
House vacation rentals in Grimes
Find and book unique houses on Airbnb
Top-rated house rentals in Grimes
Guests agree: these houses are highly rated for location, cleanliness, and more.

MidCentury, technicolor Ranch w/yard, w+d, parking
- Ranch home in Des Moines' friendly Beaverdale neighborhood - Steps from grocery store, ice cream shop+dining - Blocks to more dining+shops - Less than 5 minutes from Drake University - Around 10 minutes from downtown, Des Moines, Arts Center, parks - Easy access within 15 minutes to suburbs - 1000+ feet with open living, dining and kitchen, 2 beds, 1 bath, laundry and on-site parking - Outdoor front porch, back patio+fire pit - Perfect for a family or two couples ***Send your special requests!

Sleeps 16/GameRM/Pool/Hot tub/Large backyard/Pets
Gather your group in this spacious 5BR, 3BA retreat made for connection and fun. After a day exploring, come back to the pool, hot tub, and sunroom dining. Inside, unwind in two cozy lounges or spark friendly competition in the arcade and game-filled garage. With room for 16, this home isn’t just a stay—it’s where family and friends celebrate, play, and make lasting memories together. Close to: 🏴5 mins to Get Air Trampoline Park ⛳ 10 minutes to Topgolf 🌆 20 minutes to Downtown Des Moines

Heartland BNB~Hot Tub~Sauna~fire table~2 kings
Comfort and convenience await your arrival at this centrally located home just minutes from downtown Des Moines and next to Ingersoll nightlife. This home has been newly renovated and designed for traveling families and business professionals alike. Soak away the stress in the 7 person hot tub or sweat it all out in the outdoor 5 person sauna! Grill on the patio and relax by the fire, before going to sleep in 2 very stylish and comfortable king bedrooms located on the main floor. Book Now!!

Gray Manor
Your family will be close to everything when you stay at this centrally-located home in West Des Moines, just off I-35. A bike trail leading to parks and local businesses runs through the backyard. With comfortable furnishings, and spacious rooms it's perfect for gathering with friends and family. Mere minutes from West Glen Town Center or Jordan Creek Mall! During your stay you'll have access to 4 bedrooms and 4 baths, a fully equipped kitchen, spacious living rooms, and large deck with grill.

Maple Street Hideaway
Large 2-bedroom main level living, fenced backyard, and deck. We are pet friendly with no additional fees (although we do expect guest to pick up after them). Plenty of parking on property. Small town Iowa, easy access to WDSM/Waukee/Grimes/Johnston/Adel. Less than a 20 min. drive to an abundance of restaurants, shops, and attractions - not including the great places to eat/visit in town. Beautiful, quiet, tree lined street. Google Dallas Center to see all this Quietly Progressive town offers.

Effortless Landing near Airport!
Welcome to the Effortless Landing! Our super clean and comfy, Boho style retreat. Private keyless entry with off street parking. Enjoy a queen bed, additional pull out queen bed in the couch, great local coffee, & all the amenities like fiber wifi, TV, full kitchen, & laundry. Add that to the wonderful surroundings of the city of Des Moines, in a quiet, centrally located neighborhood. Conveniently located 4 minutes from the Des Moines International Airport, & 7 minutes to Downtown Des Moines!

Charming & Cozy Beaverdale 4BR/2BA In Central DSM
Experience the charm of Des Moines in this beautiful 4-bedroom, 2-bathroom home located in the vibrant Beaverdale neighborhood. > SAFE & Family friendly neighborhood > 1/2 block to grocery store > Minutes from Drake University & 7 minutes to downtown > 4 separate bedrooms > Pet Friendly! (w/ fee) > Long driveway for parking w/ under home garage in back > High Speed WiFi > Smart TV's in all rooms > Near restaurants and shopping > BBQ Grill > 1 King, 2 queen & 1 full bed > Full bath & 1/2 bath

Peaceful Setting & Modern Style
Escape the hustle and bustle of the city and retreat to your own private oasis with this charming 2 Bedroom Airbnb. The house provides present-day amenities while still honoring the original 1930s character. You’ll enjoy a new and sparkling clean kitchen, complete with all the appliances and utensils you need. The bathroom, laundry, dining room, reading nook and living room have all been beautifully updated as well, ensuring that you'll feel right at home from the moment you arrive.

The Carol Anne-Charming 2bd/2ba Victorian near DT!
This Victorian-era duplex is the perfect mix of Victorian and modern for all the comforts of home. Perfect for quick or extended trips. Location can't be beat: Walking distance to Drake University. Minutes by car to downtown, hospitals, Ingersoll district and proximity to I-235 gets you anywhere in the city. Off street parking/electronic locks make check-in a easy. 2 large bedrooms w/queen beds, 2 bathrooms, kitchen, laundry, closets, and more making it ideal for multiple guests!

Newly Remodeled Home with Walk-In Shower
My home is located in a safe and quiet neighborhood of Ankeny with a 16 min. drive to downtown Des Moines and Wells Fargo Arena. The high trestle trail is about 8 blocks away with a nice park 1 block away. The highlight of my home is the newly remodeled bedrooms and bathroom. There are queen beds in each of the bedrooms. The guest bed is brand new. The living room has a 55” LG OLED 4k TV with a PlayStation 5. I have high-speed cable internet with cable through slingTV.

Suburban Oasis with Hot Tub
Sleeping 12 people, 4 bedrooms, 7 beds, 3.5 bathrooms, this comfortable suburban home offers a new hot tub with Bluetooth speakers, and fenced in yard. Walk out basement includes an air hockey table, day bed, recliners, and separate kitchen area with new mini fridge to relax day to night with the family. Fiber WiFi available and smart TVs in the living areas to enjoy any entertainment. This home is the ideal place to gather.

Restored Victorian, Walk & Bike
Completely restored Victorian home that is walking and biking distance to the East Village, Civic Center, Wells Fargo, world-renowned skate park, and the Iowa Capitol! Bring your bike and enjoys the trails (and indoor bike parking). Walk to a concert at Wells Fargo or a show at the Civic Center. We are dedicated to making your stay simple and easy. This house is special to us, and we want to share it with you!
Popular amenities for Grimes house rentals
House rentals with a pool

New Arrival Peaceful Comfort Calm & Private

Comfortable and Spacious Five Bedroom Home

Urbandale Oasis

New Remodel! Family Fun House

Ankeny Stay | Gym | Game Room | Spa | BBQ | I-35

Summer House DSM

Urban Oasis with Pool & Hot Tub

Grimes Getaway with pool
Weekly house rentals

Retro 2 Bedroom APT in Waukee, IA

Stylish Beaverdale 2 Bedroom - King and Queen Beds

Fresh Remodel! Whole House Getaway Near DSM!

Stunning Suburban Home in Quiet Neighborhood

Beautiful comfy five bedroom home sleeps 13

Entire Bungalow in Walkable Neighborhood!

Sleeps 10, Fire pit, Outdoor Eating & Grill, Gym

Spacious tranquil 4BR Home - family entertainment
Private house rentals

Charming home by Drake/Downtown!

Cozy Cute Bungalow

The Draper-MCM Spacious Ranch minutes to it all

Modern Comfort in Ankeny

CozyHouse w/ HotTub, Sleeps 8,3BR,2BA,2LvngRms

Rest At Ease in Ankeny

Once Upon A Stay

Mandi’s Tiny House: A Hidden Gem
When is the best time to visit Grimes?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ621 | ﺩ.ﺇ657 | ﺩ.ﺇ610 | ﺩ.ﺇ661 | ﺩ.ﺇ716 | ﺩ.ﺇ738 | ﺩ.ﺇ742 | ﺩ.ﺇ738 | ﺩ.ﺇ617 | ﺩ.ﺇ731 | ﺩ.ﺇ746 | ﺩ.ﺇ610 |
| Avg. temp | -5°C | -3°C | 4°C | 11°C | 17°C | 22°C | 24°C | 23°C | 19°C | 12°C | 4°C | -2°C |
Quick stats about house rentals in Grimes

Total vacation rentals
Explore 40 vacation rentals in Grimes

Nightly prices starting at
Grimes vacation rentals start at ﺩ.ﺇ73 per night before taxes and fees

Verified guest reviews
Over 1,150 verified reviews to help you choose

Family-friendly vacation rentals
30 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
40 of Grimes vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Grimes rentals

4.8 Average rating
Grimes stays are highly rated by guests—averaging 4.8 out of 5!
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