Vacation rentals in Santa Fe

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Top-rated vacation rentals in Santa Fe

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
Guesthouse in Manvel
4.94 out of 5 average rating, 290 reviews

Quiet, Cozy Guesthouse with privacy

Whether you are traveling alone, as a couple or even as a family our peaceful guest house is ready for your stay. The house, located in the backyard of our main residence, is approx 600 sqft with a bedroom, living room and a full kitchen with a small fridge. The area is fully fenced in for privacy along with a patio and furniture. We are less than 10 minutes from SH 288, 45 min from the beaches, 30 min from Texas Medical Center, 15 min from Pearland Town Center, 20 min from SkyDive Spaceland.

Top guest favorite
Guesthouse in Alvin
4.97 out of 5 average rating, 213 reviews

Holiday Comfort of Home Studio WiFi W/D Full Equip

Private, serene & clean guesthouse w/everything you need in a spacious, uncluttered 700 sq ft. • Cleaned by your SuperHost • Fast Wi‑Fi (532 Mbps) • In‑unit washer/dryer • Workspace • Full kitchen w/essentials • Excellent AC/Heat • Cozy couch & recliner • 55" Smart TV with Hulu & Disney+ included • Private bathroom & shower stocked with essentials • Outdoor lighted gardens w/ soothing water features Completely Detached from Main House Modern recessed LED lighting Midway Houston/Galveston

Guest favorite
A wooden bench is positioned on a grassy area adjacent to a calm river. Lush greenery and trees line the opposite bank, reflecting the warm colors of the foliage in the water. The scene conveys a serene, natural setting ideal for relaxation.
Guest suite in Dickinson
4.8 out of 5 average rating, 128 reviews

Riverside getaway between Houston & Galveston

Riverside Manor is a peaceful retreat outside of Houston, just 15 min from NASA and Galveston island. This self enclosed Guest suite has a private entrance, bathroom and kitchenette (no full stove). Exit through the kitchenette straight down to the river, where you can relax around the fire pit, fish in the Bayou or paddle a kayak (or 3). Property is raised up amongst the trees, surrounded by nature and peace. Can sleep 4 but best suited for one couple, families or 3 close friends.

Guest favorite
A cottage exterior is shown, featuring a sloped roof and several large windows. Steps lead up to the front door, surrounded by green grass and trees providing shade. The structure is set on a raised foundation, enhancing its charming appearance.
Cottage in Bacliff
4.94 out of 5 average rating, 260 reviews

Grandma’s getaway cottage.

Take it easy at this unique and tranquil getaway. This was truly a bay getaway before digital games and internet. There are two bookcases with hard bound books, card tables, and reading lamps. There is TV with WIFI and internet, a ductless HVAC system and a large 100'x 125' lot This cottage is very suitable for work away from home environment. A separate table and 2 office chairs are available for a work area that can be closed off from the rest of the house during the day.

Guest favorite
A modern living room is featured with a dark sofa and a coffee table. A television is positioned on a black entertainment unit, while a dining area with high chairs can be seen in the background. The space is highlighted by light wooden flooring and soft neutral wall colors.
Apartment in Alvin
4.97 out of 5 average rating, 147 reviews

Relax and clean apartment in Alvin Texas

We are committed following AB&B cleaning protocol and CDC recommendations. We are hosting for a minimum of 3 nights. 2 bedroom, 1 bath apartment in Downtown Alvin Texas. 1 queen bed, 2 twin beds (+under bed) and a sofa bed. Washer and drier in the apartment. Full kitchen and living room. Cable and high speed internet. Plenty of space to park in front of apartment. The property surrounded by tall trees in a quiet street. Please read reviews, you will not be disappointed.

Guest favorite
The front porch is framed by green grass and decorative shrubs. A seating area with comfortable chairs is positioned under the covered section. A wooden swing set is visible in the yard, contributing to the family-friendly environment.
Home in Dickinson
4.9 out of 5 average rating, 136 reviews

Cheerful 3 bedroom home with loft

Make some memories at this unique and family-friendly place. 2 bedrooms and 2 bathrooms downstairs with a loft upstairs hosting two beds. Great for multiple families, or families with children. This updated home is cozy and bright. Great for business professionals or friends and family trying to get away. Just minutes from NASA Johnson Space Center, Clear Lake, one of the biggest yachting communities in the USA, and Galveston Island. Your home away from home awaits!

Top guest favorite
A cozy living area is furnished with comfortable gray sofas and a glass coffee table. Soft gray curtains frame the window, providing a gentle backdrop. A flat-screen TV is positioned on a sleek stand, while a light ceiling fan circulates air overhead.
Home in Santa Fe
4.9 out of 5 average rating, 62 reviews

Comfortable 3 Bedroom Home with Garage

3 bedroom 2 bath home with large fenced back yard, 2 car attached garage, and driveway parking. Family friendly and pet friendly! Make this your home base for day trips to Moody Gardens in Galveston, Great Wolf Lodge and NASA Space Center in Clear Lake, the Boardwalk in Kemah, and the Houston Zoo and Museums. My home has all the necessary amenities for a comfortable stay: 4 comfortable beds, a well stocked kitchen, central AC, laundry, dishwasher, and disposal

Guest favorite
A recording studio is showcased with a wooden control desk equipped with multiple audio equipment and monitors. Neon lights illuminate the space with the name 'EPIK' prominently displayed. A keyboard and a sleek black couch are visible, creating a creative atmosphere.
Guest suite in League City
4.96 out of 5 average rating, 157 reviews

King Suite at Luxury Studio

Check-in starting 4p Early check-in options: 3p $10 2p $15 1p $20 12p $25 Check-out by 11a Late check-out options: 12p $10 1p $15 2p $20 3p $25 Please set your guest count for correct pricing. PRIVATE ENTRY Pictures 2-9 - bedroom w/ Cali King sized bed, 65” smart TV, bathroom w/ 2 vanities, soaking tub w/ jacuzzi jets, walk-in shower, large walk-in closet (doubles as small room w/ twin bed - ask), are all privately your area. Other pics show common area

Top guest favorite
A light-colored horse stands in a grassy area beside a winding creek, with a scenic barn and a white farmhouse visible in the background. Tall trees provide a natural border, enhancing the serene rural landscape.
Barn in Santa Fe
4.9 out of 5 average rating, 482 reviews

The Loft at Green Gables

Cozy barn apartment on a lovely small farm, secluded and quiet in the country. Located halfway between downtown Houston and the Galveston beaches, it's just a few minutes to lots of shopping and restaurants, with Kemah Boardwalk and Nasa Space Center a short drive away. Winding creek through the property, with chickens and two horses grazing in the pasture. Lots of sheep, pigs, and donkeys next door. Property has private swimming pool for your enjoyment.

Guest favorite
A three-story villa is displayed, featuring a modern exterior with white walls and a dark shingled roof. A landscaped yard with a stone border surrounds the entryway. A serene bayou lies adjacent to the property, with a private dock visible along the water's edge.
Villa in Dickinson
4.91 out of 5 average rating, 172 reviews

Waterfront Retreat Getaway Gameroom FirepitFishing

Enjoy a relaxing stay at the beautiful villa. It has a breathtaking view of the bayou. It is only 2 minutes away from I-45 highway, which is an easy commute to Nasa, Galveston, or Houston. As well as an outlet mall 5 minutes away. The house is equiped with a ton of amenties like fast wifi, a huge tv, a large backyard, a fire pit, a private dock, and even a kayak is provided. This unique place has a style all of its own.

Top guest favorite
A serene sunset illuminates the water, reflecting hues of orange and pink. Silhouettes of wooden piers extend into the calm bay, surrounded by tree branches that frame the scene, offering a peaceful view of the natural beauty.
Guest suite in San Leon
4.91 out of 5 average rating, 256 reviews

Me and the Sea-cozy waterfront apartment

Make some memories at this unique and family-friendly place. Near fantastic restaurants, Pier 6 and Top Water Grill. You'll never run out of fun in this cute apartment on the Bay. Great for boating, fishing, a romantic get-away, or just listening to the ocean waves. Want more to do? We are less than 10 miles from Kemah Boardwalk and 20 miles from Galveston Seawall.

Guest favorite
A two-story home is set among lush green grass and mature trees, creating a serene environment. The house features a classic design with large windows and a welcoming entryway. A clear pathway leads to the front door, enhancing accessibility.
Home in Dickinson
4.86 out of 5 average rating, 179 reviews

Beautiful Spacious 4 bedroom house.

Relax with the whole family at this peaceful place to stay. Come to enjoy this beautiful place. Great location for next day to Galveston cruise. Great for big family or family with children. The 4 bed- 2 bath home is in a convenient location and close to many area attractions including Kemah Boardwalk, NASA, and Restaurants, UTMB Hospital and more!!!

Popular amenities for Santa Fe vacation rentals

  1. Airbnb
  2. United States
  3. Texas
  4. Galveston County
  5. Santa Fe