
Guesthouse vacation rentals in Cape Coral
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Cape Coral
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Private guest house—minutes to the best beaches!
Experience the charm of Fort Myers in this quaint, private guest house located in the historic district. Perfectly situated near Fort Myers Beach (12 miles), Sanibel Island (16 miles), downtown (4 miles), some of the areas best restaurants (some even walking distance), grocery stores, & convenience stores. Easy access to Southwest Florida International Airport & FGCU. Uber and Lyft are easy access. The neighborhood is peaceful, safe, & walk friendly. Book now for a convenient and memorable stay.

Waterfront Hideaway
This picturesque Airbnb is a hidden gem nestled along a canal, one minute boat ride to the Caloosahatchee River. The living room, bathed in natural light is perfect for taking in the scenic views. The spacious bedroom has a king-size bed, ensuring a night of blissful rest. The full kitchen is equipped with all modern appliances. Close to Sanibel & Fort Myers Beach. Bring your boat & dock it on the seawall, ready to set sail whenever your heart desires. Book now - your coastal paradise awaits!

Perfect Place for your Vacations
This Guesthouse has everything you need for your vacation, it is central located, in a peaceful and safe neighborhood and have a very well distributed space. Its located few minutes from the Caloosahatche River and the beautiful beaches of the Gulf of Mexico, it includes bicycles, kayaks, umbrella, beach chairs, fishing rods and other items that will enhance your vacation. It is also very close to highly recommended restaurants, famous shops (walmart,Publix, McDonald) and other essential places.

Downtown Fort Myers Florida - Home Away From Home
Welcome to a peaceful studio apartment nestled in Fort Myers historical district of Edison Park just 500’ from the Edison & Ford Winter Estates just a short walk to downtown Fort Myers along Royal Palm tree lined McGregor Blvd. Visit the Downtown River District’s restaurants, bars, shops, Caloosa Sound Convention Center, theaters and minutes away from Sanibel, Captiva, Fort Myers Beach, golfing, multiple baseball parks (Twins & Red Sox), Southwest Florida International and Punta Gorda airports.

Hezekiah's 2 Story Guesthouse with Pool
Hezekiahs Guesthouse a perfect getaway in sunny SWFL! You will be staying in the guest house with a private entrance. This property has a living room and kitchenette downstairs and a spacious bedroom with master bathroom upstairs. This Airbnb is attached to our home. You will have access to the pool and our outside grill area. Complimentary coffee, water, soda and more.. Lots of nearby restaurants and shopping. Minutes away to Fort myers or Bonita beach, FGCU and RSW Airport and Hertz Arena.

Guest Suite Retreat
Enjoy a suite retreat at this centrally located lodging. Stay for business or pleasure just a short walk from beautiful, Royal Palm lined McGregor Blvd. Also, nearby are the tasty Mcgregor Cafe and Mcgregor Pizza. A 10 min drive will take you to historic downtown Ft. Myers with views of the Caloosahatchee River and lots of great restaurants and shopping. A 25 min drive in the other direction and you will be on lovely Ft. Myers Beach, experiencing all the fun and sun it has to offer. ***No Oven

Caloosahatchee Cottage - Waterfront, 5 min to D/T
Rest and unwind at the Caloosahatchee Cottage. This quaint guest cottage has sunset views that can’t be beat. Private space conveniently located just minutes from downtown Fort Myers. Full-sized bed, WiFi, TV with streaming services available, full bathroom, full size fridge and microwave (no kitchen). You’ll have access to the backyard and the dock (no swimming). You’ll share a walkway with the main house, but you’ll have plenty of privacy to rest and unwind. (Cottage is 160 sq ft total.)

Get Away to the Mango Cottage
Nestled on the outskirts of Historic downtown Fort Myers abides the Mango Cottage overlooking the Caloosahatchee River. The sunsets are amazing. You will enjoy the luxurious linens on the King sized bed to the relaxing patio it will delight the senses. You will be able to enjoy the 60" flat screen Smart TV! . The cottage is complete with Keurig coffee maker, toaster, microwave/convection oven and grill outside. We are minutes from restaurants and night life. This is a NON-SMOKING property.

Susie's Old Florida Cottage
Explore Pine Island & the Florida Gulf Coast from this retro 2-room cottage set in a pretty back yard. 45 min from Ft. Myers Beach/Sanibel. Wi-fi, A/C, kitchen, v small bathroom w/shower, 1 bedroom, cozy private deck, screened lanai. Perfect for 1 or 2. Avoid the motel feel & enjoy your privacy. Discounts for weekly/monthly bookings. No beaches on PIne Island, but enjoy kayaking, birding, biking, tennis, boating, & fishing. May 2023: Pine Island is still recovering from Hurricane Ian.

Adorable Cottage with Heated Pool -Jaccuzi - Sauna
Come and relax in this calm, stylish space located one acre property full of pines and fruit trees, with access to the House Heated Pool with Jacuzzi and the sauna. Modern design will make you feel comfortable. Close to Bonita, Ft.Myers, Lovers key and Sanibel beaches & fishing piers. Cottage is 12 miles away (19 km) from RSW airport, about 20 min of driving. We are happy to meet our guests, but also respect your privacy. Your comfort is our priority.

Downtown Cozy Cottage
This downtown guest house is a 5 minute walk to downtown Fort Myers. The guest house cottage has its own private entrance and is it’s own unit. There is another house on the property with a separate entrance. The only shared space is the laundry room. Enjoy citrus, avocado, and mango trees on the property. Plenty of parking in the back and your own private backyard area. New sound/impact resistant windows 2024. Photo ID required for booking.

Charming Carriage House in Historic Neighbourhood
This lovely carriage house backs onto the famous Edison Ford Estates making it a truly unique location- you really don’t have far to go to explore its beautiful gardens! Hit the Downtowns restaurants, bars and shops nestled within Art Deco architecture in stunning pastel colours for a real ‘Old Florida’ experience! DT is a 20 minute walk away or take advantage of the free trolley service from Nov-May 1. SWF airport 17 miles.
Popular amenities for Cape Coral guesthouse rentals
Family-friendly guest house rentals

Private guest house—minutes to the best beaches!

Cozy Escape!

Charming Carriage House in Historic Neighbourhood

Waterfront Hideaway

Carney Carriage House

Susie's Old Florida Cottage

Adorable & spacious efficiency w/ full kitchen

Pool modern
Guest house rentals with a patio

The Palmview Loft

Seahorse Studio

Adorable 1 BDRM first floor house in Bokeelia

Sleep over the water- Boathouse with Private Dock

Serene Studio Steps from the Water

Casa Del Franco

Luxury on the Lake

Adorable pool house near golf course
Guest house rentals with a washer and dryer

Arden's Garden

South Fort Myers close to FGCU and beaches

3 bedroom 2 bath Pool Front Guest house

Waterfront one/two bed in-law suite -gorgeous view

“Luxury Efficiency in San Carlos

Private & Newly Renovated Guest House!

Brand-New Guest Suite with Private Entrance

Florida Cottage with Pool, off McGregor Blvd.
Quick stats about guesthouse rentals in Cape Coral

Total vacation rentals
Explore 20 vacation rentals in Cape Coral

Nightly prices starting at
Cape Coral vacation rentals start at ﺩ.ﺇ147 per night before taxes and fees

Verified guest reviews
Over 750 verified reviews to help you choose

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
20 of Cape Coral vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Cape Coral rentals

4.9 Average rating
Cape Coral stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Cape Coral's top spots, include Sun Splash Family Waterpark, Four Mile Cove Ecological Preserve, and Marquee Coralwood 10
Destinations to explore
- Seminole Vacation rentals
- Central Florida Vacation rentals
- Miami Vacation rentals
- St Johns River Vacation rentals
- Orlando Vacation rentals
- Gold Coast Vacation rentals
- Miami Beach Vacation rentals
- Havana Vacation rentals
- Fort Lauderdale Vacation rentals
- Four Corners Vacation rentals
- Tampa Vacation rentals
- Kissimmee Vacation rentals
- Rentals with a kayak Cape Coral
- Fitness-friendly rentals Cape Coral
- Apartment rentals Cape Coral
- Rentals with breakfast Cape Coral
- Rentals with a patio Cape Coral
- Vacation home rentals Cape Coral
- Ski-in/ski-out rentals Cape Coral
- Rentals with pools Cape Coral
- Rentals with a washer and dryer Cape Coral
- Rentals with an accessible height toilet Cape Coral
- Family-friendly rentals Cape Coral
- Condo rentals Cape Coral
- Rentals with a fire pit Cape Coral
- Waterfront rentals Cape Coral
- Beach house rentals Cape Coral
- Rentals with lake access Cape Coral
- Pet-friendly rentals Cape Coral
- House rentals Cape Coral
- Villa rentals Cape Coral
- Rentals with beach access Cape Coral
- Townhouse rentals Cape Coral
- Rentals with a fireplace Cape Coral
- Rentals with a home theater Cape Coral
- Private suite rentals Cape Coral
- Rentals with a hot tub Cape Coral
- Rentals with an EV charger Cape Coral
- Rentals with outdoor seating Cape Coral
- Cottage rentals Cape Coral
- Beachfront rentals Cape Coral
- Guesthouse rentals Lee County
- Guesthouse rentals Florida
- Guesthouse rentals United States
- Naples Beach
- Captiva Island
- Caspersen Beach
- Manasota Key Beach
- Lovers Key Beach
- Englewood Beach
- Myakka River State Park
- Clam Pass Park
- Stump Pass Beach State Park
- Bonita National Golf & Country Club
- Heritage Bay Golf & Country Club
- Tigertail Beach
- Blind Pass Beach
- South Jetty Beach
- Esplanade Golf & Country Club of Naples
- Boca Grande Pass
- North Jetty Beach
- Gasparilla Island State Park
- Bunche Beach
- Edison & Ford Winter Estates
- Del Tura Golf & Country Club
- Talis Park Golf Club
- Warm Mineral Springs Park
- Manatee Park




