House vacation rentals in Mesa County

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Top-rated house rentals in Mesa County

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Guest favorite
A private hot tub is illuminated with soft blue light, positioned under a shelter. A cozy seating area features comfortable chairs adjacent to a fire pit, with warm flames flickering. Twinkling string lights provide a welcoming ambiance against the night sky.
Home in Palisade
4.93 out of 5 average rating, 289 reviews

Peach Pad! hot or cool tub 2 bedrooms 2 bathrooms

Sandstone views, outdoor area with private hot tub, can be kept cool in hot weather just message your preference. Bedrooms with en-suite bathrooms and are situated on opposite sides of the home for privacy. 7-10 minute bike ride to downtown, 5-10 minute walk to three vineyards,. Orchard surrounds 900 sq ft bedrooms and the living room have smart TVs, the kitchen is well equipped. The fenced yard has shaded outdoor areas to BBQ and enjoy sunsets. Best for 4 guests comfortable roll away bed for 5.

Top guest favorite
A hot tub is situated on a patio area, surrounded by a white fence. Two hanging egg chairs provide cozy seating. Soft landscape lighting reflects off the water, with a twilight sky featuring distant clouds and a colorful sunset in the background.
Home in Grand Junction
4.91 out of 5 average rating, 184 reviews

420Friendly_HotTub_12kGameArcade_WineBar_5Bed

✨This is 420 Friendly home and you are welcome to smoke and use any marijuana products you would like in the comfort of the house. (no tobacco) I provide smoking accessories that are clean and sanitized after each guest and kept safe in a kitchen cabinet out of reach of kids. Dogs are welcome with a $50 fee. ⭐Multiple Wineries ➡15 min drive ⭐Mesa University ➡5 min drive ⭐Airport➡ 5 min drive ⭐Downtown GrandJunction ➡8 min drive ⭐Amtrak Train Station➡10 min drive ⭐Palisade Orchards ➡15 min d

Top guest favorite
A spacious log cabin features a charming facade with wooden shutters adorned by flower boxes. The surrounding landscape showcases rolling hills and a bright blue sky with scattered clouds, enhancing the rustic and inviting appearance of the home.
Home in Palisade
4.98 out of 5 average rating, 119 reviews

Peach Chalet, views, quiet, 5 min to downtown

No chores here, you're on vacation! Located just 4 miles from Palisade Rim Trailhead, home of the Palisade Plunge. The Peach Chalet is all yours, with plenty of room for your bikes! Privacy and views, plenty of room to relax indoors & out! Talbott's Cider House is a quarter-mile away, and downtown Palisade is 1.5 miles away. World-class wineries surround you! The Chalet is 2 bedrooms and 1 bath on main floor, loft and 2nd bath upstairs. Fully-stocked kitchen. Join us for your relaxing getaway!

Guest favorite
A welcoming entrance features wooden steps leading to a front door framed by greenery. The façade is complemented by natural stone accents and surrounded by lush grass and aspen trees, creating an inviting connection to the outdoors.
Home in Mesa
4.91 out of 5 average rating, 122 reviews

Powderhorn Grand Mesa Classy Family Cabin

Enjoy the outdoor recreation paradise of Powderhorn and the Grand Mesa from your spacious, cozy home. Winter brings downhill and cross-country skiing, snowshoeing, ice fishing and beautiful snowy vistas. Summer allows hiking and all things outdoors sounded by million acres of public lands. The 800 square mile top of the Grand Mesa hosts 300 lakes for fishing as well as paddle boarding and other small watercraft. Hiking trails galore and Powerhorn mountain supports summer mountain biking.

Guest favorite
Home in Palisade
4.92 out of 5 average rating, 239 reviews

The Pali House - 10 Acres & Wine Country Views

Welcome to The Pali House, a recently renovated 2-bed, 2-bath retreat on 10 private acres in Palisade wine country. Panoramic views, wrap-around porch, king bed, and the best stargazing in Colorado. Five minutes to wineries and dining, 40 minutes to Powderhorn. Designed for travelers seeking space, privacy, and stunning Western Slope sunsets. The home is extra large for groups of 4 and is fully stoked with everything you need to make Palisade home for a trip away. Your hosts, Joe & Trish

Top guest favorite
A spacious porch features wooden flooring and is lined with tranquil seating options, including a set of chairs and a swing. Natural light filters through the surrounding trees, enhancing the peaceful outdoor space.
Home in Delta County
4.96 out of 5 average rating, 291 reviews

2 Bedroom Ranch House

Just a mile off of Highway 65 sits Tongue Creek Ranch. The Ranch is located in the fertile valley junction of Tongue Creek & Surface Creek. Enjoy your own private 2 bed 1 bath ranch house. Both bedrooms have a super comfy pillow top queen size bed. WIFI is a fast 1gig fiber optic line. Enjoy a full kitchen, washer and dryer, and a sofa in the family room. The front patio is always in the shade. Ask about the optional cabin on site for use as a private detached room for overflow family.

Top guest favorite
A contemporary home is presented with a wooden exterior, surrounded by a gravel area. Large glass doors offer views into the interior space. Two outdoor chairs are positioned on the patio, with wildflowers and vegetation framing the scene.
Home in Loma
5 out of 5 average rating, 670 reviews

Fruita/Loma Guest House at the Perfect Day Getaway

This newly constructed "Green" home is a mix of modern and country styles and will surely inspire you to enjoy all of the outdoor activities the Grand Valley has to offer. The Perfect Day Getaway house is located on a quaint farm within 8 minutes of world-class hiking, mountain and road bicycling, and river rafting. It is a great launching point for day trips to Moab and the Grand Mesa as well! It was built to maximize the southern exposure and views of the Colorado National Monument.

Top guest favorite
A wooden pergola with a dining table and chairs is situated in a garden area, framed by lush greenery. A yellow building and a red barn with a green roof are visible in the background, set against a colorful sunrise sky.
Home in Palisade
4.97 out of 5 average rating, 287 reviews

Galloway Ranch Palisade Colorado

Recent review: The best place we've ever stayed at, hands down! The location felt like a dead end road, yet close to everything. The yard had beautiful flower beds, not to mention the amazing view of Mt. Garfield! The house itself was very comfortable and had anything you can imagine in the kitchen, making a few at home dinners a breeze. Owners Note: One (1) dog 45 lbs max allowed unless an additional dog is approved in advance, please include # of people and # of dogs when booking.

Top guest favorite
A two-story wooden house is positioned in an open area, surrounded by a fence. The front porch features a railing and is accessible by a stone walkway. A backdrop of rolling hills and mountains under a blue sky is visible, enhancing the outdoor setting.
Home in Collbran
4.99 out of 5 average rating, 100 reviews

Mountain Ranch Retreat

Enjoy the beautiful Plateau Valley views from this house. This is a great launching pad for a Western Colorado adventure. Located Just 30 minutes from Vega State Park. 35 minutes from Powderhorn Ski Area. 15 minutes from the Grand Mesa. And just 45 minutes from Palisade. It is also in the center of Colorado hunting unit 421. Two bedrooms upstairs and one bathroom downstairs. Sleeps up to 6. Fully furnished kitchen for your use. all you need to bring are the groceries.

Top guest favorite
A modern house is set against a clear night sky filled with stars. The exterior features large glass doors, providing a seamless view of the surroundings. A spacious patio area is visible, bordered by natural landscaping, creating a sense of tranquility and connection to nature.
Home in Palisade
4.98 out of 5 average rating, 163 reviews

Rapid Creek Retreat

High above the town of Palisade, nestled in the foothills of the Grand Mesa, is the Rapid Creek Retreat. Surrounded by untouched public land you will experience the true gift and grit of Colorado. Enjoy views of the big sky from sunrise to sunset and beyond for magical star gazing. We planned for this home to be ours, every detail of this home was built with intent and love. The feeling here is truly special. For those ‘rough around the edges. Sincerely, The Busch’s

Top guest favorite
A two-story house is seen from the outdoor area, featuring a patio with several chairs and tables. A gravel driveway leads to lush vineyards in the background, framed by distant mountains under a clear blue sky.
Home in Palisade
5 out of 5 average rating, 133 reviews

Love Orchard

You will enjoy breathtaking endless views of orchards, vineyards and the Bookcliff mountains and amazing sunsets from the bright, open great room and balcony. You may think you are in the clouds! The peace and quiet you will feel in this lovely new home will surely refresh you. Located on the fruit and wine byway, there are 6 wineries within 3 miles yet you are only 2.5 miles from downtown Palisade and its plentiful offerings. This home is calling your name!

Top guest favorite
An expansive view of the West Elks mountain range is visible from the front porch. A wooden railing frames the scene, while a fire pit area is situated on the ground below. Lush fields and rolling hills stretch toward the mountains under a clear blue sky.
Home in Crawford
4.98 out of 5 average rating, 114 reviews

Needle Rock View Retreat

Feast your eyes on this awesome and unobstructed view of the West Elks mountain range and Grand Mesa from our big front porch! The house features 3 bedrooms, 2 bathrooms, living room with sleeper sofa, kitchen, dining area, and a second living area downstairs. Outside you’ll find a patio with fire pit where you can sit around a campfire and enjoy the incredible view of Needle Rock and surrounding mountains. We also offer an RV site with full hookup.

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