House vacation rentals in Downtown, Jacksonville

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Top-rated house rentals in Downtown, Jacksonville

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite

Home in San Marco

4.98 out of 5 average rating, 213 reviews

Luxurious Craftsman in Historic San Marco

Never Drive Again! Immaculately renovated San Marco Bungalow, just a minute from excellent restaurants, retail, entertainment, hospitals & easy transit (via San Marco's FREE Beachside Buggy App) to everything else. Features include an inviting front porch, interior foyer, charming living room w/gas fireplace, new kitchen w/SS and granite, indoor laundry, historic architectural features, and private backyard w/ sitting area, fire pit, games & BBQ! Incredible location with unmatched walkability!

Oct 13 – 20

ﺩ.ﺇ578 per night

Guest favorite

Home in Jacksonville

5.0 out of 5 average rating, 209 reviews

King bed home w/bikes on the best Riverside block!

This super fun house is perfectly located in Riverside/5 Points (Jacksonville's best neighborhood). You can walk to multiple bars, restaurants, yoga studios, shops, and more. We'll also send you a link to our personal G00gle doc with local tips for things to do, where to shop, and where to eat/drink. Plus, we have bikes that you can use to cruise the neighborhood! The bikes have cell phone holders & drink holders. It's perfect for couples and families as well as business and solo travelers.

Jun 12 – 19

ﺩ.ﺇ565 per night

Guest favorite

Home in Jacksonville

4.97 out of 5 average rating, 168 reviews

Coastal Lane 3/2 Clean Home in Jacksonville, Wi-fi

Reach out about our multi day discounts for weekdays! This gorgeous 3 bedroom coastal style home is your home away from home! Located in a peaceful and quiet neighborhood with perfect lake views. It's close to shopping, stores, and restaurants. - Easy highway access right off I-95 - 15 minute drive from the Jacksonville Jaguars Stadium (TIAA Bank Field) - 20 minute drive to Jacksonville Beach - 25 minute drive to Jacksonville Airport - Fast Wi-Fi -EV Charge Available for Guests in Garage

Aug 16 – 23

ﺩ.ﺇ476 per night

Guest favorite

Home in Riverside

4.99 out of 5 average rating, 164 reviews

Seconds away from the fun in Historic Riverside!

Stay on the scene in this adorable 1940s duplex suite in Historic Riverside! Ranked #6 as the most desirable neighborhood for millennials in the country! Located next door to the King Street District, enjoy walking to the restaurants, bars, cafes, and shoppes nearby. Business professionals and medical interns will be pleased with the very close proximity to the downtown offices and several hospitals. Trip for pleasure? Anything you'd want or need is either a very short walk, bike, or drive away!

Jul 18 – 25

ﺩ.ﺇ447 per night

Superhost

Home in Riverside

4.84 out of 5 average rating, 113 reviews

Riverside! Enjoy 5 points & King St. U'LL LOVE IT!

Enjoy the trendiness and fun of Riverside!! Located in the best area of the city - a quiet area but just minutes from Jacksonville's best restaurants, bars, shops, and nightlife. Unit recently renovated, 2 bedrooms, queen beds and TV in each one + sofa bed if needed. The apartment can accommodate 4 people and includes 1.5 bathrooms, fully equipped kitchen, laundry, living room, spacious dining room and a pleasantly furnished porch where you can relax having a cup of coffee. Come and enjoy it!!

Jan 23 – 30

ﺩ.ﺇ444 per night

Guest favorite

Home in Southwest Jacksonville

4.97 out of 5 average rating, 111 reviews

Unwind. Cozy Creekside Cottage near Ortega/NAS

Enjoy this charming creekfront cottage in the heart of Jacksonville. Unwind as the sun sets over the water, relax under shady cypress trees while wildlife travel about the tidal creek, enjoy cocktails on the dock, engage in boating or try your luck fishing. A boat ramp is nearby for boat launching. (Plenty of room to park Boat/Trailer on the nearly 1 acre lot ) While this unique retreat provides a tranquil getaway, it is also centrally located making it convenient for you to get around.

Oct 20 – 27

ﺩ.ﺇ393 per night

Guest favorite

Home in Jacksonville

4.98 out of 5 average rating, 111 reviews

Farmhouse by the River*Sunsets*Very Walkable*

Come enjoy this gorgeous historical home with river views. This spacious home is across the street from Jim Rink Park where you can sit and watch dolphins play. Within walking distance is the San Marco square, Baptist MD Anderson, Nemours, Wolfson’s Children’s Hospital and lots of restaurants. Near downtown and just 2.4 miles to the TIAA Bank stadium. (There are Tvs in both bedrooms & living room) If you’re looking to make Jax you’re home let me help with my knowledgeable realtor skills!

Sep 12 – 19

ﺩ.ﺇ588 per night

Guest favorite

Home in Jacksonville

4.9 out of 5 average rating, 407 reviews

Cozy Riverside Home. Walking Distance To 5-Points!

This home is located in the heart of Riverside. Cozy and aesthetic! You are centrally located in the center of 5-points. Park your car and leave it!! You are within walking distance to everything. We also have fun bikes located on the property. This home is perfect for couples, business travelers, or if you are traveling alone. - Due to Coronavirus, we’re taking extra care to disinfect frequently touched surfaces between all reservations. • Parking is available on the STREET ONLY

Jun 29 – Jul 6

ﺩ.ﺇ599 per night

Guest favorite

Home in Jacksonville

4.98 out of 5 average rating, 566 reviews

The 1910 General Store - residence

This historic country general store, listed on the National Register of Historic Places, is within easy walking distance to art galleries and cultural events, restaurants, bars, night life, and family-friendly activities. This residence is good for couples, solo adventurers, business travelers, families, and furry friends (pets, max. of 2). We are unable to allow guests to host gatherings and house parties. Off street parking available. "Historic hospitality with a southern accent!"

Jan 20 – 27

ﺩ.ﺇ666 per night

Superhost

Home in Springfield

4.83 out of 5 average rating, 103 reviews

2 BR Historic Apt near Breweries, VyStar, DT

Your family will be close to everything when you stay at this centrally-located place. Downstairs Unit located in Historic Springfield(see below) Key features: *25 min drive from closest Beach *5 min drive from Downtown Jacksonville *Near Jags stadium & concert venues * Blocks away from craft breweries and thriving restaurant scene *2 BRs, both furnished with comfortable queen size beds. *Living RM can sleep an additional person. We prefer not to rent to local residents.

Sep 1 – 8

ﺩ.ﺇ354 per night

Guest favorite

Home in Jacksonville

4.9 out of 5 average rating, 300 reviews

Retreat on the river

Deep water access to anywhere in Jacksonville with dock available. Back yard pavilion with outside kitchen, gazebo and Jamestown smoke pit 50 feet from river connecting to a remodeled home and landscaped pool. Home is not lived in and void of all personal property giving you open space to feel at home as your own. Bring your boat and tie up to the dock, or bring your kayak and take a paddle down the river. Two beds, four guest and plenty of room on couch

Oct 20 – 27

ﺩ.ﺇ510 per night

Guest favorite

Home in Jacksonville

4.95 out of 5 average rating, 111 reviews

Cozy Urban Home.

Comfortable and affordable home. It is a smoke free, pet free and cozy house. Located in a quiet neighborhood. Great place to rest . NO Pets , 0 tolerance for parties or Gatherings , smoke free home . Location : This is a good choice if you are here for a concert, game , visiting Jax or simply need palace to rest. Accessibility: House layout features steps on all points of entry , and a small bathroom. Please see "Other Details to Note "

Feb 17 – 24

ﺩ.ﺇ300 per night