Places to stay near Cleveland Botanical Garden

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Top-rated vacation rentals near Cleveland Botanical Garden

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Top guest favorite
A spacious outdoor area features a jacuzzi next to a dining table with chairs and an umbrella. Stone flooring surrounds the space, while a brick wall provides a rustic backdrop. Decorative lighting adds a calming touch to the environment.
Vacation home in Cleveland
5 out of 5 average rating, 280 reviews

New Cleveland Apt: Little Italy! Massage&Hot tub!

Fall in love with this charming, newly updated 1-bedroom, 1-bath lower unit triplex apartment situated just minutes from downtown and University Circle. Complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation rental delivers all the essentials so you can spend more time relaxing and exploring. Nearby Case Western University, UH Hospital, University Circle, Cleveland Museum of Art, Cleveland Clinic, Severance Hall, Botanical Garden, and much more!!

Top guest favorite
A bright living room features a cozy orange sofa paired with two armchairs adorned with patterned cushions. A wooden coffee table sits in the center, complemented by a decorative rug. Natural light filters through the windows, enhancing a welcoming atmosphere.
Apartment in Cleveland Heights
5 out of 5 average rating, 197 reviews

The Farmhouse - 1 Bdrm Apt in a Great Location

Welcome to this 2nd flr 1 bd/1 ba private apartment in a charming 1880s farmhouse located in a friendly walkable neighborhood. Full kitchen with all you need to make your own meals, washer/dryer and separate office inside the unit. Free off-street parking. You are only: 5 min walk to Starbucks, a variety of restaurants, bars, shops, trails 5-10 min drive to Cleveland Clinic, University Hospitals, Case Western, museums, parks, Little Italy and more 15 min drive to major attractions and Lake Erie

Top guest favorite
A modern kitchen area features gray cabinetry and a stainless steel sink, complemented by a sleek, dark countertop. A black stove and microwave are seen, alongside a refrigerator with a textured finish. White tiles line the backsplash, reflecting light from the overhead fixture.
Home in Cleveland
4.93 out of 5 average rating, 331 reviews

Historic Little Italy Garden Apartment

Stylish garden apartment. This retreat blends modern comfort with the vibrant cultural charm of Historic Little Italy. Steps away from shops, restaurants, and lively bars. Wade Oval Park is a nearby cultual hub, home to The Art & Natural History Museums and Botanical Gardens. Easy access to Case Western Reserve, Cleveland Clinic and University Hospital. Walk to the beautiful Lakeview Cemetary or take transit downtown to 4th street. Perfect for short or long stays. Book for a memorable time.

Guest favorite
A living area featuring a dark sofa and a cozy brown armchair, arranged around a light coffee table on a patterned rug. A wall-mounted smart TV is positioned across from the seating. Natural light enters through three windows, illuminating the space.
Home in Cleveland
4.79 out of 5 average rating, 374 reviews

The Cleveland Coop

We are Logan & Andrea. The Coop is on the 1st floor of a duplex. Everything in the apt is new. We have a medical lift chair for guests recovering from surgeries. There is free laundry, wifi, and a smart TV. We are 1 mile from the Cleveland Clinic and CWRU. We are near parks, museums and walking areas. We are a $10-15 Uber ride from Dwntwn Clev. Please note, this is a multi ethnic community, If you are uncomfortable around people who look different from you, our place is not for you

Top guest favorite
A spacious living area is presented, featuring a comfortable sofa and a soft area rug. A modern coffee table sits in the center, while a large TV is positioned against the wall. Natural light filters in through sloped ceilings and a nearby window.
Apartment in Cleveland Heights
5 out of 5 average rating, 113 reviews

New! “Modernistic Retreat”

Elevate your stay in this bright, elegant and spacious 3rd floor apartment that offers the perfect blend of tranquility and urban convenience. Less than 10 minutes from Cleveland Clinic, 8 min from Case Western University, 17 min from Rock and Roll Hall of Fame, 18 min from Cleveland Browns Stadium, 20 min from Downtown, 28 min from Cleveland Airport and 45 min from Blossom Music Venue. Moments from charmed local neighborhoods such as Coventry, Little Italy, Cedar Fairmont and Lee Rd.

Top guest favorite
A cozy living space features a genuine leather couch paired with an accent chair and a glass coffee table. A large wall-mounted TV is visible, and a houseplant adds a touch of greenery. Sliding barn doors lead to a bedroom area and dining space beyond.
Home in Cleveland
4.95 out of 5 average rating, 38 reviews

Mid-Century Modern Retreat in Little Italy

Nestled in the vibrant yet peaceful and safe Little Italy neighborhood of Cleveland, this newly remodeled Mid-Century Modern style 2bed/1bath Lower unit is within walking distance to the best Cleveland has to offer. Enjoy a stroll to Case Western Reserve University, University Circle, the Cleveland Museum of Art, Cleveland Botanical Garden, and more. Discover local shops, bakeries, and renowned restaurants that give Little Italy its charm. The RTA redline station is a five minute walk.

Superhost
A spacious living area features a dining table with wooden chairs, accompanied by a red couch and a matching armchair. Natural light enters through multiple windows, illuminating the room. A stylish coffee table sits in the center, complemented by a decorative area rug.
Apartment in Cleveland
4.72 out of 5 average rating, 50 reviews

Cle Suites 2BR/1BA | 5 min Walk to Cle Clinic #9

Fully furnished luxury apartment that has been completely renovated combining old-time 19th century charm with modern amenities. Just move in with your suitcase! Within walking distance to the Cleveland Clinic Campus (5 min walk from main hospital). It’s also near University Hospitals, CWRU, Great University Circle, Downtown Cleveland, and Little Italy. This location is perfect for those receiving medical treatments and their families, doctors on rotation, travel nurses, and interns.

Top guest favorite
A welcoming entrance leads to a sunny sitting room featuring a blue sofa beside a wooden rocking chair. A small side table with a lamp is visible near a large window framed by soft curtains, allowing natural light to enter the space.
Guest suite in Cleveland Heights
4.96 out of 5 average rating, 517 reviews

Private Victorian suite with two rooms and a bath

You’ll love this newly remodeled third floor suite in our large century home located near Coventry Village/University Circle/Cleveland Clinic. The private suite with separate entrance and stairs has an air conditioned large bedroom with a firm queen bed, a sunny sitting room with a futon and a bathroom (shower) finished in Victorian ornate wood trim! Off street parking is in the rear. Our place is great for couples or business travelers, and the futon can sleep a child on.

Superhost
Guest suite in Cleveland
4.9 out of 5 average rating, 131 reviews

3 min Drive to Cle Clinic Free Parking

Updated Cozy home, conveniently located three minutes from Cleveland Clinic and University Hospital by car. 16 minute walk to the clinic. Perfect for medical treatment patients/families, healthcare professionals, student Our Century Home has charm combined with modern amenities 5-10 mins from CWRU, Downtown Cleve , Little Italy and Major Sports Venues Home features 55”smart TV (Netflix, Hulu, Disney Plus included), wi-fi, private on site parking, keyless entry, Queen bed

Guest favorite
A light-filled bedroom features a comfortable bed with a checked comforter and a yellow accent pillow. The space includes a chair and desk, with a cozy sitting area visible through an open door. Bright curtains frame the windows, illuminating the warm wood floor.
Apartment in Cleveland
4.83 out of 5 average rating, 114 reviews

Pet Friendly 2BR in Little Italy

Enjoy a stylish experience at this centrally-located place in the heart of Little Italy. Newly renovated with a minimalist design. You are just down the street from restaurants, bakeries and bars. The RTA redline is also a two minute walk away, which takes you straight downtown as well as to the airport. Also within walking distance of Cleveland Clinic and University Circle. The apartment is located on the first floor. There is no private parking at the property.

Superhost
The studio features a spacious bed framed by soft, light-colored drapes and a large mirror above a wooden headboard. A cozy seating area is provided with a black armchair and round table, while an overhead fan adds comfort.
Apartment in Cleveland
4.73 out of 5 average rating, 91 reviews

Peaceful Mansion Studio | Steps from Cle Clinic

🛏 Queen bed • 1 bathroom • Sleeps 2 🏛 Historic Cleveland mansion • Second floor studio 🍳 Full kitchen • Smart TV • Streaming apps 🚗 Free off-street parking • Quiet location 💤 Peaceful, comfortable & full of charm 📍 Directly across from Cleveland Clinic Main Campus (10 min walk, 2 min drive) Step back in time while enjoying modern comfort in this bright and colorful studio nestled inside a beautifully restored Cleveland mansion.

Top guest favorite
A cozy living space features subdued green walls and warm wood floors. A plush sofa and textured throw invite relaxation. A dining area with seating for four is visible, while the adjacent kitchen is softly lit, enhancing the homey atmosphere.
Apartment in Cleveland
4.94 out of 5 average rating, 137 reviews

Invidiosamente Verde #3 *Family Run*

Located in Cleveland’s historic Little Italy, my two-bedroom, one-bath units are steps from Mayfield Road’s restaurants, bakeries, and galleries, with easy access to University Circle, Case Western, and the Cleveland Clinic. Hosting since 2011, I personally manage everything to provide a level of care big companies can’t match. I’m always improving my spaces to ensure a comfortable stay—if something’s missing, just let me know!

Popular amenities for vacation rentals near Cleveland Botanical Garden