
Vacation rentals in Midlands of South Carolina
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Midlands of South Carolina
Guests agree: these stays are highly rated for location, cleanliness, and more.

Relax and unplug at this private oasis!
Our beautiful cottage for adults only is set on a private spring fed pond with all amenities to unwind from the day-to-day hustle. A porch with rocking chairs, brick fire pit and outdoor lighting in the courtyard make this your destination for relaxation. Take a walk in the 20 acres of wooded trails, fish, kayak, paddleboat, read a book, write, listen to music or just take a nap. This property lets you unplug from the world, relax, and connect with nature without giving up modern conveniences.

A relaxing cabin on private pond. Old Bells Secret
Escape to our secluded cabin on 90 acres in St. Matthews, SC! This early 2000s style cabin features 2 cozy bedrooms, 1 bathroom, and a lovely porch. The large pond is perfect for swimming, fishing, or playing. It’s an endless adventure. The house can sleep up to 6 with the pull out couch. Accessible via a private road, it's perfect for weekend getaways with the family or housing for workers. Experience relaxation and adventure in nature at this wonderful cabin. Book now for a memorable stay!

The Farmhouse @ Goat Daddy's
Nestled on 66 acres with a gorgeous pond/farm view, you will find Goat Daddy's Farm and Animal Sanctuary. Our luxurious tiny house has everything you need to make your farm stay comfortable and relaxing. Guests will have access to the farm during specific hours, as well as over 2.5 miles of paths and two ponds to explore. With your feet in the sand, by a fire, in the hot tub, on the trails, or getting some goat/animal therapy, The Farmhouse and Sanctuary has something to offer for all.

Sunset Cove-Beautiful Lake views
Your home away from home on Lake Murray! Spacious, modern clean, home with 3 levels of living -3 spacious decks, screen porch, and sunroom all with massive lake views! Plenty to do at Sunset Cove relaxing with family and friends and toys galore! "Wow just wow, best Airbnb ever..Sarah, June 2026. "..clean, beautiful view and so many fun games..Lisa, Oct 2025."Perfect setting for a quiet getaway. The house was amazing, clean, and had all the amenities we were looking for.."Jay, Sept 2025

10 Mile View on Lake Murray w/ Dock and Ramp
Enjoy our Waterfront getaway on Lake Murray. It includes a private boat ramp, private dock, and over 600 sq ft deck across the entire lake front of the home. The front yard is large and perfect for cornhole, frisbee, and other activities. This cove is known for excellent kayaking, fishing, boating, and watersports. We have included 2 Kayaks and we work directly with a pontoon rental company if you would like a boat delivered. The .4 acre lot has plenty of parking for all guests.

Golden Reflections Getaway
Welcome to the Golden Reflection Getaway—a spacious, stylish retreat perfect for families and groups. Enjoy this 2,600+ sq. ft. spacious family area with three luxury themed bedrooms upstairs and extra sleeping options with a full bathroom on the main level. Tucked away in a peaceful neighborhood, just 7 minutes from the vibrant heart of Downtown Columbia and 18 minutes from Fort Jackson. Relax, recharge, and make lasting memories in this thoughtfully designed and comfortable home.

Big Water Sunset at Lake it Easy
Escape to Beautiful Lake Wateree for a relaxing weekend away with friends or family. This updated house features 2 bedrooms & 2 bathrooms. Enjoy the cozy vibes of a tastefully decorated space, perfect for unwinding after a day on the lake. Step outside to a serene screened in porch, a fire pit, and stunning big water sunsets that will take your breath away. Whether you're into fishing, kayaking, or simply relaxing by the water, this lakefront house has something for everyone!

Luxury Treehouse in the heart of Columbia
Mid-Century Modern Treehouse with no stairs to climb but walk across a bridge thru beautiful professionally landscaped gardens onto a spacious deck with a hot tub. The view is over a bubbling creek set back into the woods. The barbecue grill and fire pit area complete with a twinkling chandelier and string lights. Relax inside and curl up and watch a movie in front of the fireplace! You have parking next to a walkway located between the treehouse and gardens next to our home.

Elmwood Retreat for Remote Work & Family Fun
Come and enjoy your stay at Elmwood Retreat, a beautifully renovated 4 BR home in historic Elmwood Park. Built in 1905 and updated with modern comfort, it's perfect for remote work, family trips or extended stays. Enjoy high-seed Wi-Fi, a dedicated workspace, and a peaceful neighborhood. Steps from Main Street and the Vista and close to Riverwalks, museums, parks and Colonial Life Arena, this home offers charm, safety and convenience, for every guest to feel home.

Congaree Vines - Woodland Cottage by a Vineyard!
-Enjoy a Quiet Country Stay! This charming European style cottage is set by a Hobby Vineyard! Enjoy complimentary port wine from our vineyard, a fire pit and hammock under the stars! -Congaree Vines also has the Barn Bungalow. Pets are welcome for a fee. If service dog, bring paperwork. -We are near Congaree National Park (33 min), Columbia, USC, Ft. Jackson, Airport I-26 & Hwy 77. -15% off Guided Kayak in CNP w/Carolina Outdoor Adventures.

Historic Log cabin on private fishing lake
Magnificent historic Log Cabin located on the shores of a private 10 acre lake surrounded by over hundreds of acres of forested isolation. One mile into the woods and away from the stress, hustle and bustle of everyday life. Access to 100 acre parcel for walking trails, fishing, canoeing, swimming, campfire and wildlife. Great opportunity to unplug from the stress and engage with family and friends! A great spot for an artist retreat!

Lazy Creek Cove Cottage w EV Plug!
Welcome to Lazy Creek Cove Cottage - your luxurious lakefront retreat! This charming Airbnb offers a serene getaway with a hot tub, private dock, paddle boards, kayaks,a fire pit, and a NEMA 14-50 outlet for EV charging or Camper. Enjoy a cozy living space, well-equipped kitchen, comfortable bedrooms, and reliable internet access. Immerse yourself in nature's beauty, explore the nearby attractions in Chapin.
Popular amenities for Midlands of South Carolina vacation rentals
Other great vacation rentals in Midlands of South Carolina

Quiet creekside home with large deck

Otto the Airstream

Charming Country Cottage Nestled in the Woods

Private 75 acre farm with lake

The Carolina Cottage: Near Ft Jackson, Zoo & 5pts!

The Farm House

Lakefront w/Private Dock + Fenced Yard.

Skylight Spa Cottage - USC, FT. J, Williams-Brice
Destinations to explore
- Atlanta Vacation rentals
- Myrtle Beach Vacation rentals
- Charlotte Vacation rentals
- Gatlinburg Vacation rentals
- Savannah Vacation rentals
- Charleston Vacation rentals
- Jacksonville Vacation rentals
- Pigeon Forge Vacation rentals
- Hilton Head Island Vacation rentals
- North Myrtle Beach Vacation rentals
- Raleigh Vacation rentals
- Asheville Vacation rentals
- Congaree National Park
- Riverbanks Zoo and Garden
- University of South Carolina
- Williams Brice Stadium
- South Carolina State House
- South Carolina State Museum
- Columbia Museum of Art
- Colonial Life Arena
- West Columbia Riverwalk Park and Amphitheater
- Saluda Shoals Park
- Sesquicentennial State Park
- Dreher Island State Park
- Columbia Metropolitan Convention Center
- Edventure
- Riverfront Park
- Soda City Market
- Koger Center for the Arts
- Lake Murray Dam North Recreational Area
- Frankie's Fun Park
- Segra Park





