
Vacation rentals in Defoe
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Defoe
Guests agree: these stays are highly rated for location, cleanliness, and more.
0 of 0 items showing
1 of 3 pages
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Defoe vacation rentals
Other great vacation rentals in Defoe
Guest favorite

Home in Crittenden
4.95 out of 5 average rating, 39 reviewsSerene Kentucky Lake Cabin with a Hot Tub!
MissicaRating, 5 stars4 weeks ago
3/25-3/29 2025 This was a birthday trip for a set of 10 year old twins and let me just say, our trip couldn’t have been better. From the moment we walked inside and saw the extra special touches that were waiting for the girls with the balloons and sweet message written on the fridge. The home felt very homey and clean. It was everything that was described. We spent our days at the Ark Encounter and Creation Museum (which we highly recommend doing both) and this beautiful home is right in between both places so it wasn’t a very far drive. After long days of walking, it was so nice to be able to come back and relax in the hot tub. There was also what we assumed to be the sweetest neighborhood cat that came to visit us each day, which the kids loved. Overall this was a wonderful trip that we all enjoyed very much. We didn’t have any problems or issues so we had no reason to contact the host (Julie) but there’s no doubt in my mind that if we did need to she would’ve responded promptly.
Top guest favorite

Home in Louisville
5 out of 5 average rating, 10 reviewsDerby House with Hot tub and King Bed
MattRating, 5 stars1 month ago
We really enjoyed our time here. It’s very convenient to all the Louisville attractions. Check and process was very easy and the house was very clean. There were great restaurants nearby. In a very friendly neighborhood. Johlandi was very responsive, she is an excellent host.
Top guest favorite

Home in Louisville
5 out of 5 average rating, 13 reviewsBourbon City Bungalow
RachelRating, 5 starstoday
We enjoyed our short stay at Daniel's! The house was nice, clean and inviting. Definitely would stay here again!
Guest favorite

Apartment in Louisville
4.83 out of 5 average rating, 126 reviewsHighlands Harmony House - Near Cherokee Park
PennyRating, 5 stars2 weeks ago
The house was very nice and clean in quite neighborhood. The bedding was very comfortable. It was more comfortable than staying at a hotel. And our hostess (Deanna) was very friendly and helpful.
Guest favorite

Farm stay in Simpsonville
4.91 out of 5 average rating, 64 reviewsSpacious Home with Beautiful Views
RitaRating, 5 stars1 month ago
We had a great time! Our first impression was "so pleased" & that describes our stay. Loved the peace & quiet, but we were so close to places we wanted to visit. Very clean. Plenty of seating. We had family over for a meal. Impressed with the amount & variety of spices, etc. that were provided. Having the use of the garage was a bonus. We did fine with Wi-Fi & TV streaming which for us was a miracle! It was a wonderful homecoming & we look forward to a return visit.
Guest favorite

Home in Jeffersonville
5 out of 5 average rating, 9 reviewsAmazing 2 units house mins to Louisville!
RobertRating, 5 stars1 week ago
Renee’s place was excellent. She was very communicative from the beginning, helpful in giving some recommendations. The place is easy to get to with a great location. It was very quiet. I was with 4 other parents for our kids volleyball tournament and I would definitely stay here again. Thank you Renee for the hospitality.
Guest favorite

Home in Madison
4.85 out of 5 average rating, 20 reviewsBeautiful Bungalow on Main
MeganRating, 5 stars1 month ago
So nice, I’ve stayed twice! This is my second time in the bungalow and my second great experience! The bungalow is such a relaxing stay. We will see you again!
Guest favorite

Home in Prospect
5 out of 5 average rating, 6 reviewsSuperHost ~ Modern Retreat Near Louisville!
Shavon MarieRating, 5 stars1 month ago
I stayed for week & home was very clean, spacious & looked exactly like the photos! I would highly recommend booking a stay here!
Destinations to explore
- Louisville Vacation rentals
- Cincinnati Vacation rentals
- Lexington Vacation rentals
- Bloomington Vacation rentals
- Red River Gorge Vacation rentals
- Williamstown Vacation rentals
- Nashville Vacation rentals
- Frankfort Vacation rentals
- Nashville Vacation rentals
- Gatlinburg Vacation rentals
- Chicago Vacation rentals
- Western North Carolina Vacation rentals
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Rupp Arena
- Ark Encounter
- Kentucky Horse Park
- Big Four Bridge
- Buffalo Trace Distillery
- Louisville Slugger Field
- Heritage Hill Golf Club
- Louisville Slugger Museum & Factory
- River Run Family Water Park
- Waterfront Park
- Hamon Haven Winery
- Kentucky Derby Museum
- Kentucky Kingdom & Hurricane Bay
- Old Fort Harrod State Park
- Angel's Envy Distillery
- Idle Hour Country Club
- Anderson Dean Community Park
- Big Spring Country Club
- Falls of the Ohio State Park
- Valhalla Golf Club
- Muhammad Ali Center
- Charlestown State Park
- Hurstbourne Country Club
- Frazier History Museum