Vacation rentals in Lofton's Island

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Top-rated vacation rentals in Lofton's Island

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Guest favorite
An outdoor seating area is illuminated by string lights at night, featuring two wicker chairs positioned beside a small table. A colorful mural with leaf patterns decorates the wall, while a grill is placed to the right on a paved surface.
Home in Fort Myers
4.95 out of 5 average rating, 122 reviews

Free cleaning! hot tub/jacuzzi, grill & yard!

Relax with the whole family at this peaceful home in the heart of Fort Myers. This spacious pet friendly house is full of natural light and has everything you need for the perfect Florida vacation. This fully furnished home has 3 bedrooms and 2 full bathrooms, as well as a laundry room, kitchen, large expanded living area, and hot tub & grill area. Centrally located a short drive from shops and restaurants in historic downtown along the Caloosahatchee River, parks, and the Edison/Ford Museum.

Top guest favorite
A spacious room features a king-sized bed with a light quilt, flanked by bedside tables with decorative lamps. A wall-mounted television is positioned over a mini-fridge. Two bar stools are placed at a small table, complemented by wooden flooring and soft wall decor.
Farm stay in Fort Myers
4.99 out of 5 average rating, 243 reviews

Private farmhouse stay at Dim Jandy Ranch.

Take it easy at this unique and tranquil getaway. A beautifully appointed bed and bath in a separate building from the house. We have goats, donkeys and chickens and a Highland cow, all super friendly. Sit and relax on your private, beautiful lanai or any of our farm tables placed around the property. Join us as we feed the animals. Or even join in one of our Goat Yoga classes! We're easily located close to I-75, airports, shopping, beaches, downtown. Perfect for couples or solo travelers.

Top guest favorite
A bright and airy room features a king-sized bed with plush linens, framed by soothing blue walls. A flat-screen TV is mounted on the wall, and two patterned chairs are positioned to enjoy the view. Large glass doors open to a private patio overlooking the water.
Guesthouse in Fort Myers
4.94 out of 5 average rating, 149 reviews

Get Away to the Mango Cottage

Nestled on the outskirts of Historic downtown Fort Myers abides the Mango Cottage overlooking the Caloosahatchee River. The sunsets are amazing. You will enjoy the luxurious linens on the King sized bed to the relaxing patio it will delight the senses. You will be able to enjoy the 60" flat screen Smart TV! . The cottage is complete with Keurig coffee maker, toaster, microwave/convection oven and grill outside. We are minutes from restaurants and night life. This is a NON-SMOKING property.

Top guest favorite
Apartment in Fort Myers
4.9 out of 5 average rating, 21 reviews

Blue Paradise

This waterfront apartment blends unique character with an inviting sense of comfort. Thoughtfully styled with warm textures and distinctive design details, the space feels both curated and effortlessly cozy. Soft furnishings, subtle coastal accents, and a relaxed layout make the apartment feel like a peaceful retreat—an intimate, stylish haven where modern living meets the calming rhythm of the water. The place has 1 bedroom , one comfortable king bed ,and one air mattress and space to use

Top guest favorite
Home in North Fort Myers
5 out of 5 average rating, 11 reviews

5 min to DT- Chic Home, Tropical Yard w/ Fire Pit

Welcome to Casa Seren, a restored 1946 mid-century retreat where modern comfort meets timeless charm. Bright, airy spaces and thoughtful décor create a calming atmosphere throughout. Step outside to a lush garden with a soothing fountain, cozy fire pit, and inviting dining area. The private tiny house offers a peaceful spot for yoga, meditation, or quiet reflection. Just 5 minutes from downtown and close to the beaches, Casa Seren is the perfect place to relax, unwind, and feel at home.

Guest favorite
Apartment in Fort Myers
5 out of 5 average rating, 19 reviews

Luxury Apartment & View – Perfect for Your Stay

Experience the ultimate Florida getaway in this luxurious and comfortable apartment. Bright, airy space with a private balcony, where you can wake to sunlit mornings and enjoy city, river, and greenery views. Fully equipped with everything you need for a seamless, relaxing stay, smart lighting, Wi-Fi, and cable TV. Enjoy resort-style amenities: pool, gym, sauna, jacuzzi. Minutes from Fort Myers riverwalks, dining, shopping, and culture — the final touch for your unforgettable vacation.

Top guest favorite
Apartment in Fort Myers
4.94 out of 5 average rating, 53 reviews

Executive King Suite City View | Downtown Ft Myers

Welcome to Your Luxe Living Getaway! Experience the perfect mix of comfort and sophistication in this Executive King Suite with City Views, located in the heart of Downtown Fort Myers. This modern 1-bedroom condo features a plush king bed and a queen-size pull-out sofa, ideal for couples, professionals, or small families. Enjoy city views, a fully equipped kitchen, and access to premium amenities all just steps from the best dining, shopping, and entertainment in Fort Myers.

Guest favorite
Apartment in Fort Myers
4.94 out of 5 average rating, 35 reviews

Luxury II

Because one wasn’t enough… we’re opening Luxury 2 🥂 Experience even more elegance and the same breathtaking river views you loved. This brand-new unit blends modern luxury, romantic vibes, and unforgettable sunsets. 📍 In the heart of Downtown Fort Myers, steps from top restaurants, bars, and art. 🛏️ Stylish interiors | 🌅 Floor-to-ceiling views | 🏊 Resort amenities | 🍷 Romantic & vibrant Luxury 2—your escape to unforgettable memories. #Luxury2 #LuxuryInTheSky

Guest favorite
Condo in Fort Myers
5 out of 5 average rating, 11 reviews

Level 19 | King Suite | Views | Pool+HotTub+Gym

Welcome to Level 19, a modern 19th-floor retreat in Downtown Fort Myers. Enjoy beautiful skyline views, warm décor, and a fully equipped kitchen. Relax in the living area with Queen sofa bed and unwind at the pool, hot tub, or gym. Designed for comfort, this King suite hosts up to four guests. City Views | Pool | Hot Tub | Gym | King Bed | Queen Sofa Bed | Wi-Fi | Smart TV Dining: 2–5 min walk | Edison & Ford 5–10 min | Fort Myers Beach 25–30 min | RSW 25 min

Top guest favorite
Home in North Fort Myers
4.95 out of 5 average rating, 20 reviews

Secret Hideaway North Fort Myers

8 minutes to Historic Downtown Fort Myers. Alan Vallejera offers an exquisite luxury home, nestled in lush tropical settings. Ours Property is adult-only with a minimum age requirement of 25. Carefully curated to provide an unparalleled experience of comfort and elegance, surrounded by natures beauty and luxurious amenities designed to make your stay unforgettable. This rental is the perfect setting for a romantic vacation or relaxing staycation!

Top guest favorite
A modern open-plan living area features a sleek leather sofa paired with a contrasting armchair, set against light walls and a stylish area rug. The space is illuminated by natural light from multiple windows, with access to a contemporary kitchen seen in the background.
Townhouse in Fort Myers
4.99 out of 5 average rating, 151 reviews

Chic & Cozy River District Townhouse

This townhouse is in the heart of the River District, making it easy to plan your visit. For the young or young at heart, you can enjoy the downtown entertainment on foot or from the comfort of your own Chic City Townhouse. Park your car in front and you'll never need to leave. Walk to any one of numerous restaurants. Whether you want to curl up and enjoy a movie on the 77 inch tv or walk to the Edison Home, it's all at your fingertips.

Top guest favorite
A spacious entryway is highlighted by light gray walls and large windows that allow natural light to fill the area. A console table with a framed picture and greenery adds a decorative touch. The open layout leads into a modern kitchen and living space.
Home in Punta Gorda
4.97 out of 5 average rating, 31 reviews

Where the Black Top Ends

Escape to your dream getaway in our brand-new, Airbnb haven. Nestled on 5 sprawling acres, this serene retreat offers breathtaking lake views and an enchanting woodland backdrop, promising the perfect blend of tranquility and adventure. 2 Minutes to the Babcock Ranch Community, 10 minutes to the interstate, and 20 min from downtown. Our home has every detail thoughtfully crafted to provide you with a comfortable & memorable stay.

Popular amenities for Lofton's Island vacation rentals

  1. Airbnb
  2. United States
  3. Florida
  4. Lee County
  5. Fort Myers
  6. Lofton's Island