Vacation rentals in Panacea

4.88 out of 5 average rating, 269 reviews

Bungalow in Panacea

Otter lake cottage

The Otter Lake Cottage is in a small fishing village with beaches 6mi. It sets on 3/4 acre with a concrete grill area out back ,plenty of parking space if you want to bring your boat canoe or bikes. Large covered porch on the front. There is beautiful rivers for canoeing or swimming, great fishing it is also less than a mile away from the Gulf. Wakulla has great Seafood restaurant'syou can dine over the water or by it. We have a park for kids and the Gulf Marine lab where they can touch and learn about sea turtles and all marine life. This is the perfect place to have a quiet get away. Otter Lake is a great place to walk it has bald eagles bird trails walking trails a great place for picnics. It's located in the national forest just down the rd.

A serene beach scene is depicted, featuring smooth white sand dunes bordered by sparse green sea grass. Gentle waves lap against the shore under a clear blue sky, while a distant view reveals the coastline extending into the horizon.

4.95 out of 5 average rating, 59 reviews

The Refuge in Panacea

The Refuge has the St. Marks National Wildlife Refuge in its’ backyard to offer nature-watching from huge screened porches on lovely porch swings. Spend days enjoying all the area has to offer then return to share a bottle of wine and recount your adventures while counting the stars. Use the outdoor gas grill or the fully-equipped kitchen to cook up the areas amazing seafood. Stay in touch via the strong & reliable Wifi. We are *dog friendly*, please first read the policy & fees and bring Fido!

4.93 out of 5 average rating, 215 reviews

Barn in Panacea

Spend Summer Vacation @ Country Barn by the Coast

Experience Country Life, in a barn loft located in a wooded area close to the St Marks Refuge & the GOA. Its secluded & private, close to local beaches. View breataling sunsets. Great for family get a ways or R&R. Enjoy fishing, kayaking, biking & hiking, along the Ochlockonee Bay & Gulf. River flows to Carrabelle & Sopchoppy River. There is Fresh & Salt Water fishing. So bring the boat, bikes, kayaks, kids, pets, even grandma! Enjoy a fire & some star gazing. Make some family memories!

4.95 out of 5 average rating, 185 reviews

A shaded outdoor pavilion features wooden seating arrangements, including several Adirondack chairs and a round table. Potted ferns are placed on either side, adding greenery. A hot tub can be seen in the background, surrounded by natural landscaping.

Cabin in Tallahassee

Coastal City Cabin: A Cozy Florida Getaway A-Frame

Picture this.. Spend the day fishing out on the coast or swimming in the world's largest freshwater spring then some fun in town with great eats & live music! Finish the night with a hot tub soak under the stars. No worries, you can do it all again tomorrow! Conveniently nestled between Tallahassee and the 'Forgotten Coast', our cabin is a perfect match for your adventure-filled vacation. A quick 15 minute ride from the Tallahassee airport has you enjoying the sunset from our rocking chairs.

A tranquil scene at sunset features a wooden deck with a pair of turquoise adirondack chairs facing the serene Gulf of Mexico. The soft glow of the setting sun casts warm tones over the calm water and sandy shoreline, with gentle waves lapping at the beach.

4.98 out of 5 average rating, 104 reviews

Paradise Point! Direct Beachfront Florida Oasis!

Paradise Point is a Direct Beach front home perched on the shores of the Gulf of Mexico! This rare to find Beach House embodies relaxation and solitude. The white sand beach of Florida’s Forgotten coast is just out front. One of the most incredible locations for miles, the views and peacefulness are unrivaled. This is an elevated and updated Beach home with a Brand new appliance suite, custom granite counters & more updates. Wake to the sounds of waves on the beach just outside your door.

A serene beach scene displays soft pastel colors in the sky at sunset. Gentle waves lap the shore, where soft sand meets the water. Silhouettes of people can be seen walking along the water's edge, highlighting the expansive coastline.

5 out of 5 average rating, 210 reviews

Vintage Old Florida Charm “For The Birds”

Welcome to Natural Florida! Vintage 1938 cottage, 2 bedrooms/2 bathrooms, under ancient mossy oaks & palms in Panacea, FL. Comfortable, eccentrically decorated w/well-equipped kitchen. Near boat ramp, top seafood markets & wonderful restaurants. Close to public National & State Parks: St. Marks Wildlife Refuge & Lighthouse, AREA X, Wakulla Springs, Florida Birding & Hiking & Bicycle Trails, Dickerson & Levy Bay, Gulf of Mexico, Otter Lake, Mashes Sands Beach, Birdwatch, fish, & kayak.

A wooden rocking chair is positioned on the porch beside a small side table. The chair features a rustic finish, while green shutters frame the nearby window, enhancing the porch's inviting feel. Sunlight casts gentle shadows on the floor.

4.92 out of 5 average rating, 165 reviews

Fishermans Retreat

Fisherman's Retreat is the perfect location to get away from the stress of the city. Located in the heart of the quiet and cozy Panacea ocean community, you are close to several beaches, boat ramps, favorite local fishing spots, kids playground across the street and the Gulf Specimen Aquarium that is fun for all ages. Plus, you can take in and enjoy several local restaurants that will satisfy every culinary appetite. So, check out of the big city and check into our relaxing home.

4.91 out of 5 average rating, 94 reviews

A sheltered picnic area with a thatched roof is depicted, featuring a wooden table positioned to offer views of the tranquil water. Palm trees frame the scene, while rocks and grassy areas are visible along the waterfront.

Camper/RV in Panacea

Bayfront Retreat W/ Private Tiki Hut, Pool,Pickle

- Spacious 40 ft Glamper with king bed, recliners and 2 sleeper sofas - Dock - Resort Pool - pickle ball - keyless check in - on-site parking for up to 2 vehicles - picnic table with waterfront views - fully equipped kitchen - smart TV in living room - 10 min to bald point state park - 25 min to ochlockonee river state park -15 min to alligator point Beach - 6 min to Mashes sands Beach -5 min to Mashes sands boat ramp - convenient to multiple local restaurants

Superhost

A spacious screened-in patio features wooden flooring and walls with screening for ventilation. The entrance includes a ramp leading to the patio, with natural light streaming in. Surrounding greenery is visible through the screening, enhancing the feeling of openness.

Tiny home in Crawfordville

4.87 out of 5 average rating, 174 reviews

Spring Creek Getaway

Located in Spring Creek FL, a safe fish camp community on the gulf waters. This tiny house is the place to relax. Rocking chairs, fire pit, and sunsets all provided right here. Bring your boat and use the private boat ramp or launch the fishing kayaks provided. The house was decorated by my wife and deep cleaned by the both of us!! Relax in the Screened in patio and use the charcoal grill. Kayakers DREAM!! High End Sea Kayaks...wilderness tarpon 14

A scenic beach area is framed by tall pine trees on one side. Soft sand gently slopes down to the water's edge, where subtle waves wash ashore. A distant wooden pier extends into the water, completing the peaceful waterfront view.

4.98 out of 5 average rating, 81 reviews

Hideaway Beach Cottage

Take it easy at this Ochockonee bay-waterfront cottage getaway. Sits on a beautiful 1/2 acre wooded lot with old Florida charm. This home has been updated and has a very cozy interior. Do some fishing with 100ft of saltwater or just put your toes in the sand on your own beach in the backyard. Relax with those that matter the most. Boat ramp 5 mins away. There is room to park your boat or RV. Amazing sunsets and sunrises over the water is a must see.

Bungalow in Alligator Point

A serene beachfront scene is depicted, showcasing soft white sand and gentle waves lapping at the shore. Sunlight glimmers on the water's surface, while a few houses can be seen in the distance, surrounded by lush coastal vegetation.

4.96 out of 5 average rating, 119 reviews

Unplugged

Experience old Florida in this 1950's 1 bedroom 1 bathroom bungalow located on a tropical spit along the Forgotten Coast. Unplugged sits nestled in between the Gulf of Mexico and Alligator Harbor with beach on one side and a bay-side boat ramp on the other. The house sleeps two in the main bedroom, two on a sofa bed in the living area, and has a small bunk room off the porch that can accommodate two children. Sorry, we do not accept pets.

4.89 out of 5 average rating, 38 reviews

A serene beach landscape is presented, featuring soft white sand and calm waters under a clear blue sky. Silhouetted against the horizon, tall trees provide structure to the scene, while scattered rocks add texture along the shoreline.

Condo in Panacea

Bliss on the Bay

Ochlocknee Bay front condo located in George's Lighthouse gated community in beautiful Panacea, Florida. Enjoy beautiful sunset views from the patio, great fishing, biking and kayaking. Walk to community pool, tennis court and the famous Angelo’s Restaurant. Take a short scenic bike ride to Mashes Sands Beach or a short car ride to several Forgotten Coast beaches. St George Island is 1 Hour away. Bike/walking trails all around the area.

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Popular amenities for Panacea vacation rentals

Self check-in

Gym

BBQ grill

Laptop-friendly workspace

Wifi

Other great vacation rentals in Panacea

A vibrant sunset is captured over Ochlockonee Bay, showcasing soft pinks and oranges reflected on the water's surface. A long pier stretches into the bay, adding depth to the serene scene, framed by silhouetted structures along the shoreline.

5 out of 5 average rating, 14 reviews

Waterfront Ochlockonee Bay home, 2nd floor

A sandy path stretches through vegetation, leading toward the beach. The scene is framed by bushes and small trees, with a gentle transition from sand to the water beyond. The sky displays soft hues of orange, pink, and blue, indicating sunset.

5 out of 5 average rating, 26 reviews

Face in the Wind

5 out of 5 average rating, 3 reviews

Relax & Refresh: Waterfront Cottage in Panacea

A panoramic view of a serene river at sunset, displaying calm waters that reflect the sky's soft hues. A wooden dock is visible on the right, extending over the water, while clouds drift lazily above, creating a tranquil atmosphere.

4.98 out of 5 average rating, 65 reviews

River of Dreams

5 out of 5 average rating, 10 reviews

Home in Carrabelle

Historic Driftwood Cottage Waterfront - Pets OK

5 out of 5 average rating, 54 reviews

A serene beach scene is visible, featuring gentle waves lapping at the shore. Several seagulls can be seen walking along the wet sand, with the calm blue ocean stretching into the distance under a clear sky.

Home in Alligator Point

Breathtaking sunsets at Gulf Coast Breeze

Guesthouse in Crawfordville

An aerial view captures a coastal community bordered by blue waters and green landscapes. Homes line the shores, surrounded by waterways and lush vegetation. The sky above is bright with scattered clouds, enhancing the serene atmosphere of the scene.

5 out of 5 average rating, 38 reviews

Bungalow with a water view from every window

The exterior of a single-story home is presented, featuring a bright blue front door framed by two tall windows with decorative shutters. Lush green plants and landscaping enhance the entryway, and a small porch is highlighted, creating an inviting first impression.