Vacation rentals in East Prairie

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Top-rated vacation rentals in East Prairie

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
The entryway of the cabin is illuminated at night, featuring a stone facade and a welcoming front door adorned with a wreath. A grill is situated beside the door, and soft landscaping is visible on the side.
Cabin in Paducah
4.99 out of 5 average rating, 158 reviews

Cozy Hideaway King Bed & FirePit

Cute Cabin on 30 acres with a Pond, Fire Pit and a covered porch with beautiful view. Located 1 mile from the I-24 and minutes from town. The cabin consists of one bedroom with King Size Bed, Bathroom, Kitchenette (Countertop Double Burner & Ninja Oven/Toaster), Living Room and washer & dryer. Sectional couch with recliners. Comfortable Air Mattress for Living Room if you need to sleep 4 guests. Flat Screen TV's in the Living Room & Bedroom. Pet Mini Cows Dozer & Daisy & owners live on site.

Guest favorite
Dome in Brookport
4.94 out of 5 average rating, 32 reviews

Glamping Double Domes on Private Lake & Hot Tub!

Adventure meets comfort at the Space Cowboy Lake Domes — the ultimate glamping experience where rustic frontier charm collides with sleek modern design. This unique double-dome retreat features a full kitchen, bathroom, and space for up to four guests across two connected domes — one with a cozy living area and sleeper sofa, the other with a private queen bedroom. Step outside to your expansive lakefront deck with a hot tub, fire pit, grill, outdoor shower, and private lake access and kayaks.

Top guest favorite
Home in Piggott
5 out of 5 average rating, 15 reviews

Secluded Shop-House Retreat/Walk to Heritage Park!

Experience the perfect blend of wooded privacy at our unique "Shop-House". Tucked away on a dead-end road, this 2-bed, 1-bath retreat is steps from Heritage Park, minutes from the Hemingway-Pfeiffer Museum, And located great for duck hunting. Enjoy the full-size pool table and ping pong, dedicated coffee station or fire up the propane grill amidst the peaceful, wooded surroundings. With high-speed Wi-Fi and plenty of privacy, it’s the ultimate secluded base for exploring the best of Piggott!

Guest favorite
The custom-built treehouse is elevated on stilts, surrounded by greenery. A spacious deck features a railing, offering access to the entrance. Steps lead to the ground below, while large glass doors enhance the connection to nature.
Treehouse in Cape Girardeau
5 out of 5 average rating, 210 reviews

Twisted Sassafras Treehouse

A custom-built treehouse located on 10 acres with a water view that you can take in from the hot tub on the deck! It is nestled high in the trees and is the perfect romantic getaway for two! Feel like you are away from it all without being away from it all! This treehouse is located on a county road just minutes from Cape Girardeau. Enjoy catch and release fishing on site, local wineries, shopping in historic downtown Cape Girardeau, local restaurants, gambling, historical sites & more!

Superhost
A modern kitchen features rich dark cabinetry and a light granite countertop. Stainless steel appliances are present, including a double oven and a range hood. A glass pitcher and several clear glasses are arranged on the counter, accompanied by a striped mat underfoot.
Home in New Madrid
4.55 out of 5 average rating, 11 reviews

Rivertown Getaway

Great location in the middle of town. Easy walk to the downtown area that offers great history on area with a museum & historic one room schoolhouse, take a walk along the beautiful Mississippi River, check out Veterans Park, etc., so much do to and see! This home can sleep 4 comfortably and accommodate 2 more guest with a blowup air mattress that is on site. Inside you will find new appliances, bedding, and linens. The outside is a work in progress! No smoking or pets allowed.

Top guest favorite
A modern farmhouse is depicted at sunset, featuring a welcoming entrance with a covered porch. A stone pathway leads to the front door, bordered by a grassy lawn that extends to fields and trees in the background.
Barn in Cape Girardeau
4.95 out of 5 average rating, 277 reviews

Under the Stars - Farmhouse

Enjoy the tranquility of this modern farmhouse charmer! Custom built minutes from downtown Cape. Relax outside around the fire pit, roast marshmallows and watch the sunset. Finish the night with a long soak in the hot tub. Start the morning on the front porch rocking chairs and take in a sunrise. Open concept, fully equipped kitchen, 3 Bd. including King master/full bath, 2 Queens with full guest bath. Near Trail of Tears and walking distance to classic dive bar/burger joint

Top guest favorite
A modern tiny home features a welcoming entrance, with a wooden porch and steps leading up to the front door. Rocking chairs provide a cozy seating area, surrounded by a gravel pathway and green lawn. Trees are seen in the background, adding to the serene setting.
Tiny home in Bardwell
4.93 out of 5 average rating, 70 reviews

The Roost - Pets friendly

Welcome to The Roost, a cozy, modern tiny home in rural western Kentucky. With two lofts, a bedroom, full kitchen, washer/dryer, and space to sleep five, it’s perfect for a peaceful getaway. The property is home to our 4 off leash dogs who will greet you upon arrival. We ask all other animals are dog friendly. Enjoy sunsets, stocked ponds, wildlife, outdoor dining, and a fire pit. Named after The Hickory Chicken—Southern slang for morel mushrooms—this hidden gem is worth the search

Top guest favorite
Home in West Paducah
5 out of 5 average rating, 27 reviews

Modern Luxury Cabin, Fireplaces, Hot Tub Paducah

Shepherd’s Lantern Acres offers an unparalleled luxury retreat experience, featuring two cabins that seamlessly blend modern comfort with breathtaking natural beauty. Your cabin features unobstructed views of over 2 acres of seasonal wildflower meadows and pristine nature. Dogs are also welcome to enjoy their very own dog spa! With a beautiful master suite, well-appointed kitchen, and in unit laundry, we have ensured that all the comforts of home are at your fingertips.

Guest favorite
Home in New Madrid
4.93 out of 5 average rating, 14 reviews

Family Home near the MS River with a toy Room

The whole group will enjoy easy access to everything from this centrally located place. 3 blocks from the New Madrid boat ramp / levee. Less than 5 miles from HWY 55. Large family style home - on the first level - living room, dining room, kitchen, laundry room, guest bathroom, main bedroom and main bathroom. The upstairs has 2 bedrooms and a toy room with another full bathroom upstairs.

Top guest favorite
Home in Clinton
4.99 out of 5 average rating, 208 reviews

The Peery House at Springhill Farms

The Peery House is our family home-place, built circa 1900, transformed into a quaint Airbnb. It is located on our farm, Springhill Family Farms in Western KY and is a great place for someone looking to get away from the busyness of life, looking for rest and relaxation or just looking for a unique, little farmhouse while passing through the area.

Top guest favorite
Home in Hornbeak
4.99 out of 5 average rating, 153 reviews

THE DREAMCATCHER

Beautiful brick home with lake view and access to Reelfoot Lake (no ramp), paved drive with ample parking for boat / trailer, back deck with table and chairs, open space kitchen and den, perfect for group fishing trip, hunting trip, or just sight seeing, (area known for its large population of eagles), quiet neighborhood, peaceful place to stay.

Top guest favorite
A comfortable living area features a dark sofa adorned with a seasonal pillow. A round chandelier hangs above, providing soft lighting. A coffee table rests in front of the couch, surrounded by side tables with lamps. Wall art depicting winter scenes is displayed above the sofa.
Cottage in Paducah
4.99 out of 5 average rating, 707 reviews

Copper Creek Cottage in the country close to city

Welcome to Copper Creek Cottage. We are located in the country but minutes away from downtown Paducah, and the mall area. We are 2.5 miles from I-24. Our cottage sleeps 4. (Queen bed & full pull-out sofa). The cottage is great for a couple's weekend, girls' trip or any occasion. The nightly price will be reduced for longer stays.

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