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Vacation rentals in Du Bois

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Top-rated vacation rentals in Du Bois

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A living area features hardwood floors and leather furniture, including a spacious sectional and reclining chair. A coffee table with decorative elements is centered in the room. Large windows allow natural light to fill the space, with neutral walls and a TV mounted on the far wall.
Home in Waltonville
5 out of 5 average rating, 40 reviews

House near Rend Lake with large patio

With less than 5 miles to the nearest boat ramp, this home is great for those who want to fish on Rend Lake (our area is great for hunting, too). Hardwood floors, porcelain tile (including a heated bathroom floor), leather furniture and a gas fireplace make the inside clean and relaxing. A spacious paved patio with plenty of seating and a charcoal grill make the outside just as enjoyable! Single night stays during peak season can be requested on a case by case basis. Just message for details.

Top guest favorite
An outdoor fire pit area features several metal chairs arranged around a gravel circle. A cabin stands in the background, surrounded by trees shedding autumn leaves. Clear blue skies above provide ample natural light.
Cabin in Salem
4.98 out of 5 average rating, 110 reviews

Spillway Cabin’s (Brand new!) West Cabin

The Spillway Cabins are new construction with new everything! Our little slice of heaven is yours to explore and enjoy. Each cabin(west and east) have 2 br/2bth, hot tub, gas grill, Starlink internet, large flatscreen TV’s, fully stocked kitchen, and fire pits! From the south side of the cabins you will find a pathway that will take you through our 7 acres of woods and down to a lakeside pergola that has comfortable outdoor furniture, a bar, and view of our beloved Centralia Lake and spillway.

Guest favorite
A cozy bedroom is featured with warm wood paneling and a metal ceiling. A spacious bed with soft linens is positioned near a window. A comfortable armchair and a nightstand with a lamp are included, contributing to the inviting ambience.
Tiny home in Whittington
4.91 out of 5 average rating, 325 reviews

Tiny Home of Whittington

This cozy tiny home is located a little over one mile off of Interstate 57 and within two miles of Rend Lake. Whether traveling through and needing an easy one night stay or a weekend getaway, this is the place for you. Located in the quiet village of Whittington, the property has great access to the area while providing a peaceful stay on the edge of the country. Our property has multiple rental buildings, but there is plenty of parking space for anyone traveling with a pickup and trailer.

Top guest favorite
A modern kitchen area features sleek white cabinetry and a contrasting black refrigerator. Countertops offer ample space, while a central island with green bar stools invites casual dining. Soft lighting enhances the contemporary design, and exposed brick adds a touch of historic charm.
Apartment in Du Quoin
4.98 out of 5 average rating, 57 reviews

Loft Apartment On Main - Sleeps 4

Experience the beauty of downtown Du Quoin at our stunning historic loft apartment. Curated with brand new construction; this space boasts stylish design elements combined with modern amenities to create a truly unique stay. You'll love the large windows, high ceilings, and extra space. This loft boasts a prime location overlooking Main Street. Walking distance: St. Nicholas Hotel Brewery, Biancos ice cream shop, Alongis Italian restaurant, Marks Bakery and many small town shops.

Top guest favorite
The treehouse structure is elevated, supported by stilts, with large windows that reflect the surrounding greenery. The exterior features a combination of wood finishes, and warm lighting casts a welcoming glow in the evening. The pathway leads through the natural landscape to the entrance.
Treehouse in Perryville
5 out of 5 average rating, 700 reviews

Private Treehouse Retreat | Hot tub

The TreeLoft is the first of two treehouses at BaseCamp—designed for cozy seclusion, romance, and rest. Nestled in a private forest just 1 hour from St. Louis, it blends upscale comfort with immersive nature, while still being 20–35 minutes from hiking, wineries, and dining. ✨Our NEW treehouse, The TreeRise, offers an even more elevated, spacious experience at BaseCamp. Perfect for romantic getaways, anniversaries, personal retreats, and intentional escapes to unplug and reconnect.

Top guest favorite
A cozy bedroom features a spacious bed adorned with a white coverlet and decorative pillows. Natural light enters through two diamond-patterned windows, illuminating the soft green walls and wooden accents. A side table and floor lamp add functionality, while two folding luggage racks are neatly arranged in the corner.
Apartment in Du Quoin
4.98 out of 5 average rating, 62 reviews

Unique apartment in downtown DuQuoin Room #201

This restored Chapel is close to everything. Located right at the park, walking distance to Main Street. Each apartment is self contained with key-less entry. Perfect for a fun getaway or extended stays for work contracts. Full kitchen. A few trains rumble by but with our sound machine this downtown apartment becomes your sleep sanctuary. Come and enjoy a private apartment in this restored 1920s church. 25 minutes to Carbondale, 1 hr 20 minutes to Belleville, 45 minutes to Marion

Top guest favorite
A comfortable living area features a stone fireplace beneath a mounted television. A wooden coffee table is surrounded by a brown leather sofa and a chair. Scenic wall art is displayed above the sofa, while natural light enters through a nearby window.
Cabin in Makanda
4.99 out of 5 average rating, 172 reviews

Hygge Log Cabin: HotTub & Hiking

Hi, hello, welcome! We are excited to have the opportunity to host you for your relaxing trip or jam packed adventure. Our local area has many hiking opportunities to explore, the Southern Illinois Wine Trail surrounds us, and the back roads have country views that are breathtaking. Our cabin will be waiting for your arrival or return, well equipped with a 55" TV above the gas fireplace, a comfortable King size bed, and an amazing back porch with a Weber Grill and huge hot tub.

Top guest favorite
The treehouse is elevated on wooden stilts, surrounded by lush greenery. A wooden deck with a railing extends from the entrance, creating a welcoming outdoor space. Large windows brighten the upper level, while a sun art piece adorns the side of the structure.
Treehouse in Makanda
4.96 out of 5 average rating, 435 reviews

Panthers Inn Treehouse

Come nestle amongst the leaves at Panthers Inn Treehouse. This secluded, well equipped, elevated cabin has the perfect combination of natural beauty and artful luxury. Isolated yet conveniently located 2 minutes from Blue Sky and Feather Hill wineries, within 5 minutes of Panthers Den hiking trail and the Shawnee Hills canopy tour and only 10 min from I-57 exit 40. Panthers Inn is the perfect starting and ending point to your Shawnee Hills Wine Country vacation!

Guest favorite
The exterior of the home is visible, set within a spacious green yard. A garage is positioned to one side, with a driveway leading up to the entrance. Surrounding trees provide a natural backdrop, enhancing the serene country setting.
Home in Ewing
4.9 out of 5 average rating, 151 reviews

"Quiet And Secluded Country Setting" BIG OAKS

We have a 2000 sq. ft. home located on 3 acres in a very country setting. It has 3 bedrooms, 2 baths, master bed room has queen size bed, second bedroom has full size bed and third bedroom has 2 twin beds. Large master bath with large soaking tub and shower. Spacious kitchen is set up to cook if you like, . The back porch over looks the woods and fields with lots of deer siting. Our location is very quit and peaceful. also there is a garage you have access to.

Superhost
Two elegant wine glasses are placed on a wooden railing, reflecting sunlight. The glasses contain deep red wine, while a lush green field and sparse trees create a serene backdrop in the distance.
Home in Tamaroa
4.87 out of 5 average rating, 93 reviews

The Hideaway

Nature Lovers Paradise-- Disconnect from your devices and connect with nature in this clean, spacious hideaway. If you crave hiking or walking, sitting by the pond, reading on the porch or traveling to nearby wineries and shopping at all the local boutique and antique stores, this is the perfect spot for you to recharge and enjoy. Close to numerous restaurants, and local and state parks.

Guest favorite
Loft in Mount Vernon
4.96 out of 5 average rating, 83 reviews

Guests rave: Peaceful & Clean. Comfortable Bed

Peaceful, secluded loft. Safely surrounded by kind neighbors. CLEAN!! WIFI. Smoking and pets allowed outside only. Upstairs with queen bed & sofa bed. Sleeps 2-3. Balcony. Full kitchen. Coffee. Washer/dryer. Pond for fishing, trail in woods. 5 miles from interstate, shopping & restaurants. 20 miles from Rend Lake. Check in 3pm Check out 10am

Superhost
A modern kitchen area features stainless steel appliances against exposed brick walls, creating a warm ambiance. A wooden island with two stools centers the space, while cabinetry provides storage. Natural light illuminates the area, highlighting the blend of rustic and contemporary elements.
Apartment in Du Quoin
4.91 out of 5 average rating, 146 reviews

30 West·The Den ·Downtown Hideaway near Fairground

Welcome to 30 West · The Den, a modern downtown hideaway in the heart of Du Quoin. Just minutes from the State Fairgrounds, local restaurants, and the Shawnee Wine Trail, this cozy retreat is perfect for couples, solo travelers, or remote workers. With thoughtful touches, fast Wi-Fi, and a warm atmosphere, you’ll feel right at home.

Popular amenities for Du Bois vacation rentals

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