artistic thing to make you feel like you are at home! From hand built coffee and dining table, to painted murals.

Open Concept modern ranch w/ bounce house included
Come and relax at our California ranch style family friendly home which is a 1 story (no stairs) 3 bedroom 2 bath home in Sunny San Diego.. This open concept home has two living rooms and a backyard patio to grill and lots of grass for the kiddos to run around in. This house is centrally located in San Diego and a quick drive to the beach, the San Diego Zoo, local hospitals, Petco Park for padres, Legoland, and downtown San Diego.

STUDIO 56
Entire Private Studio Suite. The entire suite is brand new and updated with 1 queen bed, 1 double bed, and 1 full bath. Quiet midtown of Mira Mesa central drive in San Diego. Studio fully equipped with 2 beds, a leather sofa, working desk, kitchenette meant for light food warm, full size refrigerator, single sink meant for light cup and dish wash All shops, restaurants, a cinema within minus drive about 2 miles away.
Popular amenities for Mira Mesa vacation rentals
Other great vacation rentals in Mira Mesa

Town house 3Bdr/2.5Br Fully furnished San Diego

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Amazing Views - Central Location & Close to SDSU

Sunny SD Escape| Sleeps 8 | Beach, Zoo & Downtown

Beautiful 3Bedroom Home in the Heart of Mira Mesa

Sunset House

Cozy & Modern Family Home in Mira Mesa
Quick stats about vacation rentals in Mira Mesa

Total vacation rentals
Explore 290 vacation rentals in Mira Mesa

Nightly prices starting at
Mira Mesa vacation rentals start at ﺩ.ﺇ 73 per night before taxes and fees

Verified guest reviews
Over 12,420 verified reviews to help you choose

Family-friendly vacation rentals
120 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Vacation rentals with a pool
70 properties feature pools

Rentals with dedicated workspaces
190 properties have a dedicated workspace

Wi-Fi availability
290 of Mira Mesa vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mira Mesa rentals

4.8 Average rating
Mira Mesa stays are highly rated by guests—averaging 4.8 out of 5!
Destinations to explore
- House rentals Mira Mesa
- Rentals with outdoor seating Mira Mesa
- Rentals with a hot tub Mira Mesa
- Rentals with a fire pit Mira Mesa
- Rentals with pools Mira Mesa
- Private suite rentals Mira Mesa
- Family-friendly rentals Mira Mesa
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- Rentals with a washer and dryer Mira Mesa
- Rentals with a patio Mira Mesa
- Fitness-friendly rentals Mira Mesa
- Rentals with a fireplace Mira Mesa
- Rentals with a beach view Mira Mesa
- Rosarito Beach
- San Diego Convention Center E Ent
- SeaWorld San Diego
- Petco Park
- University of California-San Diego
- Oceanside City Beach
- San Diego Zoo Safari Park
- Ocean Front Walk
- Pacific Beach
- San Diego Zoo
- Coronado Beach
- Torrey Pines State Beach
- Tijuana Beach
- Balboa Park
- Pechanga Resort Casino
- San Diego State University
- San Clemente State Beach
- LEGOLAND California
- Mission Beach
- Moonlight State Beach
- Liberty Station
- San Onofre Beach
- Oceanside Harbor
- Sesame Place San Diego





