Pet-friendly vacation rentals in Jefferson County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Jefferson County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Tiny home in Pacific

4.96 out of 5 average rating, 244 reviews

Route 66 Railroad Shanty, a cozy artsy small space

This 536 s.f. house, believed to have once been a sleeping shanty for railroad crews switching shifts for the night. Fully renovated and updated in 2021 by a local artist, you will find custom metal art throughout, granite countertops and a very warm cabin feel featuring a kitchen and bathroom finished with locally sourced Missouri dark red cedar, 10 minutes from six flags, Purina farms 15 min from hidden valley and 45 min from downtown this place is in a great location and will not disappoint!

Guest favorite

Home in Pacific

4.92 out of 5 average rating, 131 reviews

Pacific Palace, super unique!

The Pacific Palace is unlike any other Airbnb! Located in the heart of downtown Pacific, Missouri - only 2 minutes from Highway 44 and 10 minutes from Purina. This house is an incredible one of a kind treasure with lots of unique features including: outdoor gazebo, Koi pond, all original cedar interior design, two second story balconies, two large bat tubs (one located in the master bedroom) and so much more!!! Private parking and a gate for added privacy. Just minutes from Six Flags. Book today

Guest favorite

Cottage in Eureka

4.92 out of 5 average rating, 300 reviews

Beautiful Cottage on Large Private Lot

This lovely rural cottage is nestled back in the woods on its very own private acre of land. It offers guests a beautiful getaway experience while walking the property or hanging out on the large covered front porch; while at the same time being just a 7 minute drive from downtown Eureka with its many delicious restaurants and adorable boutiques. If Six Flags is your goal you can enjoy the hustle bustle of the amusement park during the day and relax after a 15 minute drive back to the cottage.

Superhost

Home in Pacific

4.87 out of 5 average rating, 61 reviews

'Lucky Dawg' Pet-Friendly Abode Near St Louis!

Come and hang out at 'Lucky Dawg,' a cozy house in the heart of Pacific, about 30 miles from amazing St. Louis attractions! Built in the 1940s, this fully-renovated, 2-bedroom, 1-bathroom vacation rental is the ideal escape for a small family or friend group. Bring your furry friends with you; they can play in the fenced yard while you roast marshmallows over the wood-burning fire pit! Explore nearby hiking trails, visit Purina Farms, or spend the day at Six Flags St. Louis, only 5 miles away!

Guest favorite

Cabin in Pacific

5 out of 5 average rating, 12 reviews

Charming cabin/outstanding view

Unique and tranquil getaway Charming cabin on almost 4 acres of 19 acre lake development. Relax on the deck enjoying the peace and quiet. Deer frequent the property and lake is stocked for fishing. Bedroom has bunks plus a twin bed and there is a full sized Murphy bed. Plenty of firewood for the firepit or the woodburning fireplace. Six Flags, Hidden Valley, Purina Farms, Shaw Nature Preserve are just a short drive. Enjoy hiking at 3 close by conservation areas & several state parks.

Guest favorite

Guesthouse in Barnhart

4.92 out of 5 average rating, 12 reviews

Summit View Guest House

Nestled away from the all the hustle and bustle yet conveniently close to everything. Here at Summit View is like your own little oasis 10 minutes from town. Our space is a rustic themed guesthouse retreat located above our detached garage overlooking the shared pool, patio and outdoor kitchen/ bbq area. In the early mornings and afternoons you may spot deer grazing in the backyard. Summit View is pet friendly! We have 2 small dogs Penny & Merle. Both are friendly and play together outside.

Guest favorite

Cabin in Dittmer

4.98 out of 5 average rating, 101 reviews

Lodge At Camp Skullbone In The Woods

Hot tub is not working The lodge is 3700sq ft. with 3 bedrooms and 2 baths. The Master bedroom has a queen-size bed and a large bathroom with a double shower and a clawfoot tub. Off the master bath, there is a Hot Tub. The game room has a pool table & poker table. Have a glass of wine or a nice cold beer and sit on the back deck around the firepit. The lodge will comfortably sleep about 14 people. Get up in the morning and grab a hot cup of coffee and watch the beautiful sunrise.

Guest favorite

Treehouse in Dittmer

4.81 out of 5 average rating, 132 reviews

The Den at Dittmer Hollow

Newly Updated** Enjoy the lovely setting of this romantic spot in nature, with a semi-primitive, modern cozy secluded treehouse in the woods! Explore 10 acres or wind down on the deck before relaxing in the *NEW* hot tub. The cabin inside has a very minimalistic design featuring on the first floor an electric fireplace, air conditioner, table, refrigerator, leather futon couch, kitchenette with a hand crank water pump sink, axe throwing and porta-potty bathroom.

Top guest favorite

Home in Pacific

4.92 out of 5 average rating, 97 reviews

Peaceful, home in Pacific, Just like Grandma's!

Full kitchen, washer/dryer, wifi, secluded setting just minutes to town. 7 mins to Six Flags 12 mins to Purina Farms 15 min to Hidden Valley Skiing 5 mins to I-44, 5 min. to River access 35 minutes to the downtown ST Louis, Arch, Busch Stadium, City Museum. 20 min. to Magic House, Science Center, Zoo. 25 mins. to Outlet Malls 10 minutes to St Alban Kid friendly! pets welcome-NOT on furniture or beds, please crate if gone. Additional pet fee applies.

Guest favorite

Cottage in Hillsboro

4.92 out of 5 average rating, 163 reviews

Shagbark Hickory Hot Tub & Sauna Retreat

Take it easy at this unique and tranquil getaway. Enjoy a detox in our handcrafted sauna, or take a soak in the hot tub under the stars! Full kitchen, bathR w/claw foot, & screened in porch. It’s very private, with land to explore. Take a stroll to the pond or creek or book a massage with our own licensed Massage therapist! Close to La Chance winery, Desoto town, Big River access points, valley view glades, & Washington state park.

Top guest favorite

Cottage in De Soto

4.97 out of 5 average rating, 111 reviews

Rock House Retreat

Unplug and enjoy a slower pace of life at this picturesque rock cottage. The 1920’s former hunting lodge was built from stone sourced from the property, and is as charming as ever. Enjoy an early morning stroll on one of the many hiking trails, or just relax on the porch while sipping coffee. There are many great hiking opportunities within a short drive, however, once you get settled in you may not find a reason to leave.

Guest favorite

Home in Barnhart

4.92 out of 5 average rating, 328 reviews

3 Bedroom Ranch with Deck in a Quiet Neighborhood

• Ranch style w/ 1025 square feet • Subdivision neighborhood w/ grassy common ground areas • Driveway parking for 2 vehicles • Safe neighborhood • 52" TV w/ Roku streaming stick • A baby gate at the top of the steps to the basement laundry room • Deck and backyard • Close to Hwy 55, about a 30 minute drive from Down Town St. Louis. • Near Historic Kimmswick (quaint shops & resturants), and Mastodon State Park

0 of 0 items showing

What guests are saying

Cozy town house - fenced backyard - Barnhart

4.87 out of 5 average rating, 68 reviews2 weeks ago

We enjoyed staying at this townhouse very much. It was cozy and very clean with all the appointments necessary to make our stay comfortable. The location was quiet both day and night. We had our own private parking space right outside the door. The owner did a wonderful job communicating with us. She is a pleasant friendly person, and she made us feel welcome. We would definitely stay at her location on future visits to the St. Louis/Arnold area.

Townhouse in Barnhart

What guests are saying

Hand Built Log Cabin

4.87 out of 5 average rating, 93 reviews5 days ago

This place is amazing! Christina was so kind. She had Easter eggs for the kids hid through the air b and b! She had bacon eggs and snacks for us, which was appreciated so much! We went geode hunting, pet and feed the horses and goats. The cabin was clean and so cool! Extra spacious, stocked with everything you need, tons of board games, lots of towels and the beds were comfy! We traveled a little distance to go to elephant state park and Johnston Shut in's, so while it's peaceful, it's a short drive to a lot of neat stuff. I feel greatful to be able to stay somewhere so amazing with my kiddos! They loved every minute of it!

Cabin in Bonne Terre

What guests are saying

Relaxing Log Cabin Getaway on 20 Acres

4.98 out of 5 average rating, 62 reviews4 days ago

This cabin never disappoints. The beds are super comfy, the kitchen is amazing and the whole house is so beautiful. It is very peaceful. We have had family reunions there every year for the past three years and now has become an annual tradition. It is just wonderful

Cabin in Festus

What guests are saying

Winery Adjacent RV on large farm

4.81 out of 5 average rating, 43 reviews12 months ago

We loved the tranquil environment and the quietness. It was the perfect location for us while we were in Missouri for the solar eclipse. Our 2 dogs had a huge field to run in and be active. We had everything we needed and were very comfortable. It was the perfect space for us and I highly recommend it!

Camper/RV in Catawissa

What guests are saying

Glamping in the Woods! W/ electric and heated

4.71 out of 5 average rating, 24 reviews6 months ago

This was last minute and a much needed get away. My spouse and I didn’t get off work until late, and got in just after midnight. Needed a break. Not only was it beautiful, peaceful & quiet, but everything needed was provided. The communication was spectacular. The grounds were beautiful and clean and there were friendly animals and people on the grounds. Gave us space but left room for hellos and kindness. Look forward to our next trip already! Def recommend!

Yurt in Blackwell

What guests are saying

Missouri Retreat w/ Deck, Grill & Shuffleboard!

4.89 out of 5 average rating, 9 reviews9 months ago

Located off historic Route 66, this craftsman home is a gem. The home is beautiful and spacious. The town of pacific is nice and the unit is walking distance to restaurants and a custard stand. Quick drive to six flags or a tour down to wine country. The host is responsive and courteous. We would stay here again.

Home in Pacific