House vacation rentals in DeSoto County

Find and book unique houses on Airbnb

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Popular amenities for DeSoto County house rentals

House rentals with a pool

Guest favorite
Home in Punta Gorda
4.95 out of 5 average rating, 171 reviews

Seasonal vacation rental with Heated pool

MichelleRating, 5 stars2 weeks ago
Our stay was perfect. The house was exactly as described and had everything we needed - including beach towels/ beach chairs / umbrella and coolers. Robert was fantastic to work with and responded very quickly with a few questions I had about the house. We will definitely will stay here again!
Top guest favorite
Home in North Port
5 out of 5 average rating, 38 reviews

SunshineVilla/Pool/spa/beach /luxury/new

MichelleRating, 5 stars1 week ago
Inessa’s home in North Port was absolutely stunning! The house was pristine, with a quaint and beautiful layout, spotlessly clean. The pool was a magnificent highlight, and the home was well-equipped with plenty of towels, washcloths, coffee, tea, silverware, dishware, and cooking utensils. They even left water in the fridge for us! The king-size bed and pillows were incredibly comfortable, making our stay even better. Shops were close by, and Inessa was super responsive and easy to reach. We highly recommend this gem if you’re looking for something very nice and cozy! We can’t wait to come back! – Thank you Inessa ❤️ Larry & Michelle
Top guest favorite
Home in Port Charlotte
4.97 out of 5 average rating, 101 reviews

PORT CHARLOTTE FLORIDA RETREAT, 2/2, PRIVATE POOL

RogerRating, 5 stars1 month ago
This was our second year staying at Dale and Louise's property. Always exceeds our expectations. Clean, tidy, -- perfect for 4 people! or more! The pool is amazing! We'll be back next year!
Guest favorite
Home in Port Charlotte
4.92 out of 5 average rating, 48 reviews

Serenity Lakeside Villa - KING BED - Heated Pool

Dayflower PropertiesRating, 5 stars3 weeks ago
Host was great to work with, very responsive!. House was clean, near grocery, restaurants and some shopping. Loved the backyard pool, very relaxing and quiet!
Guest favorite
Home in Punta Gorda
5 out of 5 average rating, 6 reviews

Tripoli House

CarolRating, 5 stars3 months ago
We are very sad to leave this beautiful town. It will be hard to go back to ice and snow. We had wonderful weather, the house was great and Greg responded immediately to questions we had and did everything he could to make everything good. We hope to be back.
Guest favorite
Home in Port Charlotte
4.85 out of 5 average rating, 226 reviews

Peaceful Port Charlotte 2Bd/2Ba on water

RobertRating, 5 stars3 weeks ago
We were very relaxed at this home because it felt like home. Home was completely and fully stocked with everything you needed. We even used items in the garage during our stay ( lawn chairs, floating devices and there were even fishing poles if we wanted to use). The HVAC and hot water tank looked new and the washer and dryer was great. In the event we ever travel in that area again I will definitely be staying at this home if it is available. For myself and my family Thanks Troy for making our stay easy and great!
Top guest favorite
Home in Port Charlotte
5 out of 5 average rating, 25 reviews

Florida Getaway

JoAnnaRating, 5 stars1 month ago
Lisa was a wonderful host; she is very responsive and easy to communicate with. The home is beautiful! We loved every moment of our stay. The pool was immaculate, and the outside area was private and tranquil, perfect for enjoying your coffee in the morning. The inside of the home was spotless and spacious. The furniture was comfortable, and the kitchen was the most fully stocked one we had ever seen on Airbnb. We'll come back again. I was sad to leave!
Guest favorite
Home in North Port
4.96 out of 5 average rating, 101 reviews

Flourish in Florida heated pool & spa

JulieRating, 5 stars1 month ago
This home was perfect! It was spotless, smelled warm and inviting, and had every amenity you could want. The pool was the icing on the cake!! I would highly recommend this location as we all truly enjoyed our stay and would love to return again!!

Weekly house rentals

Top guest favorite
Home in Arcadia
4.96 out of 5 average rating, 92 reviews

Country Villa w/patio and huge yard for parking

ArdithRating, 5 stars1 week ago
Kendall and Rhonda are terrific hosts. They both came quickly when we had a problem. The house was super clean and filled our need.
Superhost
Home in Arcadia
4.81 out of 5 average rating, 37 reviews

Sunshine Acres

TammyRating, 5 stars3 weeks ago
We stayed from Wed to Sun, the location was close to family I won’t lie the neighborhood had me worried but once we walked inside we were genuinely impressed and the inside was extremely clean and very accommodating for us and our 1yr old grandchild, we felt at home. We would highly recommend staying here and will most certainly book again when we come to visit family again.
Guest favorite
Home in Arcadia
5 out of 5 average rating, 5 reviews

Farm Cottage in Arcadia

AaronRating, 5 stars3 months ago
Nice, clean place that was easy to get to. Exactly what we needed for a long weekend since central Florida. Ana is a great host!
Home in Arcadia
4.86 out of 5 average rating, 7 reviews

Recent Built Guest House

MelissaRating, 5 stars4 days ago
We absolutely loved our stay. The surroundings were beautiful and so quiet away from the crazy traffic we are use to. Gerald was always quick to answer any questions, he was so thorough in explanations. The home was very very nice, clean, cozy, quiet. We will definitely come here again. We have already shared this place with friends and family for future stays. We cant thank Gerald enough for the great stay.
Guest favorite
Home in Arcadia
5 out of 5 average rating, 19 reviews

Sly Gator House

MattRating, 5 stars1 month ago
Very nice place right on the river will be staying again!
Guest favorite
Home in Arcadia
4.97 out of 5 average rating, 112 reviews

Hernando House 3/2 w private backyard and patio

ChristinaRating, 5 stars5 days ago
This was the 2nd time we booked this home and it was just as perfect the 2nd time as it was the first. Hosts are great with communication and the home is clean and close to everything in Arcadia.
Superhost
Home in Arcadia
4.81 out of 5 average rating, 36 reviews

Brand new home 3/2 large patio, Citrus home

JoseRating, 5 stars1 day ago
Excelente place I will come back soon!!!! Thanks so much
Guest favorite
Home in Arcadia
4.89 out of 5 average rating, 18 reviews

Historic Wheeler House

AmieRating, 5 stars3 months ago
This house is the perfect cozy space. Very comfortable & close to restaurants. We stayed here during our visit to peace River and it was perfect, the outdoor space was cute & cozy. The pictures simply do not do this place justice for how cute it is decorated with all the vintage furniture and decor. We would definitely stay here again.

Private house rentals

Top guest favorite
Home in Arcadia
4.96 out of 5 average rating, 92 reviews

Country Villa w/patio and huge yard for parking

ArdithRating, 5 stars1 week ago
Kendall and Rhonda are terrific hosts. They both came quickly when we had a problem. The house was super clean and filled our need.
Superhost
Home in Arcadia
4.81 out of 5 average rating, 37 reviews

Sunshine Acres

TammyRating, 5 stars3 weeks ago
We stayed from Wed to Sun, the location was close to family I won’t lie the neighborhood had me worried but once we walked inside we were genuinely impressed and the inside was extremely clean and very accommodating for us and our 1yr old grandchild, we felt at home. We would highly recommend staying here and will most certainly book again when we come to visit family again.
Guest favorite
Home in Arcadia
5 out of 5 average rating, 5 reviews

Farm Cottage in Arcadia

AaronRating, 5 stars3 months ago
Nice, clean place that was easy to get to. Exactly what we needed for a long weekend since central Florida. Ana is a great host!
Home in Arcadia
4.86 out of 5 average rating, 7 reviews

Recent Built Guest House

MelissaRating, 5 stars4 days ago
We absolutely loved our stay. The surroundings were beautiful and so quiet away from the crazy traffic we are use to. Gerald was always quick to answer any questions, he was so thorough in explanations. The home was very very nice, clean, cozy, quiet. We will definitely come here again. We have already shared this place with friends and family for future stays. We cant thank Gerald enough for the great stay.
Guest favorite
Home in Arcadia
5 out of 5 average rating, 19 reviews

Sly Gator House

MattRating, 5 stars1 month ago
Very nice place right on the river will be staying again!
Guest favorite
Home in Arcadia
4.97 out of 5 average rating, 112 reviews

Hernando House 3/2 w private backyard and patio

ChristinaRating, 5 stars5 days ago
This was the 2nd time we booked this home and it was just as perfect the 2nd time as it was the first. Hosts are great with communication and the home is clean and close to everything in Arcadia.
Superhost
Home in Arcadia
4.81 out of 5 average rating, 36 reviews

Brand new home 3/2 large patio, Citrus home

JoseRating, 5 stars1 day ago
Excelente place I will come back soon!!!! Thanks so much
Guest favorite
Home in Arcadia
4.89 out of 5 average rating, 18 reviews

Historic Wheeler House

AmieRating, 5 stars3 months ago
This house is the perfect cozy space. Very comfortable & close to restaurants. We stayed here during our visit to peace River and it was perfect, the outdoor space was cute & cozy. The pictures simply do not do this place justice for how cute it is decorated with all the vintage furniture and decor. We would definitely stay here again.

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