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Vacation rentals in Destrehan

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Destrehan

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Guesthouse in Houma
4.87 out of 5 average rating, 172 reviews

Steph's Cozy Apartment -newly renovated

Our newly renovated apartment has all you need to enjoy a nice trip to south Louisiana. Kitchen and bath is equipped with pots, pans, spices, cutlery, utensils, dishes, and even light breakfast items. Bath has all towels and toiletries available for use. Our apartment is located upstairs above our carport but has its own private entrance along with own air conditioner/heating system. Our place will sleep 5 comfortably. We offer an Ice Machine to help with those fishing trips and local travels.

Guest favorite
A cozy living room features a dark leather sofa facing a wooden piano. Two large windows are adorned with gray curtains, allowing natural light to enter. A circular coffee table rests on a patterned rug, with decorative items like plants and a lamp adding character.
Home in Kenner
4.85 out of 5 average rating, 795 reviews

Cute ,Cozy, and Friendly In Kenner

Lovely retired couple opening their home to you. Offering all the original house which consist of 3 bedrooms, living room, kitchen, dining room, and bathroom. We live in our new addition with a private entrance and den. The house is 10 to 15 minutes from NO Airport. Quiet neighborhood. Blocks from Supermarket, Plenty of character and charm in this home. Full of personality!! Home is fully Renovated in 2016.The house has 3 outside cameras one is the doorbell and one on each side of the house.

Top guest favorite
A spacious sleeping area is highlighted by a wooden ceiling and large windows that allow natural light to fill the room. Two beds are adorned with neutral bedding. A rustic table and entertainment unit are present, contributing to the cabin aesthetic.
Cabin in Baton Rouge
4.99 out of 5 average rating, 112 reviews

River-Fun-Fishing Cabin

Beautiful high-rise cabin, with wrap around porch, overlooking the Amite River! Perfect for a romantic getaway, family fishing trip or gathering friends for some fun on the river. This place offers it all! Large yard for tent camping and outdoor games. Private beach, excellent for swimming. Boat lauch access available to guests. Huge, private, entertainment area downstairs with BBQ pit/grill and smoker, seating, and fire pit. Private fishing pond with motorless boat and fish cleaning station!

Guest favorite
A modern living area features a comfortable leather sofa facing a wall-mounted television. A stylish coffee table sits in front, complemented by decorative elements. Two potted plants add greenery, and a well-lit dining space can be seen in the background, enhancing the open layout.
Home in Kenner
4.98 out of 5 average rating, 111 reviews

Beautiful,Spacious,Quiet Residential Home

Where you'll be: Kenner, La Our home is in a very quiet neighborhood.About 8-10 min away from the New Orleans International Airport (MSY). You'll be surrounded by chain and local restaurants such as Dominoes,Papa Johns,Fiery crab,Golden coral, Laketown Bar & Grill,Willams seafood & Poboy , Smitty's seafood, Popeyes, Tacobell, Ihop, Treasure chest casino, Walmart, Rouses, Walgreens.About 5 min away from the I-10 freeway and about 15-20 drive to downtown New Orleans,Bourbon St.,French Quarter.

Guest favorite
Place to stay in St. James
4.89 out of 5 average rating, 106 reviews

Log Apartment near Airport

ACCURATELY list guests/pets when booking. If you do weed (even medical) or smoke/vape inside, we are NOT your place. Our beautiful log apt. is attached to our house but has its own separate entrance. It's close to airport, stores, LA History. Safe area,30 mins to French Quarter. We are best for non smokers, furry friends (dogs must be walked on leash) Filled with essentials. There is a covered carport over your front door (can smoke tobacco here only). We do work out of our home.

Top guest favorite
A newly renovated guesthouse exterior is shown, featuring a light-colored facade with multiple windows. Soft lighting highlights the entrance and surrounding area. A small lawn with decorative plants is visible along the pathway, while a pool is positioned nearby.
Home in Kenner
4.93 out of 5 average rating, 337 reviews

🌹Southern’s Beauty 1🌹 Very close to Airport

POOL UNAVAILABLE TEMPORARY, 1 Bedroom, 1 Bathroom, full kitchen. In a very safe and quiet neighborhood. this location has three houses the main house and two small in the back They are all for the guests. Guesthouse is a small house like the one pictured interiorly and attached. Separated from the main house and separated from the other one private entrance, and private parking area. Privet pool ,Very newly renovated, clean, all new kitchen. Private parking, 2 cable TV, snacks, coffee maker

Top guest favorite
A single-story home is presented with a brick facade and a sloping roof. The front yard features well-maintained grass and symmetrical shrubs. A wide driveway leads to the entrance, and two front doors invite guests into the space, flanked by large windows.
Home in Kenner
4.94 out of 5 average rating, 154 reviews

3Bedrm/2Bath 5 Mile/Airport 15mi/Downtown

Spacious single story In a quiet family neighborhood. Screened in porch backs up to Park and running track.Located 16 miles from downtown/French quarter. 2 Miles from the Pontchartrain center . 9 minutes from the airport. Wi-Fi included. Covered parking for two vehicles plus uncovered parking for three more. The driveway can accommodate a full size class A RV and a 50 amp plug is available.Restaurants shopping and casino all within 3 miles. Private home not shared with any other guests.

Top guest favorite
A gazebo with wooden seating is positioned alongside a dock, providing access to the bayou. The surrounding greenery adds to the natural setting, while the cottage is visible in the background, nestled among the trees. A boardwalk leads to the gazebo from the water.
Cottage in Prairieville
4.97 out of 5 average rating, 115 reviews

Beauty on the Bayou

Cozy 2 BR cottage on serene Bayou Manchac. This waterfront cabin has a large gazebo with picnic table. Boardwalk provides easy access to dock and fishing. Enjoy breathtaking views from the screened porch while you work or play. Lots of extras: WiFi, smart TV, hammock, swing, charcoal grill and fire pit. Plenty of local restaurants, grocery, etc. LSU's Tiger stadium only 34 minutes away! New Orleans 1 hour away. Raised entrance accessible only by stairs. Names of adult guests required.

Superhost
Apartment in Kenner
4.91 out of 5 average rating, 244 reviews

Private 1 bdrm apartment with kitchen in Kenner 💥

1 bed/1bath COMPLETELY PRIVATE UNIT. I am right on a Main boulevard and there’s a bus stop right across the street from the house. You can use my driveway for parking or rely on uber/ lyft if you’re flying in. I’m 1.8mi from the airport 12mi from downtown. Bus is not reliable in the city so I recommend using Lyft or a rental. Walmart is 3 blocks away from home and several restaurants are in the area. NO MORE THAN 2 GUESTS ARE ALLOWED UNLESS I AGREE TO AN EXTRA GUEST FOR A CHARGE.

Top guest favorite
Home in St. James
5 out of 5 average rating, 129 reviews

River Cottage near the Airport

Charming Cottage with all the amenities nestled in a quiet, safe neighborhood with a nearby walking trail and park. Newly-constructed 3 bedrooms with queen-sized beds, 2 bathrooms, open kitchen dining room floor plan, modern appliances, washer/dryer, spacious deck and long driveway. It is located 10 minutes away from the Airport with easy access to the French Quarters and surrounding attractions. Come enjoy the natural beauty of the Bayou and the culinary genius of the Creole cuisine.

Top guest favorite
A charming guest house is framed by lush greenery, with a light exterior and a blue roof. A wide staircase leads to the front door, bordered by decorative plants. Natural light bathes the inviting entrance, enhancing the property’s tranquil ambiance.
Guesthouse in Prairieville
4.99 out of 5 average rating, 288 reviews

The Blue Heron Guest House-6 acres on the bayou.

Take it easy at this unique getaway. Located on Bayou Manchac on a gated 6 acre estate. The Blue Heron Guest House is a great place to just get away, enjoy nature, canoe (provided), fish the pond or the bayou, birdwatching (lots of birds), etc. The property does have a boat slip and a small boat launch for those who want to explore the area by boat. Bayou Manchac connects to the Amite River nearby. We can’t wait to share our paradise with you!

Top guest favorite
A single-story brick home is shown, featuring a black shingle roof and large front windows framed by dark shutters. The front door is centrally located, and a spacious lawn extends in front of the house, bordered by utility poles and an open field.
Home in Vacherie
4.97 out of 5 average rating, 112 reviews

River Retreat

River Retreat is situated directly on The Great River Road in Vacherie. This private home is less than an hour drive from New Orleans and Baton Rouge, making it the perfect location! We strive to give you an inviting comfortable place to call your home away from home. We are located minutes from Oak Alley and other plantation homes, swamp tours, and The Great Mississippi River. Our location makes RR perfect for your next getaway!

Popular amenities for Destrehan vacation rentals