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Guesthouse vacation rentals near Saguaro National Park

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Top-rated guesthouse rentals near Saguaro National Park

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Tucson

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

4.96 out of 5 average rating, 517 reviews
Guest favorite
A single-story brick guesthouse is surrounded by desert vegetation, including cacti and low shrubs. Large windows provide natural light, and outdoor seating is visible, inviting relaxation. A satellite dish is mounted on the roof under a clear blue sky.
Guesthouse in Tucson

Knightly's Ranch Guesthouse

A beautiful, secure, private home on a fenced & gated private 5 acre property that sits adjacent to Saguaro National Park with horse & hiking paths galore. Access to trails, golfing, fishing, birding, photography, local biking and horseback riding. Desert landscape with abundant Tucson wildlife, it's secluded but easy access to anywhere in Tucson. Western setting & user-friendly site. A ranch on a dirt road with horses, dogs & chickens, bbq, stargazing & sunsets. The mountains & moon are yours!

4.85 out of 5 average rating, 278 reviews
Top guest favorite
A bright main room features a spacious bed dressed in a vibrant yellow and white blanket. Comfortable seating options, including a pair of light-toned sofas, are arranged around a wooden table. Natural light filters through partially covered windows, enhancing the welcoming atmosphere.
Guesthouse in Tucson

RetroTrek Bungalow Private-Fenced-Cozy

Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

4.98 out of 5 average rating, 335 reviews
Top guest favorite
A vibrant, sunlit patio area showcases colorful wall art on bright orange walls. A small table with two chairs sits beneath lush greenery, providing a perfect spot for outdoor dining. The space is adorned with various plants, enhancing the inviting atmosphere.
Guesthouse in Tucson

Little Hummingbird House -An Enchanted Food Forest

Casita Colibrí (Little Hummingbird House) - lush oasis flourishing with life nestled in The Enchanted Food Forest-home to fruit trees, gardens, koi pond, chickens, giant tortoise, dogs, cats, and its namesake, hummingbirds in Tucson's heart. Enjoy fresh eggs & fruit, wander garden paths, relax poolside, or watch koi beneath the waterfall. It's not just a place to stay—it’s a special place to slow down, reconnect, and breathe in beauty and life, where peace & magic are woven into every corner.

4.96 out of 5 average rating, 456 reviews
Top guest favorite
The guesthouse is set against a backdrop of desert landscape, showcasing a simple, earthy exterior. A wooden porch with railings invites guests to enjoy the outdoor space. Desert vegetation, including cacti and shrubs, enhances the natural surroundings, along with rocky pathways leading to the house.
Guesthouse in Tucson

West-side Trailhead Retreat in the Sonoran Desert

2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

4.99 out of 5 average rating, 369 reviews
Top guest favorite
A modern studio guesthouse is set amidst a serene desert landscape, surrounded by various native cacti and shrubs. A mix of green and gray vegetation covers the ground, contrasting with the gravel driveway leading to the entrance. Majestic saguaro cacti tower nearby under a partly cloudy sky.
Guesthouse in Tucson

Studio in the Saguaro Forest

New modern studio guesthouse on 3.2 lush acres secluded at the edge of the Saguaro National Park! Cleaning fees included in nightly rate. Private indoor/outdoor living areas. 8 miles easy access to downtown, 9 miles to the Desert Museum. High speed Starlink WiFi, Tuft & Needle queen bed, washer/dryer combo, 4k smart TV, whisper quiet mini split, full size sleeper sofa for 3rd guest. Nice retreat from midtown traffic. Check out my other similar listing on the property. LICENSE: 21465687

4.99 out of 5 average rating, 473 reviews
Top guest favorite
A cozy living area is displayed with a brown sofa adorned with colorful throw pillows. A wooden coffee table sits in the center, surrounded by a woven decorative basket. Natural light filters through the large window framed by blue curtains, illuminating the warm hues of the walls.
Guesthouse in Tucson

Tranquil Bears Path Casita

This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.

4.98 out of 5 average rating, 375 reviews
Guest favorite
Guesthouse in Tucson

Serene Desert Casita No cleaning fee, Pets welcome

Escape to Cantering Coyote Casita: A quiet 800 sqft studio on 5 acres right outside the Saguaro National Park - East. Located outside the city; secluded and remote, yet close to city amenities. Perfect location for your desert adventure: hiking, bicycling, bird watching, or enjoying the serenity. You will have beautiful mountain views, fenced yard, covered parking, full kitchen, comfy King bed, private bathroom, washer/dryer, and keyless entry. Your well-behaved pets are welcome.

4.87 out of 5 average rating, 148 reviews
Top guest favorite
A comfortable seating area is showcased with a gray futon, complemented by a wooden coffee table. A bright wall features a sun and cactus mural, while a framed art piece adds character. Bookshelves filled with various books provide an inviting touch.
Guesthouse in Tucson

Cozy midtown guesthouse

A cozy, one-bedroom retreat on a peaceful bike boulevard. Features a queen bed, futon, and fully equipped kitchen. Minutes from the university via dedicated bike boulevards, close to city conveniences, ideal for work or relaxation. We offer a relaxed stay with minimal check-out tasks and transparent pricing. Amenities include a full kitchen, bathroom essentials, washer/dryer, WIFI, TV, AC/heat. Street parking available. Cleaned and disinfected regularly. Book your tranquil escape now!

4.99 out of 5 average rating, 150 reviews
Top guest favorite
A dining area is presented with a wooden table set for a meal, surrounded by woven chairs. Large arched windows provide views of the garden, allowing natural light to fill the space. Decorative plants and vibrant table settings add a touch of warmth.
Guesthouse in Tucson

Attractive Casita In Tucson

A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

5.0 out of 5 average rating, 126 reviews
Top guest favorite
A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.
Guesthouse in Tucson

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

4.96 out of 5 average rating, 918 reviews
Top guest favorite
The vibrant blue exterior of the guesthouse is softly illuminated by warm lights, highlighting the welcoming entrance. A textured stone path leads to the door, flanked by a cozy seating area with two chairs and a small table, set amid the serene outdoor landscape.
Guesthouse in Sam Hughes

TREAT GUEST HOUSE Private, Quiet, Comfortable

Himmel Park pool is very close by and open in June & July. Welcome to a one-of-a-kind guesthouse created by a Swiss-born professional photographer and freelance artist. This attractive open studio space is part of my "Gesamtkunstwerk" (entire body of work), still in flux. Featuring murals and curated pieces from across a lifelong creative journey. Thoughtfully designed with passion and purpose, the space offers both inspiration and comfort in the heart of Tucson.

4.99 out of 5 average rating, 677 reviews

Popular amenities for guesthouse rentals near Saguaro National Park

KitchenWifiPoolFree parking on premisesAir conditioning

Family-friendly guest house rentals

Guest favorite
Guesthouse in Tucson

Upper Little Bird Hill

4.85 out of 5 average rating, 126 reviews
Guest favorite
The exterior of a two-story guest house is featured, showcasing a serene pool surrounded by a stone patio. Lush greenery enhances the space, with a clear sky overhead. A balcony is visible from the second floor, overlooking the inviting pool area.
Guesthouse in Sam Hughes

Sam Hughes oasis with pool, close to U of A

4.92 out of 5 average rating, 243 reviews
Top guest favorite
A charming exterior view of the guest house is presented, featuring colorful potted plants arranged along the pathway. A cozy seating area with white chairs is visible beside the entrance adorned with a vibrant door, framed by warm lighting and lush greenery.
Guesthouse in Tucson

Private Tucson Desert Guest House Getaway

4.97 out of 5 average rating, 889 reviews
Top guest favorite
A tranquil rooftop patio is depicted, featuring a round table and two black metal chairs. The backdrop showcases the majestic mountains, softly illuminated by the evening light, with lush vegetation extending into the distance.
Guesthouse in Tucson

Pet Friendly Casita with striking Mountain View’s

4.93 out of 5 average rating, 299 reviews
Top guest favorite
A tranquil outdoor space features a stone fountain surrounded by potted plants and low shrubs. A small table with two chairs is set on a tiled patio. A blue staircase leads to the upper level, and colorful flowers add a vibrant touch to the scenery.
Guesthouse in Tucson

Rooftop Casita in Civano Private Patio & Mtn Views

5.0 out of 5 average rating, 175 reviews
Top guest favorite
A fenced outdoor area features a serene pool with a natural stone hot tub beside it. The pool is surrounded by artificial grass and desert landscaping, with a few shaded lounge chairs nearby, creating a tranquil space for relaxation.
Guesthouse in Tucson

Charming Private Oasis Casita with Pool & Hot Tub

5.0 out of 5 average rating, 221 reviews
Guest favorite
The exterior of the cottage features warm, wooden siding with a unique sloped roof. A welcoming front porch is furnished with two rocking chairs, inviting guests to enjoy the surrounding desert landscape. A vehicle is parked nearby on a gravel driveway.
Guesthouse in Tucson

The Cottage

4.92 out of 5 average rating, 179 reviews
Top guest favorite
The entrance features a wooden door framed by a decorative overhang. Flanking the door are large windows that allow natural light, while surrounding vegetation adds a touch of greenery. Colorful tile accents are visible on the steps leading to the door.
Guesthouse in Tucson

Artistic Desert Guesthouse Retreat

4.96 out of 5 average rating, 231 reviews

Guest house rentals with a patio

Top guest favorite
An outdoor patio area is shown, featuring a hot tub and a grill alongside a gravel-covered space. A dining table with chairs is arranged nearby, and a privacy fence encloses the area, while a colorful sky enhances the evening setting.
Guesthouse in Tucson

Midtown-New Constr/Hot Tub/Full Kitchen/Private

4.96 out of 5 average rating, 116 reviews
Guest favorite
A modern kitchen is showcased with wooden cabinetry and dark appliances. A spacious white countertop extends into a breakfast bar with two wooden stools. A door leading to the outside is visible, framed by natural light, creating an open and inviting atmosphere.
Guesthouse in Tucson

The Coop- Luxury guest house with ideal location

4.96 out of 5 average rating, 252 reviews
Guest favorite
A rustic adobe exterior is adorned with a wooden door framed by natural wood accents. Prickly pear cacti grow on either side, set against a textured adobe wall. Pebbles cover the ground, complementing the earthy tones of the structure.
Guesthouse in Tucson

Adobe Carriage House downtown Chiminea+Ramada

4.94 out of 5 average rating, 179 reviews
Guest favorite
The two-story guesthouse features a Southwestern stucco exterior and large windows that invite natural light. A pool sits in the foreground, surrounded by a patio area furnished with outdoor seating and lush greenery. The outdoor space offers a quiet, relaxing atmosphere.
Guesthouse in Tucson

Sunshine Loft

4.9 out of 5 average rating, 253 reviews
Guest favorite
The exterior of the guest house is showcased, featuring crisp white walls and a modern blue roof. Large windows allow natural light to illuminate the entrance, which is bordered by minimalist plants in black pots. A concrete porch extends across the front.
Guesthouse in Tucson

Dunbar Springs Desert Oasis Guesthouse

4.89 out of 5 average rating, 292 reviews
Top guest favorite
A well-appointed guest room features a wooden king-size bed with crisp white linens and a modern ceiling fan. A workspace with a desk and chair is present, along with a wall mirror and bedside lamps. Natural light brightens the space, enhancing the neutral color palette.
Guesthouse in Tucson

*Prime Location: King Suite Guest House!*

4.98 out of 5 average rating, 130 reviews
Guest favorite
Guesthouse in Tucson

CasaJaguarTucson Blanca | near Saguaro Nat Park

4.89 out of 5 average rating, 126 reviews
Top guest favorite
The exterior view features a vibrant blue wall of the casita, complemented by a contrasting red roof. A white door with a glass panel provides access, framed by a small window. A brick pathway leads from the door through the surrounding greenery.
Guesthouse in Tucson

Casita with Heated Salt Water Pool & Solar Power

4.98 out of 5 average rating, 151 reviews

Guest house rentals with a washer and dryer

Guest favorite
The exterior of a guest house is showcased, featuring a covered patio with seating and a textured stucco facade. Surrounding vegetation includes desert plants, under a clear blue sky. A gravel area is noted, providing a natural and unobtrusive landscape.
Guesthouse in Tucson

Desert Getaway 2 Bedroom Guest House

4.97 out of 5 average rating, 152 reviews
Top guest favorite
A cozy outdoor seating area is situated in front of the casita, featuring a comfortable wicker loveseat and a small circular table. The entrance is framed by double French doors, and desert landscaping includes native plants, creating a sense of privacy in a tranquil environment.
Guesthouse in Tucson

The Outpost

5.0 out of 5 average rating, 208 reviews
Superhost
A light-colored entrance features a door with a semi-circular window. Two wooden chairs are positioned on the steps, accompanied by a small table. Natural elements, including a tree with string lights, frame the entrance, creating a welcoming outdoor space.
Guesthouse in Tucson

🌵 Central Desert Oasis 3 🌵

4.93 out of 5 average rating, 270 reviews
Top guest favorite
The image displays a serene garden area, featuring a variety of lush plants and cacti. A pathway made of bricks leads towards a shaded patio, which is supported by brightly painted columns. The garden is designed with natural elements, creating a peaceful outdoor ambiance.
Guesthouse in Tucson

Extra-Spacious 1BR Guesthouse Close to UA

5.0 out of 5 average rating, 189 reviews
Guest favorite
A modern living area features a brown leather sofa placed against a white wall, complemented by a multi-colored area rug beneath. A flat-screen television is positioned on a wooden media console. Natural light enters through a nearby window adorned with blinds, giving the space a bright ambiance.
Guesthouse in Tucson

Horse house

4.93 out of 5 average rating, 122 reviews
Guest favorite
The saltwater pool features a clear, shimmering surface, surrounded by a spacious deck. Two lounge chairs with wooden frames are positioned nearby for relaxation, while potted plants add a touch of greenery along the perimeter.
Guesthouse in Sam Hughes

Blue Lake Boutique Hotel

4.95 out of 5 average rating, 228 reviews
Top guest favorite
A cozy living area features vibrant orange sofas surrounding a central coffee table on wheels. Warm ambient lighting is provided by a hanging lamp and table lamps. Soft textures and earthy tones are complemented by natural light from a window, creating an inviting space for relaxation.
Guesthouse in Tucson

Fun Retro Cottage

4.98 out of 5 average rating, 165 reviews
Guest favorite
Guesthouse in Tucson

Cozy Casita 1.3 miles to UofA

4.9 out of 5 average rating, 309 reviews

Other guesthouse vacation rentals

Top guest favorite
A comfortable living area is presented, featuring a brown leather sofa opposite a circular wooden coffee table. A colorful area rug adds texture to the floor, while a floor lamp and a large mirror enhance the inviting ambiance. Bright yellow curtains frame a nearby window.
Guesthouse in Tucson

The Southwest Knest

4.97 out of 5 average rating, 529 reviews
Guest favorite
The spacious room features a queen bed beneath a beamed ceiling with warm lighting. A cozy seating area includes an armchair and a footrest. A wooden desk and chairs occupy one side, while an air conditioning unit and an electric fireplace are visible on opposite walls.
Guesthouse in Tucson

Casa Rosa (Desert Oasis Casita w/ Mt Lemmon Views)

4.91 out of 5 average rating, 413 reviews
Top guest favorite
Guesthouse in Sam Hughes

Hues Casita - Airy Studio Near U of A

4.95 out of 5 average rating, 132 reviews
Top guest favorite
A private patio area features a large black umbrella, providing shade over two wicker lounge chairs arranged around a round table. Surrounding greenery adds a sense of seclusion, while various plants and a fire pit enhance the outdoor ambiance.
Guesthouse in Tucson

Spanish Bungalow Casita with Private Patio

4.92 out of 5 average rating, 539 reviews
Top guest favorite
Guesthouse in Tucson

Private Casita in Casas Adobes

4.92 out of 5 average rating, 232 reviews
Top guest favorite
A cozy sleeping area features a spacious bed topped with light-colored linens and decorative pillows. Warm tones are presented on the accent wall, while bedside lighting and a simple nightstand enhance the inviting space. Natural light filters in through a nearby window, contributing to a bright atmosphere.
Guesthouse in Tucson

Charming Desert Guesthouse

4.92 out of 5 average rating, 164 reviews
Top guest favorite
A separate guest house is situated amidst a lush green lawn, framed by desert vegetation. Earthy-toned walls harmonize with the surrounding landscape. A patio area is visible, adorned with potted plants, offering an inviting spot to relax outdoors.
Guesthouse in Tucson

Peaceful Desert Setting

4.98 out of 5 average rating, 131 reviews
Guest favorite
The exterior of the studio is highlighted by large glass doors, providing ample natural light. A small outdoor seating area with a table and two chairs is positioned on a concrete patio, surrounded by desert landscaping and potted plants.
Guesthouse in Tucson

Copper House - Mid-century Modern Gem near U of A.

4.85 out of 5 average rating, 239 reviews

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