
Guesthouse vacation rentals in Pima County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Pima County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

RetroTrek Bungalow Private-Fenced-Cozy
Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

Little Hummingbird House -An Enchanted Food Forest
Casita Colibrí (Little Hummingbird House) - lush oasis flourishing with life nestled in The Enchanted Food Forest-home to fruit trees, gardens, koi pond, chickens, giant tortoise, dogs, cats, and its namesake, hummingbirds in Tucson's heart. Enjoy fresh eggs & fruit, wander garden paths, relax poolside, or watch koi beneath the waterfall. It's not just a place to stay—it’s a special place to slow down, reconnect, and breathe in beauty and life, where peace & magic are woven into every corner.

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Peaceful Desert Oasis in Central Tucson Foothills
Newly renovated guest home located in a quiet central area in the Catalina Foothills. Trails and biking in our backyard, 10-15 min drive to hiking/parks, downtown and UofA! Away from everything and yet conveniently close to everything! Enjoy beautiful mountain views and professional landscaping. Well equipped kitchen with washer/dryer and a cozy fireplace and desk in the master bedroom. Lots of privacy from the main home. Stocked with all your amenities needed for a cozy and comfortable stay.

Private Tucson Desert Guest House Getaway
This guest house is a pleasant desert retreat in Northeast Tucson, nestled on a large property with spectacular views of the Catalina Mountains. Minutes from from Sabino Canyon, Mt. Lemmon, and close to sumptuous dining. Guests will enjoy a recently space which includes a kitchenette complete with a microwave, coffee-maker, toaster oven, refrigerator, and more. Large bathroom and closet. Also available are a pool, BBQ grill, outdoor seating, and play yard. Laundry available upon request.

Tranquil Bears Path Casita
This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.

Casita de Suenos
Replenish * Re-calibrate * Reconnect.. Welcome to our little house of dreams! You have found the perfect leaping off point to explore all this region has to offer. Nestled snugly between the Patagonia and Santa Rita mountains, our casita sits at just under 5,000 ft, making it temperature perfect almost year round. Enjoy our 38 acres and private hiking trails right out the front door with endless possibilities for adventure. Recharge, Rejuvenate, and Revel in our cozy, clean, quite space.
LocationHospitality

Cozy midtown guesthouse
A cozy, one-bedroom retreat on a peaceful bike boulevard. Features a queen bed, futon, and fully equipped kitchen. Minutes from the university via dedicated bike boulevards, close to city conveniences, ideal for work or relaxation. We offer a relaxed stay with minimal check-out tasks and transparent pricing. Amenities include a full kitchen, bathroom essentials, washer/dryer, WIFI, TV, AC/heat. Street parking available. Cleaned and disinfected regularly. Book your tranquil escape now!
LocationCleanlinessComfort

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

The Coop- Luxury guest house with ideal location
This luxury guest home was originally a chicken coop for a farmer over 60 years who owned the majority of the land in the area. With an addition and a complete renovation, we have designed this for the perfect vacation rental ideally located in Tucson. 15 minutes to Banner and the U of A. 10 minutes to Oro Valley or the freeway. The stylish guest home is separated from our home and designed with privacy in mind. Enjoy this brand new house for your stay with experienced hosts.

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).
Popular amenities for Pima County guesthouse rentals
Family-friendly guest house rentals

Charming Private Oasis Casita with Pool & Hot Tub

Sam Hughes oasis with pool, close to U of A

Knightly's Ranch Guesthouse

Golden moments in Oro Valley/Tucson

Saguaro Courtyard Retreat near National Park

The Cottage

Charming, Cozy Casita with Pool - low summer rates

Cozy Thunder Mountain Ranch bunkhouse experience
Guest house rentals with a patio

Midtown-New Constr/Hot Tub/Full Kitchen/Private

Dunbar Springs Desert Oasis Guesthouse

*Prime Location: King Suite Guest House!*
NearbyIndoor spaces

Adobe Carriage House downtown Chiminea+Ramada
Outdoor spacesIndoor spaces

Sunshine Loft

Southwest Solitude
Cleanliness

Coyote Cavern: A Southwestern High Desert Retreat

Midtown House near TMC & UofA•Fast WiFi •Self ChIn
Guest house rentals with a washer and dryer

TREAT GUEST HOUSE Private, Quiet, Comfortable

Studio in the Saguaro Forest

Charming Indoor Jacuzzi & outdoor heated pool

Serene Desert Casita - No Hidden fees Pets welcome

Big, Beautiful Guest House!

Extra-Spacious 1BR Guesthouse Close to UA

Blue Lake Boutique Hotel

Desert Getaway 2 Bedroom Guest House
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- University of Arizona
- University of Arizona
- Arizona-Sonora Desert Museum
- Tucson Convention Center
- Tumamoc Hill
- Titan Missile Museum
- Tucson Botanical Gardens
- Reid Park Zoo
- Tucson Museum of Art
- Mission San Xavier del Bac
- Pima Air & Space Museum
- Rialto Theatre
- Tumacacori National Historical Park
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- Mini Time Machine Museum of Miniatures
- Picacho Peak State Park
- Tubac Presidio State Historic Park
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- Gene C Reid Park
- Rooster Cogburn Ostrich Ranch
- Red Hills Visitor Center
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