House vacation rentals in DeSoto County
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Top-rated house rentals in DeSoto County
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for DeSoto County house rentals
House rentals with a pool
Home in Punta Gorda
4.96 out of 5 average rating, 131 reviewsPunta Gorda Isles Gem with Saltwater Spool
Oct 11 – 18
Home in Port Charlotte
4.85 out of 5 average rating, 213 reviewsPeaceful Port Charlotte 2Bd/2Ba on water
Dec 16 – 23
Home in Port Charlotte
4.84 out of 5 average rating, 155 reviewsWaterfront Pool and Dock! Great Family Retreat
Nov 30 – Dec 7
Home in Englewood
4.93 out of 5 average rating, 125 reviewsStunning Home, Saltwater Heated Pool By the Beach
Oct 5 – 12
Home in Sebring
4.79 out of 5 average rating, 101 reviewsFlorida Oasis Solar Panel Pool w/Fire Pit & Grill!
Oct 22 – 29
Home in Port Charlotte
4.94 out of 5 average rating, 109 reviewsLuxury Bungalo with Pool in Port Charlotte
Nov 18 – 25
Home in Port Charlotte
4.81 out of 5 average rating, 31 reviewsOasis with pool in the middle of West Coast, FL
Oct 6 – 13
Home in Port Charlotte
4.91 out of 5 average rating, 11 reviewsThe Westbrook House
Aug 27 – Sep 3
Weekly house rentals
Home in Arcadia
5.0 out of 5 average rating, 26 reviews"Old Florida" Getaway
Dec 3 – 10
Home in Punta Gorda
4.86 out of 5 average rating, 14 reviewsUnique 3 Beds Waterfront/dock/fish/family friendly
Jun 7 – 14
Home in Arcadia
5.0 out of 5 average rating, 53 reviewsSly Gator House
Oct 3 – 10
Home in Venus
4.94 out of 5 average rating, 35 reviewsThe Deer Retreat at Venus
Aug 13 – 20
Home in North Port
5.0 out of 5 average rating, 18 reviewsEntire light filled Florida 2 bedroom/2 bath home
May 6 – 13
Home in Punta Gorda
4.93 out of 5 average rating, 71 reviewsCozy Cottage in Historic Downtown Punta Gorda
May 16 – 23
Home in Punta Gorda
4.9 out of 5 average rating, 29 reviewsHouse in Punta Gorda: Hot tub, Patio, Pet Friendly
Aug 15 – 22
Home in North Port
5.0 out of 5 average rating, 27 reviewsSimply Beautiful, Comfortable Home Awaiting You!
May 8 – 15
Private house rentals
Home in Port Charlotte
5.0 out of 5 average rating, 9 reviewsSunshine Retreat | NEW 4/2, King Bed, Near Beaches
May 13 – 20
Home in Lake Placid
4.97 out of 5 average rating, 91 reviewsHome in quiet area with lake access
Jul 14 – 21
Home in Port Charlotte
4.95 out of 5 average rating, 19 reviews♥Pet Friendly ✔ Close to shops ☀10 mins to beach☀
Jul 12 – 19
Home in Port Charlotte
5.0 out of 5 average rating, 31 reviews3BR Home Private Heated Pool in Port Charlotte
Aug 5 – 12
Home in North Port
5.0 out of 5 average rating, 13 reviewsIggy's Place
Jan 15 – 22
Home in North Port
4.92 out of 5 average rating, 13 reviewsCute Saltwater Pool Home close to Gulf Beaches!
Aug 8 – 15
Home in Punta Gorda
4.92 out of 5 average rating, 78 reviewsComfy 2 Bedroom Coastal Home
May 12 – 19
Home in Wauchula
4.84 out of 5 average rating, 49 reviewsCasa Linda Entire 3-bedroom home with free parking
Nov 1 – 8
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