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Vacation rentals in Chepo

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Chepo

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Home in Distrito de Monterico
5.0 out of 5 average rating, 12 reviews

Cozy and Safe Atmosphere Near the Airport

An ideal house to enjoy a comfortable and peaceful stay with independent access. It has 2 spacious bedrooms (1 with a queen-size bed and air conditioning, the other with 2 single beds and a fan), 1 full bathroom, a living room with comfortable furniture, a dining room, an equipped kitchen, a laundry room, free parking, a terrace, Wi-Fi, and a 50" TV. Located on a traffic-free street with easy access to main avenues, shopping malls, and transportation, and just minutes from the international airport.

Guest favorite
Apartment in Panama City
4.92 out of 5 average rating, 165 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Top guest favorite
Place to stay in Panama City
5.0 out of 5 average rating, 21 reviews

Casa Condal - Your Luxury Retreat in Cerro Azul

Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.

Top guest favorite
Boat in San Blas Islands
5.0 out of 5 average rating, 8 reviews

Private Catamaran live on board

Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Guest favorite
A stone pathway leads through lush tropical foliage toward a welcoming entrance. Tall trees and vibrant greenery frame the path, creating a serene approach to the property, which is partially visible in the background, surrounded by nature's tranquility.
Home in Panama City
4.97 out of 5 average rating, 87 reviews

Mountain Retreat

Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Top guest favorite
A rustic house is nestled among lush greenery, with sturdy stone columns supporting a covered entrance. The surrounding trees provide shade and a sense of privacy, enhancing the tranquil setting. The pathway leading to the door is lined with grass and natural foliage.
Cottage in Panama City
4.9 out of 5 average rating, 59 reviews

Moon House River Dreams Cerro Azul

Fresh and cozy rustic-style country house, located in the high mountains of Cerro Azul. Quiet and private, surrounded by nature and exotic fauna. A river runs through the property with small waterfalls. Ideal for families and couples, groups, retreats, celebrations, up to 5 people. You can breathe peace, tranquility and freshness. Ideal for rest, vacation, remote work or celebration. The stay can be for two nights, weeks, months or a year with a good discount. Pets are welcome for extra fee.

Guest favorite
A private hot tub sits at the edge of a tranquil lake, surrounded by lush greenery. The serene water reflects the clear blue sky, while the distant hills provide a peaceful backdrop. The tub's blue tiles contrast with the natural landscape.
Cabin in Panama City
4.92 out of 5 average rating, 72 reviews

#1 Cabin on the Lake Cerro Azul

Escape to the tranquil beauty of Cerro Azul, Panama and stay in our cozy lakeside cabin. With breathtaking views of the surrounding mountains and direct access to the lake, this is the perfect retreat for nature lovers. Enjoy fishing, kayaking, or simply relax on the private dock and soak in the serenity of the surroundings. Our fully equipped cabin has everything you need for a comfortable stay, including a full kitchen, comfortable bedroom, and a spacious balcony with panoramic views.

Guest favorite
A cozy living area is observed with a round dining table surrounded by four upholstered chairs. A sofa and armchair face a TV unit, while large windows provide natural light and views of the surrounding greenery.
Apartment in Panama City
4.96 out of 5 average rating, 46 reviews

Canal Studio

Ground floor apartment, ideal for groups who love good taste, jungle landscapes and confort. Near the apartment there are paths to the Panama Canal, hills and jungle. Enjoy the elegance, nature and history of the Panama Canal with your family and friends in a jungle environment, quiet and very confortable. Ground floor apartment, ideal for groups who love good taste, jungle landscapes and comfort. Near the apartment there are paths to the Panama Canal, hills and jungle.

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 221 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Top guest favorite
Apartment in San Felipe
4.97 out of 5 average rating, 36 reviews

Walk to Everything | Luxury Stay in Casco Viej

Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Guest favorite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Apartment in San Francisco
5.0 out of 5 average rating, 82 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more

Guest favorite
Cabin in Panama City
4.93 out of 5 average rating, 92 reviews

The Crystal House: Luxury Modern Wood Cabin

Create unforgettable memories at this unique and family-friendly place. Stay in a cabin in the middle of Chagres National Park, 50 minutes from the city. You can be in contact with nature while having all the comforts of a luxury accommodation. With one of the best views of the city, you can enjoy a good barbecue, a nap in the hammock, or a meeting around the fireplace. Relax and connect with the beautiful green of Panama. We'll be waiting for you!

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