House vacation rentals in Mesa County

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Top-rated house rentals in Mesa County

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Guest favorite
A private hot tub is illuminated with soft blue light, positioned under a shelter. A cozy seating area features comfortable chairs adjacent to a fire pit, with warm flames flickering. Twinkling string lights provide a welcoming ambiance against the night sky.
Home in Palisade
4.92 out of 5 average rating, 278 reviews

Peach Pad! hot or cool tub 2 bedrooms 2 bathrooms

Sandstone views, outdoor area with private hot tub, can be kept cool in hot weather just message your preference. Bedrooms with en-suite bathrooms and are situated on opposite sides of the home for privacy. 7-10 minute bike ride to downtown, 5-10 minute walk to three vineyards,. Orchard surrounds 900 sq ft bedrooms and the living room have smart TVs, the kitchen is well equipped. The fenced yard has shaded outdoor areas to BBQ and enjoy sunsets. Best for 4 guests comfortable roll away bed for 5.

Top guest favorite
A rustic carport features a vintage vehicle with weathered paint, under a metal roof. An American flag hangs from one post, while colorful hanging planters add a touch of greenery. The surrounding open area is dotted with sparse grass and low shrubs.
Home in Orchard City
4.95 out of 5 average rating, 586 reviews

The Orchard House

**A devastating freeze in October 2020 killed all 400 of our sweet cherry trees and many of our peach trees. Sadly, our orchard is not the lush green jewel it once was. We are planting new cherry trees in the Spring of 2022. While the orchard views have changed, the Orchard House continues to offer a very comfortable place to rest and recharge. Come enjoy fresh air and quiet whether you are stopping through on a road trip or staying longer for local adventure. Fast WiFi for telecommuting!

Top guest favorite
A quaint wooden cottage entrance is framed by colorful prayer flags. A welcoming door leads inside, while a small seating area with a table and chairs is positioned on the porch. A wooden fence surrounds the outdoor space, enhancing privacy.
Home in Paonia
4.92 out of 5 average rating, 768 reviews

Private Cottage - King, Kitchen, Birders' Paradise

Kale's Cottage features a king size bed and is the epitome of unique and comfortable stays in Western Colorado. Our award-winning, pet-friendly Solargon boasts an elegant design, and is located just a half-mile walk away from the charming downtown of Paonia. The 374 sq ft space offers a fully stocked kitchen, seasonal wood stove, work/dining table & spacious private bathroom with shower. Whether for a special getaway, work, hiking, business or adventure, this is your perfect home away from home.

Top guest favorite
A spacious porch features wooden flooring and is lined with tranquil seating options, including a set of chairs and a swing. Natural light filters through the surrounding trees, enhancing the peaceful outdoor space.
Home in Delta County
4.96 out of 5 average rating, 285 reviews

2 Bedroom Ranch House

Just a mile off of Highway 65 sits Tongue Creek Ranch. The Ranch is located in the fertile valley junction of Tongue Creek & Surface Creek. Enjoy your own private 2 bed 1 bath ranch house. Both bedrooms have a super comfy pillow top queen size bed. WIFI is a fast 1gig fiber optic line. Enjoy a full kitchen, washer and dryer, and a sleeper sofa in the family room. The front patio is always in the shade. Ask about the optional cabin on site for use as a private detached room for overflow family.

Top guest favorite
A spacious log cabin features a charming facade with wooden shutters adorned by flower boxes. The surrounding landscape showcases rolling hills and a bright blue sky with scattered clouds, enhancing the rustic and inviting appearance of the home.
Home in Palisade
4.98 out of 5 average rating, 116 reviews

Peach Chalet, views, quiet, 5 min to downtown

No chores here, you're on vacation! Located just 4 miles from Palisade Rim Trailhead, home of the Palisade Plunge. The Peach Chalet is all yours, with plenty of room for your bikes! Privacy and views, plenty of room to relax indoors & out! Talbott's Cider House is a quarter-mile away, and downtown Palisade is 1.5 miles away. World-class wineries surround you! The Chalet is 2 bedrooms and 1 bath on main floor, loft and 2nd bath upstairs. Fully-stocked kitchen. Join us for your relaxing getaway!

Top guest favorite
The exterior of Blue Door Farm showcases a charming facade with a bright blue door and welcoming signage. A small table with two chairs sits under a tree, surrounded by well-maintained landscaping and a stone pathway that leads to the entrance.
Home in Grand Junction
4.99 out of 5 average rating, 190 reviews

Blue Door Farm Vacation Rental

Beautiful, sunny, and brand-new vacation rental in the heart of southwestern Colorado's peach and wine country. Blue Door Farm Vacation Rental LLC offers full accommodations for 1 to 6 guests, with sweeping views of the Grand Valley from the high desert to the Grand Mesa. It is a 15 minute drive to downtown Palisade and Grand Junction, and only 5 minutes to one hour's drive to amazing year-round outdoor recreation, including hiking, biking, skiing, agritourism, music festivals and wineries.

Guest favorite
Home in Palisade
4.92 out of 5 average rating, 233 reviews

The Pali House - 10 Acres & Wine Country Views

Welcome to The Pali House, a recently renovated 2-bed, 2-bath retreat on 10 private acres in Palisade wine country. Panoramic views, wrap-around porch, king bed, and the best stargazing in Colorado. Five minutes to wineries and dining, 40 minutes to Powderhorn. Designed for travelers seeking space, privacy, and stunning Western Slope sunsets. The home is extra large for groups of 4 and is fully stoked with everything you need to make Palisade home for a trip away. Your hosts, Joe & Trish

Top guest favorite
The farmhouse, featuring a classic white exterior and a sloped metal roof, is surrounded by lush greenery and colorful flower beds. A path leads from the gravel driveway to the welcoming entrance. In the backdrop, rugged cliffs rise, adding to the scenic rural setting.
Home in Palisade
4.98 out of 5 average rating, 197 reviews

A Peach of a Farmhouse

Located on the Scenic Fruit and Wine Byway, our newly remodeled air-conditioned farmhouse is on a three-acre peach farm within easy biking distance to Palisade. Enjoy downtown Palisade's farmers market, distillery, and brewery. We're moments from many wineries and trailheads including Mt. Garfield & Palisade Rim. Begin, end or spend your day lounging on the front porch in the shade of mature peach trees or enjoying views of the rugged Palisades seeming to rise just outside the back door.

Top guest favorite
A contemporary home is presented with a wooden exterior, surrounded by a gravel area. Large glass doors offer views into the interior space. Two outdoor chairs are positioned on the patio, with wildflowers and vegetation framing the scene.
Home in Loma
5 out of 5 average rating, 651 reviews

Fruita/Loma Guest House at the Perfect Day Getaway

This newly constructed "Green" home is a mix of modern and country styles and will surely inspire you to enjoy all of the outdoor activities the Grand Valley has to offer. The Perfect Day Getaway house is located on a quaint farm within 8 minutes of world-class hiking, mountain and road bicycling, and river rafting. It is a great launching point for day trips to Moab and the Grand Mesa as well! It was built to maximize the southern exposure and views of the Colorado National Monument.

Top guest favorite
A modern house is set against a clear night sky filled with stars. The exterior features large glass doors, providing a seamless view of the surroundings. A spacious patio area is visible, bordered by natural landscaping, creating a sense of tranquility and connection to nature.
Home in Palisade
4.97 out of 5 average rating, 154 reviews

Rapid Creek Retreat

High above the town of Palisade, nestled in the foothills of the Grand Mesa, is the Rapid Creek Retreat. Surrounded by untouched public land you will experience the true gift and grit of Colorado. Enjoy views of the big sky from sunrise to sunset and beyond for magical star gazing. We planned for this home to be ours, every detail of this home was built with intent and love. The feeling here is truly special. For those ‘rough around the edges. Sincerely, The Busch’s

Top guest favorite
A two-story house is seen from the outdoor area, featuring a patio with several chairs and tables. A gravel driveway leads to lush vineyards in the background, framed by distant mountains under a clear blue sky.
Home in Palisade
5 out of 5 average rating, 128 reviews

Love Orchard

You will enjoy breathtaking endless views of orchards, vineyards and the Bookcliff mountains and amazing sunsets from the bright, open great room and balcony. You may think you are in the clouds! The peace and quiet you will feel in this lovely new home will surely refresh you. Located on the fruit and wine byway, there are 6 wineries within 3 miles yet you are only 2.5 miles from downtown Palisade and its plentiful offerings. This home is calling your name!

Top guest favorite
An expansive view of the West Elks mountain range is visible from the front porch. A wooden railing frames the scene, while a fire pit area is situated on the ground below. Lush fields and rolling hills stretch toward the mountains under a clear blue sky.
Home in Crawford
4.98 out of 5 average rating, 111 reviews

Needle Rock View Retreat

Feast your eyes on this awesome and unobstructed view of the West Elks mountain range and Grand Mesa from our big front porch! The house features 3 bedrooms, 2 bathrooms, living room with sleeper sofa, kitchen, dining area, and a second living area downstairs. Outside you’ll find a patio with fire pit where you can sit around a campfire and enjoy the incredible view of Needle Rock and surrounding mountains. We also offer an RV site with full hookup.

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