
House vacation rentals in Santa Cruz
Find and book unique houses on Airbnb
Quick stats about house rentals in Santa Cruz

Total vacation rentals
Explore 70 vacation rentals in Santa Cruz

Verified guest reviews
Over 1,700 verified reviews to help you choose

Family-friendly vacation rentals
40 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wi-Fi availability
50 of Santa Cruz vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santa Cruz rentals

4.8 Average rating
Santa Cruz stays are highly rated by guests—averaging 4.8 out of 5!
Top-rated house rentals in Santa Cruz
Guests agree: these houses are highly rated for location, cleanliness, and more.

La Puerta Cabin
Escape to the heart of the Colchagua Valley Enjoy a comfortable and quiet stay in our cabin for 4 people, located just 7 minutes from downtown Santa Cruz. Ideal for those looking to disconnect, perfect for exploring local cuisine, visiting boutique vineyards and discovering everything the Colchagua Valley has to offer. The cabin is new and runs on sustainable energy. Its peaceful surroundings and proximity to outstanding restaurants will make your experience unforgettable.

House on a private vineyard with panoramic views
Contemporary designer house on an exclusive private vineyard in the Apalta Valley. Accommodating up to 6 people, it offers spacious rooms, elegant décor, and floor-to-ceiling windows with spectacular views of vineyards and hills. A unique retreat to unwind in style, enjoy unforgettable sunsets, and have a premium experience in total privacy. Minutes from the main vineyards, such as Viña Montes, Clos de Apalta, and many more. Two minutes from the Fuegos de Apalta restaurant.

Casa de Luz, fully equipped with parking.
Cozy retreat in the heart of the Colchagua Valley Discover a warm, bright space full of positive energy in Santa Cruz. A cozy equipped house, ideal for resting, reconnecting or enjoying the wonders of the valley: vineyards, history, gastronomy and nature. Here everything is designed to make you feel at home and that special touch that only a home with soul can offer. Wifi, full kitchen. Steps from the best vineyards Ideal for couples, families or solo getaways.

Beautiful lodge with panoramic view in Santa Cruz
“Despierta frente a los viñedos en Colchagua” Disfruta de la sofisticación de nuestro lodge de 3 dormitorios, diseñado para los amantes del buen vino. Nuestra cocina de concepto abierto con isla central es el escenario perfecto para una cata privada, conectando con una amplia terraza donde el valle de Colchagua se rinde a tus pies. Ubicación inmejorable frente a viña MontGras. Te esperamos con una botella de vino de cortesía y datos para tours.

Colchagua Farmstays
Sleep in a loft among Cabernet Sauvignon vineyards in the Colchagua Valley You will enjoy a breakfast included in the rate with products from the countryside. You can go horseback riding as a couple with a guide accompanying you You have bicycles to ride In the loft you have firewood to use the fireplace or an outdoor stove Enjoy a private quincho with a charcoal grill and a large table Enjoy with horses, sheep, chickens 24-hour check-in

Casa Parrón
Have fun with the whole family in this stylish accommodation. Cozy house with an excellent location and ample parking Enjoy a comfortable and relaxing stay in this spacious house, ideal for families or groups of friends. It accommodates up to eight people. In addition, the house has ample parking and is in an excellent location, perfect for a quiet getaway or an extended stay. We look forward to seeing you!

Just like home...
Two-story colonial-style house, tiles, wooden gate closure. Decorated mostly with Raulí furniture. Cozy atmosphere, quiet neighborhood, quiet, ideal for resting away from noise. Close to Colchagua Casino, museum, plaza, bars, pub and restaurants. Uber contact for a known and trusted person. The house has private parking for two vehicles. Air conditioning, Wi-Fi, Netflix, and terrace for grilling.

Cozy house minutes from downtown
Cozy house a few minutes from downtown, ideal for a comfortable and quiet stay. Features air conditioning, private parking, and an electric car charger (use at extra cost). The master bedroom has a private bathroom, offering greater comfort and privacy. An excellent choice for both leisure and business trips, with everything you need to feel at home.

LODGE ACACIA CAVEN
Lodge Acacia Caven Un espacio de lleno de tranquilidad y confort ,conectado con la naturaleza, a 4 km del centro de de ciudad de Santa Cruz, ubicado en parcela de agrado privada. Casa de 100 metros cuadrados con Hot Tub externo, Terraza, Fogón, estacionamiento propio, zona para asado y entrada independiente.

Casa Sta. Cruz Valle-Colchagua Vineyard: Estc. BBQ Area
Casa Viñastay is located in the Colchagua Valley and on the wine route, 500 meters from the casino, the Colchagua Museum and the center of Santa Cruz. Ideal for teleworking with fast Wi-Fi, air conditioning, and a wood-burning stove. Firewood is available for its operation.

Casa de Campo in Santa Cruz
Modern country house very close to Santa Cruz. 4 bedrooms, master bedroom en suite. Master and second bedroom with a double bed. In the second bedroom, the bed can be separated into two singles. Many walks and sights along the wine route. 5 kilometers from the square.

House in Santa Cruz, O'Higgins Region, Chile
Property in Los Viñedos sector, Santa Cruz. Excellent location, minutes from downtown and with access to services. It has a large living-dining room with natural light, 2 bedrooms, 1 bathroom, service patio and parking. Quality construction and well equipped.
Popular amenities for Santa Cruz house rentals
House rentals with a pool

Dreamy country house

Country house to enjoy and have fun

Casa Santa Cruz, Colchagua Valley, Chomedague

Malva House, Palmilla, Santa Cruz

Country house in the heart of the city

Boutique House in Private Vineyard in Apalta

Casas Santa Cruz 1

Country House in Pichidegua
Weekly house rentals

Double room with twin beds and a private bathroom

Casa Trébol, your home away from home

“El Descanso” family plot

House in a natural setting

Furnished cabin

Casa El Huique

Gran Habitación Cama dos Plazas Baño in Suite

Cozy house in a great San Fernando location
Private house rentals

comfortable house, large garden with pool.

Casa F&B Nenquén

Casa Patronal - Yaquil Island, Santa Cruz

Country House in Colchagua · Pool · Cart

Lo Valdés - Casona

House with a view, Colchagua Valley, Lolol

House near the center with a view of the field

Spacious country house for families. San Vcte TT
When is the best time to visit Santa Cruz?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 228 | ﺩ.ﺇ 213 | ﺩ.ﺇ 231 | ﺩ.ﺇ 209 | ﺩ.ﺇ 202 | ﺩ.ﺇ 213 | ﺩ.ﺇ 209 | ﺩ.ﺇ 206 | ﺩ.ﺇ 198 | ﺩ.ﺇ 209 | ﺩ.ﺇ 213 | ﺩ.ﺇ 202 |
| Avg. temp | 22°C | 21°C | 19°C | 14°C | 11°C | 9°C | 8°C | 10°C | 12°C | 14°C | 18°C | 20°C |
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- Rentals with breakfast Santa Cruz
- Rentals with outdoor seating Santa Cruz
- Family-friendly rentals Santa Cruz
- Rentals with a fireplace Santa Cruz
- Smoking-friendly rentals Santa Cruz
- Pet-friendly rentals Santa Cruz
- Rentals with a patio Santa Cruz
- Rentals with a washer and dryer Santa Cruz
- Rentals with pools Santa Cruz
- Rentals with a fire pit Santa Cruz
- House rentals Colchagua
- House rentals O'Higgins
- House rentals Chile





