Vacation rentals in Madison County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Madison County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Apartment in Edwardsville

4.91 out of 5 average rating, 223 reviews

Edwardsville Apartment - The Woodland Suite

The apartment in the lower level of the home has recently been renovated, with a walk-out private entrance, a full kitchen & dining area, full bath, bedroom and a cozy living space. Situated just 35 minutes from downtown St Louis, in the safe and affluent community of Edwardsville, this property sits in a quiet cul de sac on a wooded lot right in the heart of the city. We are just a few minutes from the SIUE campus, Edwardsville HS, & I-270. Coffee/restaurants/shops/parks/trails just 2 min away.

Jul 9 – 16

ﺩ.ﺇ540 per night
Guest favorite

Home in Granite City

4.98 out of 5 average rating, 119 reviews

Cozy 2-bedroom home minutes from ST. Louis, MO

Welcome to the Sheridan House. This cozy 2-bedroom home is located in a quiet neighborhood. It sets on a corner lot with a large back yard and a parkway across the street. Spend relaxing evenings on the patio, grilling your dinner. Or challenge your partner to a game of ping pong in the basement rec room. Centrally located, you can spend your days exploring attractions in Saint Louis, Mo, Alton and Edwardsville, IL. Just minutes from World Wide Technology Raceway, Busch Stadium, & the Arch.

Oct 12 – 19

ﺩ.ﺇ425 per night
Guest favorite

Home in Alton

4.99 out of 5 average rating, 130 reviews

Home Away from Home! Historic with Modern Comforts

You'll love this charming 1,750 sq ft home on 1/3 acre in a prestigious & quiet historic Alton-Godfrey neighborhood. High-end comfy beds, nice bath towels, newly painted with hardwood floors and Totally remodeled Kitchen. Central A/C & Heat, abundant natural lighting & outdoor patio living. High-speed wireless internet & local TV channels on the Big Screen HDTV. Impeccably clean & maintained for your ultimate comfort & enjoyment! (NO Parties, Gatherings or Events). PLEASE READ HOUSE RULES!

Apr 7 – 14

ﺩ.ﺇ702 per night

Popular amenities for Madison County vacation rentals

Other great vacation rentals in Madison County

Guest favorite

Home in Florissant

5.0 out of 5 average rating, 5 reviews

Recently Renovated Townhome

May 29 – Jun 5

ﺩ.ﺇ444 per night
Superhost

Barn in Alhambra

4.84 out of 5 average rating, 58 reviews

Boho Barn Loft Countryside Getaway

Apr 27 – May 2

ﺩ.ﺇ629 per night
Guest favorite

Home in Edwardsville

5.0 out of 5 average rating, 35 reviews

Historic Leclaire Cottage on the Park

Dec 4 – 11

ﺩ.ﺇ1,051 per night
Guest favorite

Home in Granite City

4.93 out of 5 average rating, 41 reviews

"Blue Bliss Retreat in Granite"n

Jun 11 – 18

ﺩ.ﺇ358 per night
Guest favorite

Home in Alton

4.82 out of 5 average rating, 84 reviews

Backyard Seclusion Cottage

May 13 – 20

ﺩ.ﺇ476 per night
Guest favorite

Home in Edwardsville

4.95 out of 5 average rating, 95 reviews

The Brick B&B - Entire House Downtown Edwardsville

Sep 3 – 10

ﺩ.ﺇ917 per night
Guest favorite

Home in Edwardsville

4.97 out of 5 average rating, 92 reviews

The Kansas Street Guest House

Dec 23 – 30

ﺩ.ﺇ1,691 per night
Superhost

Apartment in Saint Jacob

5.0 out of 5 average rating, 5 reviews

A Sweet Spot, catering to Traveling Tech/workers

Aug 23 – 30

ﺩ.ﺇ253 per night
Superhost

Cottage in Staunton

5.0 out of 5 average rating, 13 reviews

Luxury Lakeview Bungalow #14 near St. Louis

Apr 15 – 22

ﺩ.ﺇ541 per night
Guest favorite

Home in Highland

5.0 out of 5 average rating, 49 reviews

Beautiful craftsman style home, built in 1930.

Nov 29 – Dec 6

ﺩ.ﺇ1,717 per night
Guest favorite

Home in Alton

5.0 out of 5 average rating, 29 reviews

Riverview Home-The Brown Bag Bistro Bungalow

Aug 18 – 25

ﺩ.ﺇ638 per night
Superhost

Home in St. Louis

4.91 out of 5 average rating, 11 reviews

Cozy Retreat St. Louis County Home

Jul 11 – 18

ﺩ.ﺇ296 per night

Destinations to explore