
Guesthouse vacation rentals near Saguaro National Park
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Top-rated guesthouse rentals near Saguaro National Park
Guests agree: these stays are highly rated for location, cleanliness, and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

RetroTrek Bungalow Private-Fenced-Cozy
Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

Serene Desert Casita - No Hidden fees Pets welcome
Escape to Cantering Coyote Casita: A private 800 sqft Guest House on 5 acres right outside the Saguaro National Park - East. Located outside the city; secluded and remote, yet close to city amenities. Perfect location for your desert adventure: hiking, bicycling, bird watching, or enjoying the serenity. You will have beautiful mountain views, fenced yard, covered parking, full kitchen, comfy King bed, private bathroom, washer/dryer, and keyless entry. Your well-behaved pets are welcome.

Little Hummingbird House -An Enchanted Food Forest
Casita Colibrí (Little Hummingbird House) - lush oasis flourishing with life nestled in The Enchanted Food Forest-home to fruit trees, gardens, koi pond, chickens, giant tortoise, dogs, cats, and its namesake, hummingbirds in Tucson's heart. Enjoy fresh eggs & fruit, wander garden paths, relax poolside, or watch koi beneath the waterfall. It's not just a place to stay—it’s a special place to slow down, reconnect, and breathe in beauty and life, where peace & magic are woven into every corner.

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Rooftop Casita in Civano Private Patio & Mtn Views
This clean and comfortable rooftop retreat is located in the heart of the Civano neighborhood steps from walking and bike paths, pools, tennis, parks and salons. Private entrance and parking space. 1B/1B with queen bed, kitchenette and living room with gel top sleeper sofa. This cozy casita includes a private 240 sq ft patio to enjoy sunsets & downstairs garden patio with fountain. Located near golf, Tucson's 131 mile bicycle loop, shopping, Saguaro Nat'l Park, Colossal Cave & Sabino Canyon.

Tranquil Bears Path Casita
This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.

Private Tucson Desert Guest House Getaway
This guest house is a pleasant desert retreat in Northeast Tucson, nestled on a large property with spectacular views of the Catalina Mountains. Minutes from from Sabino Canyon, Mt. Lemmon, and close to sumptuous dining. Guests will enjoy a recently space which includes a kitchenette complete with a microwave, coffee-maker, toaster oven, refrigerator, and more. Large bathroom and closet. Also available are a pool, BBQ grill, outdoor seating, and play yard. Laundry available upon request.

Cozy midtown guesthouse
A cozy, one-bedroom retreat on a peaceful bike boulevard. Features a queen bed, futon, and fully equipped kitchen. Minutes from the university via dedicated bike boulevards, close to city conveniences, ideal for work or relaxation. We offer a relaxed stay with minimal check-out tasks and transparent pricing. Amenities include a full kitchen, bathroom essentials, washer/dryer, WIFI, TV, AC/heat. Street parking available. Cleaned and disinfected regularly. Book your tranquil escape now!

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

Desert Getaway 2 Bedroom Guest House
Huge guest house located just 1/2 mile from Saguaro National Park East. This quiet getaway is nuzzled about 100 ft behind the main property on 3 acres and has it's own driveway and two parking spaces. It's perfect for an outdoor enthusiast with hiking and popular bicycling and mountain biking spots just minutes away. Fully functioning kitchen with washer/dryer, large walk in closets, outdoor dining set and BBQ. Everything you need for a peaceful extended stay in the desert!

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).
Popular amenities for guesthouse rentals near Saguaro National Park
Family-friendly guest house rentals

Knightly's Ranch Guesthouse

Sam Hughes oasis with pool, close to U of A

Upper Little Bird Hill

Charming Private Oasis Casita with Pool & Hot Tub

Pet Friendly Casita with striking Mountain View’s

The Cottage

Artistic Desert Guesthouse Retreat

Coyote Cavern: A Southwestern High Desert Retreat
Guest house rentals with a patio

Midtown-New Constr/Hot Tub/Full Kitchen/Private

The Coop- Luxury guest house with ideal location

Dunbar Springs Desert Oasis Guesthouse

Sunshine Loft

Southwest Solitude

Adobe Carriage House downtown Chiminea+Ramada

Midtown House near TMC & UofA•Fast WiFi •Self ChIn

*Prime Location: King Suite Guest House!*
Guest house rentals with a washer and dryer

Peaceful Desert Oasis in Central Tucson Foothills

Horse house

TREAT GUEST HOUSE Private, Quiet, Comfortable

The Outpost

Fun Retro Cottage

Central Casita Near Campus and Banner With Parking

Privacy, security, comfort, solar! Dog friendly!

Blue Lake Boutique Hotel
Other guesthouse vacation rentals

The Southwest Knest

Casa Rosa (Desert Oasis Casita w/ Mt Lemmon Views)

Private Casita in Casas Adobes

Copper House - Mid-century Modern Gem near U of A.

East Side Paradise Guest House with pool/mtn view!

Spanish Bungalow Casita with Private Patio

The Barn, Country living in Central Tucson!

Peaceful Desert Setting
Destinations to explore
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- Mount Lemmon
- Mt Lemmon Ski Valley
- University of Arizona
- Sabino Canyon
- University of Arizona
- Arizona-Sonora Desert Museum
- Tucson Convention Center
- Tumamoc Hill
- Patagonia Lake State Park
- Kartchner Caverns State Park
- Biosphere 2
- Sabino Canyon Recreation Area
- Titan Missile Museum
- Tucson Botanical Gardens
- Reid Park Zoo
- Catalina State Park
- Tucson Museum of Art
- Mission San Xavier del Bac
- Pima Air & Space Museum
- Rialto Theatre
- Tumacacori National Historical Park
- Sonoita Vineyards
- Children's Museum Tucson
- Trail Dust Town





