Vacation rentals in Lake Keowee

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Top-rated vacation rentals in Lake Keowee

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Top guest favorite
A serene lake view is captured at sunset, featuring a dock and pavilion extending into the water. Lush grasses and landscaped stones frame the scene, as warm sunlight bathes the area in golden tones, enhancing the tranquil atmosphere of the shoreline.
Cottage in Six Mile
4.99 out of 5 average rating, 203 reviews

Lake Keowee Waterfront Cottage - Private Retreat

Lake-front retreat w/ unbelievable sunsets, swimming & kayaking, tucked in between the Cliffs & the Reserve, 30 miles west of Greenville. Private park-like setting for a couples getaway. Updated one-bedroom small cottage w/ living room, kitchen, bath, laundry, AC/heat. The entire property is included w/ your cottage rental; 1.1 acres, 800 ft of lake shoreline, a dock, a pier, a sunset deck, a social pavilion, waterfront hot-tub. It is a private lake experience; nothing really compares - unique!

Top guest favorite
A porch swing is set on a wooden deck, adorned with plush cushions featuring intricate patterns. Lush greenery and colorful flowers are visible in the background, adding vibrancy to the serene outdoor setting.
Guesthouse in Six Mile
4.97 out of 5 average rating, 173 reviews

Your Charming Country Cottage

Whether you need a country getaway or a place to lay your head after a football game, our cottage in the foothills of upstate SC is the perfect spot for both. You’ll find us tucked away just outside the quaint little town of Six Mile, 10 miles north of Clemson University and in close proximity to 3 of the upstate's favorite lakes: Lake Keowee, Lake Jocassee and Lake Hartwell. Here you’ll enjoy the serenity of country life without feeling “too far out" or away from all the upstate has to offer.

Superhost
The serene lake landscape is painted with vibrant colors at sunset, featuring hues of orange, pink, and purple. The calm water reflects the dramatic sky and surrounding trees, creating a peaceful atmosphere. A dock is visible at the edge of the frame.
Cottage in Townville
4.84 out of 5 average rating, 151 reviews

Waterfront cottage w/deep dock 17 miles to Clemson

Welcome to the Queen of Harts, our 2BR/1BA, waterfront cottage on Lake Hartwell w/private, deep water dock. The house is located on a quite street 25 min to Clemson. Interior has been remodeled including farmhouse kitchen sink, butcher block countertops, dishwasher, large bathroom, washer/dryer, and new furnishings. Enjoy beautiful sunsets on the dock or explore the cove on stand-up paddle boards included with rental. Other amenities include wi-fi, 55" Smart TV, charcoal grill, and fire pit.

Top guest favorite
A spacious outdoor dining area is visible through a large hinge window. The wooden table is surrounded by four folding chairs, with a scenic view of the lake and trees in the background. Sunlight filters through, enhancing the seamless indoor-outdoor connection.
Cottage in Seneca
4.99 out of 5 average rating, 115 reviews

Destination Keowee

A rustic industrial style Lake Keowee lakefront escape that places you right on a panoramic point in a private cove. Welcome the outdoors in with the 6ft kitchen hinge bar window to the upper deck or enjoy the 6-seat hot tub on lower deck. Deep water dock tie off space is available. Guests enjoy the use of 2 standup paddle boards, and lakeside fire pit (guest provide firewood). Great cove sunsets! 15 minutes to Clemson and 1 min Lighthouse Restaurant. Please read all details prior to booking!

Superhost
A geodesic dome is illuminated from within, set against a backdrop of trees. An adjacent wooden structure features outdoor seating under string lights, creating a welcoming atmosphere for relaxation. The natural environment is highlighted, emphasizing the dome's unique design.
Dome in Salem
4.89 out of 5 average rating, 353 reviews

G.O.A.T. Geodome: Farm Animals, Hot Tub, Zip Line

Glamping: where luxury meets the outdoors. This geodesic structure offers a rare opportunity to experience the outdoors without the elements. Complete with kitchen, AC & heat, dual control heated mattress pad, fully functioning bathroom, and sunrise views over the pasture. Whether you are looking to relax and enjoy feeding the farm animals, have an adventure riding the zip line, or indulge in a romantic evening sipping wine in the hot tub under the stars, you will leave with lasting memories.

Top guest favorite
A treehouse surrounded by trees glows gently with warm lights in the evening. Two Adirondack chairs are positioned around a fire pit, with a small table nearby. The forest setting offers a calm and inviting atmosphere for outdoor relaxation.
Treehouse in Mountain Rest
5 out of 5 average rating, 459 reviews

THE BELLA LUNA Romantic Treehouse - Outdoor Shower

This is the perfect ROMANTIC ESCAPE! Located in the Sumter National Forest the Bella Luna is just 5 minutes from Stumphouse Tunnel, Issaqueena Falls, Yellow Branch Falls hiking trail, and Stumphouse Mountain Bike Park and within an hour of Clemson, Lake Jocassee and Clayton, GA. Our romantic retreat features carefully curated vintage furnishings, an outdoor shower, napping net, relaxing seating areas and an outdoor fire pit stocked with firewood and a S’mores kit! We can't wait to host you!

Guest favorite
A cozy living area features a stone fireplace flanked by windows, allowing natural light to illuminate the space. A comfortable sofa is arranged around a small table, accompanied by a chair. A TV is mounted above the fireplace for entertainment.
Condo in Salem
4.97 out of 5 average rating, 144 reviews

Beautiful Lake Keowee Condo with great Amenities

"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"

Top guest favorite
A charming cabin is nestled among tall trees, accessed by a stone path. Warm string lights adorn the porch area, creating a welcoming glow. Fallen leaves blanket the ground, complementing the natural surroundings and inviting a sense of tranquility.
Cabin in Pickens
4.98 out of 5 average rating, 255 reviews

The Romantic Greystone Cottage

Follow the enchanting stone path to a private getaway where romance and connection await. Enjoy the ambiance of the starlit sky while cuddled up on the hammock or around the fire. Cozy up on the king-size bed and relish every moment of your stay. Indulge in a bottle of wine and relax by soaking in the luxurious claw-foot tub. Wake up to the tranquil sounds of the forest, savoring the morning with coffee on the porch. Escape the everyday and embrace what matters most at The Greystone Cottage.

Guest favorite
Home in Six Mile
4.83 out of 5 average rating, 259 reviews

House on Lake Keowee swim beach in cove w/ Dock

This two story home is located at the end of a very quiet cove with plenty of water. The beach has a fresh 6 inches of sand installed for the lake season. The walk to the lake is very short on an almost flat surface. The home will accommodate a family up to six people. The house has two floors. The main floor has a large living room with plenty of comfortable seating and satellite TV service provided. The entire main floor has hard woods along with the Master Bed Room and bed room #2.

Guest favorite
Home in Westminster
4.94 out of 5 average rating, 293 reviews

Waterfall Views, Lake Hartwell, Highland Architect

Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Top guest favorite
The charming cabin exterior is surrounded by lush greenery and mature trees. A welcoming front porch adorned with decorative plants leads to the entrance. An American flag hangs gracefully by the front door, and a paved driveway extends towards the cabin.
Cabin in Seneca
4.96 out of 5 average rating, 129 reviews

Lake Keowee Cabin: Peaceful and Bright

Welcome to Lizard Lodge. Relax in this quaint lake cabin with a mountain home vibe nestled in Northern Seneca on Lake Keowee. Enjoy the serenity of a beautifully modern 3-bedroom, 2.5 bath vacation cabin in a quiet gated cul-de-sac with scenic surroundings. On early mornings you can spot wildlife including deer and wild turkeys. Excellent location on the lake a few hundred feet away from a boat ramp. Come to relax, have fun on the lake or even enjoy a romantic escape.

Top guest favorite
A modern cottage features a spacious covered porch with string lights, surrounded by a lush green lawn. Large glass doors invite natural light into the interior, while tall trees provide shade in the background against a colorful sunset sky.
Cottage in Anderson
4.96 out of 5 average rating, 227 reviews

Lakefront dock *hot tub* Anderson/Clemson king bed

Relax & enjoy the beautiful views of lake Hartwell from the front porch daybed swing, hot tub, or private dock. Sleep in a king size bed wrapped in cool cotton linens, a towel warmer, soaking tub with TV, & a breville espresso maker. Located w/i 10 minutes of many restaurants. Less than 20 min. to downtown Anderson Pendleton or Clemson. This prime location on lake Hartwell is a 10 minute boat ride to Portman Shoals Marina, the Galley restaurant, & Green Pond Landing.

Popular amenities for Lake Keowee vacation rentals

Frequently Asked Questions

  • Where is Lake Keowee located?

    Lake Keowee is in northwestern South Carolina, surrounded by the foothills of the Blue Ridge Mountains. The lake is near the towns of Seneca and Salem, giving visitors access to small-town atmospheres alongside natural scenery.

  • When is the best time to visit Lake Keowee?

    Late spring through early fall is often recommended for Lake Keowee, as temperatures typically range from 65–90°F (18–32°C) with comfortable water conditions. Mild autumn weather invites changing foliage, while summer has warm afternoons for swimming and boating.

  • What are some things to do near Lake Keowee?

    Around Lake Keowee, you can explore hiking trails, enjoy boating or fishing, and visit state parks with picnic spots and scenic overlooks. The area also has local markets, golf courses, and spaces for water sports and kayaking.

  • How is the weather near Lake Keowee?

    Lake Keowee has mild winters, with January lows near 33°F (1°C) and highs around 53°F (12°C), while summers are warm and humid, reaching up to 90°F (32°C) in July. Rain is spread throughout the year, with slightly drier months in early fall.

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