Guesthouse vacation rentals in Frederick County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Frederick County guesthouse rentals

Family-friendly guest house rentals

Superhost
Guesthouse in Frederick
4.83 out of 5 average rating, 36 reviews

The Wander Inn

KristinaRating, 5 stars1 month ago
I stayed for a little over a month while waiting to close on my house and really enjoyed it. Rani left out fresh fruit and provided breakfast items that came in handy and saved me some money on eating out. I slept comfortably each night and the radiator in the bathroom is better than any space heater. When I was feeling a little down I’d pop out back and watch the horses and a cute pair of cardinals. The view is gorgeous. I also became friendly with sweet gray cat and their bouncy, adorable dogs. All this made it feel like being at home. Rani was kind, welcoming, and warm in every interaction. Some after work chats were such a good reprieve from the stress of the office. 10/10 place.
Top guest favorite
Guesthouse in Smithsburg
4.97 out of 5 average rating, 743 reviews

Jewel Vinsota Artist's Guesthouse

CassidyRating, 5 stars2 weeks ago
Our second stay here, and we'll definitely be coming back for more. The place has everything you could wish for-- art supplies, musical instruments, a well-stocked kitchen, grilling supplies, and an incredible sculpture garden. The hosts were so responsive and thoughtful. We felt welcomed and cared for throughout the entire experience.
Guest favorite
Guesthouse in Frederick
4.98 out of 5 average rating, 182 reviews

Romantic Getaway - Heated Spa Open Year Round

MelissaRating, 5 stars1 week ago
Beautiful home and a beautiful location. It was a relaxing environment with very accommodating host. Felt comfortable and would stay again.
Guest favorite
Guesthouse in Frederick
4.97 out of 5 average rating, 338 reviews

The Shady Bear Cabin

KatieRating, 5 stars3 weeks ago
We highly recommend staying at the Shady Bear Cabin! It's close to town but peaceful enough to feel like you're on a vacation. Gerry is a wonderful host - very friendly and helpful. The cabin had just enough of everything we needed for the weekend stay. If we ever need to rent near Frederick again, we will definitely be repeat customers! Special shoutout to Mr. Moo, the sweetest cat concierge <3
Guest favorite
Guesthouse in Middletown
4.94 out of 5 average rating, 291 reviews

Indulge, Fresh Flowers, Frederick County Haven

ElciraRating, 5 stars2 weeks ago
Incredible home away from home!!! It's hard to describe all the little things they have to make your stay pleasant and comfortable. They have everything that u can think off and some more, even a nail clipper, board games, laundry room with soap etc etc. We stayed only for a night, but loved every minute there!!!

Guest house rentals with a washer and dryer

Guest favorite
Guesthouse in Keymar
4.98 out of 5 average rating, 65 reviews

Historic country guesthouse, newly renovated.

RoyRating, 5 stars1 month ago
Enjoyed our stay, wish we had more time. It was very peaceful and relaxing. A good spot to travel to Frederick and Emmitsburg. Loved the ambiance when we checked in with music and snacks waiting for us for our visit!
Guest favorite
Guesthouse in Mount Airy
4.96 out of 5 average rating, 125 reviews

Treasured Hideaway on the Hill

DianeRating, 5 stars1 week ago
The bed is probably the most important thing for us when choosing a rental. The master bedroom bed was excellent. The second bedroom, not so much. But if you don’t have back issues, it’s ok. We are really bed snobs 🥺
Superhost
Guesthouse in Frederick
4.83 out of 5 average rating, 36 reviews

The Wander Inn

KristinaRating, 5 stars1 month ago
I stayed for a little over a month while waiting to close on my house and really enjoyed it. Rani left out fresh fruit and provided breakfast items that came in handy and saved me some money on eating out. I slept comfortably each night and the radiator in the bathroom is better than any space heater. When I was feeling a little down I’d pop out back and watch the horses and a cute pair of cardinals. The view is gorgeous. I also became friendly with sweet gray cat and their bouncy, adorable dogs. All this made it feel like being at home. Rani was kind, welcoming, and warm in every interaction. Some after work chats were such a good reprieve from the stress of the office. 10/10 place.
Guest favorite
Guesthouse in Lovettsville
4.96 out of 5 average rating, 226 reviews

Cottage Escape in Virginia Wine Country

ColeRating, 5 stars1 week ago
Best Airbnb service I’ve had in a long time! What a gem of a cottage. Located in such a serene area. The hosts were attentive and flexible and responded so fast. We enjoyed the stay and would definitely go back!
Top guest favorite
Guesthouse in Smithsburg
4.97 out of 5 average rating, 743 reviews

Jewel Vinsota Artist's Guesthouse

CassidyRating, 5 stars2 weeks ago
Our second stay here, and we'll definitely be coming back for more. The place has everything you could wish for-- art supplies, musical instruments, a well-stocked kitchen, grilling supplies, and an incredible sculpture garden. The hosts were so responsive and thoughtful. We felt welcomed and cared for throughout the entire experience.
Guest favorite
Guesthouse in Frederick
4.98 out of 5 average rating, 182 reviews

Romantic Getaway - Heated Spa Open Year Round

MelissaRating, 5 stars1 week ago
Beautiful home and a beautiful location. It was a relaxing environment with very accommodating host. Felt comfortable and would stay again.
Guesthouse in Fort Ritchie
New place to stay

Lieutenant's Lodge

PetraRating, 5 stars1 month ago
Joyce is an excellent host and fort Ritchie is an amazing place to stay. We’d love to come back!
Guesthouse in Fort Ritchie
New place to stay

Barrick's Bungalow

TamikoRating, 5 stars2 weeks ago
Space was great. Spacious and nicely modernized into a little house, within a historic building and former military base. Beautiful surroundings with a bar and grill and a breakfast and lunch restaurant in easy walking distance. Hoat communicated well and told us we could check in a little early which was great for having a little down time between soccer games.

Destinations to explore