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Vacation rentals in Las Cruces

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Las Cruces

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Centro
4.95 out of 5 average rating, 22 reviews

Modern, independent house with barbecue area + private garage

💎 Modern, Independent, Centrally Located House in the Best and Safest Area of Santa Cruz, Ideal for Meetings 🥳. Just a short walk from 24-hour supermarkets, a mall, hospitals, and pharmacies. It features 3 bedrooms (1 en suite), 4 full bathrooms, a spacious living and dining room, a fully equipped kitchen, and a barbecue grill in a private patio. Ideal for families or friends 🫂 looking for comfort and privacy, strategically located to enjoy the best of the city in total comfort, style, and safety. Private parking for one vehicle

Superhost
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 3 reviews

Luxury and views in Mar Adentro

Treat yourself to a getaway without leaving the city and experience Mar Adentro from this spacious apartment in the newest and most exclusive tower. Wake up to beach views, relax on your private terrace with a barbecue grill, and enjoy an elegant living room with Bose sound, a 70” TV, streaming, and internet. Includes a fully equipped kitchen, a bedroom with a walk-in closet and private bathroom, a washing machine, and free parking. Enjoy access to the beach, restaurants, a tiki bar, and water activities for your relaxation.

Superhost
A tranquil area is featured, showcasing a large, shimmering lagoon with palm trees lining the shore. Colorful, casual seating is visible on the sandy ground, providing spots for relaxation. The clear blue sky is dotted with a few clouds, enhancing the serene environment.
Home in Santa Cruz de la Sierra
4.87 out of 5 average rating, 23 reviews

Davezies House, A Unique Experience, Inland Sea

​Discover a sublime and captivating retreat! A gem with 2 suites, including an impressive master suite. Enjoy spacious and elegant spaces in the living/dining room and an open-plan gourmet kitchen. Relax by the pool or at the barbecue area, ideal for creating memorable moments with family and friends. Air conditioning, TV, and fast Wi-Fi; comfort is guaranteed. Access to exclusive areas: beach, restaurant, tiki bar, children's areas, and more. We look forward to seeing you! Book now and secure your dates!

Top guest favorite
An expansive rooftop pool is illuminated by soft lighting, reflecting the city skyline at night. Lounge chairs are neatly arranged along the pool's edge, and the sleek wooden deck complements the modern aesthetic of the space.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 154 reviews

Luxurious and modern apartment. Equipetrol Sky Elite

This luxurious studio is located in the Equipetrol neighborhood, Sky Elite Building, one block from the Los Tajibos Hotel; it represents the perfect combination of exclusivity and first-class amenities in the city of Santa Cruz de la Sierra, surrounded by restaurants, shops, cafes, pharmacies and supermarkets. The building offers more than 3,000 square meters of social areas including a modern gym, extensive swimming pool, barbecue, coworking, private movie theater, sauna and whirlpool.

Top guest favorite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 51 reviews

Green Tower, Luxury, Views from the 26th Floor

Enjoy your stay in the most spacious, roomy, and tallest Airbnb in Santa Cruz, where everything is close by and in the best building in the city. On the premises, you can enjoy a swimming pool, a steam sauna, and spectacular views from the 26th floor of the beautiful Manzana 40 building and the iconic Pirai River. Steps from supermarket, restaurants, malls, banks, spa, etc. The beautiful and luxurious restaurants Cielo Sky Bar (rooftop), Jardin de Asia and more are in the same building.

Guest favorite
A shaded seating area with a comfortable chair and decorative cushions is positioned under a canopy. Lush greenery frames the space, with views of a large pool and sandy beach just steps away. The scene is complemented by palm trees lining the water's edge.
Apartment in Santa Cruz de la Sierra
4.87 out of 5 average rating, 78 reviews

Mar Adentro 1st row SANTA CRUZ

Front row ground floor apartment with ocean views. Walk just a few steps and you'll be enjoying one of the largest pools in Latin America. Live a Caribbean dream in the heart of Santa Cruz. This one-bedroom apartment invites you to enjoy its spacious living room, large patio and private barbecue with all the luxury you deserve. Let yourself be captivated by the majestic beach with crystal clear water in the most beautiful and best located space of the condominium.

Guest favorite
An outdoor pool is featured on a rooftop terrace, offering panoramic views of the city. Surrounding palm trees and lounge chairs provide a relaxing environment. The clear water contrasts with the light-colored tiles and the modern building structure in the background.
Apartment in Santa Cruz de la Sierra
4.94 out of 5 average rating, 68 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Superhost
Apartment in Santa Cruz de la Sierra
4.88 out of 5 average rating, 17 reviews

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

Top guest favorite
A grassy pathway leads through a shaded arbor draped with greenery, connecting to a country house with a red-tiled roof. Two friendly dogs stroll along the path, which is framed by vibrant palm trees and a clear blue sky with scattered clouds.
Cabin in La Guardia
4.96 out of 5 average rating, 27 reviews

Casa Quinta Aristogato

Ideal country house for relaxing and celebrating with friends and family. It has gardens, trees, and a blend of rustic charm and modern amenities. The common areas are enormous, featuring furniture that invites relaxation and spectacular views of the valleys. The property is spacious, with pathways that connect you with nature. The bedrooms are super comfortable and tastefully decorated. You're going to love it!

Superhost
Cabin in La Guardia
4.79 out of 5 average rating, 19 reviews

Machi Casiopea Eco-lodge

Relax and enjoy a moment with nature, 10 minutes from the municipality of La Guardia and 3 minutes from the tranca al Torno entering through Cañada Seca. Room with air conditioning, 2 1/2-seater bed with option to add 1 extra mattress; Grill, electricity, water, wifi, ample space for hiking trails. Fruit trees, easy access with nearby shops to get food. Owners live on site. A unique and quiet getaway.

Guest favorite
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 15 reviews

The best view of Santa Cruz

From this apartment in the best area of Santa Cruz (Equipetrol Norte, in the business center) you will have the best apartment with a pleasant climate. It is located on the 16th floor, unsurpassed views and sunsets. The whole group will enjoy easy access to supermarkets, restaurants, pharmacies, banks, transportation, paddle courts, etc. The Ventura mall is steps away from the apartment.

Top guest favorite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 31 reviews

Green Tower* 27th Floor Stunning views & Luxury

Truly the highest floor in the building, this modern luxury retreat soars above the city with breathtaking panoramic views. Sleek finishes, stylish decor, and plush comforts create a refined, high-end ambiance. Whether you’re sipping wine at sunset or waking up in the clouds, this stunning high-rise sanctuary delivers an unforgettable, elevated stay.

Popular amenities for Las Cruces vacation rentals

  1. Airbnb
  2. Bolivia
  3. Santa Cruz
  4. Las Cruces