Guesthouse vacation rentals in Mesa

Find and book unique guesthouse rentals on Airbnb

Quick stats about guesthouse rentals in Mesa

Total vacation rentals
Explore 160 vacation rentals in Mesa
Nightly prices starting at
Mesa vacation rentals start at ﺩ.ﺇ 110 per night before taxes and fees
Verified guest reviews
Over 14,330 verified reviews to help you choose
Family-friendly vacation rentals
30 properties offer extra space & kid-friendly amenities
Pet-friendly vacation rentals
Find 40 rentals that welcome pets
Vacation rentals with a pool
50 properties feature pools
Rentals with dedicated workspaces
80 properties have a dedicated workspace
Wi-Fi availability
160 of Mesa vacation rentals include wi-fi access
Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mesa rentals
4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!
Nearby attractions
Mesa's top spots, include Golfland Sunsplash, Sloan Park, and Hohokam Stadium

Top-rated guesthouse rentals in Mesa

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

A spacious California King bed is centered in the room, adorned with a white quilt. Two pillows rest against the headboard. Natural light filters through a window with blinds, illuminating the inviting sleeping area.

Guesthouse in Gilbert

Spacious Casita, Quiet, Peaceful Home - No Stairs!

Cozy Casita in a beautiful, quiet neighborhood. California King bed sleeps two comfortably. 50 inch TV has cable, Netflix, DVD player with assortment of movies. Keurig coffee pot, fridge and microwave. Dining table inside. Outdoor seating opens to peaceful, scenic backyard. Parking available in the driveway. Park to the left of 2 car garage. Our Casita is a modest room that we have done our best to make comfortable for travelers who want an alternative to an impersonal hotel. No pets allowed.

4.94 out of 5 average rating, 504 reviews

Top guest favorite

Guesthouse in Mesa

Entire Suite: Private and Cozy Clark House Casita

Come and enjoy your stay at our unique and cozy casita in Clark historic neighborhood of downtown Mesa! Catch up on your favorite shows in the living room with our 65 inch HD smart TV, or watch a movie while cozied up on our comfy queen size bed using the second tv in the bedroom. Our space has a kitchenette to prepare meals, and a full size bathroom. You may also relax in the shaded patio surrounded by mature trees and lush greenery. No smoking or vaping inside or outside of the property.

4.97 out of 5 average rating, 208 reviews

Top guest favorite

A private room features a spacious bed with layered bedding, complemented by two decorative pillows. A small dining table with two chairs sits in the corner. Large windows with wooden shutters frame a view of greenery outside, and landscape artwork adorns the wall.

Guesthouse in Chandler

Cozy Casita with kitchenette

Bright, comfortable, private room with queen bed, TV, internet, A/C, bath & kitchenette (electric skillet, refrig/freezer, microwave, toaster, Cuisinart coffee maker (single cup or pot), water filter, sink). Add herbs from our courtyard to your stir-fry. Separate casita is located in a small, quiet community near freeways (101, 202). Restaurants & entertainment options nearby in Chandler or Gilbert. Drug store, grocery and fast food all within walking distance (half mile). Community pool.

4.98 out of 5 average rating, 127 reviews

Guest favorite

A cozy studio space is showcased with a king-size bed framed by bedside tables and lamps. A modern ceiling fan offers comfort overhead. A large flat-screen TV is mounted on the wall opposite the bed, with a console below for added storage. The flooring is finished in warm tones.

Guesthouse in Mesa

The Mesa Casita

The casita was just finished being completely renovated with brand new flooring, paint, appliances, kitchen cabinets, walk-in closet, bathroom, brand new BEDAGA king-size mattress, furnishings, whisper-quiet air conditioner, LED lighting, smooth stucco, and brand new fixtures (updated in January 2021). In addition, the casita has its own washer/dryer for your use only so you can travel light. CableTV, lightning fast WiFi, Amazon FireStick with Netflix are all provided at no extra charge.

4.9 out of 5 average rating, 124 reviews

Top guest favorite

The studio apartment interior features a full kitchenette with modern appliances, including a microwave and refrigerator. A round table with two chairs is positioned beside a vibrant yellow door, while potted plants and decorative items are displayed on the shelves, adding a touch of greenery.

Guesthouse in East Mesa

Prickly Pear Hideout -Golf Course Studio Apartment

🌵 Prickly Pear Hideout – Your cozy desert escape! This private studio apartment sits on Golden Hills Golf Course and has a park & duck pond nearby. ⛳️🏌️ Perfect for golfers, couples, and solo travelers looking for a relaxing stay. Quiet, stylish, and less than 5 minutes away from restaurants and Superstition Springs mall. 🛍️ About 20 minutes from the Mesa Gateway airport and Downtown Mesa, and 40 minutes from the Phoenix Sky Harbor airport. ✈️ Book now for the perfect getaway!🌵🏜️

4.92 out of 5 average rating, 95 reviews

Top guest favorite

Guesthouse in Chandler

Historic Firehouse Downtown Chandler Large shower

Welcome to the historic Firehouse, where you're a quick 5-minute stroll away from bustling Downtown Chandlers top-notch restaurants and bars. You're staying in a historic building that has been magically transformed into a cozy Airbnb retreat. Step Inside the Firehouse Garden with 2 stylish bedrooms that are ready to whisk you away into dreamland, 1 amazing bathroom. With enough space to accommodate up to 6 guests. This is the perfect spot for a getaway with your favorite people.

4.92 out of 5 average rating, 200 reviews

Top guest favorite

A bright and airy studio space features a comfortable bed with crisp white bedding and a cozy sitting area with a plush sofa. Natural light fills the room through the window, and a small bedside table with a lamp adds a touch of warmth.

Guesthouse in Mesa

Private, Convenient Studio Apartment

Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

4.98 out of 5 average rating, 315 reviews

Top guest favorite

The entrance of the casita features a modern design with a stone column supporting the overhang. A walkway leads to a contemporary front door, framed by landscaped greenery and yellow flowers, creating an inviting entryway.

Guesthouse in Chandler

Chandler Estates

Come enjoy and relax in our cozy casita situated on an acre. It is 750sf with a full kitchen, family room, full bathroom with a walk-in shower, laundry, and its own exterior patio with dining, chairs and BBQ. Only minutes to downtown Chandler with a lively restaurant/bar and shopping area. If you love the outdoors enjoy the multiple golf courses, hiking, and biking trails all just a few a miles away. Airport is a short 20 minute drive with easy access to multiple freeways.

4.99 out of 5 average rating, 115 reviews

Top guest favorite

Guesthouse in Gilbert

Private and Quiet - 1 bdrm/1 bath Casita

**we are also open to longer term renters, send me a message for more info** Fully furnished 1 bed/1 bath casita w/ queen size bed. Living room can sleep more as the sofa and loveseat both fully recline (see photos). Front door is keyless entry for self check-in. Enjoy access to the shared front courtyard, parks with kids play areas and tennis courts (all walking distance). Great for couples or business travelers. Close to shopping, dining & easy freeway access.

4.86 out of 5 average rating, 278 reviews

Top guest favorite

A well-lit bedroom features a king size bed adorned with a floral blue and white duvet. Natural light streams in through plantation shutters. A minimalist armchair and lamp complement the space, while a simple rug adds warmth underfoot.

Guesthouse in East Mesa

Mesa Casita with King Bed

Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

4.96 out of 5 average rating, 575 reviews

Guest favorite

Guesthouse in East Mesa

Orchard Cottage, Heated Pool and Hot Tub

Beautiful private self contained suite with a large heated pool and hot tub. Very private and far away from other living areas. Great fast internet, AC is new and works great (important in Arizona) and the bathroom shower is amazing. Lots of beautiful sitting spaces, sun or shade, relax at the pool or just hang out and read on the large hammocks.

4.9 out of 5 average rating, 246 reviews

Top guest favorite

A welcoming guest house is presented with a blend of white siding and natural stone accents, framed by lush greenery. A pathway leads to the entrance, flanked by well-maintained gardens. An American flag is displayed, contributing to the property’s inviting exterior.

Guesthouse in Mesa

The White Barn @ Freedom Farms

Kick off your boots and relax in this calm, stylish, private guest house on Freedom Farms! Explore the natural swimming pond on the property, venture out to the Sonoran desert for a nature hike, tube down the salt river or mountain bike in Usery! You'll find our location close to the city but not in the city.

4.95 out of 5 average rating, 182 reviews