Hotels in St. Charles County

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Top-rated hotels in St. Charles County

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Guest favorite

The studio features high ceilings with exposed ductwork and charming Edison bulb lighting. A spacious bed is visible alongside a comfortable seating area that includes a sectional sofa. Large, industrial-style windows allow natural light to illuminate the minimalist décor and furnishings.

Hotel room in St. Louis

4.88 out of 5 average rating, 86 reviews

Chic Ultramodern Studio Loft w/ Designer Features

The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, a spacious walk-in closet, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

A spacious bedroom features a large bed with crisp white linens and a textured accent wall in deep blue. A flat-screen television is mounted on the wall, and a desk with a chair is positioned nearby. Natural light enters through a window adorned with simple curtains.

Hotel room in St. Louis

4.74 out of 5 average rating, 132 reviews

The West End by Cortex, Forest Park, BJC & Zoo

Welcome to The West End, your ideal retreat in the heart of the Central West End! Just steps away from charming attractions like forest park. Great amenities are: - Fast and stable fiber internet connection - Communal kitchen with 2 sets of range, ovens, fridges, microwaves, and dishwashers. - Complimentary coffee - Secured Gated Parking $10/Night - Hot Tub - Great patio space with seating and a gas grill - Complimentary Netflix, Hulu, Disney+, and ESPN+, where available and local TV channel

A well-lit guest room features two double beds dressed in white linens. A bedside table holds a small vase with fresh flowers. The wall behind the beds is painted in soft blue, complemented by a framed floral artwork.

Hotel room in Chesterfield

4.67 out of 5 average rating, 3 reviews

St. Louis Family Break! 2 Spacious Units! Pool!

Situated in the suburban city of Chesterfield, this hotel offers an ideal location for exploring the area's attractions and provides an excellent base for visits to St. Louis. It is well-placed for shopping breaks, with Chesterfield Malls and St. Louis Premium Outlets nearby. At the same time, those seeking active pursuits may enjoy the Hidden Valley Ski Resort. Several family day trip options, including the Magic House, Missouri Botanical Garden, and Six Flags St. Louis, can be found nearby.

An outdoor courtyard area is illuminated by warm lighting, featuring a decorative lantern on a stone surface. Surrounding potted plants add greenery, while stone and brick elements create a welcoming entrance to the nearby hotel building.

Hotel room in Earth City

4.44 out of 5 average rating, 41 reviews

Perfect Getaway Near The Airport | Free Shuttle

The Holiday Inn St. Louis Airport West Earth City is just 6 miles from the St. Louis-Lambert International Airport and offers a complimentary airport shuttle. Conveniently located near downtown St. Louis and Historic St. Charles, travelers and guests will be in an ideal location for shopping, dining, and entertainment. Visitors can dine or enjoy cocktails at Elements, our on-site restaurant and bar. A well-equipped fitness center and a relaxing heated indoor pool complete your stay.

Superhost

Hotel room in St. Louis

4.88 out of 5 average rating, 8 reviews

Near Central West End | Free Breakfast + Pool. Bar

Stay smart, stylish, and sustainable in the heart of St. Louis Midtown. Just steps from Forest Park, SLU, and the Grand Center Arts District, Element St. Louis Midtown features sleek, apartment-style suites with full kitchens and eco-conscious touches. Unwind in the indoor pool, sip cocktails at the on-site bar, and start your day with free hot breakfast. With EV charging, a fitness center, and walkable hotspots nearby, this stay blends comfort, convenience, and a touch of luxury.

A spacious sleeping area features multiple wooden bunk beds with red bedding, surrounded by exposed brick walls and wooden beams above. A cozy seating arrangement includes a casual sofa, while light flows in through several windows, enhancing the room's rustic charm.

Hotel room in St. Louis

4.75 out of 5 average rating, 4 reviews

Huge Penthouse & Gameroom- Big Group Stay

The Penthouse Suite is ideal for a large group stay! This sprawling 2,000 Sqft open studio-style layout sleeps 20+ Guests. Featuring 1 private bedroom offering a King-size bed, 6 Queen bunks, 2 reg Queens, 2 Full, & 2 Twins. A full kitchen and a bathroom w/ a shower. Located on the top (3rd) floor, providing great sunset & city views. ***Guests have shared access to an expansive and eclectic GameRoom with another full kitchen, bathroom, TVs, pool table, ping pong, and darts.

Superhost

A well-arranged guest room features two spacious queen-sized beds with soft linens and olive green bedspreads. The room is accented by a textured light gray carpet and a large window with solid curtains. A cozy armchair sits beside a bedside table, enhancing the inviting space.

Hotel room in Cottleville

5 out of 5 average rating, 3 reviews

Double Queen Room 203

Room 203 features two queen-sized beds Oak Street Inn & Lounge, 8 Room Boutique hotel situated in the bustling center of downtown Cottleville. Oak Street Inn & Lounge will offer an elegant restaurant and craft cocktail lounge on the ground floor Indulge in room service from Pink Willow Cafe, or dine in! Come up to the rooftop patio on the third level for a cocktails, small bites and breathtaking views of Cottleville. Look for our Hidden Gem the Speakeasy in the lower level!

The exterior of the AC Hotel Central West End is displayed, featuring a modern six-story building with brick cladding and large windows. The entryway is accented with wooden slats, and a welcoming glass facade reflects the evening sky.

Hotel room in St. Louis

4.63 out of 5 average rating, 27 reviews

Walk to Forest Park + On-site Restaurant & Bar

Stay steps from Forest Park and the best of Central West End at AC Hotel St. Louis. With sleek European-inspired design, a vibrant lobby bar, and walkable access to top restaurants, museums, and nightlife, you’re perfectly placed for STL adventures. Grab a crafted cocktail, hit the 24/7 gym, or explore iconic spots like the Zoo and Art Museum—all just minutes away. Whether you're here for business, culture, or Cardinals baseball, this stay keeps you close to it all.

A spacious living area featuring a comfortable sofa and a coffee table. A desk with an ergonomic chair is positioned nearby, and a dresser is visible next to the 43-inch television. Natural light filters through the window treatments, illuminating the overall layout.

Hotel room in St. Louis

Downtown Studio l Swimming. Gym. Free Breakfast.

Welcome to Residence Inn by Marriott St. Louis Downtown, nestled in Missouri! We provide a great location in downtown St. Louis, spacious lodgings, and great facilities such as a pool and fitness center. Enjoy a daily breakfast buffet - on us! Then, head out to one of the nearby attractions, such as The Gateway Arch and St. Louis Zoo. ✔ Pool ✔ Fitness center ✔ Free breakfast ✔ Pet-friendly ✔ Indoor and outdoor fireplaces ✔ Mini-market ✔ Downtown location

Hotel room in St. Louis

New place to stay

Maison Lafayette | Boutique Hotel | Park Ave. Room

Maison Lafayette Boutique Hotel is a restored historic mansion in the heart of Lafayette Square, one of St. Louis’s most iconic neighborhoods. Formerly a traditional bed and breakfast, the property now offers private guest rooms with ensuite bathrooms, elegant shared spaces, and curated amenities. Guests enjoy a refined, quiet stay minutes from downtown, Lafayette Park, dining, and major attractions.

A spacious bedroom features a large bed with crisp white linens. Two windows allow natural light to brighten the room, complemented by decorative lamps on either side. A vintage-style fireplace and a circular mirror add character to the space, while a soft area rug enhances comfort.

Hotel room in Saint Charles

4.8 out of 5 average rating, 10 reviews

Modern Boutique Stay w/ Plush King Bed- Hare Suite

The Hare Suite at the Divine Otter Hotel offers a stylish 1-bedroom escape, sleeping up to 2 guests. Enjoy upscale furnishings, a modern design, and a spacious full bathroom with plenty of natural light. Located in the heart of Historic Main Street Saint Charles, you’ll be steps away from shops, dining, and more. This impressive suite is the perfect blend of comfort and location!

Top guest favorite

The exterior of a renovated Victorian house features a light yellow facade adorned with decorative trim and five tall windows. Colorful flowers and shrubs accent a well-maintained garden, while a set of steps leads to a welcoming front door, framed by two planters.

Hotel room in St. Louis

5 out of 5 average rating, 36 reviews

Lafayette Square Inn - Burgundy Room

Lafayette square has the largest collection of renovated victorian houses in America and this is one of them. Dating to 1876, this historic home offers quality amenities. We are located near: America's Center Convention Complex - 2 Miles Bush stadium - 1.5 Miles Stifel Theatre - 1.4 miles Gateway Arch - 2.1 Mi Enterprise Center - 1.2 Mi Delmar Hall - 7 Mi