
Guesthouse vacation rentals near Saguaro National Park
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Top-rated guesthouse rentals near Saguaro National Park
Guests agree: these stays are highly rated for location, cleanliness, and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

RetroTrek Bungalow Private-Fenced-Cozy
Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

Knightly's Ranch Guesthouse
A beautiful, secure, private home on a fenced & gated private 5 acre property that sits adjacent to Saguaro National Park with horse & hiking paths galore. Access to trails, golfing, fishing, birding, photography, local biking and horseback riding. Desert landscape with abundant Tucson wildlife, it's secluded but easy access to anywhere in Tucson. Western setting & user-friendly site. A ranch on a dirt road with horses, dogs & chickens, bbq, stargazing & sunsets. The mountains & moon are yours!

Little Hummingbird House -An Enchanted Food Forest
Casita Colibrí (Little Hummingbird House) - lush oasis flourishing with life nestled in The Enchanted Food Forest-home to fruit trees, gardens, koi pond, chickens, giant tortoise, dogs, cats, and its namesake, hummingbirds in Tucson's heart. Enjoy fresh eggs & fruit, wander garden paths, relax poolside, or watch koi beneath the waterfall. It's not just a place to stay—it’s a special place to slow down, reconnect, and breathe in beauty and life, where peace & magic are woven into every corner.

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Tranquil Bears Path Casita
This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.

Cozy midtown guesthouse
A cozy, one-bedroom retreat on a peaceful bike boulevard. Features a queen bed, futon, and fully equipped kitchen. Minutes from the university via dedicated bike boulevards, close to city conveniences, ideal for work or relaxation. We offer a relaxed stay with minimal check-out tasks and transparent pricing. Amenities include a full kitchen, bathroom essentials, washer/dryer, WIFI, TV, AC/heat. Street parking available. Cleaned and disinfected regularly. Book your tranquil escape now!

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

Central and Stylish Midcentury Pool House
Our beautiful adobe pool house is a Tucson gem. Comfortable queen bed, fireplace, and stylish modern furnishings with large windows looking out to trees and sparkling pool. Vaulted ceilings and natural light make for a restful space. Located in historic Jefferson Park, it’s a midtown oasis close to the UofA and two blocks from the UMC/Banner Medical Center. Midtown/University location allows for convenient access to all of Tucson. *Newly improved high speed WiFi 11/1/2021

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

TREAT GUEST HOUSE Private, Quiet, Comfortable
Himmel Park pool is very close by and open in June & July. Welcome to a one-of-a-kind guesthouse created by a Swiss-born professional photographer and freelance artist. This attractive open studio space is part of my "Gesamtkunstwerk" (entire body of work), still in flux. Featuring murals and curated pieces from across a lifelong creative journey. Thoughtfully designed with passion and purpose, the space offers both inspiration and comfort in the heart of Tucson.

Time Capsule in the Sonoran Desert
Vibrant space-age cabin on an 11-acre desert art sanctuary near Saguaro National Park, 35 mins from Tucson! Features WiFi, AC/heat, outdoor bathroom deck & eco-amenities. Sits 15 yards from Groovy Glamper. 🚫 NO PETS/ESAs (Service Animals welcome). Delicate art decor makes this space strictly UNSUITABLE for children/minors. ⚠️ IMPORTANT: Before booking, note that check-in is strictly in person and no later than 10:00 PM. No exceptions!
Popular amenities for guesthouse rentals near Saguaro National Park
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- Mount Lemmon
- Mt Lemmon Ski Valley
- University of Arizona
- Sabino Canyon
- University of Arizona
- Arizona-Sonora Desert Museum
- Tumamoc Hill
- Tucson Convention Center
- Patagonia Lake State Park
- Kartchner Caverns State Park
- Biosphere 2
- Sabino Canyon Recreation Area
- Tucson Botanical Gardens
- Titan Missile Museum
- Reid Park Zoo
- Catalina State Park
- Tucson Museum of Art
- Mission San Xavier del Bac
- Pima Air & Space Museum
- Rialto Theatre
- Tumacacori National Historical Park
- Sonoita Vineyards
- Children's Museum Tucson
- Trail Dust Town





