Family-friendly vacation rentals in Cayce

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Cayce

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite
A dining area is presented with a round table surrounded by four wooden chairs. A delicate chandelier provides overhead lighting, while a window with sheer curtains allows natural light to enter. A soft-colored wall enhances the serene space, complemented by a wall art piece.
Home in West Columbia
4.93 out of 5 average rating, 287 reviews

Lucy’s Place

This 950 sq ft minimalist home is the perfect place to relax with family and friends. This West Columbia home is in a convenient spot for you to spread out and make yourself at home. The home is only 2 miles off of the interstate if you are just traveling through. You’ll be about 10 minutes from the University of South Carolina, Colonial Life Arena, the Statehouse, Riverbanks Zoo, Williams Brice Stadium, the Vista, The Columbia Riverwalk and many more local attractions if you are staying a while

Guest favorite
A comfortable living space features a black leather sofa draped with a soft throw blanket. A round black coffee table with gold accents is positioned in front of the seating. A tan armchair completes the arrangement, set against soft beige carpet and light gray walls.
Home in Cayce
4.9 out of 5 average rating, 212 reviews

Columbia’s Best Airbnb

Take it easy at this unique and tranquil getaway. Our Airbnbs are the nicest in each town. From our known luxurious mattresses to the best kept secret… 3D luxury digital Massage chairs relax you from any stressful situation. See why we are ambassador Airbnb host. Stay at this location and you are 5 to 10 minutes to the USC baseball, basketball and Football. Campus is same. Airport is 4 miles. Great kid activity at EdAdventure kid museum. I 26, I-77 and downtown Columbia are minutes away.

Top guest favorite
A charming outdoor space is surrounded by lush greenery, featuring a table with chairs and a wooden bench. The cottage is visible with vibrant yellow doors, while the nearby building provides additional context. Colorful flowers are arranged in pots throughout the garden.
Guesthouse in Elmwood Park
4.89 out of 5 average rating, 981 reviews

Lizzi & Scott’sTiny Guest House secluded USC-Vista

Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in. STRO-000579-03-2024

Top guest favorite
A modern kitchen with sleek white cabinetry and granite countertops is highlighted. Four black bar stools are positioned at an island, and stainless steel appliances, including a stove and refrigerator, are visible. Natural light enters through multiple windows, creating a bright and functional space.
Home in West Columbia
5 out of 5 average rating, 106 reviews

Golden Reflections Getaway

Welcome to the Golden Reflection Getaway—a spacious, stylish retreat perfect for families and groups. Enjoy this 2,600+ sq. ft. spacious family area with three luxury themed bedrooms upstairs and extra sleeping options with a full bathroom on the main level. Tucked away in a peaceful neighborhood, just 7 minutes from the vibrant heart of Downtown Columbia and 18 minutes from Fort Jackson. Relax, recharge, and make lasting memories in this thoughtfully designed and comfortable home.

Guest favorite
The exterior of a detached studio apartment is shown, featuring a light-colored façade and a charming blue door. Two large windows provide natural light, while a shaded carport is visible on the left. Lush greenery surrounds the entrance, contributing to a serene environment.
Guesthouse in Cayce
4.89 out of 5 average rating, 157 reviews

The Avenues Bungalow

This space is great for a solo traveler or a couple! Great location, quiet neighborhood, close to everything. Mile and a half from USC campus (Carolina Baseball stadium, Colonial Life Arena and State house). Five miles from airport. Three miles from Williams-Brice Stadium. Three Miles from 5 points. Music venues, restaurants and riverwalk around the corner! Please note: This is a studio apartment in the back of a single family home. Private driveway, entrance and space.

Guest favorite
A charming tiny home is surrounded by trees and features a welcoming front porch with wooden decking. An outdoor fire pit, with several Adirondack chairs arranged around it, creates a cozy gathering space. Warm light emanates from the windows, highlighting its cozy atmosphere.
Tiny home in West Columbia
4.96 out of 5 average rating, 110 reviews

Lux Tinyhome near DT/USC/Ft. J.

Experience unique glamping in a "tiny but mighty," private 300-sq-ft one-of-a-kind retreat. Built around trees and fully fenced for seclusion, it includes washer/dryer, a kitchenette, and large windows with blackout drapes for cozy nights. Perfect for couples or small families, located beside our historic farmhouse airbnb. Prefer an ever more elevated luxury escape? Are your desired dates booked? Discover our new close by Luxury Skylight Spa Cottage (in our profile).

Top guest favorite
A cozy dining area features a round wooden table surrounded by a mix of modern and rustic seating. Natural light is welcomed through nearby windows, and warm lighting is provided by hanging pendant fixtures. A decorative storage unit displays various items, adding character to the space.
Home in Cayce
4.96 out of 5 average rating, 162 reviews

High-styled Historic - (UofSC)

Built in 1959, this home has been completely remodeled with modern luxuries, and original hardwood floors throughout still tell the tales of decades of love and history. The decor gives a nod to a New York City loft style space, with a blend of both clean modern lines and warm rustic finishes. 1.2 mi - Steel Hands Brewing 1.8 mi - University of South Carolina 2.2 mi - Riverbanks Zoo & Garden 3.6 mi - Williams Brice Stadium 4.9 mi - Columbia Metropolitan Airport

Top guest favorite
A cozy living area is presented with a black sofa adorned with a red throw. Two chairs in green and pink are positioned opposite a wooden table, enhancing the eclectic charm. Large windows allow ample natural light, complementing the industrial design.
Loft in Columbia
4.9 out of 5 average rating, 315 reviews

Downtown Industrial Loft

A great one bedroom space in historic downtown Columbia, SC in the Land Bank Lofts building. It is within walking distance to all you may need in the area including fine and casual dining, coffee shops, museums and plenty of entertainment. The loft was remodeled with an industrial feel with high ceilings and exposed venting and ductwork but equipped with all conveniences. It has been decorated with an eclectic flair with local historic pieces and artifacts.

Guest favorite
A bright living area features a soft color palette with a cozy rug underfoot. A pair of comfortable sofas are positioned around a wooden coffee table. Light from windows illuminates the space, enhancing the welcoming atmosphere, and an open archway leads to the dining area.
Home in Cayce
4.96 out of 5 average rating, 107 reviews

In Columbia Metro! Easy drive to Fort Jackson/USC

Metro Columbia. 1.5 miles to USC. 9 miles to Fort Jackson! Entire single family home. Two bedrooms. One has a KING bed and the other has a QUEEN bed. One bath. Additional rollaway bed in an enclosed sunroom. Includes linens, sofa, loveseat, refrigerator, dishwasher, garbage disposal, wash machine, dryer, outdoor covered patio with rocking chairs and dining table overlooking the huge fenced, private backyard. Bright, comfortable, quiet. Plenty of parking.

Guest favorite
A charming brick exterior features a welcoming entrance with steps leading to a covered porch adorned with plants. Large windows allow natural light to brighten the interior. Surrounding greenery provides a tranquil setting in a peaceful residential neighborhood.
Apartment in Earlewood
4.93 out of 5 average rating, 318 reviews

The Toad Abode Studio

Relax and unwind in this cozy, centrally located studio. Perfect for travelers, the space features a comfortable double bed, work desk, cozy reading chair, and TV for your downtime. The kitchenette area includes a microwave & mini fridge with ample coffee & tea supplies, while the bright bathroom offers plenty of natural light. All the essentials you need for a comfortable stay. **Checkout on a Monday for more options at a discounted Sunday rate.

Guest favorite
A spacious bedroom is furnished with a metal bed frame and white bedding. Two nightstands flank the bed, each with a lamp. Natural light enters through two windows adorned with white curtains, complemented by a textured gray throw and decorative accessories on the bed.
Home in Earlewood
4.86 out of 5 average rating, 199 reviews

Cozy Boho Downtown Duplex

This chic bohemian inspired duplex is as close as you can get to Downtown Columbia, while still being tucked away in a cozy and quiet neighborhood. Nestled in Earlewood, steps from historic Elmwood Park, you’ll be less than 10 minutes from all the attractions. Minutes from USC, Prisma, Colonial Life Arena, Riverbanks Zoo, and Lexington Medical Center, you will be perched in the heart of Downtown Columbia. Fort Jackson is 15-20 minutes away.

Guest favorite
A small guesthouse is depicted with a light-colored exterior and a single door. Lush greenery surrounds the entrance, including various potted plants. A simple pathway leads to the door, creating a welcoming approach.
Guesthouse in Shandon
4.78 out of 5 average rating, 404 reviews

Writer's haven in private guesthouse.

Cozy guesthouse makes an ideal writer's retreat! Located in an attractive, quiet neighborhood close to dining and shopping. On-street parking on non-busy side street. Hosts will work with you on creating fun rewards for writing goals. Space has a microwave, refrigerator, coffee maker, and electric kettle, and hosts will provide coffee, tea, wine, bottled water, and snacks, as well as continental breakfast.

Popular amenities for Cayce family-friendly rentals

Quick stats about vacation rentals that are family-friendly in Cayce

  • Total vacation rentals

    Explore 240 vacation rentals in Cayce

  • Nightly prices starting at

    Cayce vacation rentals start at ﺩ.ﺇ147 per night before taxes and fees

  • Verified guest reviews

    Over 14,690 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 100 rentals that welcome pets

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    150 properties have a dedicated workspace

  • Wi-Fi availability

    240 of Cayce vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Cayce rentals

  • 4.8 Average rating

    Cayce stays are highly rated by guests—averaging 4.8 out of 5!