
House vacation rentals in Mebane
Find and book unique houses on Airbnb
Quick stats about house rentals in Mebane

Total vacation rentals
Explore 30 vacation rentals in Mebane

Nightly prices starting at
Mebane vacation rentals start at ﺩ.ﺇ 110 per night before taxes and fees

Verified guest reviews
Over 660 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
30 of Mebane vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mebane rentals

4.9 Average rating
Mebane stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in Mebane
Guests agree: these houses are highly rated for location, cleanliness, and more.

1920s Historic Retreat in Downtown Graham
Step into a refined home where history & comfort meet. Built with enduring charm and restored with care, this elegant heritage retreat blends period details with modern indulgences - crafted for guests who appreciate quality in every detail. Whether you're preparing a casual breakfast or hosting a family gathering, our gourmet kitchen is fully equipped for culinary creativity. You'll find premium cookware, an induction cooktop for quicker meal prep, and ample space to cook, connect, and savor.
LocationFamilyLaundry

Pet-Friendly Ranch Near Elon U
Enjoy this comfortable 1-level home for your Burlington stay! In a quiet established neighborhood and close to all things - hospitals, interstate access, shopping, restaurants. 12 Minutes to Elon's campus, 12 minutes to Springwood Park soccer & baseball fields. Stocked kitchen, two living areas, two dining areas, work station, comfortable beds, TVs in each bedroom, large back deck, gas grill, pack n play on site. Ample driveway parking space. Well-behaved dogs are welcome! Non-smoking home.
ValueFamilyOutdoor spaces

Elon Southern Charmer~Fenced Yard~Pets Welcome
Located only 1.3 miles from the Center of Elon University's Campus off University Drive~Interstate 40/85 is 5 minutes away~Close to Shopping & Local Restaurants~Corner Lot in Small Neighborhood has 6' Private Fenced Backyard~Pet Friendly~Back Deck~All New LVP~No Carpet~Freshly Painted~Tasteful Decor~Soft Memory Foam Mattresses, King & 2 Queen Beds~New Samsung TV's in all Bedrooms & Living Room~Washer & Dryer~Blackout Curtains in Bedrooms~Attentive local host~Ready for you to have a great stay!
ValueFamilyCleanliness

Artist-Designed Cabin Near Duke & Downtown
Relax and recharge in a modern, artist-designed passive solar home tucked into the woods just minutes from downtown Durham and Duke University. This cabin-style retreat blends nature, comfort, and convenience — ideal for weekend getaways, visiting Duke, or extended stays. Inside you’ll find original artwork, abundant natural light, and a professionally equipped kitchen. Outside, enjoy birdsong and mature trees while staying close to Durham’s restaurants, coffee shops, breweries, and shopping.
ValueFamilyCondition

The Bee & Bee (6.7 Miles to Elon). 4BR (KQQQ)/2Ba
It is just 6.7 miles / 15 minutes to Elon University, from this charming, recently renovated, centrally-located 4 Bedroom / 2 Bath home perfectly nestled in a peaceful neighborhood within walking distance of downtown Graham, North Carolina. Within 20 miles to UNC and 23 miles to Duke University, this home is the perfect place for the whole family to stay together for graduations or other special events at any of these universities. Come relax on our deck and experience small town living!
LocationValueWifi

Luxurious Modernist Tree House
Stunning, private, and truly one-of-a-kind—this unique home is perfect for a vacation, staycation, special occasion, or simply celebrating everyday life. Designed by renowned modernist architect Frank Harmon. The 2,128-square-foot residence sits on 1.3 acres and was crafted with meticulous attention to detail. Inside, you’ll feel nestled among the treetops while remaining conveniently close to restaurants, shopping, downtown Raleigh, WakeMed, UNC, Duke, and Research Triangle Park.
LocationFamilyParking

Walk to Downtown Hillsborough • Dog Friendly
More than just a vacation rental, this is a home we love and are happy to share. Tucked into a quiet, walkable neighborhood near historic downtown Hillsborough, you can walk to restaurants, coffee shops, galleries, Gold Park, the Riverwalk, and the Eno River, then come home to relax on the porch or in the fenced backyard. Thoughtfully stocked for comfortable everyday living, it’s ideal for weekend getaways, weddings, family visits, and trips to Duke or UNC. Dogs are welcome, too.
FamilyLocationSleep quality

Bluebird Bungalow, walk to downtown
Stylish 1920s historic home one and a half blocks from the adorable downtown Graham. Short walk to breweries, restaurants, coffee shops and minutes from Elon University, Labcorp and Tanger Outlets. Our home is a great central location situated between Chapel Hill and Greensboro and minutes from hiking and kayaking locations on the Haw River. Plush linens, mattresses, and stocked with amazing bath soaps. This is the perfect location for exploring North Carolina’s Piedmont region!
LocationValueBackyard

Hot Tub + Walk to Downtown | Fire Pit | Game Table
Hot tub, fire pit vibes, and walkable downtown access—this cozy 2BR getaway is made for relaxing and reconnecting. Unwind in the 8-person spa, stroll to local restaurants & breweries, or enjoy game night with a convertible pool table. •Large 8-person hot tub/spa •Outdoor seating + custom fireplace •Walkable to downtown (restaurants, breweries & shops) •Convertible bumper pool/dining table •Smart TVs in every room •Fully stocked kitchen + cocktail glassware
FamilyLocationIndoor spaces

Cozy home away from home.
Charming house in quiet family neighborhood. private bedrooms off from family entertainment room. Kitchen has wooden cabinetry , professional series of appliances includes dishwasher, washing machine, tea kettle all cookware to prepare a gourmet meal. Bookings have been coming fast. Only 5 miles from Elon University. Email me to guarantee your reservation. I am looking forward to hosting great people so email me to book your travel plans.
FamilyLocationKitchen

1910 Mill House | Fenced Yard | EV Charger.
Escape to Clayton's Place, a restored 1910 lake-view mill house perfect for 4 guests. This pet-friendly retreat features 2 bedrooms (king, bunks), a modern kitchen, a dedicated workspace with fast Wi-Fi, and a large fenced yard. Enjoy serene mornings on the porch, evenings by the fire pit, and the convenience of an on-site EV charger. A peaceful, historic getaway just minutes from Mebane, Burlington, and Elon University.
LocationValueCheckout

Charming Home with a Huge Fenced Yard
Charming 3BR/1BA Burlington ranch, your perfect road trip stop or cozy retreat! Comfortably sleeps larger groups with a queen bed & two trundle beds. Unwind with the 65-inch TV, or relax in the expansive backyard with a BBQ grill. Perfectly located near I-85/40 for easy access to Elon College, Greensboro, and local shopping. Your ideal home away from home awaits!
FamilyValueSleep quality
Popular amenities for Mebane house rentals
House rentals with a pool

UNC Cottage- near Univ/Hospital, YMCA, Franklin St
FamilyValueBathroom

Luxe Home 4 Mins Duke/DPAC | King Beds, BBQ, Pool
FamilyLocationAccess

Spacious 3bd Lake & pool near Duke UNC Southpoint
ValueLocationBackyard

Cozy 2-bed, 2.5 bath near UNC
LocationFamilyCheckout

Serene Landing Place near Downtown Cary
LocationValueDecor

The Aqua Haven l4B2.5Bl Pool&Spacious yard near DT
FamilyValueView

Quiet home near Lake & Outlets
FamilyLocationLayout

Luxury Retreat w/Salt Pool & Hydrotherapy Hot Tub
FamilyLocationIndoor spaces
Weekly house rentals

Country Comfort Entire House for Perfect Get-away
LocationFamilyAccuracy

Gem of a House by River near Chapel Hill
LocationValueHospitality

327 Beautiful Residence in Mebane NC.
FamilyLocationBathroom

home for workers, families, university students.
LocationValueSleep quality

Mebane's Hidden Gem | Hosts up to 10 Guests
LocationFamilyCheckout

Spacious Retreat w/ King Suite, 3 Baths + Yard
FamilyLocationCleanliness

Newly Updated Home w/Easy Access to I-85/I-40
FamilyValueSleep quality

Simple Living
LocationValueGetting around
Private house rentals

Southern Front Porch, Newly Renovated, Comfortable
FamilyValueOutdoor spaces

The Farrell - 3bed/1bath Cozy home!
FamilyLocationLaundry

Restored 1940s Home• King Bed• Pet-Friendly
LocationSleep qualityPets

Vintage charm/comfort, 2 ml to Elon, private lot
ValueLocationKitchen

Cozy 3BR w/ Fenced Yard & Porch- Pets Welcome!
LocationFamilyAccuracy

5 Min to Elon | 7 Min to Downtown | Washer + Dryer
FamilyLocationCleanliness

4 Min to Downtown | 10 to Elon | Car Rental Avail.
FamilyLocationComfort

Cozy farmhouse with beautiful lake views
LocationValueIndoor spaces
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- Duke University
- North Carolina Zoo
- North Carolina State University
- PNC Arena
- Raleigh Convention Center
- University of North Carolina at Chapel Hill
- Raven Rock State Park
- Greensboro Science Center
- Wet'n Wild Emerald Pointe Water Park
- Virginia International Raceway
- Greensboro Coliseum Complex
- Crabtree Valley Mall
- Elon University
- University Of North Carolina At Greensboro
- Sarah P. Duke Gardens
- William B. Umstead State Park
- North Carolina Museum of Art
- North Carolina Museum of Natural Sciences
- Eno River State Park
- Lake Johnson Park
- Durham Bulls Athletic Park
- Duke Chapel
- Frankie's Fun Park
- American Tobacco Campus





