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Apartment vacation rentals in Santa Fe

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santa Fe

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Guest favorite
Apartment in Miguel Hidalgo
4.84 out of 5 average rating, 125 reviews

Curated Apt w/Balcony | Prime District+Rooftop

Wake up in Polanco and enjoy one of Mexico City’s most sophisticated neighborhoods, steps from renowned restaurants, museums, and high-end boutiques. This apartment features contemporary design, a private balcony, and a curated atmosphere to unwind after exploring the city. The building offers a jacuzzi terrace, fully equipped gym, and a lounge with a pool table. Steps from Masaryk Avenue, Antara, and the Soumaya Museum. Ideal for urban getaways, couples, or flexible stays in a prime location.

Guest favorite
Apartment in Lomas de Sotelo
4.86 out of 5 average rating, 369 reviews

Bright & Modern Studio w/ Gym & Pool | VIATO HOMES

Our modern studio apartments by VIATO HOMES in Nomad Living are designed to maximize comfort and functionality in an open, contemporary layout. Each unit features a cozy sleeping area, full bathroom, compact fully equipped kitchen, and a stylish living space that’s perfect for business travelers, couples, or solo guests. Guests also enjoy access to building amenities including the gym, pool, coworking hub, and BBQ area, all within a secure building with 24/7 concierge and parking availability.

Top guest favorite
A modern dining area features a glass table with six chairs, accompanied by decorative vases and greenery. A comfortable living space is visible, highlighted by large windows offering city views and showcasing a lounge area with a sectional sofa and a wall-mounted TV.
Apartment in Cuajimalpa
4.96 out of 5 average rating, 107 reviews

Depa AvSantaFe yParqueLaMexicana

Disfruta de una gran experiencia sobre Av. Santa Fe, pegado al Parque la Mexicana y con acceso directo al parque (a un costado). El edificio está arriba del supermercado City Market, y cuenta con grandes amenidades. Disfruta del gimnasio muy bien equipado, billar, sala de juegos, terraza, sala de cine, ludoteca, rooftop con vistas panorámicas de toda la ciudad, etc. El depa está en piso 15, cuenta con 1 cajón de estacionamiento, cafetera super automática, aire acondicionado y calefacción.

Guest favorite
A sunlit corner features large floor-to-ceiling windows offering views of greenery outside. A dark wooden table is accompanied by two cushioned seats, while a cozy seating area with a collection of books and decorative items is situated nearby, contributing to a serene environment.
Apartment in Condesa
4.88 out of 5 average rating, 127 reviews

Kaya Kalpa-Organic Designer Apartment in Condesa

After a year-long remodeling project, I’m thrilled to present this personal residence Kaya Kalpa. Every inch of the property has been thoughtfully remodeled. Ideal place for artists, wanderers, all walks of life practitioners to come reset, reflect, and create.  The space is located on Amsterdam street in Condesa, one block from Parque Mexico. You’ll find all nice restaurants, cafes, and stores downstairs. Big supermarket, local Mercado, metro station…all within 5 minutes walking distance.

Top guest favorite
A spacious living area features a gray sofa and a minimalist chair on a textured rug. A coffee table sits in the center, surrounded by natural light from large, framed windows. A modern staircase leads to the upper level, complemented by a pendant light overhead.
Apartment in Roma Norte
4.9 out of 5 average rating, 338 reviews

Award-winning Loft in Roma´s Heart 24/7 Security

Design department. NEW and with an unbeatable location in Colonia Roma; Walk to the best restaurants, Galleries, and cafes but stay in a quiet area. Rosetta and Orinoco are just a stone's throw away, as are OMR Gallery and Luis Cabrera Park. There is simply no better location. Are you arriving early or leaving late? Don't worry, our doorman will store your bags at no cost. The apartment is impeccable and has all the services. The building has won several prestigious design prizes.

Superhost
A spacious living area features large glass windows allowing natural light to fill the space. Comfortable seating is arranged around a modern coffee table. A dining area with stylish chairs is visible, while lush greenery completes the inviting ambiance.
Apartment in Condesa
4.92 out of 5 average rating, 186 reviews

2BR/2BA Penthouse at Condesa. Air conditioning.

The main reasons for staying at this Penthouse are: Solar Panels 100% power generated (No gas). 24/7 security person at front door. Air Conditioning and heating at the bedrooms. Quiet (double glass window at street facing bedroom. No neighbours above you (you are top floor). No neighbors next to makes it super private. Elevator. Nice view and good sun orientation. Fully equipped to live like at home. Located in Condesa neighborhood (The best). Private Rooftop terrace.

Superhost
Apartment in Polanco
4.89 out of 5 average rating, 462 reviews

Kukun Homero Polanco

You’re about to discover your next stay! We’re thrilled to welcome you to our apartments. This building is not only in a prime location, but it also tells a story that celebrates contemporary Mexican art and culture. From handcrafted Talavera pieces made in Puebla to iconic quotes by renowned Mexican creatives like Octavio Paz and Alejandro González Iñárritu, every corner is designed to inspire you. Plus, you’ll get to enjoy one of the best views in the city.

Guest favorite
Apartment in Miguel Hidalgo
4.87 out of 5 average rating, 115 reviews

Premium Loft: A/C, KingSz Bed, Gym, Roof & Co-Work

Enjoy a premium experience in this central apartment with unique views, located in the heart of Mexico City and a few steps from Polanco. ✔ Air conditioning ✔ King Size Bed ✔ Rooftop ✔ Washer-dryer ✔ Business center ✔ Gym ✔ Children's playroom ✔ Designer furniture You will be located in the favorite colony by locals and travelers for its cultural offer and strategic location to move to all the most iconic sites in the city.

Top guest favorite
A spacious rooftop terrace features a Jacuzzi surrounded by lush greenery and modern outdoor furniture. A large glass enclosure offers panoramic views, while stylish pendant lights enhance the ambiance. A shaded area is created by a large umbrella, providing comfort for relaxation or social gatherings.
Apartment in Condesa
4.99 out of 5 average rating, 102 reviews

Epic Penthouse | Private Rooftop | Condesa

Welcome to our stunning penthouse (PH) in the heart of La Condesa, Mexico City's most vibrant and safe neighborhood. Recently remodeled, this luxurious property is just a stone's throw away from Parque España, surrounded by an array of museums, famed restaurants, chic cafes, art galleries, and lush parks, making it the perfect spot for travelers seeking a blend of cultural immersion and urban convenience.

Guest favorite
A modern living space features a black leather sofa facing a wall-mounted television. A glass table rests on a soft blue rug, with an elegant orchid arrangement placed centrally. Floor-to-ceiling windows allow natural light to illuminate the room, offering a view of the lively street outside.
Apartment in Polanco
4.95 out of 5 average rating, 154 reviews

Beautiful Apartment View Av Presidente Masaryk123

Enjoy Polanco and Mexico City in a modern apartment with an excellent location. Equipped with everything you need to feel at home. If you like history, culture, good food, enjoying the day and night, you'll be in the right place. In addition to the amenities included in the building: gym, jacuzzi, roof garden, parking. 24/7 security. Ideal for those who need something super central, clean, and safe,

Guest favorite
Apartment in Condesa
4.84 out of 5 average rating, 1,721 reviews

Chic & Equipped Apt | Rooftop+Gym+B/Center+Lounge

This stylish apartment in the heart Roma Norte and Condesa offers the perfect setup for digital nomads—ultra-fast Wi-Fi, a sleek workspace, and steps from the trendiest cafés, restaurants, and nightlife. Enjoy top-tier amenities: a business center, a full gym, a game room, and a rooftop with stunning views. Stay productive, stay inspired, and experience CDMX like a local.

Guest favorite
The living area features a bright and airy atmosphere with large windows allowing natural light. Comfortable seating is arranged around a low table on patterned black and white tiles. A dining table is also included, surrounded by chairs, enhancing the space's functionality.
Apartment in Roma Norte
4.9 out of 5 average rating, 436 reviews

Our beautiful quiet apartment, oasis in the City.

Departamento de 2 recamaras hasta para 4 personas ( recámara principal con cama queen size, recámara secundaria con 2 camas individuales); localizado al fondo de una calle cerrada, muy tranquilo; Tiene acceso a la azotea a través de la escalera de caracol. La velocidad del internet es de 40MB se puede escalar (con costo adicional) a 100, 250, 500 y 1000MB

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