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Vacation rentals in Santa Fe District

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Popular amenities for Santa Fe District vacation rentals

Other great vacation rentals in Santa Fe District

Superhost
A spacious room is configured with a Queen bed and two single beds, complemented by a sitting area featuring a couch. Natural light filters through a window, highlighting the subtle décor and warm tones of the interior. A cozy atmosphere is created with a coffee table set for refreshments.
Hotel room in Santa Fe
4.91 out of 5 average rating, 11 reviews

Deluxe Quadruple Room

EvelynRating, 5 stars1 month ago
We loved staying here. Delicious food, super friendly and kind staff, always willing to help. The view is amazing, the weather is delightful. A great place to relax and disconnect. We loved everything❤️
Superhost
A covered porch area is visible with a black wooden chair featuring colorful cushions. Lush greenery and palm trees create a natural backdrop, while distant mountains can be seen under a cloudy sky. Vibrant plants frame the scene, enhancing the tranquil outdoor setting.
Home in Santa Fe
5 out of 5 average rating, 4 reviews

Erica’s Song

AlexandraRating, 5 starstoday
This place is absolutely magical. Just breathtakingly beautiful. We didn’t want to leave. A nice full kitchen, quiet and peaceful, beautiful grounds and pool, plus a very comfortable king size bed. Juana was extremely helpful when we arrived, greeted us warmly and gave us a tour of the grounds and showed us our house. Thank you for everything.
Superhost
A spacious family room is displayed, featuring a queen bed and a set of bunk beds. A cozy sitting area includes a couch and a glass coffee table. Natural light enters through a window, revealing a simple decor of warm tones and minimalist furnishings.
Hotel room in Santa Fe
5 out of 5 average rating, 6 reviews

Deluxe Family Room

VladRating, 5 stars1 month ago
It's a bed and breakfast. Rooms are spacious and clean (there is no kitchen, or TV). Very peaceful, fantastic views. Great place to chill and disconnect from the world. There are numerous waterfalls and rivers within a 20 minute drive. If you are into bird watching, there are guides available. Sineth gave us a detailed binder with tours details. Basic breakfast is included. During dinner hours, Sineth offered a short menu of Asian style dishes, which we thoroughly enjoyed. Word of caution: there were chitras (aka noseems, aka sand flies) during dusk hours. Bring eucalyptus oil to apply to open skin (or ask in reception, they have it in stock). This is fairly common in Panama.
Guest favorite
A serene seating area is surrounded by natural woven walls, offering an unobstructed view of the tranquil river. Soft cushions are arranged on a wooden bench, while a glass table reflects the surrounding greenery. String lights provide gentle illumination, enhancing the peaceful atmosphere.
Cabin in Santa Fe
4.82 out of 5 average rating, 38 reviews

Cabin with river view

MarcinRating, 5 stars6 days ago
Great place by the river near Santa Fe, perfect for nature lovers. The cabin is open so you can hear the sound of the river and feel the wind.
A shaded outdoor seating area features white armchairs positioned around a glass coffee table. Lush greenery surrounds the space, providing a serene view of the Santa Maria River. The natural wood structure enhances the connection to the outdoors.
Cabin in Santa Fe
4.7 out of 5 average rating, 46 reviews

Treehouse

YvonneRating, 5 stars1 week ago
Elise was very friendly, she explained everything to us. She place was very nice, especially the view of the water😍☀️.. there are two dogs who are a little shy but are very peaceful;) Pura Vita
Superhost
A spacious room is presented with a Queen bed, complemented by decorative orange cushions. A sitting area features a wooden chair and a circular mirror. A window offers views of greenery outside, while light fixtures enhance the room's illumination.
Hotel room in Santa Fe
4.83 out of 5 average rating, 6 reviews

Deluxe Double Room

AdrianRating, 5 stars49 months ago
Karen and her family run this little hotel in a sweet and caring way. The location is just great, unbeatable. We are in love with the view and little garden. We felt in heaven. Location is unique and worth the bumpy ride. We will come back!
Guest favorite
The spacious patio features large wooden beams and expansive glass doors, providing a connection to the surrounding landscape. The tiles are arranged neatly, and blooming tropical plants add a touch of color, inviting guests to enjoy the views of the lush environment.
Home in Santa Fe
4.92 out of 5 average rating, 26 reviews

Santa Fe House with an amazing view

JorgeRating, 5 stars2 weeks ago
We had a very nice stay in Santa Fe! The house was comfortable, well-equipped, and had everything we needed for a relaxing visit. Nestled in nature, it offers an incredible view—you can even see and hear the river from the house. One of the highlights was the direct access to the river, where we spent a full day swimming and unwinding in the peaceful surroundings. Keep in mind that being in nature also means sharing space with a few lizards, ants, and bugs—but that’s all part of the experience. Santa Fe itself is a lovely little town, full of charm and surrounded by stunning natural beauty. There are plenty of nature walks, waterfalls, and adventures to enjoy nearby. Communication was smooth throughout, and even though we arrived a bit late, accessing the house was easy and straightforward. Overall, a great stay!