Vacation rentals with a patio in Florence County

Crystal Place Near MUSC and Mcleod Hospital

2-bedroom, 1-bath cozy home located in the heart of Florence, SC. This fully furnished home comes with two queen beds,one full bathroom, washer/dryer laundry, full kitchen, and a smart TV. Located 3.8 miles from McLeod Health and 1.0 miles from MUSC Hospital.Ring security camera on site monitor driveway actively recording visual and audio 24/7 during your stay. Potential for traffic and neighborhood noise.

Renovated 2 BR/2 B Townhouse Cozy & Clean

Keep it simple at this peaceful, centrally-located, and renovated townhouse close by I-95 and I-20 and within 15 mins. to the Florence Center, downtown Florence, many restaurants, and McLeod and MUSC Florence. House is located in a safe neighborhood with 2 queen beds and 1 sofa bed in the living room. Enjoy being outdoors? Relax outdoors on your own private patio, go on a walk around the neighborhood, or go on an adventure. The Rail Trail & Ebenezer Park are minutes away. Utilities included.

Blu Grace Farm Apartment

Our barndo is located on our quaint 10 acre farm. The barn sits in the center of two pastures overseeing highland cows, horses, alpaca, donkeys, sheep and ducks. A cup of coffee, the sound of the rooster crowing while rocking under the awning is an experience in itself. Pet and feed the livestock during your visit. We are conveniently located near several wedding venues in historic Marion county and just an hour from Myrtle Beach. This is a rustic and peaceful farm experience you won’t forget.

Cozy Florence Retreat Near Civic Center & I-95

Welcome to your Florence getaway! This bright, modern, and cozy Welcome to your Florence getaway! This bright, modern, and cozy home is perfectly located near I-95, Downtown Florence, the Florence Civic Center, and Darlington Raceway. Enjoy shopping and dining at nearby Buc-ee's, or take a short 1.5-hour drive to Myrtle Beach. The home features a fully equipped kitchen, comfortable bedrooms, and convenient parking—ideal for road trips, events, family stays, or a relaxing Southern escape.

Collins Quarters

In the middle of town, this unique place has a style all on its own. Inspired by Mountain Bungalows and Spanish accents, this one of a kind home sits directly beside MUSC in Florence SC. Close to everything you can possibly need, amenities include: 1 King bed, 1 Queen bed, 1 twin bed, 1 Full Size sofa bed, a full kitchen with living room and dining area, outdoor shower, and a nice sizable front porch to sit and sip your morning coffee looking over a beautiful landscaped front yard.

Governor's Square at Coventry @ I-20/I-95

This private, cozy two bedroom 1 1⁄2 bath condo has recently been renovated and is discounted for longer stays. The condo includes 2 bedrooms. It's located among quiet neighborhoods for peaceful walks or for sitting outside on the private patio. Within five minutes you’ll find access to I-20 & I-95, restaurants, malls, civic center, movie theater, Florence rail trail and parks, golfing, tennis, soccer and more. Highway 76 is two miles away and takes you directly to Myrtle Beach.

Enchanting Treehouse with Modern Amenities

Perched on 20 acres along Catfish Creek, this enchanting tree house allows you to appreciate nature from a birds eye view. Whether it’s kayaking, canoeing, or exploring along the creek; relaxing in the hammocks and swings; engaging in a board game; or roasting marshmallows at the fire pit, Amenities include a full kitchen with full bath, outdoor shower, booth seating in dining table for up to 8, 2 bunk beds and loft style sleeping.

Modern 3BR/2BA Home in Lake City – Quiet & Central

Modern, clean 3BR/2BA home in quiet Lake City neighborhood—just minutes from shops, dining, and downtown. Each bedroom has a comfy bed, fresh linens, and a flat-screen TV. Kitchen includes basic cookware, utensils, and a Keurig with coffee pods. Enjoy free Wi-Fi, washer/dryer, and ample parking. Perfect for business, family, or a relaxing getaway. Centrally located and fully equipped for a comfortable stay!

Creekside Cottage - 4 Bedrooms

Enjoy your staying on this newly renovated Pet friendly house. Treat yourself with a cup of coffee at the deck while you watch your furry baby play in the big fenced backyard. This house is centrally located in Florence. Only minutes from downtown Florence, Grocery stores, Pharmacies, Restaurants, MUSC Hospital, McLeod Hospital. This house has two king bed bedrooms and two Queen bed bedrooms.

DOWNTOWN Boho & Vibrant Cottage on Park

This sweet and unique boho home is set in a quiet neighborhood with a lovely porch. It is very close to downtown as well as the main hospital. It is a perfect, central location for those who desire to experience historic Florence or those needing a peaceful and calm place to stay close to the hospital. Come enjoy yourself and relax at our wonderfully located getaway and home away from home.

Delightful 3 Bedroom Home in the heart of Marion

Be at home with this delightful 3 bedroom country home, located in the heart of Marion, just a short walk away from Main Street. Only 1 hour away from Myrtle Beach, 35 minutes from Florence and more! Home is a 2 story, with 1/2 bath on bottom floor. 3 bedrooms and 1 full bath on top floor.

Rutt Farm Vineyard Plug into Simple

Enjoy a get-away that combines the beauty of southern nature with the charm of vintage-simplicity. Wake up to the sunrise over open vineyard, farm-fresh eggs, and a sample of home-harvested honey from our beehives. Break away from the noise. Plug into simple. 15 minutes from I-95 and I-20