Vacation rentals in Byron

Kaleidoscope Flat 1 bd 1 mi to Mayo, Free Parking

Kaleidoscope Flat: This unique one bedroom has a style all its own! Enjoy beautiful wood floors, modern kitchen and bath with walk-in shower. Private entrance to a newly renovated second floor unit. The king bed has a memory foam mattress with adjustable bed frame for enhanced comfort and healing. Couch with pull-out full-size mattress. Child's pack and play available upon request. Private laundry in unit. Street parking in front. Free pass for Mayo clinic parking ramps. This saves $12 daily! 🙂

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

New! MN Comforts The Heart 4Bd/2Bth, 12min to Mayo

Welcome to MN Comforts The Heart! Are you here for work or leisure, or want to feel comforted after a Mayo appts? 12 min to Mayo Clinic, Wifi, work-station, ROKU/Smart TVs, and a fireplace in the family room. We offer a 2nd home feel. Near stores. Split-level, chill, and quiet, thoughtfully designed to cater to your needs, ensuring a comfortable, enjoyable stay. A blend of traditional & modern styling in a tranquil home, with fun opportunities for family & friends. Partially fenced backyard.

Unit 2365J | 2bd/2bth | Single-Family Home

Discover the perfect blend of comfort and convenience in our 2bd/2bth single-family home nestled in our safe, professionally managed community. This gem offers modern living with essentials like air conditioning, high-speed internet, and a fully equipped kitchen. Enjoy upscale amenities including a washer/dryer, smart-home technology, and a spacious 2-car garage. Plus, full access to a fitness center, outdoor pool, & BBQ area. All just a short drive from the Mayo Clinic. Your ideal home awaits!

Calm & Comfort | 12 Min to Mayo

- Enjoy a peaceful and private lower-level apartment 12 MINUTES TO MAYO -A spacious living room & bedroom, convenience station, plus a full bathroom with a relaxing shower -This stylish place has ample storage and Private entrance. Please note: your host lives on the upper level, but your space is completely private and secure, with host available if you need anything. - Whether you’re here for medical visits or a getaway, this home provides the perfect balance of comfort and convenience.

Home Sweet Minnesota

A few days or a few weeks away from home? Let us provide a comfortable and cozy get away in this turn of the century, two story home. Located in a quiet neighborhood with off-street parking, this property boasts large rooms, original hardwood floors and woodwork, a full kitchen, and laundry. The large, fenced in backyard, complete with playground and sandbox, makes this a child friendly space. The front porch and back patio provide outdoor room to grill, picnic, or just relax in a lawn chair.

Home Sweet Home

Welcome to a peaceful and centrally-located home just minutes from Mayo Clinic, Quarry Hill, Silver Lake, downtown Rochester, and more. This stay features a private kitchenette, private living room, and private work space, along with access to a laundry room upon request! At this stay you can count on cleanliness and care. I am promptly available for any needs that may arise. Perfect for Mayo Clinic patients or employees that live out of town and need a temporary, welcoming place to stay.

Oasis - Comfort & Serenity (Full house near Mayo)

*Discount for extended stays* Seeking a peaceful respite near Mayo Clinic in Rochester, MN? Look no further than "Oasis"–your ultimate home away from home. We offer 5 beds, 2 baths, & can accommodate up to 8 guests. Recharge in the workout & yoga meditation room, stay connected in the office area, & explore Rochester's attractions. Your dedicated host Peggy, a Mayo employee, will ensure a seamless/enjoyable stay. Book now & experience the perfect blend of comfort & serenity at Oasis.

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

Cozy, comfy 1 BR unit in triplex, 4 blocks to Mayo

This is a 1 BR unit that is in the lower level basement of a triplex (564 sq. ft). There are eight steps down to this apartment. It is bright and clean. This triplex is located in the Kutzky park neighborhood, a safe, quiet residential area. Free off street parking is available behind the house. The apartment has a complete kitchen with a stove, a refrigerator, plenty of dishes and pots and pans so you can make your own meals. There has an electric fireplace Wifi and a smart TV.

Woodland Retreat | 2 Acres | Close to Mayo

Escape to your spacious private suite in Rochester’s tranquil Weatherhill neighborhood. This beautifully appointed 1,300 ft² space features a relaxing jacuzzi style tub, full kitchen, laundry, and private entrance—all surrounded by two wooded acres for peace and privacy. Located just 10 minutes from downtown Rochester and Mayo Clinic, you’ll enjoy the perfect balance of comfort, convenience, and seclusion.

Cedar Loft is a tranquil retreat

If you are looking for a quiet retreat w/private entrance outside the city, you are home. Trees are outside every window with palpable serenity yet is still an easy ten-minute drive to downtown Rochester. This is a family-friendly place with crib and changing table. This is not a party house. It has a kitchenette so we will provide information to restaurants and grocery stores within 5 minutes.