Vacation rentals in Tower Grove South, St. Louis

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Top-rated vacation rentals in Tower Grove South, St. Louis

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

The image captures a charming street scene at sunset, with softly twilight colors illuminating the sky. Historic buildings line the street, and street lamps cast a warm glow, enhancing the inviting atmosphere of the neighborhood. Vehicles are parked along the cobbled road, suggesting a serene evening.

Home in Saint Charles

4.94 out of 5 average rating, 141 reviews

🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟

RachelRating, 5 stars2 weeks ago

The air b&b was my home away from home for 11 weeks, it felt like home instantly. Matt and his wife are very friendly and responsive. I loved the home, the space and the walks to the best downtown ST. Charles shops and restaurants. I was here for a law enforcement training and all agencies around stated this was the best and safest area to be staying, I couldn’t agree more. I would recommend this home over and over again. Thank you for making my stay a great experience especially from being away from home for so long!

Superhost

A staircase with white banisters and wooden steps leads to the upper level. The exposed antique brick wall provides historical character to the space. A woven area rug is positioned at the base of the stairs, complementing the warm wooden flooring.

Loft in Saint Charles

4.84 out of 5 average rating, 148 reviews

Main Street Historic Loft

DanielleRating, 5 stars1 month ago

This places was excellent. We enjoyed our stay. The place was cozy and comfortable, had what we needed. We were there on a Friday night…be warned it can get a little noisy outside so if that bothers you, then staying on a fairly busy street with lots of businesses probably isn’t for you. We weren’t bothered at all. Lots of great stores and restaurants on the same stretch of road. Definitely enjoyed our stay.

Top guest favorite

A modern kitchen is equipped with stainless steel appliances, including a gas stove and dishwasher. Open shelving showcases dishes, while a well-organized layout features several drawers. Natural light enters through small windows above the sink, and sleek countertops complete the space.

Home in South Hampton

5 out of 5 average rating, 41 reviews

Blair's Amazing House Sleeps 10 - 5 Beds - 2 Bath

HowardRating, 5 stars2 weeks ago

The house is well laid out, clean, and in a nice neighborhood. The location is convenient, safe, and quiet. The owner was responsive and flexible. While there is a garage, we never used it as there was always on-street parking right in front of the house. Everyone in our party thought it was a great choice!

Top guest favorite

The entrance features a set of double wooden doors framed by elegant columns and decorative planters. Lush greenery surrounds the steps, enhancing the inviting approach to the well-maintained exterior of the property.

Home in Tower Grove South

4.99 out of 5 average rating, 135 reviews

The Gateway Getaway

MoisesRating, 5 stars6 days ago

Everything was as described, the house is very spacious and our kids greatly enjoyed all the toys and books available — helped to keep them busy on a rainy day. Perfect location with short drive to downtown/main attractions but also a short walk to shops and restaurants

Superhost

A vintage-style living room is showcased, featuring a deep red and gold color palette. Ornately designed seating, including a parlor sofa and two matching chairs, surrounds a decorative coffee table. Natural light filters through sheer curtains, illuminating the space alongside a mounted television and an electric fireplace.

Apartment in St. Louis

5 out of 5 average rating, 4 reviews

Stay, Work & Play, 2bd w/office near Downtown

ChrisRating, 5 stars1 month ago

This was a clean, quiet and modern apartment. We loved the themed decor, the 1904 World’s Fair. Very charming, and we had everything we needed. Clean, well appointed. Lots of accoutrements. Seemed recently rehabbed/remodeled. Parking space included, though we used the ample street parking. Centrally located. Near Botanic Gardens and Tower Grove Park. Easy to get to downtown or other neighborhoods. We would definitely stay again if the opportunity arises. 🏆

Guest favorite

A fenced yard is featured, showcasing a blend of wooden panels in various tones. Flowering plants line the edge, with vibrant blooms among greenery. A putting green area is visible in the foreground, accompanied by a paved pathway leading to outdoor seating.

Home in St. Louis

4.89 out of 5 average rating, 207 reviews

Home away from Home St. Louis Cnty Ladue Schools

RaphaëlleRating, 5 stars3 weeks ago

Lisa was great! I needed a calm, peaceful and clean place for 2 weeks to recover from a surgery and her house was perfect. She was flexible with my arrival and departing time as I got updates from my surgeon and always worked it out with me, even last minute. There's a nice little park and neighborhood around and the house is very comfortable. Highly recommend!

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What guests are saying

Florissant's Old Town Inn (3BR)

5 out of 5 average rating, 3 reviews8 months ago

What a treasure we stumbled across! If you enjoy the vibes of an older home this one is for you! The neighborhood is very safe and amazing! The actual home has glass door knobs (if you know you know). The antique ceiling lights are amazing. They do have electronic locks, which are easy to access. The baths are updated, as well as the kitchen. Everything you could need was provided. We rented the entire place, (upstairs and down). My husband and I enjoying a weekend to watch some Cardinals baseball with our two adult children and a granddog. Sitting on the back patio watching the Koi fish could not have been more relaxing. Thanks for a great adventure. I hope to be able to visit this home in the future.

Home in Florissant

What guests are saying

Historic Haven by JZ Vacation Rentals

4.81 out of 5 average rating, 43 reviews3 weeks ago

Situated in a beautiful neighborhood and offers excellent walkability to numerous wonderful attractions, stores, and restaurants. The space itself is very spacious and features a nice kitchen and bathrooms. Whether you're looking for a comfortable base to explore the area or a relaxing place to unwind between activities, this is a great choice.

Townhouse in Central West End

What guests are saying

St. Charles Victorian Gem | Steps to Main Street

4.86 out of 5 average rating, 36 reviews1 month ago

St. Charles is always a favorite place of mine! This trip I was joined by four friends who had never been. Our stay was perfect! We all walked in the door with tons of ooohs and aaahs!! Garrett, our host was not only great at communicating but also very responsive. This home is truly a gem and I recommend it to everyone! You’re just a block to the heart of Main Street which has tons of great restaurants and shops! Our host provided great recommendations. But the home is perfect with lots of sleeping accommodations and bathrooms with a kitchen loaded with everything you could think of! The decor and charm of this home makes it one of my favorites of all time!

Home in Saint Charles

What guests are saying

Historic Cozy Family Home:4566 @Forest Park

4.68 out of 5 average rating, 19 reviews5 months ago

Location was great and felt very safe. Street parking was completely fine and all cars were safe. The back yard was great for dogs or kids. The house covered all the basics. The beds were really comfortable. Plenty of soap, shampoo, etc. in the large bathroom. Biggest complaint was lack of closet space. We certainly made do and it’s not a deal breaker but the bedroom that sleeps up to 4 has no closet and only one chest to sit luggage on. There’s also not much space to sit things on like charging stations for electronics on both sides of the beds, etc. The house isn’t “homey” per se since it’s a full time rental, but it is still very comfortable and extremely clean. The host is the most responsive host I’ve ever had and was very proactive letting us know about guests checking in and did help a ton when the upstairs neighbors were so loud we couldn’t sleep in. It’s an older home which explains the noise, and there are signs reminding everyone to please be polite and quiet which is nice.

Home in St. Louis

What guests are saying

Modern Luxury w/Saltwater Pool / ABODEbucks

4.82 out of 5 average rating, 66 reviews2 weeks ago

Had a wonderful stay at this Airbnb! The place was exactly as described—clean, comfortable, and thoughtfully decorated. The host was incredibly welcoming and responsive, making sure everything went smoothly. The location was perfect for exploring the area, and I truly felt at home during my stay. I would absolutely stay here again and highly recommend it to anyone looking for a relaxing and enjoyable visit! The work room was a plus.

Home in St. Louis

What guests are saying

Epic Pickleball Guest Retreat

4.97 out of 5 average rating, 32 reviews5 months ago

My husband and I spent a wonderful few nights at Renee’s pickleball getaway and it was a wonderful space for the two of us. The adjacent pb court was the real gem for us but we also enjoyed walking to local dining and shopping while we stayed. We are excited to stay here again!

Guesthouse in St. Louis

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Popular amenities for Tower Grove South, St. Louis vacation rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Stay near Tower Grove South, St. Louis's top sights

Missouri Botanical Garden432 locals recommend

Tower Grove Park263 locals recommend

Rooster144 locals recommend

Ted Drewes Frozen Custard139 locals recommend

The Shaved Duck81 locals recommend

Civil Life Brewing Co.62 locals recommend

Other great vacation rentals in Tower Grove South, St. Louis

Guest favorite

A living area is furnished with a tufted sofa and a wooden coffee table positioned on an area rug. Light flows through sheer curtains, illuminating the space. A television is mounted on the wall, and a small decorative piece sits on the console table.

Home in Caseyville

5 out of 5 average rating, 11 reviews

Bluebird Cottage

DanielRating, 5 stars1 month ago

This place was a delight. Incredibly clean and well-maintained property, fairly quiet and peaceful neighborhood, and a short drive from St. Louis made this a wonderful vacation stay.

Top guest favorite

A charming entrance features a white door framed by two tall windows. Lush, vibrant pink roses surround the front steps, creating a welcoming atmosphere. The house's exterior is complemented by navy shutters, enhancing the overall appealing look.

Home in Saint Charles

4.95 out of 5 average rating, 22 reviews

Home for friends or family

MissyRating, 5 stars4 weeks ago

I could not have found a better place to stay. Area was great, smooth check in, very clean home. Tony was excellent about responding.

Top guest favorite

The spacious basement features a large, power reclining sectional sofa with built-in cupholders and USB ports. An electric fireplace adds warmth to the area. The staircase leads to the upper levels, and the flooring is light wood, enhancing the open feel of the space.

Home in St. Louis

4.99 out of 5 average rating, 68 reviews

Spacious home with entertainment room and hot tub

MacRating, 5 stars2 weeks ago

Vicki & Nelson’s place was spectacular in every way. Our party of 4 adult males each commented how much they enjoyed our 4 night stay. Cleanliness was spectacular and furnishings were top notch. We have Ben getting together once a year for many years and this place is at the top of the list. We were even thinking about reasons to come back to Saint Louis so we could stay here again! It was that special.

Superhost

Home in Ballwin

4.83 out of 5 average rating, 24 reviews

Becky's Oasis-Sleeps 6/3 beds/Ballwin MO

BrannonRating, 5 stars4 months ago

Becky was very helpful and responsive. The house was convenient to the airport and nearby shopping.

Superhost

An open living area features exposed brick walls and modern furnishings. A comfortable sofa is positioned beside a wooden coffee table, with a dining area nearby that includes a round table and chairs. Bright overhead lighting illuminates the space, enhancing the contemporary design.

Home in St. Louis

4.92 out of 5 average rating, 220 reviews

Private Oasis w/hot tub

JacobRating, 5 stars1 week ago

Mark's house was very nice and clean with a delicious hot tub

Superhost

A spacious living area features a mounted television above a wooden media console. Light-colored walls and hardwood flooring create an airy ambiance. A comfortable sofa is accompanied by a coffee table, while a ceiling fan adds to the inviting atmosphere. The open layout leads to a well-equipped kitchen.

Home in Saint Ann

4.91 out of 5 average rating, 23 reviews

Charming quiet 2 bedroom duplex

QuentinRating, 5 stars2 weeks ago

Enjoyed my stay. Very lovely, nice friendly neighbors! Pictures looked just like the photos. Very responsive host, Always checks in. Will return again.

Guest favorite

Apartment in St. Louis

4.87 out of 5 average rating, 301 reviews

We do Italian STL style. Perfecto! Enjoy our NBHD!

AmyRating, 5 stars3 weeks ago

This was the perfect spot… peaceful, safe, and quiet neighborhood within walking distance of so many homey, welcoming local restaurants! It was lovely to be able to walk everywhere to dinner and not have to drive. And it was within easy driving distance of all the tourist stuff we wanted to do. The suite had everything we needed and we especially appreciated the labels on the light switches! Very clean and comfy. Would 100% stay here again.

Top guest favorite