Guesthouse vacation rentals in Lexington County

Doc & Amy's Downstairs R&B Studio

Fishermen! Enjoy a safe secure location with plenty of parking! This studio has a very classy yet groovy feel, the main colors are Red & Black. Originally this was going to be a room for our pool table. So it gives off that feel with the tile on the walls, the sporty bathroom (with a urinal), the lighting in the room, and a very nice sound system. We are excited to share this awesome space with you. If you are traveling with other persons there is another similarly well equipped space upstairs

Detached Garage Studio in Beautiful Neighborhood!

Enjoy our beautiful neighborhood in Irmo, SC close to I-26 at our wonderful small studio (~280 sq ft) over our garage! Best for a 1-2 night trip as this is a smaller studio. The space has a mini kitchen area with microwave, stove top, mini-oven/air fryer, Keurig, and more. All space is in one studio area with a bathroom. 4 occupancy based off of a twin trundle bed with twin that rolls out underneath… and then a queen air mattress. Best for 2 adult + 2 children, 4 adults would be crowded.

Lake front Lake Murray in the Heart of Lexington

Walk out onto Lake Murray in the heart of Lexington! From sunrise to sunset this home is perfect for that relaxing get away; a private beach is steps from your door, a dock to fish from, boat ramp to launch your lake toys, quite cove with beautiful wild life! As the owners we live in the upstairs of the home (completely securely separated) and are available if you need anything! We enjoy sharing this beautiful home with others! Please note the beach, dock and lake are shared spaces.

Cozy 1-Bedroom Guesthouse Walking Distance to USC

Keep it simple at this peaceful and centrally-located place, with lovely garden views. 1 bedroom/1 bath apartment with a twin sized day bed in the living room. Full kitchen. Walking distance to USC and Five Points. Close to Williams Brice Stadium (1.5 miles); Fort Jackson (5 miles); Soda City Market, Main Street, the Capital building, and the Koger Center (1 mile plus). Parking in driveway or on the street using our guest parking pass. City of Columbia License No. BL002050-08-2023

Restful Refuge

Restful Refuge is a renovated one-bedroom studio apartment that includes a full kitchen and full bath downstairs to our home. For your stay with us you will have a private entrance. We are located just minutes from Downtown Columbia but secluded in a small community on a pond. Our desire is to provide a place to help you unwind & rejuvenate during your time in Columbia. Whether you are in town for business or pleasure, we would love to share our Restful Refuge with you.

❃ The Rosewood Loft ❃ Desk, Kitchen & Laundry

Wonderfully comfortable, quiet, clean, and spacious loft in the heart of Rosewood, one of Columbia's most convenient, safe, and popular neighborhoods! ★ 8-minute drive to Founders Park, home of USC Baseball. ★ Minutes from USC campus, Fort Jackson and downtown Columbia. ★ 6 min walk to groceries (Publix), several restaurants and a brewery. ★ Quiet and walkable neighborhood. ★ Secure, off-street, 1-car parking behind a 6' fence. ★ Seamless check-in with keypad lock.

High Honey

A well-appointed space walking distance from the Governor's Complex, Lace House & Gardens, and newly revitalized Finley Park. Near downtown and easy access to major highways. A fully equipped kitchen and two restaurants just steps away make dining easy—no matter your style. Bright and whimsical, the space offers all the comforts of home with the convenience of a central location. Stay through Sunday and check out Monday to unlock extra availability at a discount.

Lizzi & Scott’sTiny Guest House secluded USC-Vista

Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in.

Capers Guesthouse |Private 1BR Retreat

Enjoy a private, comfortable stay in this fully renovated 1-bedroom guesthouse in the Rosewood neighborhood. A great alternative to a hotel, offering more privacy and space to unwind. This detached bungalow is fully equipped for a relaxing short or extended stay. Inside you’ll find a cozy living area, full kitchen, private bedroom, and everything you need for a comfortable home base while traveling. Ideal for couples, solo travelers, or business stays.

Lakefront guesthouse with private dock.

Welcome to the Loft at Lake Murray. This new 2 bedroom house is the perfect place for a getaway. It features its own private dock, large patio, open floor plan with a fully stocked kitchen, pullout couch, washer + dryer and much more. Its in a quiet cove that is perfect for swimming, kayaking and paddle boarding. Close to downtown Chapin and Dreher Island. Come fish right off the dock. We have added power at the dock for easy charging.

Writer's haven in private guesthouse.

Cozy guesthouse makes an ideal writer's retreat! Located in an attractive, quiet neighborhood close to dining and shopping. On-street parking on non-busy side street. Hosts will work with you on creating fun rewards for writing goals. Space has a microwave, refrigerator, coffee maker, and electric kettle, and hosts will provide coffee, tea, wine, bottled water, and snacks, as well as continental breakfast.

Brand New Studio Guest House with Full Kitchen.

Enjoy a stylish experience at this centrally-located house. Within a one mile radius of downtown Columbia, University of South Carolina, Benedict College stadium, Prism Health Richland Hospital, Prism Health Baptist Hospital and MUSC medical center. Fort Jackson is less than 10 minutes away! Certified service animals only are welcomed with a fee. There is also a fee for guest under the age of 25.