Vacation rentals in Lyon

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Top-rated vacation rentals in Lyon

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Guest favorite
A vibrant building exterior features a large mural depicting musicians and guitars. The entrance to Delta Digs is marked by an arrow, drawing attention to its location amidst the colorful artwork. Windows along the facade showcase a lively atmosphere.
Apartment in Clarksdale
4.92 out of 5 average rating, 147 reviews

Delta Digs-the place to lay it down

Delta Digs is a fabulous new vacation rental designed, built, and decorated in true Delta style by local artisans. The 425 square foot, ground level (no stairs) flat is newly constructed in the circa 1897 Clarksdale Telegraph Office at Second & Delta in the heart of the Historic District downtown. Featuring a Queen-size bed with PosturePedic mattress and Magic Fingers, hardwood floors, diner booth from a classic diner, elegant leather sofa & oversize chair, 4 foot X 5 foot custom shower with Speakman faucets, new bath and vanity, Central heating and air conditioning,refrigerator, coffee maker, microwave, HD flat screen TV with DirecTV, & stereo. 600 count 100% Cotton Sheets, Down Pillows,and 100% Cotton bath towels. We feature original artwork by many Mississippi artists (painters,photographers,designers). Location,location,location. Located across the street from Hambone Art Gallery and the Rock & Blues Museum, and around the corner from restaurants Yazoo Pass, Gradma's Pancakes, Bluesberry, Stone Pony, and Levon's Bar & Grill. Blues clubs Ground Zero Blues Club and Red's are within a 4 minute stroll. The New Roxy and the Delta Blues Museum are within 3 blocks. There is a wine and spirits shop, plus a convenience store within the block. Art gallerys, gift shops, and CatHead Records Folk Art and Blues Store are all within one block of our front door.

Guest favorite
A cozy sitting area is presented with comfortable seating and a television. Light-colored walls are complemented by wood accents. A small table is situated near the doorway, while a refrigerator is visible in the background. A colorful rug enriches the space.
Casa particular in Lyon
4.96 out of 5 average rating, 47 reviews

Safest Place in Clarksdale Come Visit With Us

The barn house apartment is cozy and comfortable with 2 spacious bedrooms, 1 and a half baths, laundry room., full kitchen and sitting area. Close and easy access to downtown Clarksdale and Helena, AR for blues fans. 5 miles from Ground Zero Blues Club and downtown Clarksdale 5 miles from historic Hwy 49 & Hwy 61 Crossroads 20 miles from Moon Lake 26 miles from Isle of Capri Casino 4.4 miles from Northwest Regional Medical Center 20 miles from O'keef WMA 75 miles from Memphis Intl Airport

Guest favorite
The exterior of the home features a vibrant yellow front door, flanked by decorative plants. The brick facade and large windows provide a welcoming entrance. A well-maintained lawn surrounds the front, enhancing the inviting appearance of the property.
Home in Clarksdale
5 out of 5 average rating, 32 reviews

Delta Dream Retreat (Entire Home)

Relax with the whole family at this peaceful place to stay. we have put our heart and soul into renovating this entire home with all new appliances , bedding, furniture, mattresses, etc. It Is very modern and comfortable for families. It incl wi-fi, usb and multi movie channels every room, games, coffee, water, tea, and complimentary snacks. Only one camera[ring door bell] at the front door. Great neighbors and less than 2m from downtown Blues venues, Historical Crossroads, & eateries.

Superhost
A single-story home presents a classic brick façade with a prominent garage. The well-kept yard features neatly trimmed shrubs and lush greenery. The driveway leads to the garage, providing ample parking space. Large windows allow natural light to enter the living spaces.
Home in Clarksdale
4.73 out of 5 average rating, 174 reviews

Down Home Southern Charmer

This is the home that my sister and I grew up in with our parents and younger brother, who have passed on. We love our home, and are now opening it up to guests from anywhere in the world who want a comfortable place to stay while visiting the Mississippi Delta. Available to our guests are a centrally heated and cooled home with two bedrooms, a living/dining room, a family room with TV and Internet, two bathrooms, a kitchen, washer and dryer, and a garage. And, we just put in new floors!

Superhost
A cozy living area features two light-colored sofas opposite each other, adorned with decorative pillows. An intricate area rug covers the floor, complementing the rustic wooden walls and high ceiling. A room divider is positioned in the background, dividing the space from the bedroom. Natural light filters through the nearby windows.
Cottage in Clarksdale
4.91 out of 5 average rating, 320 reviews

Sunflower Cottage on the River

Only a mile from historic home of the blues, Clarksdale in a gated community. The cottage sits on the banks of the Sunflower River with beautiful views of rustic woods. Out your window you might see deer, fox & other wildlife. Take a walk along the riverbank. You’ll enjoy relaxing in the comfy beds, ,enjoy privacy, the piano , & closeness to all the blues music venues. It has two fire pits, an outside grill & full kitchen. Great for couples, adventurers, business travelers , musicians ,

Guest favorite
A charming blue cottage features a gabled roof and a white front door framed by two light fixtures. Two vintage chairs are positioned on the grassy area in front, surrounded by mature trees that provide some shade.
Cottage in Clarksdale
4.83 out of 5 average rating, 173 reviews

The Gallery at Chateau Debris

Welcome to The Gallery! This one-bedroom cottage sits behind the main house. It has recently been renovated, but is decorated with vintage furnishings for personality. The cottage is equipped with a full kitchen, bedroom, bathroom, washer and dryer, & Roku TV. Your stay will be unique, as the decor has been selected from my collector's lair, and the best part is - it's all for sale! The Gallery is a live-in collectibles showroom so, contrary to the saying - you CAN take it with you!

Guest favorite
The living area features two comfortable sofas with coordinating patterned pillows. A glass coffee table sits in between, and a dining table with two chairs is positioned nearby. Natural light streams through the large windows dressed with sheer curtains.
Loft in Clarksdale
4.87 out of 5 average rating, 23 reviews

Sunflower Lofts C

Welcome to The Sunflower Lofts! These modern, fully furnished apartment style accommodations are located in the heart of downtown Clarksdale. With a coffee shop just a few doors down and all the best restaurants & music venues within walking distance, you won't even need to get in the car until you leave! We accept long and short-term guests, so stay with us for one night or a few weeks! No pets. No smoking. Quiet hours begin at 10:00 pm. We do not accept local reservations.

Superhost
A modern gourmet kitchen is presented with sleek cabinetry and contrasting black and white elements. A spacious island with seating for four is illuminated by pendant lights. Open shelving displays dishware, while the stainless-steel appliances enhance functionality.
Apartment in Helena-West Helena
4.88 out of 5 average rating, 33 reviews

Luxury Apartment Downtown Helena

Conveniently located near historic landmarks, local shops & renowned dining establishments. Explore the rich cultural heritage of Helena, from museums to live music venues, all within walking distance. Amenities • Self-check-in • Video surveillance/exterior of building • High-speed Wi-Fi • Smart TV • Coffee machine • Central air & heating • Free reserved parking on premises • Responsive & accommodating hosts • Strict cleaning protocols • Safe & secure building

Superhost
A spacious bedroom is equipped with two queen-sized beds, each dressed in soft blue bedding. A cozy couch is positioned nearby, and decorative wall art adorns the grey walls. Natural light filters through window treatments, enhancing the inviting atmosphere.
Home in Lambert
4.84 out of 5 average rating, 25 reviews

Southern Charm

Relax with the whole family at this peaceful place to stay. You'll have three bedrooms and four queen sized beds for your enjoyment. A very spacious living/dining room area for the whole family to sit and chat. There is also two full-sized bathrooms. Also included is a screened in outdoor porch with plenty of seating. There is onsite laundry accommodations and a complete kitchen with all the ammenities.

Superhost
Home in Mound Bayou
4.8 out of 5 average rating, 5 reviews

Beautiful luxurious 2 bedroom!

This luxury 2-bedroom home offers hardwood floors, an open-concept layout, and abundant natural light. The gourmet kitchen features quartz countertops, stovetop and a small dining space. Both bedrooms are furnished with plush queen beds and quality linens. Elegant crystal lighting is showcased throughout, adding sophistication and charm to every room, creating a warm and inviting upscale retreat.”

Top guest favorite
The brick exterior of Blues Hound Flat is characterized by large glass block windows and a centrally positioned red door. Horizontal blinds cover the windows, providing a sense of privacy while allowing light to filter through. A small air conditioning unit is visible above the door.
Loft in Clarksdale
4.93 out of 5 average rating, 445 reviews

Blues Hound Flat

Blues Hound Flat sits quietly across from the historic Greyhound bus station in the center of downtown Clarksdale. Step outside, and you're in the heart of the Delta Blues, surrounded by local eateries, shops, bars, and music venues! The air itself is heavy with the traditions of the Delta. This loft-style flat features all the basic amenities one could want and solitude when needed.

Guest favorite
The living area features exposed brick walls and large windows, providing natural light. A cozy couch is complemented by two side tables and lamps on either side. A decorative coffee table enhances the inviting atmosphere of the space.
Apartment in Clarksdale
4.91 out of 5 average rating, 35 reviews

High Cotton Condo Unit D

High Cotton Condo Unit D is centrally located in heart of downtown Clarksdale with 2 bedroom, 2 baths, and a foldout couch in the living room. This unit is updated and fresh with a large living room, a modern kitchen, and great retractable windows that look out onto Delta Avenue below! Condo D has all the modern luxuries you need to make your trip to Clarksdale complete!  

Popular amenities for Lyon vacation rentals

  1. Airbnb
  2. United States
  3. Mississippi
  4. Coahoma County
  5. Lyon