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Vacation rentals in Santa Cruz

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A comfortable living area is depicted, featuring a dark brown sofa with decorative pillows and a wooden coffee table. A large television mounted on the wall displays a nature scene. Art pieces and family photos are arranged on the walls, enhancing the homely feel.
Home in Santa Cruz
4.98 out of 5 average rating, 208 reviews

Casa de Luz, fully equipped with parking.

Cozy retreat in the heart of the Colchagua Valley Discover a warm, bright space full of positive energy in Santa Cruz. A cozy equipped house, ideal for resting, reconnecting or enjoying the wonders of the valley: vineyards, history, gastronomy and nature. Here everything is designed to make you feel at home and that special touch that only a home with soul can offer. Wifi, full kitchen. Steps from the best vineyards Ideal for couples, families or solo getaways.

Guest favorite
A charming rustic chalet is set against a backdrop of rolling hills. The exterior features wooden beams and large glass windows, allowing for plenty of natural light. A hammock, patio furniture, and decorative plants enhance the inviting outdoor space.
Cabin in Palmilla
4.96 out of 5 average rating, 54 reviews

Colchagua Chalet - Mosto Lodge

Chalet Colchagua, es un alojamiento rústico colonial inspirado en la región vinícola. Es ideal para sumergirse en el mundo de la viticultura, ya que se encuentra rodeado de viñedos, restaurantes y pura tranquilidad. En el exterior, se encuentran un quincho, una parrilla y una piscina compartida con el Chalet Colchagua. Centro Santa Cruz -25min Peralillo - 20min Jumbo - 25min Museo Cardoen - 25min Vino Bello - 20min Viu Manet - 25min Fuegos de Apalta - 30min

Guest favorite
Home in Palmilla
5 out of 5 average rating, 8 reviews

Beautiful lodge with panoramic view in Santa Cruz

“Despierta frente a los viñedos en Colchagua” Disfruta de la sofisticación de nuestro lodge de 3 dormitorios, diseñado para los amantes del buen vino. Nuestra cocina de concepto abierto con isla central es el escenario perfecto para una cata privada, conectando con una amplia terraza donde el valle de Colchagua se rinde a tus pies. Ubicación inmejorable frente a viña MontGras. Te esperamos con una botella de vino de cortesía y datos para tours.

Top guest favorite
Home in Isla de Yáquil
5 out of 5 average rating, 32 reviews

Colchagua industrial loft among vineyards

Sleep in a loft among Cabernet Sauvignon vineyards in the Colchagua Valley You will enjoy a breakfast included in the rate with products from the countryside. You can go horseback riding as a couple with a guide accompanying you You have bicycles to ride In the loft you have firewood to use the fireplace or an outdoor stove Enjoy a private quincho with a charcoal grill and a large table Enjoy with horses, sheep, chickens 24-hour check-in

Top guest favorite
Guesthouse in San Vicente de Tagua Tagua
4.97 out of 5 average rating, 66 reviews

TyM House

Refugio con Vista Panorámica al Valle Despierta cada mañana con una vista privilegiada del valle, rodeado de un entorno natural que invita al descanso y la desconexión. Lo que ofrecemos: Espacios cálidos y confortables para un descanso pleno. Jacuzzi al aire libre para disfrutar bajo las estrellas. Fogón perfecto para compartir historias o una copa de vino. Entorno natural que invita a caminar, respirar profundo y reconectar.

Guest favorite
A comfortable living area features a light-colored sofa with decorative cushions, alongside a leather armchair. A wooden coffee table sits in front, and palm tree artwork decorates the wall. Large windows allow natural light to enter, and a view of the open kitchen is visible in the background.
Home in Santa Cruz
4.88 out of 5 average rating, 25 reviews

Casa Parrón

Have fun with the whole family in this stylish accommodation. Cozy house with an excellent location and ample parking Enjoy a comfortable and relaxing stay in this spacious house, ideal for families or groups of friends. It accommodates up to eight people. In addition, the house has ample parking and is in an excellent location, perfect for a quiet getaway or an extended stay. We look forward to seeing you!

Guest favorite
A two-story colonial-style house is featured, with a terracotta exterior and terracotta tile roof. A wooden gate marks the entrance, and a small tree is positioned next to the wall, adding a touch of greenery against the bright blue sky.
Home in Santa Cruz
4.87 out of 5 average rating, 215 reviews

Just like home...

Two-story colonial-style house, tiles, wooden gate closure. Decorated mostly with Raulí furniture. Cozy atmosphere, quiet neighborhood, quiet, ideal for resting away from noise. Close to Colchagua Casino, museum, plaza, bars, pub and restaurants. Uber contact for a known and trusted person. The house has private parking for two vehicles. Air conditioning, Wi-Fi, Netflix, and terrace for grilling.

Guest favorite
Two boutique cabins are surrounded by well-maintained gardens featuring gravel paths and greenery. A small seating area with white chairs is visible near a decorative barrel, while birch trees add to the serene outdoor ambiance.
Farm stay in Santa Cruz
4.93 out of 5 average rating, 27 reviews

Tiny Cabins No. 2 (two people), breakfast included

We have two premium boutique cabins for two people, fully equipped, no kitchen, air conditioning, safe, minibar, hairdryer, 42-inch HD satellite TV, Wi-Fi, tourist advice, near restaurants and vineyards in the area. In addition to a large swimming pool and an excellent welcome wine. INCLUDES BREAKFAST, no maid service

Top guest favorite
The exterior of the lodge is presented, featuring a modern design with large glass windows. The structure is supported by distinctive angled beams, surrounded by landscaped gardens with various plants and a gravel pathway. Open seating areas are visible on the spacious deck.
Home in Santa Cruz
4.97 out of 5 average rating, 264 reviews

LODGE ACACIA CAVEN

Lodge Acacia Caven Un espacio de lleno de tranquilidad y confort ,conectado con la naturaleza, a 4 km del centro de de ciudad de Santa Cruz, ubicado en parcela de agrado privada. Casa de 100 metros cuadrados con Hot Tub externo, Terraza, Fogón, estacionamiento propio, zona para asado y entrada independiente.

Top guest favorite
A spacious outdoor area is framed by tall palm trees, offering a lush green lawn. Two buildings are visible, with one featuring large glass doors and a covered porch. The other is a charming structure with a traditional roof, surrounded by well-maintained plants.
Home in Santa Cruz
4.97 out of 5 average rating, 100 reviews

Casa de Campo in Santa Cruz

Modern country house very close to Santa Cruz. 4 bedrooms, master bedroom en suite. Master and second bedroom with a double bed. In the second bedroom, the bed can be separated into two singles. Many walks and sights along the wine route. 5 kilometers from the square.

Top guest favorite
An outdoor space features a serene pool surrounded by carefully arranged stones and rocks. Lounge chairs are placed along the poolside. Lush green grass extends throughout the area, while expansive windows offer views of the nearby vineyards and mountains in the background.
Home in Santa Cruz
4.96 out of 5 average rating, 24 reviews

House in Apalta

En el Valle de Apalta, que a su vez está inmerso en el corazón del Valle de Colchagua, se encuentra esta adorable casa de fascinante arquitectura, rodeada de viñedos y afamadas viñas que dan origen a los vinos más premiados de Chile.

Guest favorite
A cozy living area is showcased with a sleek black sofa facing a mounted television. A wooden coffee table and a side table with decorative items are positioned nearby. Natural light filters through sheer window coverings, illuminating the space.
Home in Colchagua
4.93 out of 5 average rating, 54 reviews

Colchagua Stay. Live your experience in Santa Cruz

Colchagua Stay. Come and enjoy this beautiful place called Santa Cruz. A quiet place to feel at home and is located 3 minutes from downtown by vehicle, close to a restaurant, vineyards, supermarket. Enjoy the Colchagua Valley.

Popular amenities for Santa Cruz vacation rentals

When is the best time to visit Santa Cruz?

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Frequently Asked Questions

  • Are there family-friendly vacation rentals in Santa Cruz?

    Santa Cruz has more than 60 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • How much does it cost to stay in bed and breakfast rentals in Santa Cruz?

    Experience the best of Santa Cruz with our bed and breakfast rentals, starting at about $20 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there pet-friendly vacation rentals in Santa Cruz?

    Four-legged friends are welcome in Santa Cruz. Choose from more than 30 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in Santa Cruz?

    Yes! Work meets play with ease at over 50 vacation rentals in Santa Cruz featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there Santa Cruz vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 30 vacation homes with pools in Santa Cruz, available on Airbnb. Make a splash and soak up the sun in style!

  • Do house rentals in Santa Cruz have air conditioning?

    Absolutely! We offer over 20 house rentals with air conditioning in Santa Cruz. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Santa Cruz have a kitchen?

    Absolutely! We offer over 60 house rentals with a kitchen in Santa Cruz. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in Santa Cruz have wifi?

    Absolutely! We offer over 60 house rentals with wifi in Santa Cruz. Enjoy a tailored experience with all the comforts you desire.

  • Do cabin rentals in Santa Cruz have free parking?

    Absolutely! We offer over 10 cabin rentals with free parking in Santa Cruz. Enjoy a tailored experience with all the comforts you desire.

  • What are the most popular amenities for Bed And Breakfast Rentals in Santa Cruz?

    Enhance your stay in our Bed And Breakfast Rentals with the most popular amenities: over 10 homes with free parking, over 10 homes with a kitchen, over 10 homes with wifi, and more. Indulge in the ultimate retreat, tailored to your preferences.

Quick stats about vacation rentals in Santa Cruz

  • Total vacation rentals

    Explore 140 vacation rentals in Santa Cruz

  • Verified guest reviews

    Over 2,570 verified reviews to help you choose

  • Family-friendly vacation rentals

    60 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 30 rentals that welcome pets

  • Vacation rentals with a pool

    30 properties feature pools

  • Rentals with dedicated workspaces

    50 properties have a dedicated workspace

  • Wi-Fi availability

    120 of Santa Cruz vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santa Cruz rentals

  • 4.8 Average rating

    Santa Cruz stays are highly rated by guests—averaging 4.8 out of 5!

  1. Airbnb
  2. Chile
  3. O'Higgins
  4. Colchagua
  5. Santa Cruz