
House vacation rentals in Santa Cruz
Find and book unique houses on Airbnb
Quick stats about house rentals in Santa Cruz

Total vacation rentals
Explore 70 vacation rentals in Santa Cruz

Verified guest reviews
Over 1,700 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wi-Fi availability
50 of Santa Cruz vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santa Cruz rentals

4.8 Average rating
Santa Cruz stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Santa Cruz
Guests agree: these houses are highly rated for location, cleanliness, and more.

Boutique House in Private Vineyard in Apalta
@boutiqueapalta Wake up surrounded by Chile's most renowned wine valley. This house combines contemporary design, nature and the unique experience of staying in an active vineyard. Designed by Teodoro Fernández, National Architecture Prize, it offers a perfect blend of rural and modern with an environment abundant in vegetation. 8 km from S. Cruz, you will be surrounded by the most prestigious vineyards in the country, a privileged environment that is difficult to find in another area of Chile.

La Puerta Cabin
Escape to the heart of the Colchagua Valley Enjoy a comfortable and quiet stay in our cabin for 4 people, located just 7 minutes from downtown Santa Cruz. Ideal for those looking to disconnect, perfect for exploring local cuisine, visiting boutique vineyards and discovering everything the Colchagua Valley has to offer. The cabin is new and runs on sustainable energy. Its peaceful surroundings and proximity to outstanding restaurants will make your experience unforgettable.

House on a private vineyard with panoramic views
Contemporary designer house on an exclusive private vineyard in the Apalta Valley. Accommodating up to 6 people, it offers spacious rooms, elegant décor, and floor-to-ceiling windows with spectacular views of vineyards and hills. A unique retreat to unwind in style, enjoy unforgettable sunsets, and have a premium experience in total privacy. Minutes from the main vineyards, such as Viña Montes, Clos de Apalta, and many more. Two minutes from the Fuegos de Apalta restaurant.

Casa de Campo in Santa Cruz
Casa de Campo en la Comuna Santa Cruz Enjoy nature and tranquility in our beautiful country house! Located in the Los Boldos sector, Route I-730 (Isla de Yaquil road), just 5 minutes from downtown Santa Cruz. - 3 large bedrooms with comfortable beds - 2 full bathrooms -Living room with woods - Equipped kitchen -WiFi - A spacious garden and parking for several vehicles - Just 3 minutes from the Casa Colchagua, Los Poetas, Prapes Sushi, and Vino Bello restaurants

Casa de Luz, fully equipped with parking.
Cozy retreat in the heart of the Colchagua Valley Discover a warm, bright space full of positive energy in Santa Cruz. A cozy equipped house, ideal for resting, reconnecting or enjoying the wonders of the valley: vineyards, history, gastronomy and nature. Here everything is designed to make you feel at home and that special touch that only a home with soul can offer. Wifi, full kitchen. Steps from the best vineyards Ideal for couples, families or solo getaways.

Colchagua Farmstays
Sleep in a loft among Cabernet Sauvignon vineyards in the Colchagua Valley You will enjoy a breakfast included in the rate with products from the countryside. You can go horseback riding as a couple with a guide accompanying you You have bicycles to ride In the loft you have firewood to use the fireplace or an outdoor stove Enjoy a private quincho with a charcoal grill and a large table Enjoy with horses, sheep, chickens 24-hour check-in

Casa Parrón
Have fun with the whole family in this stylish accommodation. Cozy house with an excellent location and ample parking Enjoy a comfortable and relaxing stay in this spacious house, ideal for families or groups of friends. It accommodates up to eight people. In addition, the house has ample parking and is in an excellent location, perfect for a quiet getaway or an extended stay. We look forward to seeing you!

Just like home...
Two-story colonial-style house, tiles, wooden gate closure. Decorated mostly with Raulí furniture. Cozy atmosphere, quiet neighborhood, quiet, ideal for resting away from noise. Close to Colchagua Casino, museum, plaza, bars, pub and restaurants. Uber contact for a known and trusted person. The house has private parking for two vehicles. Air conditioning, Wi-Fi, Netflix, and terrace for grilling.

Cozy house minutes from downtown
Cozy house a few minutes from downtown, ideal for a comfortable and quiet stay. Features air conditioning, private parking, and an electric car charger (use at extra cost). The master bedroom has a private bathroom, offering greater comfort and privacy. An excellent choice for both leisure and business trips, with everything you need to feel at home.

Garden House
Cozy typical Chilean house, in the heart of Santa Cruz, inside the Viña Laura Hartwig. Large spaces, unique details and a vineyard environment. Ideal for enjoying the countryside with all the comforts and warmth. Perfect for those looking to experience nature, the charm of the Colchagua Wine Route and the Chilean countryside.

LODGE ACACIA CAVEN
Lodge Acacia Caven Un espacio de lleno de tranquilidad y confort ,conectado con la naturaleza, a 4 km del centro de de ciudad de Santa Cruz, ubicado en parcela de agrado privada. Casa de 100 metros cuadrados con Hot Tub externo, Terraza, Fogón, estacionamiento propio, zona para asado y entrada independiente.

Casa Sta. Cruz Valle-Colchagua Vineyard: Estc. BBQ Area
Casa Viñastay is located in the Colchagua Valley and on the wine route, 500 meters from the casino, the Colchagua Museum and the center of Santa Cruz. Ideal for teleworking with fast Wi-Fi, air conditioning, and a wood-burning stove. Firewood is available for its operation.
Popular amenities for Santa Cruz house rentals
House rentals with a pool

Casa Santa Cruz, Colchagua Valley, Chomedague

Malva House, Palmilla, Santa Cruz

Country house in the heart of the city

Country house in Colchagua

Country House - François Lurton

Casas Santa Cruz 1

Country House in Pichidegua

Casa Aromo
Weekly house rentals

Cabin in Colchagua Valley

Double room with twin beds and a private bathroom

“El Descanso” family plot

Family home, quiet place

Cabin in Los Boldos, second floor

Comfortable and quiet house.

Casa El Huique

Santa Cruz, Colchagua Valley
Private house rentals

comfortable house, large garden with pool.

Your ideal retreat to disconnect in Santa Cruz

5-Bedroom Plot near Marchigue Wine Route

Palmilla country house.

House with a view, Colchagua Valley, Lolol

Furnished house for rent, very good location

Accommodation in Santa Cruz

House in the heart of San Vicente
When is the best time to visit Santa Cruz?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 228 | ﺩ.ﺇ 213 | ﺩ.ﺇ 231 | ﺩ.ﺇ 209 | ﺩ.ﺇ 202 | ﺩ.ﺇ 213 | ﺩ.ﺇ 209 | ﺩ.ﺇ 206 | ﺩ.ﺇ 198 | ﺩ.ﺇ 209 | ﺩ.ﺇ 213 | ﺩ.ﺇ 202 |
| Avg. temp | 22°C | 21°C | 19°C | 14°C | 11°C | 9°C | 8°C | 10°C | 12°C | 14°C | 18°C | 20°C |
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