
Vacation rentals in Santa Panagia
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Santa Panagia
Guests agree: these stays are highly rated for location, cleanliness, and more.

Maisonette, 14 San Paolo
Maisonette San Paolo 14, an extremely elegant suite, is located in a historic 17th-century building adjacent to the Temple of Apollo, following a meticulous renovation focused on comfort and design. As soon as you enter, you are enveloped by a positive energy that conveys serenity and harmony, perfect for relaxing. Equipped with a kitchen, an en-suite bedroom, and a stylish outdoor patio for enjoying unforgettable moments. The intimate atmosphere of this residence makes it ideal for couples and for the most discerning guests.
LocationValueAmenities
5.0 out of 5 average rating, 20 reviews
Ortigia 10, Stylish Flat with stunning Sea View
This elegant and bright 90 sqm apartment is located on the 2nd floor of an ancient building, equipped with an elevator. It enjoys one of the most beautiful views of the sea and the sunsets of Ortigia. Furnished with taste and attention to details, the flat has a living room and a large double bedroom with balconies overlooking "La Darsena". The apartment has a second bedroom with a French bed and an en-suite bathroom, a second bathroom and a full-equipped kitchen with dishwasher and closet.
ValueLocationBathroom
4.97 out of 5 average rating, 116 reviews
The Loggia of Arethusa
La Loggia di Aretusa is a unique experience. You will experience your vacation within the myth of the nymph Arethusa and the Fountain named after her, stunned by the scent of the sea mixed with that of magnolia, enjoying the extraordinary view of the Port of Ortigia, the suggestion of the sunset, the calm of dawn, in a more than central unique location. You can sunbathe from your veranda, have breakfast or an aperitif with those you love and to whom you will give a unique experience.
ValueLocationAccuracy
4.97 out of 5 average rating, 173 reviews
Victor' apartment
Victor apartment is a cozy, bright apartment, finished with care and elegance in the heart of the new city, a few steps from the services. It has a large living room with separate kitchen and double sofa bed. Spacious double bedroom with wardrobe. The bathroom is very comfortable with a shower. The apartment offers free Wi-Fi, air conditioning, TV and washing machine and free parking adjacent to the property's internal garden. Have fun with the whole family in this stylish place.
FamilyLocationBathroom
4.89 out of 5 average rating, 56 reviews
Light and Relaxation: Large Open Space on the Garden
Located in a private wing of the villa with a separate entrance, this 95-square-meter open space combines refinement and modernity. The large windows flood the rooms with natural light, while the decor naturally defines the different areas. A perfect balance between design, comfort and nature: the spaces blend harmoniously with the garden, creating relaxation and privacy. For safety and comfort reasons, the property only accommodates children aged 10 and over.
LocationPoolDecor
4.88 out of 5 average rating, 8 reviews
Casa Sabir, chic apartment by the Ortigia market
Casa Sabir is an elegant early 1900’s lodging that opens out on to the colors and scents of the historic market of the island of Ortigia in Syracuse. Sitting on the balconies you will enjoy the privilege to capture the lively atmosphere evoked by the calls of the vendors of fresh fish and vegetables and to immerse yourself in the aromas of spices. Let you regenerate under the mediterranean light and experience the most authentic and intense soul of Sicily.
LocationValueNearby
4.92 out of 5 average rating, 136 reviews
Agàpe Ortigia
Agàpe Ortigia is an accommodation created with Love in the magical island of Ortigia, in the historic center, a stone's throw from the Duomo and the major sites of interest. The independent room is large and spacious, has a double bed, TV, free Wi-Fi, tea and coffee corner, but the peculiarity of this accommodation apart from the furnishings is the bathroom which, in addition to having the main amenities, offers a large sunken tub where you can relax.
ValueLocationNearby
4.95 out of 5 average rating, 202 reviews
Casa Salgiò
Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.
FamilyValueCondition
4.64 out of 5 average rating, 45 reviews
Elegant apartment in the heart of Syracuse.
Casa Carabelli33 is an elegant apartment in the heart of Syracuse, just steps from the Greek Theatre, Ortigia, and the train station. Bright and spacious, it features 3 double bedrooms, each with a private en-suite bathroom, offering maximum comfort and privacy. A cozy living room, modern kitchen, and outdoor balcony provide perfect spaces to relax. Ideal for families or groups seeking style and convenience.
LocationValueAmenities
4.97 out of 5 average rating, 36 reviews
Comfortable apartment with reserved parking space
Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.
FamilyValueSleep quality
4.96 out of 5 average rating, 69 reviews
ltm greenhouse historic home
The ancient villa is located on the rock crag in the center of the Latomia dei Cappuccini. Just restored, it appears as a place of incredible charm and allure. Bounded by white stone walls of Syracuse and surrounded by lush vegetation, today it offers a corner of unique beauty and harmony away from any urban contamination yet immersed in the center of the ancient city.
FamilyLocationQuiet
5.0 out of 5 average rating, 44 reviews
[Elegant] DreamSuite - 300m from Ortigia
-Quality furnishings, comfortable bed and sofa bed - Parking spaces in the area -300m from the historic center - Surrounding area full of bars and restaurants - The house consists of a living area, equipped kitchen and a bedroom - 2 bathrooms with shower - 2 smart TVs - Free Wi-Fi - Fully air-conditioned and soundproofed environment
ValueFamilyQuiet
4.95 out of 5 average rating, 140 reviewsPopular amenities for Santa Panagia vacation rentals
Other great vacation rentals in Santa Panagia

The Pearl of the South
LocationValueOutdoor spaces
4.79 out of 5 average rating, 38 reviews
Pi Greco/ Walk to Ortigia/ Easy parking
LocationNearbyGetting around
5.0 out of 5 average rating, 7 reviews
Casa Sirokos
FamilyValueSleep quality
4.93 out of 5 average rating, 56 reviews
Attico Malgari, stupendo terrazzo fronte Ortigia
LocationFamilyComfort
4.89 out of 5 average rating, 46 reviews
Prime Ortigia |Soaring Ceilings Designer Interiors
FamilyValueAir conditioning
5.0 out of 5 average rating, 20 reviews
Casa Sbarcadero
FamilyLocationAccess
5.0 out of 5 average rating, 46 reviews
House on the latomia with free private parking
FamilyValueQuiet
4.98 out of 5 average rating, 81 reviews
Sweet blue Plemmirio
LocationBathroomNearby
4.98 out of 5 average rating, 42 reviewsDestinations to explore
- Naples Vacation rentals
- Metropolitan City of Palermo Vacation rentals
- Bari Vacation rentals
- Catania Vacation rentals
- Sorrento Vacation rentals
- Valletta Vacation rentals
- Sliema Vacation rentals
- Taormina Vacation rentals
- Positano Vacation rentals
- Monopoli Vacation rentals
- San Giljan Vacation rentals
- Amalfi Vacation rentals
- Fontane Bianche Beach
- Etna Park
- Calamosche Beach
- Castello Ursino
- Piano Provenzana
- Teatro Massimo Bellini
- Villa Bellini
- Oasi Del Gelsomineto
- Castello Maniace
- Greek Theatre of Syracuse
- Castello di Donnafugata
- Nature reserve of Vendicari
- Fishmarket
- Museo Emilio Greco
- Etnaland
- Spiaggia Vendicari
- Isola delle Correnti
- Sampieri Beach
- Aci Trezza
- Temple of Apollo
- Necropolis of Pantalica
- Noto Antica
- Noto Cathedral
- Fondachello Village





