Vacation rentals in Panacea

4.88 out of 5 average rating, 276 reviews

The living area is furnished with a large, inviting couch and features artwork on the walls, including nautical-themed pieces. A lamp beside the couch provides ambient lighting. A decorative arrangement with a wine bottle and glasses sits on a white countertop, which divides the space.

Bungalow in Panacea

Otter lake cottage

The Otter Lake Cottage is in a small fishing village with beaches 6mi. It sets on 3/4 acre with a concrete grill area out back ,plenty of parking space if you want to bring your boat canoe or bikes. Large covered porch on the front. There is beautiful rivers for canoeing or swimming, great fishing it is also less than a mile away from the Gulf. Wakulla has great Seafood restaurant'syou can dine over the water or by it. We have a park for kids and the Gulf Marine lab where they can touch and learn about sea turtles and all marine life. This is the perfect place to have a quiet get away. Otter Lake is a great place to walk it has bald eagles bird trails walking trails a great place for picnics. It's located in the national forest just down the rd.

Bungalow in Alligator Point

A wooden staircase leads down to a sandy beach, framed by low vegetation. The clear blue sky reflects on the calm ocean waters, creating a serene coastal view. Distant clouds add subtle texture to the expansive sky, while the horizon blends seamlessly with the sea.

4.99 out of 5 average rating, 108 reviews

☀Fun Flamingo: Beachfront/Quiet Retreat/Best Views

The Fun Flamingo is a charming 1950’s ranch bungalow directly on the beach of Alligator Point; part of Old Florida's Forgotten Coast. A great getaway for enjoying the ocean and its habitat. The 11-window ocean-facing sunroom has amazing views and is a great place to watch dolphins play just off-shore. Or just a few steps outside the back and you're enjoying the endless beaches of Alligator Point. 2 bedrooms, a bunkroom & 2 baths. 8 guests limit. And while a pet is allowed, there is $120 fee.

4.86 out of 5 average rating, 213 reviews

A small, single-story home is situated on a grassy area, featuring a light-colored exterior and a green metal roof. A white picket fence borders the property, with a screened porch visible at the front. Tall trees provide a natural backdrop behind the house.

Tiny home in Carrabelle

The Sweet Peach - 2 Adults 1 toddler

This NOT so tiny, tiny home is located across from the bay, has everything needed to enjoy your vacation. Completely remodeled in 2017. Shabby chic, beach decor, Q sized bed, 2 stuffed chairs & complete kitchen. Screened in porch, dining area, chairs. Relax with a beverage & enjoy the amazing view of the bay. Affordable small family (2 adults 1 small child) vacation or romantic getaway. Professionally cleaned after each guest stay. Bathroom is small with corner shower. Pet policy in listing

Apartment in Lanark Village

An outdoor patio features a combination of wood and tiled flooring, with two white chairs positioned beside a small table. A stone birdbath sits at the center, while string lights are draped above for a subtle ambiance. A door leads into the interior space.

4.81 out of 5 average rating, 214 reviews

Scottie's House

Casa del Scottie is a charming updated apartment, once home to an officer during WWII. The community, then called Camp Gordon Johnston, was set near the beautiful beaches of the gulf coast, and St George Island, for easy access during training for the D-Day invasion! It is situated conveniently between the fresh, upscale town of Appalachacola, and the scenic state parks of Wakula Springs. Lanark is a beautiful place to stay to explore the history and breathtaking beaches of the Forgotten Coast!

4.94 out of 5 average rating, 219 reviews

Three horses graze peacefully in a lush green field, surrounded by a wooden fence. A spacious barn with a light-colored exterior and green roof stands in the background, framed by tall trees offering a serene, natural setting.

Barn in Panacea

Spend Summer Vacation @ Country Barn by the Coast

Experience Country Life, in a barn loft located in a wooded area close to the St Marks Refuge & the GOA. Its secluded & private, close to local beaches. View breataling sunsets. Great for family get a ways or R&R. Enjoy fishing, kayaking, biking & hiking, along the Ochlockonee Bay & Gulf. River flows to Carrabelle & Sopchoppy River. There is Fresh & Salt Water fishing. So bring the boat, bikes, kayaks, kids, pets, even grandma! Enjoy a fire & some star gazing. Make some family memories!

4.95 out of 5 average rating, 190 reviews

The A-Frame cabin is framed by lush greenery, featuring a welcoming front porch with a decorative railing and an American flag. Steps lead up to the entrance, while large windows enhance natural light, creating an inviting appearance amidst the serene landscape.

Cabin in Tallahassee

Coastal City Cabin: A Cozy Florida Getaway A-Frame

Picture this.. Spend the day fishing out on the coast or swimming in the world's largest freshwater spring then some fun in town with great eats & live music! Finish the night with a hot tub soak under the stars. No worries, you can do it all again tomorrow! Conveniently nestled between Tallahassee and the 'Forgotten Coast', our cabin is a perfect match for your adventure-filled vacation. A quick 15 minute ride from the Tallahassee airport has you enjoying the sunset from our rocking chairs.

A charming elevated beach house is surrounded by sandy terrain and swaying palm trees. A wooden deck with blue and yellow chairs provides a relaxing spot to enjoy the sun, while a hammock hangs nearby for added comfort. Steps lead up to a spacious covered porch.

4.98 out of 5 average rating, 109 reviews

Paradise Point! Direct Beachfront Florida Oasis!

Paradise Point is a Direct Beach front home perched on the shores of the Gulf of Mexico! This rare to find Beach House embodies relaxation and solitude. The white sand beach of Florida’s Forgotten coast is just out front. One of the most incredible locations for miles, the views and peacefulness are unrivaled. This is an elevated and updated Beach home with a Brand new appliance suite, custom granite counters & more updates. Wake to the sounds of waves on the beach just outside your door.

5 out of 5 average rating, 213 reviews

The living area features a floral-patterned yellow couch complemented by two armchairs with a rattan design. A round side table sits beside the couch, and a large area rug with a geometric pattern covers the wooden floor. Natural light is filtered through sheer curtains.

Cottage in Panacea

Vintage Old Florida Charm “For The Birds”

Welcome to Natural Florida! Vintage 1938 cottage, 2 bedrooms/2 bathrooms, under ancient mossy oaks & palms in Panacea, FL. Comfortable, eccentrically decorated w/well-equipped kitchen. Near boat ramp, top seafood markets & wonderful restaurants. Close to public National & State Parks: St. Marks Wildlife Refuge & Lighthouse, AREA X, Wakulla Springs, Florida Birding & Hiking & Bicycle Trails, Dickerson & Levy Bay, Gulf of Mexico, Otter Lake, Mashes Sands Beach, Birdwatch, fish, & kayak.

A single-story home features a welcoming front porch with green railings and a decorative entrance. A light color palette of the exterior is complemented by green shutters, and tall palm plants line the front yard, creating an inviting outdoor space surrounded by natural landscaping.

4.91 out of 5 average rating, 176 reviews

Fishermans Retreat

Fisherman's Retreat is the perfect location to get away from the stress of the city. Located in the heart of the quiet and cozy Panacea ocean community, you are close to several beaches, boat ramps, favorite local fishing spots, kids playground across the street and the Gulf Specimen Aquarium that is fun for all ages. Plus, you can take in and enjoy several local restaurants that will satisfy every culinary appetite. So, check out of the big city and check into our relaxing home.

4.9 out of 5 average rating, 124 reviews

A luxury travel trailer is highlighted under soft evening lights, nestled beneath a spacious covered porch. Two cozy outdoor chairs surround a fire pit, integrating relaxation and comfort within a serene outdoor setting.

Camper/RV in Carrabelle

Gone Coastal Luxury Glamper by the Beach

This coastal paradise is a luxury travel trailer located in the small town of Carrabelle, FL on the Forgotten Coast known for fishing, boating, golfing and relaxing. Whether you’re staying for the weekend or relaxing for a month-long getaway, this is the perfect place for you. With restraunts, live music, public boat ramps for fishing and boating to Dog Island and St. George Island, charter fishing, air boat rides, War Museums, lighthouse tours & beautiful white sandy beaches.

4.87 out of 5 average rating, 129 reviews

A serene sunset is captured over calm waters, with soft hues of orange and pink reflecting on the surface. Silhouettes of palm trees are visible in the foreground, enhancing the tranquil coastal setting.

Condo in Carrabelle

St. James Sanctuary

This lovely condo on Florida's "Forgotten Coast" provides guest with a beautiful view and tranquility only seen in this area of Florida. Located in St. James in Franklin county, you are 44 miles from the Tallahassee airport, it is convenient to a big city, while set in a quiet, rural beach area. You are only minutes from St. James Golf club, Carrabelle (7 miles away with public beach), St. George Island, Panacea and Apalachicola. Swimming not recommended (more like a bay).

Tiny home in Crawfordville

A view features two wooden tiny houses bathed in golden sunset light. Rocking chairs are positioned on gravel ground, facing a fire pit, with palm trees framing the scene. The open space beyond offers a glimpse of the water, enhancing the tranquil atmosphere.

4.88 out of 5 average rating, 177 reviews

Spring Creek Getaway

Located in Spring Creek FL, a safe fish camp community on the gulf waters. This tiny house is the place to relax. Rocking chairs, fire pit, and sunsets all provided right here. Bring your boat and use the private boat ramp or launch the fishing kayaks provided. The house was decorated by my wife and deep cleaned by the both of us!! Relax in the Screened in patio and use the charcoal grill. Kayakers DREAM!! High End Sea Kayaks...wilderness tarpon 14

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Popular amenities for Panacea vacation rentals

Beachfront

Gym

BBQ grill

Laptop-friendly workspace

Wifi

Panacea beach vacation rentals

A wooden boardwalk leads to a charming oceanfront beach home, surrounded by natural greenery. The two-story structure features a covered upper deck with lounge seating and an umbrella. The ground level offers additional shaded outdoor space under the house.

4.97 out of 5 average rating, 157 reviews

Direct Ocean Front No Hurricane Damage PetsWelcome

4.98 out of 5 average rating, 46 reviews

A serene beach scene captures the tranquil coastline illuminated by a warm sunset. The gentle waves reflect the orange and yellow hues of the sky. A lone tree stands along the edge, adding a touch of nature to the peaceful atmosphere.

Cottage in Panacea

Seaglass-on St. Teresa Beach

A wooden deck provides a clear view of a sandy pathway leading to the beachfront. Tall pine trees frame the scene, contrasting with the blue sky and gentle waves in the distance. The natural landscape features coastal grasses, enhancing the sense of tranquility.

5 out of 5 average rating, 35 reviews

Tucked Away Private Beachfront Home

An aerial view captures the attractive Bayfront property surrounded by lush trees, with the ocean visible in the background. A driveway is shown leading to the home, accented by landscaped stones and greenery. The American flag gently flutters in the breeze.

4.93 out of 5 average rating, 15 reviews

New Waterfront Property/Boat Dock/Dogs Allowed

4.96 out of 5 average rating, 72 reviews

Direct beachfront private luxury villa Sea La Vie

4.89 out of 5 average rating, 104 reviews

A sandy pathway leads from the grassy shore to the calm waters of the bay. The horizon stretches out under a clear blue sky, with gentle waves lapping at the beach. The lush grass adds a natural touch to the beach area.

Cottage in Sopchoppy

Comfy cottage on private beach

A serene beach scene presents gentle waves lapping at the sandy shore. The sky is painted with soft hues of pink and purple as twilight approaches, reflecting calming colors on the water's surface. The tranquil setting invites relaxation and contemplation.

4.96 out of 5 average rating, 54 reviews

Private Gulf Getaway Ground Level Beach House

4.98 out of 5 average rating, 109 reviews

A quaint entryway features a covered patio with a patterned brick floor. A wooden trellis is adorned with greenery overhead. Two chairs are positioned on either side, with a small decorative table near the entrance, offering a welcoming atmosphere to the cottage.

Guesthouse in Carrabelle

Private Cottage in an Enchanted Garden-by-the-Sea

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Panacea house rentals

The exterior of a cheerful yellow cottage features a covered porch with wooden railings and concrete paths. Lush greenery surrounds the entrance, and decorative elements can be seen on the porch. The inviting entrance door is centrally located, welcoming guests.

4.99 out of 5 average rating, 75 reviews

Oyster Cottage (Wheelchair Friendly)

A raised coastal home with a wrap-around deck stands amidst sandy terrain. Palm trees provide a natural backdrop, and the ocean is visible nearby. The open space beneath the home accommodates parking and outdoor activities, showcasing a relaxed beach lifestyle.

5 out of 5 average rating, 26 reviews

Nirvana Beachfront Home

4.89 out of 5 average rating, 63 reviews

The cottage exterior features a shaded porch with two chairs and a vibrant blue door. A small area of outdoor flooring provides space for relaxation, while lush greenery surrounds the home, creating a serene and inviting entryway.

Home in Lanark Village

The Lazy Lizard a cozy cottage hideaway

A spacious gathering area is featured, enclosed by screens and designed with wooden flooring. A ceiling fan hangs above, and colorful beach towels are neatly folded on benches. Access to the outdoors is provided through a door, offering views of the surrounding greenery.

4.81 out of 5 average rating, 88 reviews

"Dune Your Thing" - 3br/2ba - Fisherman's Paradise

A private dock is positioned over calm water, surrounded by lush greenery and trees. Reflections of the trees are visible in the clear water, creating a serene atmosphere. An adirondack chair is placed on the wooden deck, inviting relaxation and enjoyment of the natural surroundings.

4.98 out of 5 average rating, 145 reviews

Wakulla River House - Watch the Manatees Swim By

4.97 out of 5 average rating, 236 reviews

A charming single-story home is presented with light-colored siding and blue shutters, framed by well-maintained hedges. The front porch features a welcoming entry door and a potted plant, set against a backdrop of green lawn and mature trees.

Home in Saint Marks

Little Piece of Paradise/No stairs/Bike/Boat/Bird

A serene lakeside view is presented during sunset, showcasing silhouettes of trees with Spanish moss. The gently rippling water reflects warm hues of orange and pink, while a peaceful outdoor seating area is visible, inviting relaxation and connection with nature.

4.89 out of 5 average rating, 35 reviews

S + W's Guest House 2

A wooden boardwalk leads to a sandy beach framed by two palm trees. The bright sun illuminates the scene, highlighting the wide expanse of sand and the calm ocean in the distance. The clear blue sky enhances the tranquil beach atmosphere.

4.92 out of 5 average rating, 12 reviews

Peaceful Beach Front Retreat

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Lakefront house rentals in Panacea

A newly constructed home features a welcoming front entrance with wooden steps leading to the porch. Surrounded by a manicured lawn, palm trees and a gravel driveway enhance the contemporary design. The bright blue sky showcases scattered clouds, contributing to a serene outdoor environment.

5 out of 5 average rating, 10 reviews

Trifecta

4.93 out of 5 average rating, 14 reviews

An outdoor dining area is set under a large umbrella, featuring a wooden table surrounded by six black chairs. Potted flowers add a touch of color, with a scenic lake view visible in the background. Natural wood accents create a warm atmosphere.

Home in Tallahassee

Sunset Memories - fishing dock, pool table

A shaded deck features a single rocking chair facing a serene pond, surrounded by lush greenery. The inviting space offers a peaceful view of the water and natural landscape, providing an ideal setting for relaxation and reflection.

5 out of 5 average rating, 13 reviews

Refuge on the Water

A wooden deck features a small table and two folding chairs, surrounded by a lush green landscape. A hammock hangs nearby, providing a relaxing spot to enjoy the views of the bayou, while soft string lights add a warm glow during evening hours.

5 out of 5 average rating, 85 reviews

Hooked on the Bayou, Waterfront, Fish, Scenic,

A living area features a large leather sofa adorned with decorative pillows. A low table stands in front, complemented by a textured blue area rug. Expansive windows provide natural light and views of the outdoor area with lush greenery.

5 out of 5 average rating, 46 reviews

Relaxing River front home near Gulf with dock

The spacious living area features high wooden beams and large windows, allowing natural light to fill the room. A comfortable blue sectional sofa is positioned around a coffee table with a spiral staircase leading to an upper level. A dining area with yellow chairs is partially visible in the background.

5 out of 5 average rating, 4 reviews

Luxury Retreat | Private Spring | Nature Sanctuary

A beachfront home stands amidst tall trees, featuring a sandy area leading to the water's edge. Several lounge chairs are arranged on the beach, inviting relaxation, while the house’s elevated structure provides ample space beneath for enjoyable gatherings.

4.93 out of 5 average rating, 100 reviews

The Bella Beach Treehouse: New Pool. Kayak. Golf