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Vacation rentals in Santa Panagia

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Top-rated vacation rentals in Santa Panagia

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Noto
4.96 out of 5 average rating, 54 reviews

Penthouse Lady Packard

Lady Packard’s Penthouse just had a glow up!✨ A stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.

Guest favorite
An outdoor balcony features a small wooden table paired with two white chairs. Potted plants add greenery, while the view showcases nearby buildings against a clear blue sky. Natural light brightens the space, creating a refreshing atmosphere for relaxation.
Apartment in Syracuse
4.96 out of 5 average rating, 272 reviews

One step to Ortigia! Bicycles & Balcony

Bright and stylish renovated flat just steps from the city center and Ortigia—you can walk to all the must-see spots with ease. Cozy and welcoming, it’s the perfect home base for your holiday in Sicily! ☀️ Sunny balcony for relaxing moments en plein air 🚲 FREE bicycles available throughout your entire stay 🚗 Hassle-free street parking – and it’s free 24/7! We also have two more apartments in the same building—check out my profile to discover them and read our glowing 5-star reviews!

Guest favorite
A serene pool area is surrounded by lush greenery, featuring a crystal-clear swimming pool. Comfortable loungers and a white umbrella are positioned nearby. A decorative stone bench displays two patterned pillows, adding a subtle touch to the inviting outdoor space.
Vacation home in Syracuse
4.94 out of 5 average rating, 47 reviews

Casa Sirokos

Casa Sirokos is a detached villa facing the pool, surrounded by the greenery of the most scenic residential neighborhood in Syracuse. It features local architecture that blends with large outdoor spaces and gardens typical of the Sicilian countryside. The cottage is one of two independent accommodations that are part of this property, which also offers an apartment located on the second floor of an ancient manor house. The sophisticated and relaxing atmosphere sets us apart!

Superhost
A spacious sleeping area features a large bed with soft green accents and warm wooden flooring. A comfortable chair is positioned beside the bed, and a round rug with leaf patterns adds a touch of nature. Natural light filters in through large windows covered with shades.
Condo in Syracuse
4.83 out of 5 average rating, 6 reviews

Light and Relaxation: Large Open Space on the Garden

Located in a private wing of the villa with a separate entrance, this 95-square-meter open space combines refinement and modernity. The large windows flood the rooms with natural light, while the decor naturally defines the different areas. A perfect balance between design, comfort and nature: the spaces blend harmoniously with the garden, creating relaxation and privacy. For safety and comfort reasons, the property only accommodates children aged 10 and over.

Top guest favorite
The spacious sleeping area features a large white bed positioned against an arched stone wall. Soft lighting highlights the texture of the stones, while decorative elements add a touch of charm. A woven rug lies at the foot of the bed, contributing to the room's cozy appeal.
Home in Syracuse
4.94 out of 5 average rating, 191 reviews

Agàpe Ortigia

Agàpe Ortigia is an accommodation created with Love in the magical island of Ortigia, in the historic center, a stone's throw from the Duomo and the major sites of interest. The independent room is large and spacious, has a double bed, TV, free Wi-Fi, tea and coffee corner, but the peculiarity of this accommodation apart from the furnishings is the bathroom which, in addition to having the main amenities, offers a large sunken tub where you can relax.

Superhost
A modern living area is presented, featuring a flat-screen television mounted on a light-colored wall unit. A dining table with four black chairs is positioned nearby, and a dark area rug is laid on the tiled floor. Soft lighting is provided by exposed bulbs.
Apartment in Syracuse
4.71 out of 5 average rating, 38 reviews

Casa Salgiò

Cozy and modern apartment on the outskirts of Syracuse, just a 10-minute drive from the historic center and in a well-served area. The apartment, completely renovated, consists of a living area with a double sofa bed, an equipped kitchenette, a bedroom, a small room with a bed, a bathroom with a shower, a storage room and a laundry area. The living room and bedroom overlook a veranda from which you can see glimpses of the sea and Mount Etna.

Top guest favorite
Apartment in Syracuse
5.0 out of 5 average rating, 41 reviews

Casa Sbarcadero

Casa Sbarcadero is just a 6-minute walk from the historic center of the island of Ortigia and about 20 minutes from the Neapolis archaeological area. The apartment offers access to the public solarium below, perfect for relaxing. The apartment consists of three bright rooms overlooking the small port, two bathrooms, a spacious living room and a well-equipped kitchen. The bus and train station is a 15-minute walk away.

Guest favorite
Apartment in Syracuse
4.93 out of 5 average rating, 45 reviews

Regine luxury apartment by Dimore in Sicily

CIN:IT089017C25PMCIRC7 CIR:19089017C221260 Welcome to Regine Luxury Apartment, an exclusive retreat in the heart of Ortigia, Syracuse. This elegant 4-bedroom, 5-bathroom apartment, located in a historic building, offers spectacular sea views from its private terrace. Enjoy the fully equipped kitchen and proximity to local attractions. Ideal for families and groups, it offers an unforgettable Sicilian experience.

Guest favorite
The bedroom features a spacious bed adorned with light-colored linens and neatly arranged towels. Large windows allow for ample natural light and offer a view of the harbor and surrounding boats. Soft curtains frame the windows, enhancing the relaxing atmosphere.
Home in Syracuse
4.89 out of 5 average rating, 129 reviews

Eos sea view apartment & private Parking

Eos Sea View Apartment on the newly inaugurated downtown waterfront! Enjoy breathtaking views of the small port and Ortigia: admire sailboats and sea sunrises straight from your bed or over breakfast. Step outside to a long seafront promenade, a beach, and sea access. Enjoy the stylish design, relax on the equipped patio with tables and chairs, and love the ultimate perk: free parking in a private courtyard!

Guest favorite
Apartment in Syracuse
5.0 out of 5 average rating, 12 reviews

Sky Rooftop Ortigia

In the vibrant heart of Ortigia, just a few steps from the touristic port, this charming home welcomes you in a truly unbeatable location. Here, you can immerse yourself in the authentic atmosphere of the historic center, surrounded by picturesque alleys, local shops, and traditional restaurants, with the sea always within sight. The apartment is located on the third floor and is accessible by stairs only.

Guest favorite
A softly lit hallway features a framed floral painting above a white console table. A green glass lamp and a small potted plant are placed on the table, while another plant sits nearby on the floor, contributing to a calming atmosphere.
Condo in Syracuse
4.97 out of 5 average rating, 62 reviews

Comfortable apartment with reserved parking space

Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.

Top guest favorite
Home in Plemmirio
4.98 out of 5 average rating, 114 reviews

Casa Francesca

Detached house directly located on the rocks in a private condominium context in the protected marine area of Plemmirio, in the seaside area of the beautiful city of Syracuse. Simply and tastefully furnished, with an unparalleled 360° view of the sea and a large terrace shaded by reeds where you can experience moments of relaxation and conviviality pieds dans l'eau.

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