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Apartment vacation rentals in Santa Fe

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santa Fe

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Top guest favorite
Apartment in Polanco

Luxury Polanco Stay | Best Location+Daily Service!

IN THE HEART OF POLANQUITO- steps from PARQUE LINCOLN & one block from Presidente Masaryk-this spacious 3BR retreat blends boutique-hotel comfort with local charm. Wake to tree-lined views; stroll to cafés, restaurants & museums incl. Anthropology Museum; return to relax in style. Enjoy rare perks: weekday housekeeping (Mon–Fri—beds made, dishes done), concierge connections, welcome basket, smart-lock entry, fast Wi-Fi & family amenities (crib & high chair on request). Laundry service included.

4.97 out of 5 average rating, 344 reviews
Guest favorite
A modern kitchen area is visible, featuring stainless steel appliances, including a refrigerator and stovetop. A dining table with four chairs is positioned nearby, adorned with dishes and a plant centerpiece. Neutral colors and tile flooring provide a clean and spacious ambiance.
Apartment in Álvaro Obregón

Jacarandas 100 - 2

Estrena hermoso departamento al sur de la ciudad de México, amueblado con todas las comodidades. A solo 5 minutos de Santa Fe o bien a 15 minutos de San Ángel. Cuenta con dos recamaras , principal con cama queen size , baño completo, amplio closet, pantalla. segunda con dos camas individuales o bien cama queen size , buró , amplio closet, baño completo. Cocina integral perfectamente equipada con todos los electrodoméstidos y accesorios. Área de lavado con lava secadora. Sala, comedor, Internet

4.88 out of 5 average rating, 107 reviews
Top guest favorite
A modern dining area features a glass table with six chairs, accompanied by decorative vases and greenery. A comfortable living space is visible, highlighted by large windows offering city views and showcasing a lounge area with a sectional sofa and a wall-mounted TV.
Apartment in Cuajimalpa

Depa AvSantaFe yParqueLaMexicana

Disfruta de una gran experiencia sobre Av. Santa Fe, pegado al Parque la Mexicana y con acceso directo al parque (a un costado). El edificio está arriba del supermercado City Market, y cuenta con grandes amenidades. Disfruta del gimnasio muy bien equipado, billar, sala de juegos, terraza, sala de cine, ludoteca, rooftop con vistas panorámicas de toda la ciudad, etc. El depa está en piso 15, cuenta con 1 cajón de estacionamiento, cafetera super automática, aire acondicionado y calefacción.

4.97 out of 5 average rating, 125 reviews
Guest favorite
A private terrace features two wicker chairs around a small table, providing a cozy seating area. Glass doors lead into the living space, accentuating the indoor-outdoor flow. Lush greenery is visible nearby, enhancing the tranquil setting.
Apartment in Condesa

New luxury apartment with View to Parque España

Enjoy this modern new apartment in the heart of Condesa, conveniently located in front of the beautiful Parque España, where you’ll find plenty of shops, restaurants, coffee shops, bars and more, all within walking distance. The two bedrooms are designed to provide tranquility and privacy. The kitchen is fully equipped, including a stove, oven and refrigerator. Help yourself to complimentary local bathroom products! This is the perfect spot if you enjoy lively, vibrant neighborhoods.

4.89 out of 5 average rating, 608 reviews
Guest favorite
Apartment in Álvaro Obregón

Depa cerca a Santa Fe, tranquilo y vista al bosque

Departamento muy iluminado, acogedor y cómodo, con una gran vista al bosque, ideal para relajarte y sentirte como en casa. Perfecto tanto para viajes de trabajo como para paseos en familia por la CDMX. A escasos 800 m se encuentra la estación de la linea 3 del Cablebús que conecta directamente con la parte más turística de la ciudad. Ubicado muy cerca del área comercial y de oficinas de Santa Fe. ¡Bienvenid@! Aquí encontrarás un espacio pensado para tu descanso y comodidad.

4.81 out of 5 average rating, 102 reviews
Top guest favorite
A cozy seating area is present, featuring a distinctive orange chair and a minimalist white table. Large glass doors offer an unobstructed view of lush greenery and palm trees outside, enhancing the bright and airy ambiance of the space.
Apartment in Condesa

Gran loft en la Condesa . La mejor ubicación

Increíble Loft en la mejor zona de la Condesa. Frente al parque España y a pasos del parque México. Un lugar estratégico en la Ciudad de México para pasear y comer delicioso. El depto es luminoso y muy acogedor. Tiene dos balcones, una cómoda sala y un comedor para 4, una barra con cocina abierta, una recámara con cama king y una gran TV para ver tus series y películas. La cocina es completa tiene todo lo que que necesitas .El atardecer es hermoso. Te encantará este lugar!

4.99 out of 5 average rating, 131 reviews
Guest favorite
A well-lit bedroom features a spacious bed with a textured white blanket, situated against a bold patterned accent wall. Large windows showcase views of the greenery outside and the city skyline. Two lamps provide soft lighting on either side of the bed.
Apartment in Condesa

Radiant Rooftop 2BR in Central Condesa w AC & Pool

You will be staying in one of the few Air Conditioned apartments that is perfectly located in Central Condesa. The flat is spacious and well lit with floor to ceiling windows and stylishly furnished. The Rooftop has a Heated Infinity Pool, a Lounge and Deck with majestic 360 views of Mexico City. The building has 24/7 Security personnel and a well equipped Gym. We pride ourselves in providing the best service for all our travelers and delivering you a wonderful experience.

4.88 out of 5 average rating, 134 reviews
Top guest favorite
Apartment in Polanco

Elegante Apartamento con Bella Vista a Masaryk

Un departamento espectacular. Un lugar lleno de amenidades en el corazón de Polanco la zona más exclusiva de la Ciudad de México. Limpieza diaria del departamento. Equipado con todo lo necesario para que te sientas como en casa. Cocina Equipada, refrigerador, horno de microondas, plancha, secadora de pelo, SmartTV, WIFI, Aire Acondicionado, lavadora y secadora al interior del departamento. Conserje y Vigilancia 24/7.

4.94 out of 5 average rating, 109 reviews
Luxe
A well-appointed bedroom features a spacious bed with crisp linens and soft pillows. Natural light floods the room through large windows, complemented by sheer curtains. A minimalist bedside table holds a soft-glowing lamp. A ceiling fan enhances comfort, and a contemporary design adds elegance.
Apartment in Roma Sur

Amazing apartment in Roma

Experience luxury living in the heart of Roma Sur, Mexico City. This incredible apartment offers elegance and sophistication. Step into a spacious, tastefully designed living space adorned with high-end finishes and stylish furnishings. Enjoy the building's exclusive amenities such as a , fitness center, working space, and 24/7 security. With its prime location, cultural hotspots, and trendy shops are just steps away.

4.92 out of 5 average rating, 116 reviews
Guest favorite
Large sculptures of hands are positioned outside a modern high-rise building. The hands, crafted from a textured material, stretch outward from dark poles, while a reflective glass facade and various greenery are visible in the background under a partly cloudy sky.
Apartment in Cuajimalpa

Ultra Modern Apartment at Santa Fe Mexico City

Luxury Apartment, one independent room - no loft - at Santa Fe Mexico City Come home to Peninsula Santa Fe, a stunning apartment bordering parks, business centers, and top shopping malls. Located in the heart of Santa Fe, this luxurious apartment also has a handful of exceptional features including sophisticated spaces, a fitness center, SPA, pool, top-of-the-line amenities and convenient transportation nearby.

4.88 out of 5 average rating, 254 reviews
Top guest favorite
A spacious rooftop terrace features a Jacuzzi surrounded by lush greenery and modern outdoor furniture. A large glass enclosure offers panoramic views, while stylish pendant lights enhance the ambiance. A shaded area is created by a large umbrella, providing comfort for relaxation or social gatherings.
Apartment in Condesa

Epic Penthouse | Private Rooftop | Condesa

Welcome to our stunning penthouse (PH) in the heart of La Condesa, Mexico City's most vibrant and safe neighborhood. Recently remodeled, this luxurious property is just a stone's throw away from Parque España, surrounded by an array of museums, famed restaurants, chic cafes, art galleries, and lush parks, making it the perfect spot for travelers seeking a blend of cultural immersion and urban convenience.

4.99 out of 5 average rating, 114 reviews
Guest favorite
A spacious living room features a large sectional sofa adorned with a warm throw. A sleek wooden coffee table sits in front, and a wall-mounted television is showcased on a stylish panel. Natural light streams through sliding glass doors, revealing views of the greenery outside.
Apartment in Polanco

Capitalia | Serene Polanco 2BR · Breakfast & Gym

Executive 2-bedroom apartment in Polanco's leafy Obelisk building, steps from Parque Lincoln and moments from Paseo de la Reforma. Breakfast is included, plus fast WiFi and a dedicated workspace — ideal for business travel and remote work. The building offers a gym, jacuzzi, elevator, private parking and 24/7 controlled access. Professionally managed by Capitalia — where a hotel meets home.

4.87 out of 5 average rating, 103 reviews

Popular amenities for Santa Fe apartment rentals

KitchenWifiPoolFree parking on premisesAir conditioning

Weekly apartment rentals

Guest favorite
A modern building is highlighted against a sunset backdrop, showcasing large glass windows that reveal the interior arrangement. The view extends over lush greenery and city skyscrapers in the distance, illustrating the connection between urban living and nature.
Apartment in Roma Norte

Exquisite Heaven: Condesa PH w/Rooftop Gym

4.86 out of 5 average rating, 132 reviews
Top guest favorite
The rooftop terrace features a comfortable seating area with a gray sofa and a round wooden table. A dining set with chairs is shaded by a large umbrella, while potted plants and tall cacti enhance the outdoor space. A charcoal grill is also present.
Apartment in Del Valle Centro

Casa KM | 4BR Penthouse with Private Rooftop

4.99 out of 5 average rating, 136 reviews
Top guest favorite
A comfortable living space features a dark sofa paired with a woven armchair. A coffee table is centered on a patterned rug. Large windows offer views of the lush garden, while a potted plant adds a touch of greenery to the room.
Apartment in Condesa

Beautiful garden house in the best part of Condesa

5.0 out of 5 average rating, 109 reviews
Guest favorite
A modern living space features a comfortable gray sectional sofa adorned with striped cushions. A round wooden table is prominently placed, accompanied by plush chairs. Large glass doors provide views of lush greenery, enhancing the room's bright and open ambiance.
Apartment in Narvarte Poniente

GM- New, cozy and beautiful apartment 2BR| 2BA

4.9 out of 5 average rating, 176 reviews
Guest favorite
A sunlit corner features large floor-to-ceiling windows offering views of greenery outside. A dark wooden table is accompanied by two cushioned seats, while a cozy seating area with a collection of books and decorative items is situated nearby, contributing to a serene environment.
Apartment in Condesa

Kaya Kalpa-Organic Designer Apartment in Condesa

4.89 out of 5 average rating, 135 reviews
Guest favorite
A spacious living area features large windows allowing natural light to flood the room. Modern furniture, including two stylish chairs and a comfortable sofa, is arranged around a glass coffee table. A dining table is set in the background, complemented by a vibrant wall art piece.
Apartment in Condesa

Magnificent 115m² Penthouse w/Terrace Elite Design

4.92 out of 5 average rating, 100 reviews
Superhost
Apartment in Santa Fe

Loft vista panorámica en la mejor zona de Santa Fe

5.0 out of 5 average rating, 3 reviews
Top guest favorite
A modern sleeping area features a spacious bed with a navy comforter and multiple pillows. A sleek, gray sofa bed adds seating flexibility. Decorative lighting fixtures are mounted on a textured wall, enhancing the contemporary aesthetic of the room.
Apartment in Cuajimalpa

Loft en Santa Fe

4.97 out of 5 average rating, 39 reviews

Private apartment rentals

Guest favorite
A spacious living area features light wood flooring and large windows allowing natural light to fill the room. Soft white sofas and colorful cushions are arranged around a central coffee table. A gently swaying hammock is visible, along with decorative art pieces adorning the walls.
Apartment in Santa Fe

Gorgeous apartment in the heart of Santa Fe

4.83 out of 5 average rating, 82 reviews
Guest favorite
Apartment in Polanco

Penthouse c/Jacuzzi Privado • Palacio Polanco

5.0 out of 5 average rating, 14 reviews
Guest favorite
Apartment in Álvaro Obregón

Apartment in Mexico City

5.0 out of 5 average rating, 17 reviews
Guest favorite
Apartment in Álvaro Obregón

Moderno Depto. cerca de Santa Fe + gym + vista SF

4.91 out of 5 average rating, 33 reviews
Top guest favorite
Apartment in Del Valle Centro

Suite de Lujo frente al WTC | Rooftop - Alberca

5.0 out of 5 average rating, 23 reviews
Superhost
A spacious living area features two dark sofas positioned around a glass coffee table atop a decorative area rug. Wall-mounted artwork is displayed, and the room is illuminated by ambient lighting, creating a comfortable and inviting space.
Apartment in Miguel Hidalgo

Santa Fe, espectacular alojamiento con balcón

4.87 out of 5 average rating, 47 reviews
Superhost
A sleeping area features a neatly made bed with a textured gray coverlet, complemented by a small table lamp. A stuffed animal rests on the bed, and a potted plant adds a touch of greenery near the edge of the image.
Apartment in Cuajimalpa

Hermoso LOFT en Santa Fe cdmx

4.91 out of 5 average rating, 74 reviews
Guest favorite
Apartment in Cuajimalpa

Luxury Bauhaus Nest (Pool/Gym/Park/Restaurant)

4.96 out of 5 average rating, 25 reviews

Apartment rentals with a hot tub

Guest favorite
Apartment in Miguel Hidalgo

Curated Apt w/Balcony | Prime District+Rooftop

4.86 out of 5 average rating, 143 reviews
Superhost
A bright and open kitchen area is displayed, featuring a sleek island with a stove. Large windows provide expansive views of the city skyline, allowing natural light to fill the space. A dining table is positioned nearby, enhancing the airy atmosphere.
Apartment in Condesa

360° Luxurious City view

4.84 out of 5 average rating, 161 reviews
Guest favorite
A dining area contains a wooden table with two bowls and a basket of fruit. Two wicker chairs are positioned on a balcony, which overlooks a cityscape. Sliding glass doors allow natural light to fill the space, enhancing the connection to the outdoors.
Apartment in Del Valle Centro

Jacuzzi para momentos especiales con AC

4.82 out of 5 average rating, 138 reviews
Top guest favorite
Apartment in Polanco

Antara Polanco | King, Balcony & Workspace

4.89 out of 5 average rating, 271 reviews
Guest favorite
Apartment in Condesa

Boutique Stay Steps from Parque España in Condesa

4.94 out of 5 average rating, 182 reviews
Guest favorite
A modern living space is highlighted by large windows that offer expansive views of Mexico City. A sleek kitchen area features white marble countertops and a gas stove. A cozy brown sofa is placed on a patterned area rug, complemented by a small round coffee table and decorative elements.
Apartment in Condesa

Stunning luxury apt breathtaking 360º city view

4.92 out of 5 average rating, 185 reviews
Superhost
An open living space features a comfortable sofa facing a modern kitchen area, equipped with stainless steel appliances. A wooden coffee table sits in front of the sofa, while a decorative shelf with plants separates the living area from the sleeping quarters, creating a stylish layout.
Apartment in Del Valle Centro

Nápoles NYC vibes | Roof, Alberca & Spa

4.82 out of 5 average rating, 153 reviews
Guest favorite
Apartment in Miguel Hidalgo

Sky view, gym, jacuzzi, parking, kitchen.

4.94 out of 5 average rating, 159 reviews