Vacation rentals in Cambridge

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Cambridge

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A modern cabin is set on a landscaped lot with a gravel path leading to the entrance. The structure features a mix of dark siding and wood accents, surrounded by open fields and distant tree lines, offering a serene rural setting.
Cabin in Princeton
4.96 out of 5 average rating, 177 reviews

Private & Modern. Near river and wildlife refuge!

Experience the outdoors in comfort from this modern cabin, situated next to the 2200 acre Princeton Wildlife Management Area, and the nearby Mississippi River. It is ranked as the most “Wish Listed” Iowa listing of 2025 on Airbnb. Are you into hiking, biking, fishing, hunting, boating, or other water, winter, and summer activities? This cabin can support it all! Sit back and relax on the large deck while enjoying a coffee & the local wildlife, flora, & fauna of the Mississippi Valley Region.

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Top guest favorite
The exterior of the home features a tan façade with green shutters on the windows. A concrete pathway leads to the entrance, which includes a porch with steps. The surrounding area is beautifully landscaped with a grassy lawn and flower beds, offering a serene view of the neighborhood.
Home in Geneseo
4.99 out of 5 average rating, 108 reviews

Groovy 60s Themed House

Enjoy this completely remodeled home that’s a step back in time. Filled with 60s decor, style and flare with modern amenities and the comfort of home. Step into the lower level to shoot some pool or relax with tunes on the record player. A spacious deck overlooks a wooded area for a relaxing quiet night. The Airbnb house is owned by C&S Antique Mall - which is open daily for your shopping fix. Just minutes from historic downtown and close to restaurants and shopping, the location is perfect.

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Guest favorite
Cabin in Moline
4.93 out of 5 average rating, 245 reviews

River Views in Front Horses in Back-Kayaks & Bikes

Wake up to sweeping Rock River views in the front and peaceful views of horses grazing in the back. Sip your morning coffee on the wraparound deck, explore the nearby bike path on the two included bikes, paddle out in the kayaks, and end your evening by the firepit as the sunset glows across the water. This eclectic riverfront bungalow blends vibrant décor, cozy comfort, and easy indoor-outdoor living. It’s perfect for girls’ weekends, fishing trips, romantic escapes, or peaceful getaways.

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Guest favorite
A serene view of the river at sunset, reflecting soft hues in the calm water. A gazebo is visible nearby, alongside a swing set on lush grass. A fire pit stands ready for gatherings, and boats are docked in the background.
Home in Le Claire
4.89 out of 5 average rating, 107 reviews

Rivers Paradise

This home has fabulous views of the mighty Mississippi, with plenty of space to allow you to absorb the beautiful atmosphere and relax comfortably. There is plenty of parking space , and it also has its own boat launch and dock . Lots of room for entertainment indoors and out . Grill and relax on the deck or have your morning coffee in the gazebo by the river . There are also 3 garage spaces . Three large bedrooms with king size beds, and three full baths. Bunk bed as well

ValueFamilyGetting around

Top guest favorite
The exterior of a quaint single-story home features a welcoming porch with a wooden railing and an American flag. Lush greenery surrounds the entrance, complemented by decorative flower beds. A large, partially fenced backyard is visible, adding to the inviting charm of the property.
Home in Toulon
4.92 out of 5 average rating, 136 reviews

Laten Lodge

Experience Small-Town Living at Its Best… You’re just a short walk from the town park, local restaurants, bars, a charming ice cream shop, and a cozy coffee shop. Outdoor enthusiasts will appreciate the Rock Island Trail, which starts on the east side of town and stretches all the way to Peoria, Illinois—great for walking, running, or biking. Whether you’re here for a weekend escape or an extended stay, you’re sure to enjoy everything this small-town gem has to offer.

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Top guest favorite
A stately three-story house features a broad front porch with a symmetrical design. Lush green grass surrounds the property, complemented by neatly trimmed shrubs. The pathway leads to the inviting entrance, flanked by large windows on either side, enhancing the welcoming appearance of the home.
Home in Cambridge
4.97 out of 5 average rating, 37 reviews

The Cambridge House Hotel

The Cambridge House Hotel has been in active service as the the Cambridge Lutheran Church Parsonage for over 100 years.. and now you can stay in this magnificent House. Enjoy the front row seats to the Cambridge Lutheran Church Bell Carillon twice per day. Forget your worries in this spacious and serene space. Corporate rate is an additional $50/night. This property is strictly no-smoking/no-vaping.

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Guest favorite
The exterior of the bungalow showcases a wooden facade and green roof, surrounded by lush greenery. A deck is visible, enhancing outdoor living space. The river is seen in the background, framed by trees, contributing to the serene environment.
Cabin in Rock Island
4.88 out of 5 average rating, 419 reviews

Retro River Retreat

Gorgeous bungalow tucked away from city life on the Rock River. Enjoy year round river views from nearly every window in this comfy cabin. Dead end street offers privacy and seclusion. Right in town yet surprisingly tucked away. Good for extended stays, staycations, romantic get away or just passing through. Guests do not have access to river from this property.

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Top guest favorite
A cozy living area features a gray sectional sofa with decorative pillows. A flat-screen smart TV sits on a shelf illuminated in purple tones, displaying various streaming options. Natural light enters through the window, while a door leads outside, enhancing the welcoming atmosphere.
Home in Moline
4.92 out of 5 average rating, 219 reviews

The Little Gem

Kick back and relax in this calm, stylish space. We have 1 bedroom with a queen bed, smart TVs and USB charging lamps. Feel free to prepare a meal in our stocked kitchen or prepare yourself a cup of coffee. This location is right off the Avenue of the Cities and is near grocery stores, restaurants and gas stations.

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Top guest favorite
The historic building is framed by snow-covered branches, showcasing its classic architectural details. A prominent cupola with a red dome and green clock face is visible above the roofline. Snow blankets the structure and the surrounding landscape, creating a serene winter scene.
Home in Bishop Hill
4.98 out of 5 average rating, 295 reviews

Lilla Vita Guest House, Historic Bishop Hill

Explore historic Bishop Hill then get some rest and relaxation in our newly remodeled guest house. Ideal for 1-4 guests. Within walking distance to several quaint shops, museums and restaurants. In an effort to keep ourselves and everyone else healthy, we are currently booking only weekends with a 2-day minimum.

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Top guest favorite
Comfortable seating is provided by a light-colored armchair with wooden accents, positioned next to a small table. A potted plant adds greenery to the corner, while a lamp offers soft illumination. An artistic wall piece enhances the overall aesthetic of the cozy living area.
Apartment in Wyoming
4.97 out of 5 average rating, 143 reviews

Heaven on 7th.

Rear of building private access upstairs studio apartment, in the heart of a quaint little Wyoming, IL. Great location with outdoor deck. Located on the Rock Island Bike Trail. King bed. Plenty of towels, blankets, pillows. Washer and Dryer Walking distance to local churches and funeral home.

LocationFamilyQuiet

Top guest favorite
A single-story house is set on a grassy area, surrounded by trees and greenery. The exterior features light-colored siding and a small flight of steps leading to the entrance. A gravel pathway leads up to the home, complementing the natural landscape.
Tiny home in Cambridge
4.98 out of 5 average rating, 113 reviews

Tiny house big heart

This house may be small, but the outdoor lovers like me, will love it. This property is on over 1/2 an acre surrounded by trees and squirrels. Whether you are a front porch sitter or back patio sitter, we got you covered with both! I am offering a low price, so everyone can afford to get away.🧳

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Top guest favorite
The exterior of a charming bungalow is shown, featuring light gray siding and red trim. A welcoming sign labeled 'Walnut Grove Farm Guest House' is attached to the porch. In the background, a large red barn is visible, surrounded by green grass and trees.
Farm stay in Knoxville
4.87 out of 5 average rating, 142 reviews

Walnut Grove Farm Bed and Breakfast

The Walnut Grove Farm Bed and Breakfast is a turn-of-the-century bungalow that offers the authenticity of a 19th century farm with the comfort of modern-day living. Please note rate is based on 2 people ($120 per night), $30 per additional guests.

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Popular amenities for Cambridge vacation rentals