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Vacation rentals in Santa Panagia

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Top-rated vacation rentals in Santa Panagia

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Condo in Syracuse
4.99 out of 5 average rating, 359 reviews

Sea-View Loft. Elegant & Bright Old Town Retreat

Experience the timeless charm of Ortigia from this elegant 80 m² sea-view apartment. Perfect for couples, families, or small groups, Suite 18 blends authentic Sicilian character with modern comfort, just steps from the island’s iconic landmarks. Wake up to breathtaking harbour views from your private balcony, relax in the bright open-plan living area, and enjoy a fully equipped kitchen, a peaceful bedroom, and two modern bathrooms. Amenities include fast WiFi, A/C, heating and lift access.

Top guest favorite
A spacious living area is highlighted by a distinctive pink staircase that ascends to the upper level. Large windows allow natural light to illuminate the room, while a modern dining table with black chairs complements the decorative tiled flooring. A comfortable gray sofa is adorned with a pink pillow.
Condo in Syracuse
4.96 out of 5 average rating, 96 reviews

Suite Pink - Ortigia

Suite di 65 mq al secondo piano di un palazzo storico zona mercato. Una dimora da terra a cielo recuperata dal passato, per un ambiente dalle suggestioni antiche e contemporanee. Un trionfo di luce e benessere per un soggiorno indimenticabile. La casa è stata oggetto di un accurato intervento di recupero, gli interni sono oggi la combinazione di un profondo passato e dei ricercati interventi eseguiti i quali contribuiscono a creare un ambiente ricco di suggestioni antiche e contemporanee.

Guest favorite
A modern kitchen features a large dining table set with colorful plates. A prominent clock on the wall enhances the space, while yellow cabinets and grey countertops provide a contemporary touch. Ample natural light enters through the window, illuminating the room.
Apartment in Syracuse
4.96 out of 5 average rating, 206 reviews

Brand new apartment with patio across Ortigia

Fully renovated modern apartment in proximity of Ortigia (6 mins walk) with free parking. With its three ensuite double bedrooms, the apartment can accommodate up to 6 people. All the rooms have aircon and 32' smart TV as same as the living room equipped with a 50' smart TV, a cozy couch and a few armchairs. A fully equipped kitchen and a patio to enjoy a glass of wine around a wooden table with your family and friends. Never wait around as you can check yourself in with the access code!

Top guest favorite
Home in Syracuse
4.97 out of 5 average rating, 37 reviews

Casa Santini Ortigia, 3 Bed 3 Bath, 1 min to Beach

On a quiet road a few steps away from the sea and Cala Rossa beach, this luminous independent 3 beds and 3 bathrooms townhouse, has been designed to make your holiday in Ortigia unforgettable. "CASA SANTINI" is the product of our family's love for Ortigia and the vision of our local Architect Ignazio. The house has been fully renovated with meticulous attention to details, keeping the old features and adding all comforts and modern elements to create an elegant and calming space.

Top guest favorite
A serene pool area is surrounded by lush greenery, featuring a crystal-clear swimming pool. Comfortable loungers and a white umbrella are positioned nearby. A decorative stone bench displays two patterned pillows, adding a subtle touch to the inviting outdoor space.
Vacation home in Syracuse
4.94 out of 5 average rating, 48 reviews

Casa Sirokos

Casa Sirokos is a detached villa facing the pool, surrounded by the greenery of the most scenic residential neighborhood in Syracuse. It features local architecture that blends with large outdoor spaces and gardens typical of the Sicilian countryside. The cottage is one of two independent accommodations that are part of this property, which also offers an apartment located on the second floor of an ancient manor house. The sophisticated and relaxing atmosphere sets us apart!

Superhost
A spacious sleeping area features a large bed with soft green accents and warm wooden flooring. A comfortable chair is positioned beside the bed, and a round rug with leaf patterns adds a touch of nature. Natural light filters in through large windows covered with shades.
Condo in Syracuse
4.83 out of 5 average rating, 6 reviews

Light and Relaxation: Large Open Space on the Garden

Located in a private wing of the villa with a separate entrance, this 95-square-meter open space combines refinement and modernity. The large windows flood the rooms with natural light, while the decor naturally defines the different areas. A perfect balance between design, comfort and nature: the spaces blend harmoniously with the garden, creating relaxation and privacy. For safety and comfort reasons, the property only accommodates children aged 10 and over.

Top guest favorite
A private terrace features colorful loungers positioned around a round table. Green plants add a touch of nature, enhancing the space. The backdrop includes a clear blue sky and glimpses of neighboring buildings, creating a relaxed atmosphere for outdoor enjoyment.
Apartment in Syracuse
4.96 out of 5 average rating, 23 reviews

Aglaia apartment Ortigia Island terrace

Nel centro autentico dell'isola d'Ortigia, nell'antico quartiere dei pescatori della Graziella, a due passi dallo storico mercato , l'appartamento è in una zona interamente pedonale dove il tempo sembra non essere passato. La tranquillità delle stradine che si intersecano è tipica di questo quartiere dell'isola di Ortigia. A pochi metri si raggiunge il duomo e le principali meraviglie della città. Poco distante l'unico parcheggio dell'isola pedonale.

Superhost
A modern living area is presented, featuring a flat-screen television mounted on a light-colored wall unit. A dining table with four black chairs is positioned nearby, and a dark area rug is laid on the tiled floor. Soft lighting is provided by exposed bulbs.
Apartment in Syracuse
4.69 out of 5 average rating, 39 reviews

Casa Salgiò

Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.

Guest favorite
A softly lit hallway features a framed floral painting above a white console table. A green glass lamp and a small potted plant are placed on the table, while another plant sits nearby on the floor, contributing to a calming atmosphere.
Condo in Syracuse
4.97 out of 5 average rating, 62 reviews

Comfortable apartment with reserved parking space

Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.

Top guest favorite
Home in Plemmirio
4.98 out of 5 average rating, 114 reviews

Casa Francesca

Detached house directly located on the rocks in a private condominium context in the protected marine area of Plemmirio, in the seaside area of the beautiful city of Syracuse. Simply and tastefully furnished, with an unparalleled 360° view of the sea and a large terrace shaded by reeds where you can experience moments of relaxation and conviviality pieds dans l'eau.

Guest favorite
The spacious terrace is furnished with a wooden seating area, featuring a lounge chair and a table. Potted plants are placed around the area, and a light canopy provides shade. A peaceful view of the rooftops is visible against a soft evening sky.
Condo in Syracuse
4.91 out of 5 average rating, 101 reviews

Lovely apartment in the heart of Ortigia

In the heart of Giudecca, a stone's throw from the cathedral and the sea, on one of the most photographed streets of Ortigia. Elegant apartment, newly renovated, equipped with all the necessary amenities for your stay. Its strategic location on the island offers its guests an excellent central location but at the same time a quiet and peaceful stay.

Guest favorite
A spacious living area is showcased, featuring a comfortable sofa with green accent pillows. A sleek television is mounted on a wooden console, while a dining table is visible in the background. Decorative plants enhance the room's atmosphere.
Home in Syracuse
4.95 out of 5 average rating, 131 reviews

[Elegant] DreamSuite - 300m from Ortigia

-Quality furnishings, comfortable bed and sofa bed - Parking spaces in the area -300m from the historic center - Surrounding area full of bars and restaurants - The house consists of a living area, equipped kitchen and a bedroom - 2 bathrooms with shower - 2 smart TVs - Free Wi-Fi - Fully air-conditioned and soundproofed environment

Popular amenities for Santa Panagia vacation rentals