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Guesthouse vacation rentals near Saguaro National Park

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Top-rated guesthouse rentals near Saguaro National Park

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Tucson

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

4.96 out of 5 average rating, 526 reviews
Guest favorite
A dirt path lined with small stones leads to a rustic guesthouse, framed by a tall saguaro cactus and a leafy tree. Outdoor seating arrangements are visible, accompanied by potted plants resting near the entrance.
Guesthouse in Tucson

Knightly's Ranch Guesthouse

A beautiful, secure, private home on a fenced & gated private 5 acre property that sits adjacent to Saguaro National Park with horse & hiking paths galore. Access to trails, golfing, fishing, birding, photography, local biking and horseback riding. Desert landscape with abundant Tucson wildlife, it's secluded but easy access to anywhere in Tucson. Western setting & user-friendly site. A ranch on a dirt road with horses, dogs & chickens, bbq, stargazing & sunsets. The mountains & moon are yours!

4.85 out of 5 average rating, 278 reviews
Top guest favorite
A bright main room features a spacious bed dressed in a vibrant yellow and white blanket. Comfortable seating options, including a pair of light-toned sofas, are arranged around a wooden table. Natural light filters through partially covered windows, enhancing the welcoming atmosphere.
Guesthouse in Tucson

RetroTrek Bungalow Private-Fenced-Cozy

Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

4.98 out of 5 average rating, 340 reviews
Top guest favorite
A vibrant, sunlit patio area showcases colorful wall art on bright orange walls. A small table with two chairs sits beneath lush greenery, providing a perfect spot for outdoor dining. The space is adorned with various plants, enhancing the inviting atmosphere.
Guesthouse in Tucson

Little Hummingbird House -An Enchanted Food Forest

Casita Colibrí (Little Hummingbird House) - lush oasis flourishing with life nestled in The Enchanted Food Forest-home to fruit trees, gardens, koi pond, chickens, giant tortoise, dogs, cats, and its namesake, hummingbirds in Tucson's heart. Enjoy fresh eggs & fruit, wander garden paths, relax poolside, or watch koi beneath the waterfall. It's not just a place to stay—it’s a special place to slow down, reconnect, and breathe in beauty and life, where peace & magic are woven into every corner.

4.96 out of 5 average rating, 457 reviews
Top guest favorite
Guesthouse in Sam Hughes

Hues Casita - Airy Studio Near U of A

Located in Historic Sam Hughes, The Hues Casita provides a quiet retreat conveniently located walking distance from U of A and a 5 minute drive to downtown. Light-filled interior spaces provide simplistic comfort and convenience, great for traveling couples, students, or work travel. Experience the Sonoran Desert's incredible hiking, biking, and recreation opportunities nearby, as well as Tucson's famous "23 Miles of Mexican Food". Adjoins Desert Hues, which may be occupied during your stay.

4.96 out of 5 average rating, 135 reviews
Top guest favorite
A cozy living area is displayed with a brown sofa adorned with colorful throw pillows. A wooden coffee table sits in the center, surrounded by a woven decorative basket. Natural light filters through the large window framed by blue curtains, illuminating the warm hues of the walls.
Guesthouse in Tucson

Tranquil Bears Path Casita

This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.

4.98 out of 5 average rating, 375 reviews
Top guest favorite
A charming exterior view of the guest house is presented, featuring colorful potted plants arranged along the pathway. A cozy seating area with white chairs is visible beside the entrance adorned with a vibrant door, framed by warm lighting and lush greenery.
Guesthouse in Tucson

Private Tucson Desert Guest House Getaway

This guest house is a pleasant desert retreat in Northeast Tucson, nestled on a large property with spectacular views of the Catalina Mountains. Minutes from from Sabino Canyon, Mt. Lemmon, and close to sumptuous dining. Guests will enjoy a recently space which includes a kitchenette complete with a microwave, coffee-maker, toaster oven, refrigerator, and more. Large bathroom and closet. Also available are a pool, BBQ grill, outdoor seating, and play yard. Laundry available upon request.

4.97 out of 5 average rating, 893 reviews
Guest favorite
A rustic adobe exterior is adorned with a wooden door framed by natural wood accents. Prickly pear cacti grow on either side, set against a textured adobe wall. Pebbles cover the ground, complementing the earthy tones of the structure.
Guesthouse in Tucson

Adobe Carriage House downtown Chiminea+Ramada

This studio is spacious & comfortable. It is detached, secluded, on a quiet street, ample street parking and completely fenced in. The yard has a ramada with a table, chairs, string lights and a chiminea Inside, you’ll love the exposed adobe, skylight, and wood beam ceilings. The fully stocked kitchen is updated, with full size appliances. In the heart of Armory Park, it is close to 5-points, downtown, historic 4th Ave and Uof A. Ask me for dining, hiking, shopping and day trip recs!

4.94 out of 5 average rating, 182 reviews
Top guest favorite
A comfortable living area is presented, featuring a brown leather sofa opposite a circular wooden coffee table. A colorful area rug adds texture to the floor, while a floor lamp and a large mirror enhance the inviting ambiance. Bright yellow curtains frame a nearby window.
Guesthouse in Tucson

The Southwest Knest

Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!

4.97 out of 5 average rating, 532 reviews
Top guest favorite
The bright bedroom features a spacious bed with soft linens and two yellow accent pillows. Natural light fills the space through large windows, which overlook a serene outdoor area with cacti. Comfortable seating options, including armchairs and a round pouf, accompany the bed.
Guesthouse in Tucson

Central and Stylish Midcentury Pool House

Our beautiful adobe pool house is a Tucson gem. Comfortable queen bed, fireplace, and stylish modern furnishings with large windows looking out to trees and sparkling pool. Vaulted ceilings and natural light make for a restful space. Located in historic Jefferson Park, it’s a midtown oasis close to the UofA and two blocks from the UMC/Banner Medical Center. Midtown/University location allows for convenient access to all of Tucson. *Newly improved high speed WiFi 11/1/2021

4.95 out of 5 average rating, 570 reviews
Top guest favorite
A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.
Guesthouse in Tucson

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

4.96 out of 5 average rating, 924 reviews
Top guest favorite
A cozy sleeping area features a spacious bed topped with light-colored linens and decorative pillows. Warm tones are presented on the accent wall, while bedside lighting and a simple nightstand enhance the inviting space. Natural light filters in through a nearby window, contributing to a bright atmosphere.
Guesthouse in Tucson

Charming Desert Guesthouse

Welcome to the desert! You’ll enjoy views, views, and more views of a beautiful desert landscape. We are centrally located on the east side of Tucson, placing us 10-20 min from great restaurants, hiking trails, Saguaro National Park and the University of Arizona. Our charming guesthouse has everything you’ll need and is pet friendly. You’ll have a private getaway with parking on site and a spacious outdoor shower. We can’t wait to host you.

4.92 out of 5 average rating, 170 reviews

Popular amenities for guesthouse rentals near Saguaro National Park

KitchenWifiPoolFree parking on premisesAir conditioning

Family-friendly guest house rentals

Guest favorite
The exterior of a two-story guest house is featured, showcasing a serene pool surrounded by a stone patio. Lush greenery enhances the space, with a clear sky overhead. A balcony is visible from the second floor, overlooking the inviting pool area.
Guesthouse in Sam Hughes

Sam Hughes oasis with pool, close to U of A

4.92 out of 5 average rating, 245 reviews
Top guest favorite
A tranquil outdoor space features a stone fountain surrounded by potted plants and low shrubs. A small table with two chairs is set on a tiled patio. A blue staircase leads to the upper level, and colorful flowers add a vibrant touch to the scenery.
Guesthouse in Tucson

Rooftop Casita in Civano Private Patio & Mtn Views

5.0 out of 5 average rating, 175 reviews
Guest favorite
Guesthouse in Tucson

Coyote Cavern: A Southwestern High Desert Retreat

4.83 out of 5 average rating, 117 reviews
Top guest favorite
A separate guest house is situated amidst a lush green lawn, framed by desert vegetation. Earthy-toned walls harmonize with the surrounding landscape. A patio area is visible, adorned with potted plants, offering an inviting spot to relax outdoors.
Guesthouse in Tucson

Peaceful Desert Setting

4.98 out of 5 average rating, 131 reviews
Top guest favorite
A comfortable seating area is showcased with a gray futon, complemented by a wooden coffee table. A bright wall features a sun and cactus mural, while a framed art piece adds character. Bookshelves filled with various books provide an inviting touch.
Guesthouse in Tucson

Cozy midtown guesthouse

4.99 out of 5 average rating, 153 reviews
Top guest favorite
The entrance features a wooden door framed by a decorative overhang. Flanking the door are large windows that allow natural light, while surrounding vegetation adds a touch of greenery. Colorful tile accents are visible on the steps leading to the door.
Guesthouse in Tucson

Artistic Desert Guesthouse Retreat

4.96 out of 5 average rating, 231 reviews
Guest favorite
Guesthouse in Tucson

Serene Desert Casita - No Hidden fees Pets welcome

4.87 out of 5 average rating, 148 reviews
Superhost
Guesthouse in Tucson

Midtown House near TMC & UofA•Fast WiFi •Self ChIn

4.84 out of 5 average rating, 160 reviews

Guest house rentals with a patio

Top guest favorite
An outdoor patio area is shown, featuring a hot tub and a grill alongside a gravel-covered space. A dining table with chairs is arranged nearby, and a privacy fence encloses the area, while a colorful sky enhances the evening setting.
Guesthouse in Tucson

Midtown-New Constr/Hot Tub/Full Kitchen/Private

4.96 out of 5 average rating, 120 reviews
Guest favorite
A modern kitchen is showcased with wooden cabinetry and dark appliances. A spacious white countertop extends into a breakfast bar with two wooden stools. A door leading to the outside is visible, framed by natural light, creating an open and inviting atmosphere.
Guesthouse in Tucson

The Coop- Luxury guest house with ideal location

4.96 out of 5 average rating, 255 reviews
Top guest favorite
A cozy living area includes a white futon draped with decorative pillows and a rustic coffee table. A flat-screen TV is mounted on the wall, along with a framed artwork. A green cactus and accent chair provide natural and comfortable elements to the space.
Guesthouse in Tucson

Southwest Solitude

4.99 out of 5 average rating, 161 reviews
Superhost
A cozy studio space is highlighted with warm wood accents. A spacious bed features decorative pillows, while a kitchenette with a mini-fridge, microwave, and sink is visible in the background. Natural light enters through the window, illuminating the inviting interior.
Guesthouse in Tucson

Historic University area Downtown 4th Ave Studio!

4.77 out of 5 average rating, 252 reviews
Guest favorite
The exterior of the guest house is showcased, featuring crisp white walls and a modern blue roof. Large windows allow natural light to illuminate the entrance, which is bordered by minimalist plants in black pots. A concrete porch extends across the front.
Guesthouse in Tucson

Dunbar Springs Desert Oasis Guesthouse

4.89 out of 5 average rating, 295 reviews
Guest favorite
The two-story guesthouse features a Southwestern stucco exterior and large windows that invite natural light. A pool sits in the foreground, surrounded by a patio area furnished with outdoor seating and lush greenery. The outdoor space offers a quiet, relaxing atmosphere.
Guesthouse in Tucson

Sunshine Loft

4.9 out of 5 average rating, 257 reviews
Guest favorite
An open living area features comfortable seating arrangements with two recliners, a flat-screen television, and a dining table. A modern kitchen with stainless steel appliances and a stackable laundry unit is visible, complemented by natural light from overhead fixtures.
Guesthouse in Tucson

Gorgeous Guest House: private Yard lot of parking

4.92 out of 5 average rating, 144 reviews
Top guest favorite
A modern living space features a comfortable black sofa and a wooden coffee table with a simple decorative tray. A dining area with a white table and four chairs is visible, alongside a kitchen equipped with dark cabinetry and appliances. Natural light enters through large glass doors leading to an outdoor space.
Guesthouse in Tucson

Casita Chapulin

4.98 out of 5 average rating, 155 reviews

Guest house rentals with a washer and dryer

Top guest favorite
A cozy living area features vibrant orange sofas surrounding a central coffee table on wheels. Warm ambient lighting is provided by a hanging lamp and table lamps. Soft textures and earthy tones are complemented by natural light from a window, creating an inviting space for relaxation.
Guesthouse in Tucson

Fun Retro Cottage

4.98 out of 5 average rating, 165 reviews
Superhost
An outdoor seating area is positioned near the entrance, featuring two chairs and a small table. Surrounding greenery includes potted plants and cacti. A fabric canopy provides shade, while overhead lights create an inviting atmosphere. The rustic structure's metal and wood textures are prominently displayed.
Guesthouse in Tucson

Luxy House

4.9 out of 5 average rating, 227 reviews
Superhost
A light-colored entrance features a door with a semi-circular window. Two wooden chairs are positioned on the steps, accompanied by a small table. Natural elements, including a tree with string lights, frame the entrance, creating a welcoming outdoor space.
Guesthouse in Tucson

🌵 Central Desert Oasis 3 🌵

4.93 out of 5 average rating, 273 reviews
Top guest favorite
A modern kitchen space is visible, featuring grey cabinetry and a white countertop with a small seating area. A bar stool is placed next to a round table. Light from a window illuminates the area, with a TV mounted on the wall in the background.
Guesthouse in Tucson

Modern 1 bdrm Casita in Central Broadmoor Village

5.0 out of 5 average rating, 113 reviews
Top guest favorite
Guesthouse in Tucson

Central Casita Near Campus and Banner With Parking

4.97 out of 5 average rating, 242 reviews
Guest favorite
The exterior of a guest house is showcased, featuring a covered patio with seating and a textured stucco facade. Surrounding vegetation includes desert plants, under a clear blue sky. A gravel area is noted, providing a natural and unobtrusive landscape.
Guesthouse in Tucson

Desert Getaway 2 Bedroom Guest House

4.97 out of 5 average rating, 153 reviews
Top guest favorite
The saltwater pool features a clear, shimmering surface, surrounded by a spacious deck. Two lounge chairs with wooden frames are positioned nearby for relaxation, while potted plants add a touch of greenery along the perimeter.
Guesthouse in Sam Hughes

Blue Lake Boutique Hotel

4.95 out of 5 average rating, 229 reviews
Guest favorite
Guesthouse in Tucson

Casita de Jardin

4.9 out of 5 average rating, 105 reviews

Other guesthouse vacation rentals

Top guest favorite
The exterior of the guest house displays a charming design with a shaded seating area under a red canopy. A fenced entrance and a pathway lead to the private entry door, showcasing a gentle contrast between the earthy tones of the structure and the bright blue sky.
Guesthouse in Tucson

Guesthouse Studio in Barrio San Antonio

4.92 out of 5 average rating, 118 reviews
Guest favorite
Guesthouse in Tucson

Upper Little Bird Hill

4.85 out of 5 average rating, 126 reviews
Guest favorite
The spacious interior features a cozy sleeping area with a neatly made bed and a ceiling fan. Natural light enters through a large window, illuminating a seating area with a chair and small table. A dresser and artwork are also visible, contributing to the inviting atmosphere.
Guesthouse in Tucson

The Dog House

4.83 out of 5 average rating, 237 reviews
Guest favorite
A shaded outdoor space features a purple ramada supported by wooden beams. Comfortable seating is arranged around a central dining table. Colorful garden plants and decorations surround the area, contributing to a relaxed ambiance. A tiled surface adds a decorative touch to the setting.
Guesthouse in Tucson

Casa de Colores Tucson

4.92 out of 5 average rating, 160 reviews
Guest favorite
A detached casita presents a charming exterior with arched entryways and a subtle beige facade. The approach features a paved path with wheelchair-accessible handrails. Surrounding desert landscaping with small rocks and native plants contributes to the tranquil atmosphere of the foothills setting.
Guesthouse in Tucson

Peaceful Casita in the Foothills

4.96 out of 5 average rating, 776 reviews
Guest favorite
A spacious room features a queen bed with a light gray blanket, accompanied by two bedside lamps providing soft illumination. A small bench is placed at the foot of the bed. Dark curtains frame the window, while a modern fan enhances airflow. A cozy chair adds seating comfort.
Guesthouse in Tucson

Casita De Reflexión

4.86 out of 5 average rating, 242 reviews
Top guest favorite
A comfortable sleeping area features a spacious bed with white linens and two orange accent pillows. A ceiling fan provides ventilation. A desk with a chair is positioned beside the bed. Natural light enters through the window, adorned with light curtains, illuminating the warm wood flooring.
Guesthouse in Tucson

Studio Guesthouse

4.97 out of 5 average rating, 110 reviews
Top guest favorite
Guesthouse in Tucson

Modern Retreat in mid-town, close to everything

5.0 out of 5 average rating, 18 reviews

Destinations to explore