
Vacation rentals in Manzanita Canyon Open Space
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Manzanita Canyon Open Space
Guests agree: these stays are highly rated for location, cleanliness, and more.

Midcity Retreat
Chic studio in central San Diego! Enjoy a full kitchen, in-unit washer/dryer, WiFi, and wall-mounted AC with heating and backup heater. Located on Thorn St with easy access to I-8, I-15, I-805 & I-94, minutes to downtown and Balboa Park. Perfect for solo travelers or couples (max 2 guests). A small neighborhood market is a 1-minute walk away. Please note: this is a simple, comfortable stay in a working San Diego neighborhood—not a luxury or beachfront property. No baby items (cribs/high chairs).

Private Entry | Crisp Sheets | Cozy Grotto Shower
Think of this like a hotel room or a minimalist studio. The entire unit is: - ONE compact room - Bathroom - Private entrance There is no kitchen or living room. It's attached to my house. The room has a velvet couch that converts into a full sized bed. The bed is extremely comfy with its 2" topper. It will be ready as a bed upon arrival & is easy to convert into a couch. There is are two fans, a desk, fridge/freezer, coffee machine, coffee, utensils, plates, bowls, washer/dryer & detergent.

Private, bright, cozy getaway with full kitchen
Experience a delightful getaway in this beautifully remodeled and centrally located guest suite. With its bright and inviting living space, it’s perfect for relaxation during the day and transforms into a cozy retreat at night. Sleeps up to four guests, the sofa easily converts into a full bed. Just 10-20 minutes from landmarks such as SDSU, Downtown, Little Italy, Gaslamp, San Diego Zoo, SeaWorld, Mission Bay, and concert venues. This is a 2nd floor unit, so guests will need to navigate stairs

Stunning 2BR/2BA| Plunge Pool, AC, Private
Modern 2 bed|2 full bath in the heart of San Diego. Featuring trendy interiors, stock tank pool, and thoughtful amenities, this space is designed for relaxation & comfort. Enjoy seamless indoor-outdoor living with cozy touches that make you feel at home. Casa Luna is perfectly located minutes from North Park, Downtown, Balboa Park, the zoo, close to beaches & a vibrant dining scene. Whether you’re here to unwind or explore, Casa Luna is your ideal home for an unforgettable San Diego experience.

California Dreaming l Hot tub l Private Backyard
Welcome to our stylist and charming Home. This home is completely remodeled with 3-bedrooms/2-bath, fully furnished. Centrally located in a quiet neighborhood, walkable to grocery stores, and close to the best open parks and beaches of San Diego. Only a few minutes to all the amazing San Diego has to offer. 5 miles from SDSU 9 miles from San Diego airport 5 miles from San Diego zoo 10 miles from seaworld 8 miles to downtown SD 10 miles from Coronado island 10 miles from Naval Base Station SD

Private Patio Garden Suite in North Park on Canyon
Canyon garden patio guest suite built in 1932 with tons of charm, modern furniture, and easy access to everything San Diego has to offer! The suite has a private entrance from the main Spanish Colonial Revival home via the patio garden and looks out onto a lush canyon. Open your door & enjoy the plant-filled patio for dining, lounging, & relaxing. Fast WiFi & A/C. Professionally cleaned & sanitized for every guest. Close to the zoo, Balboa Park, & the restaurants & bars North Park has to offer!

Stylish Bungalow in Walkable South Park Location
Step into San Diego history with this charming 1-bedroom bungalow, tucked away in the heart of eclectic South Park – one of the city’s coolest neighborhoods. Sip coffee in the courtyard and stroll to boutique shops, vintage finds, European-style cafés, wine bars, great eateries and local breweries all right outside your door and within easy walking distance. Located just minutes to Downtown, Balboa Park and the world-famous zoo and only 6 miles from the airport. Laid-back adventures start here.

North Park home, hot tub, near Balboa Park & Zoo!
North Park home with a backyard built for the best nights of your trip! Soak in the hot tub under the stars, light the firepit, and fire up the Weber or walk to dinner down the street. Little Bird Brewing and Grand Ole BBQ are a 10-minute walk. 3 bedrooms (king, queen, double/full), living room with a sleeper sofa, full kitchen, 600 Mbps WiFi, free parking. Balboa Park is 5 minutes away, the Zoo is 10, and the ocean is just 20 when you're ready for it. Come for San Diego, *stay for the home*

Hot Tub & Sauna | San Diego Getaway
Looking for a place to thoroughly relax and reset, while soaking into a private hot tub and infrared sauna? Looking for a peaceful home with a dedicated workspace, A/C, HD monitor, and high-speed WiFi? Looking to stay central to San Diego's eclectic neighborhoods while being tucked away on a quiet residential street? Looking for an efficient apartment with brand new appliances? This is the place for you! Petco Park / Downtown ~ 10 min. Pacific Beach/La Jolla ~ 20 min. Old Town ~ 13 min.

Private Studio
Enjoy a cozy studio all to yourself, just minutes from University Ave, walking distance to shopping and food like Denny's Jamba Juice and Starbucks. Less than 15 min to Gaslamp (Downtownthe San Diego zoo, North Park, the 805, 15, and other great places nearby. This is a unit with a private entrance and black out shades and a gated driveway for security. California King with plush top Serta mattress. check in can be earlier. Please ask PLEASE READ INFO to ensure it's a fit for you.

Tranquil Airy San Diego Home
Welcome to your peaceful home-away-from-home! This charming & spacious TWO STORY house offers the perfect blend of comfort, privacy, and convenience. Nestled in a quiet neighborhood cul-de-sac, yet just minutes drive from everything, this is the ideal spot for both relaxation and exploration. It's the perfect space for a couple, a group of friends, a small family (with kids aged 12 & above) or remote workers looking to relax and enjoy San Diego’s beautiful weather year round.

La Casita South Park
San Diego's best neighborhood in this private and beautiful apartment with parking. King bed in the bedroom, cozy living room with a queen sofa bed. Walking distance to restaurants, shops, bars. 5 minutes from Balboa Park and the Zoo, 10 minutes away from Convention Center/Downtown with a full kitchen, washer/dryer, WiFi, and air conditioning. The apartment has everything you need for your California vacation!
Popular amenities for Manzanita Canyon Open Space vacation rentals
Other great vacation rentals in Manzanita Canyon Open Space

Canyon View Casita

Central Oasis with Big Yard and Private Patio

Honeycomb Hideout

Lovely Canyon-View Home Quiet, Private & Central

SD Spool Oasis-4 BR, 3 BA, Sleeps 15| Free Parking

Stylist central SD 2BR1BA/ WD + fenced parking

A charming stay in South Park, San Diego

Parkside 2BDR Retreat| Patio/Parking for 4
Destinations to explore
- SeaWorld San Diego
- Coronado Beach
- Rosarito Beach
- LEGOLAND California
- University of California-San Diego
- San Diego Zoo
- Petco Park
- San Diego Zoo Safari Park
- San Diego Convention Center E Ent
- Pacific Beach
- Balboa Park
- Tijuana Beach
- Pechanga Resort Casino
- San Diego State University
- Torrey Pines State Beach
- Mission Beach
- Oceanside City Beach
- Ocean Front Walk
- Las Olas Resort & Spa
- Moonlight State Beach
- La Misión Beach
- Belmont Park
- Sesame Place San Diego
- South Mission Beach, San Diego





