Vacation rentals in Santa Maria

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Top-rated vacation rentals in Santa Maria

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A modern kitchen features a spacious island with three high-backed bar stools. The countertops are light-colored, complemented by dark cabinetry and a decorative backsplash. Stainless steel appliances are visible, and a small tray with flowers is placed on the island.
Condo in Mercedes
4.95 out of 5 average rating, 150 reviews

Quiet huge 4 bed condo 2 miles by the Outlets!

Centrally located in the Rio Grande Valley. This quiet 3 bedroom condominium is a shoppers paradise only two miles away from the Mercedes Outlets! Travel into the most tourist friendly border city in Mexico, the city of Progreso, only 10 miles away! Head to the beach at South Padre Island, about 50 miles away. Be mesmerized by Elon's Space X at Boca Chica Beach 67 miles away! Level 2 charging outlet (nema 14-50R) reserved for you, bring your own EV charger. Unlimited free parking on premises.

Top guest favorite
A comfortable living area is presented with a brown leather sofa and a patterned area rug. A coffee table made of woven material is positioned in the center. A 65" HDTV is mounted on the wall, enhancing the cozy ambiance. Natural light filters through the windows, complemented by curtains.
Condo in Harlingen
4.94 out of 5 average rating, 121 reviews

BOHO chic 2b w/suites 4 min f Airport and Hospital

Multiple listings at the same location! Perfect for families or company events. Come relax in this calm, stylish space. 65" HDTV with Roku. Each bedroom has it's own TV and private full bathroom. Gated, keyless entry. Fully stocked laundry with washer and dryer. Backyard with barbecue grill. Great location minutes away from Valley International Airport and Hospitals. 40 min from South Padre Island and McAllen, 20 min from Brownsville. SpaceX, shopping, dining, trails, and birding centers nearby.

Top guest favorite
A small wooden pier extends over calm waters, flanked by trees and palmettos. Two white chairs are positioned beside softly glowing lamps, providing gentle illumination as the sun sets in the distance, creating a serene ambiance.
Guesthouse in McAllen
4.97 out of 5 average rating, 301 reviews

Rm 101 Ethereal @ PeculiarNest Lake Conception

A beautiful lakefront one-bedroom cabin overlooking a 7-acre private lake and situated inside a one acre permaculture food forest/garden. It is a haven for birders and naturalists as well as the wildlife we share the space with. Enjoy feeding the roaming peacocks, viewing the sunrise and sunset, and sipping coffee on the private porch or pier. Additional units (apartment style&private rooms) are available to meet our guests' varying needs. Please check out my other listings in the profile.

Guest favorite
Apartment in Harlingen
4.92 out of 5 average rating, 110 reviews

Sage House-$0 cleaning fee! Peaceful, chic.

Stylish,5 min from airport! Sage house embodies relax and zen. Creature comforts include 85 inch in the main lounge, European Spa Toiletries, TIGI line of hair products. Premium Keurig machine stocked with your faves! Hybrid beds w/1,200 thread count sheets. Located blocks from the most important intersection in Harlingen, Ed Carey and Sunshine Strip. Major restaurants/shops nearby,and the hospital district and UTRGV, 2 blocks away. It will be your favorite home away from home in Harlingen!

Top guest favorite
A spacious master bedroom is furnished with a king-size bed, adorned with neutral linens. Two bedside lamps illuminate the space, and a large ceiling fan provides airflow. A desk and chair are positioned against one wall, with a view into the connected kitchen area.
Guest suite in Los Fresnos
5 out of 5 average rating, 406 reviews

Peaceful/Private Apartment with separate entrance

A peaceful haven and home away from home- that's how many have described this one bedroom, one bath apartment (700 sq ft), with fully-furnished kitchen, private patio and separate entrance . We tried to incorporate everything a person would need to be comfortable. We look forward to welcoming you to the Los Fresnos/South Padre Island/Brownsville area! This apartment is connected to our home and hosts live on premises, but it has its own private entrance.

Top guest favorite
A welcoming living room features a blue sofa with decorative pillows, flanked by two wooden side tables holding lamps. A neutral-colored area rug lies beneath a wooden coffee table, surrounded by a plush armchair and two textured poufs, while soft light fills the spacious area.
Guesthouse in Harlingen
4.99 out of 5 average rating, 109 reviews

Peaceful Country Getaway

This private, cozy guest house is next to our home and includes a bedroom, bathroom, full kitchen, and living room. It has a beautiful view of our 2.4 acre property. Amenities include a queen size bed, WiFi, refrigerator, oven, microwave, coffee maker and much more. Valley Baptist Medical Center–12 minutes Valley International Airport-15 minutes Brownsville–30 minutes McAllen–35 minutes South Padre Island–50 minutes

Guest favorite
Home in Mercedes
4.9 out of 5 average rating, 169 reviews

The house on mockingbird lane with private pool

Private pool Newly remodeled and furnished ready to make your stay as comfortable and convenient as possible! right off the expressway across from the outlet mall 3 minute drive) , 20 minutes away from McAllen, and 40 minutes away from South Padre Island! 5 minutes away from stock show grounds. Home sits on 1/2 acre in a quiet and peaceful neighborhood! 2 queen beds 2 twin beds Fold out sofa

Guest favorite
A spacious living area features a dark leather sectional sofa, paired with a sleek black recliner. Natural light fills the room through three windows, while a central coffee table stands between the seating. Decorative plants and modern light fixtures add a contemporary touch.
Apartment in Weslaco
4.92 out of 5 average rating, 139 reviews

Modern comfortable retreat in gated community!

Minutes away from the outlet mall, the Progreso International bridge & much more. Perfectly located in the mid valley so you can decide if you want a beach day or a shopping day!! We welcome long term guests, medical visits, corporate visits etc. We want you to feel as comfortable as possible while you stay with us! Enjoy the best AirBNB experience available!

Guest favorite
A dining area features a polished table set for four, complete with white dishware and glasses. Soft lighting is provided by a stylish chandelier overhead. A cozy living space is visible in the background, furnished with a couch and decorative accents, creating a harmonious atmosphere.
Apartment in Harlingen
4.93 out of 5 average rating, 107 reviews

Fresh, Modern + Convenient Apartment

Indulge in the serenity of this exceptional apartment nestled in Harlingen, one of the Rio Grande Valley’s burgeoning locales. Whether you’re seeking a relaxing vacation close to numerous amenities or traveling for business with convenience in mind, this impeccably clean home offers the perfect retreat for any purpose.

Guest favorite
Apartment in Weslaco
5 out of 5 average rating, 10 reviews

Executive Suite

Enjoy your private suite designed for comfort and productivity. Enjoy two full bathrooms, a private office for remote work, and a stylish open living space ideal for short or extended stays. Perfect for professionals seeking peace, privacy, and convenience. It's a four-minute drive to the expressway.

Top guest favorite
A living area features a large gray sofa and a two-seater couch, positioned across from a black entertainment unit with a television. Bright overhead lights illuminate the polished tile floor, while a dining area is visible in the background.
Home in Mercedes
4.95 out of 5 average rating, 79 reviews

Mid Valley Haven

Stay at a location close to everything in the Rio Grande Valley of Texas. The Premium Outlet Mall, the Rio Grande Live Stock Show Grounds, a border crossing to Mexico are all just minutes away. Centrally located to two hospitals (Knapp Medical Center and Valley Baptist Hospital).

Superhost
A well-organized kitchen displays light green cabinetry and a white stove. A wooden island with two stools serves as a central workspace. Natural light filters through the window, highlighting decorative elements, including a vase with flowers on the island.
Home in Weslaco
4.8 out of 5 average rating, 76 reviews

Citrus House

Your family will be close to everything when you stay at this centrally-located place. Everything is a short walking or driving distance. The citrus house was named after the beautiful citrus tree in the back yard. This house also has 3 pecan trees for all to enjoy.

Popular amenities for Santa Maria vacation rentals

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  2. United States
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  4. Cameron County
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