
Guesthouse vacation rentals near Saguaro National Park
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Top-rated guesthouse rentals near Saguaro National Park
Guests agree: these stays are highly rated for location, cleanliness, and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

RetroTrek Bungalow Private-Fenced-Cozy
Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

Little Hummingbird House -An Enchanted Food Forest
Casita Colibrí (Little Hummingbird House) - lush oasis flourishing with life nestled in The Enchanted Food Forest-home to fruit trees, gardens, koi pond, chickens, giant tortoise, dogs, cats, and its namesake, hummingbirds in Tucson's heart. Enjoy fresh eggs & fruit, wander garden paths, relax poolside, or watch koi beneath the waterfall. It's not just a place to stay—it’s a special place to slow down, reconnect, and breathe in beauty and life, where peace & magic are woven into every corner.

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Studio in the Saguaro Forest
New modern studio guesthouse on 3.2 lush acres secluded at the edge of the Saguaro National Park! Cleaning fees included in nightly rate. Private indoor/outdoor living areas. 8 miles easy access to downtown, 9 miles to the Desert Museum. High speed Starlink WiFi, Tuft & Needle queen bed, washer/dryer combo, 4k smart TV, whisper quiet mini split, full size sleeper sofa for 3rd guest. Nice retreat from midtown traffic. Check out my other similar listing on the property. LICENSE: 21465687

Tranquil Bears Path Casita
This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.

Southwest Solitude
Experience the best of Tucson. This welcoming retreat is designed with comfort in mind. Enjoy the unique blend of midcentury Tucson and Southwest flair. It is conveniently located on a quiet cul-de-sac near Tucson’s most beloved attractions. It features private off-street parking and entrance, an inviting patio, and a full kitchen to help you feel at home. Make your stay in Tucson truly unforgettable. Book now and start planning your perfect desert getaway at this peaceful retreat.

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

The Southwest Knest
Cozy and charming, this private guest house sits in the heart of Tucson and makes a perfect home base during your visit to the Southwest! Studio layout is spacious and relaxing for 2. Fully equipped kitchen, bathroom with walk-in shower, Ghostbed mattress, and comfortable work space/fast wifi for those of you working remotely. Easy access to airport, U of A, Saguaro NP, shopping, and hiking trails. Coded entry makes it a breeze to come and go, no shared keys. Come rest at the Knest!

Desert Getaway 2 Bedroom Guest House
Huge guest house located just 1/2 mile from Saguaro National Park East. This quiet getaway is nuzzled about 100 ft behind the main property on 3 acres and has it's own driveway and two parking spaces. It's perfect for an outdoor enthusiast with hiking and popular bicycling and mountain biking spots just minutes away. Fully functioning kitchen with washer/dryer, large walk in closets, outdoor dining set and BBQ. Everything you need for a peaceful extended stay in the desert!

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Time Capsule in the Sonoran Desert
Vibrant space-age cabin on an 11-acre desert art sanctuary near Saguaro National Park, 35 mins from Tucson! Features WiFi, AC/heat, outdoor bathroom deck & eco-amenities. Sits 15 yards from Groovy Glamper. 🚫 NO PETS/ESAs (Service Animals welcome). Delicate art decor makes this space strictly UNSUITABLE for children/minors. ⚠️ IMPORTANT: Before booking, note that check-in is strictly in person and no later than 10:00 PM. No exceptions!
Popular amenities for guesthouse rentals near Saguaro National Park
Family-friendly guest house rentals

Charming Desert Guesthouse

Charming Private Oasis Casita with Pool & Hot Tub

Private Tucson Desert Guest House Getaway

Pet Friendly Casita with striking Mountain View’s

Central Linden Beauty

Serene Desert Casita No cleaning fee, Pets welcome

Central and Stylish Midcentury Pool House

Rooftop Casita in Civano Private Patio & Mtn Views
Guest house rentals with a patio

Tucson Mountain Hillside House

The Coop- Luxury guest house with ideal location

Dunbar Springs Desert Oasis Guesthouse

Guest Cottage located near University and Downtown

Sunshine Loft

CasaJaguarTucson Blanca | near Saguaro Nat Park

*Prime Location: King Suite Guest House!*

Historic University area Downtown 4th Ave Studio!
Guest house rentals with a washer and dryer

Golden moments in Oro Valley/Tucson

Modern 1 bdrm Casita in Central Broadmoor Village

Extra-Spacious 1BR Guesthouse Close to UA

TREAT GUEST HOUSE Private, Quiet, Comfortable

The Outpost

Blue Lake Boutique Hotel

Peaceful, quiet getaway

Private Jackson Ave. Casita
Other guesthouse vacation rentals

Casa Rosa (Desert Oasis Casita w/ Mt Lemmon Views)

Spanish Bungalow Casita with Private Patio

Upper Little Bird Hill

Artistic Desert Guesthouse Retreat

Private Casita in Casas Adobes

Peaceful Desert Setting

East Side Paradise Guest House with pool/mtn view!

The Hummingbird, a very tranquil
Destinations to explore
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- Mount Lemmon
- Mt Lemmon Ski Valley
- University of Arizona
- Sabino Canyon
- University of Arizona
- Tumamoc Hill
- Kartchner Caverns State Park
- Arizona-Sonora Desert Museum
- Patagonia Lake State Park
- Biosphere 2
- Tucson Convention Center
- Sabino Canyon Recreation Area
- Tucson Botanical Gardens
- Titan Missile Museum
- Reid Park Zoo
- Catalina State Park
- Mission San Xavier del Bac
- Tucson Museum of Art
- Pima Air & Space Museum
- Rialto Theatre
- Tumacacori National Historical Park
- Sonoita Vineyards
- Children's Museum Tucson
- Mini Time Machine Museum of Miniatures





