
Vacation rentals in Santa Fe District
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Top-rated vacation rentals in Santa Fe District
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Other great vacation rentals in Santa Fe District
Superhost

Hotel room in Santa Fe
4.91 out of 5 average rating, 11 reviewsDeluxe Quadruple Room
EvelynRating, 5 stars1 month ago
Nos encantó quedarnos aquí. La comida deliciosa, el staff super amigable y amable, siempre dispuestos a ayudar. La vista es increíble, el clima delicioso. Excelente lugar para relajarse y desconectarse. Amamos todo❤️
Superhost

Home in Santa Fe
5 out of 5 average rating, 4 reviewsErica’s Song
AlexandraRating, 5 starstoday
This place is absolutely magical. Just breathtakingly beautiful. We didn’t want to leave. A nice full kitchen, quiet and peaceful, beautiful grounds and pool, plus a very comfortable king size bed. Juana was extremely helpful when we arrived, greeted us warmly and gave us a tour of the grounds and showed us our house. Thank you for everything.
Superhost

Hotel room in Santa Fe
5 out of 5 average rating, 6 reviewsDeluxe Family Room
VladRating, 5 stars1 month ago
It's a bed and breakfast. Rooms are spacious and clean (there is no kitchen, or TV). Very peaceful, fantastic views. Great place to chill and disconnect from the world. There are numerous waterfalls and rivers within a 20 minute drive. If you are into bird watching, there are guides available. Sineth gave us a detailed binder with tours details. Basic breakfast is included. During dinner hours, Sineth offered a short menu of Asian style dishes, which we thoroughly enjoyed. Word of caution: there were chitras (aka noseems, aka sand flies) during dusk hours. Bring eucalyptus oil to apply to open skin (or ask in reception, they have it in stock). This is fairly common in Panama.
Guest favorite

Cabin in Santa Fe
4.82 out of 5 average rating, 38 reviewsCabane vue sur la riviere
LilyRating, 5 stars2 weeks ago
Durante las 9 noches que pasamos en el lugar, nos sentimos como en casa, se nota que está hecho con el corazón. Lugar fresco, tranquilo, perfecto para escaparse del estrés, descansar y conectar con la naturaleza. Elise siempre estuvo pendiente incluso antes de nuestra llegada y siempre respondió a nuestras dudas. Un lugar que son duda alguna regresaríamos.

Cabin in Santa Fe
4.7 out of 5 average rating, 46 reviewsCabane dans les arbres
YvonneRating, 5 stars1 week ago
Elise war sehr freundlich, sie hat uns alles erklärt. Sie Unterkunft war sehr schön, besonders der Blick auf das Wasser 😍☀️.. es gibt zwei Hunde, die sind etwas schüchtern, aber sind sehr friedlich;) Pura Vita
Superhost

Hotel room in Santa Fe
4.83 out of 5 average rating, 6 reviewsDeluxe Double Room
AdrianRating, 5 stars49 months ago
Karen and her family run this little hotel in a sweet and caring way. The location is just great, unbeatable. We are in love with the view and little garden. We felt in heaven. Location is unique and worth the bumpy ride. We will come back!
Guest favorite

Home in Santa Fe
4.92 out of 5 average rating, 26 reviewsSanta Fe House with an amazing view
JorgeRating, 5 stars2 weeks ago
We had a very nice stay in Santa Fe! The house was comfortable, well-equipped, and had everything we needed for a relaxing visit. Nestled in nature, it offers an incredible view—you can even see and hear the river from the house. One of the highlights was the direct access to the river, where we spent a full day swimming and unwinding in the peaceful surroundings. Keep in mind that being in nature also means sharing space with a few lizards, ants, and bugs—but that’s all part of the experience. Santa Fe itself is a lovely little town, full of charm and surrounded by stunning natural beauty. There are plenty of nature walks, waterfalls, and adventures to enjoy nearby. Communication was smooth throughout, and even though we arrived a bit late, accessing the house was easy and straightforward. Overall, a great stay!
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