
Family-friendly vacation rentals in DeSoto County
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in DeSoto County
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for DeSoto County family-friendly rentals
Family-friendly home rentals with a hot tub

Lake Beach 7 Bedroom, 4 full Bath + 3rd floor play

Sunny South-Facing Heated Pool & Spa on Lake

Luxurious Mangoe 4 bed 2 bath, salt water pool spa

Paradise in PG Isles w/gorgeous pool/spa

Home away from home pool/spa

Tropical Glamping with Hot Tub

Oz Cottage hot tub, Pool, 2.9 m beach

Lake Denton Diver's Paradise Swim-Dive-Boating
Family- and pet-friendly home rentals

Historic Wheeler house Extra

Arcadia 4BR Getaway– Clean & Peaceful Stay

Camp Independence Alligator Hunt

Santa's Cottage

Historic Home in Arcadia

Silverbullet Stables Tent site

Silve Bullet Stables Tent Site 2

Love Cabin
Family-friendly home rentals with a pool

Seasonal vacation rental with Heated pool

Waterfront Paradise with Heated Pool & Dock

NEW Family Fun 4BR Home & Pool on 10 acres

Boaters Dream, full refund*, heated pool, sleeps 6

Glamping+Free Horseback Riding+Petting Farm

Your Slice of Heaven quiet Estate -great location

Fun Luxury Stay: Mini Golf, Heated Pool, Bowling

Sea Blue - 3/2 Home with Screened-in Heated Pool
Destinations to explore
- Siesta Beach
- Crescent Beach
- Turtle Beach
- Caspersen Beach
- Lido Key Beach
- Streamsong Resort
- Manasota Key Beach
- River Strand Golf and Country Club
- Point Of Rocks
- Marie Selby Botanical Gardens
- Englewood Beach
- North Jetty Beach
- Stump Pass Beach State Park
- Lakewood National Golf Club
- South Jetty Beach
- Gasparilla Island State Park
- Blind Pass Beach
- Boca Grande Pass
- Myakka River State Park
- Tara Golf & Country Club
- Waterlefe Golf & River Club
- Del Tura Golf & Country Club
- Manatee Park
- Van Wezel Performing Arts Hall