Guesthouse vacation rentals in Anderson County

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Popular amenities for Anderson County guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
The exterior of the property is shown, featuring yellow siding complemented by dark shutters on the windows. A single door with glass panels is visible, providing a welcoming entrance. A grassy area is located at the base of the wall, enhancing the outdoor setting.
Guesthouse in Liberty
4.93 out of 5 average rating, 197 reviews

Holly Hideaway! 10 Highway miles to Clemson U!

RittaRating, 5 stars1 month ago
Jen’s Hideaway is the perfect private spot to come back to after visiting Central and Clemson. It is extremely clean and well appointed. The bed is very comfortable. Jen is a friendly host. She even baked us delicious blueberry muffins.
Guest favorite
A spacious living area is presented with high ceilings. A neutral-toned sofa and an armchair are complemented by a coffee table at the center. Colorful artwork, including a world map, adorns the walls, contributing to a vibrant yet relaxing atmosphere.
Guesthouse in Pendleton
4.89 out of 5 average rating, 263 reviews

La Bella Farm

BryndenRating, 5 stars3 weeks ago
Had a lovely stay. Wonderful hosts, kept me informed and even answered all questions before they were asked. Was very peaceful, minimal noise day and night. A beautiful property and a very comfortable bnb. Would absolutely recommend staying here- especially for the price.
Guest favorite
A spacious private suite features a king bed with soft linens and decorative pillows. The dark accent wall adds depth, while a small kitchenette is visible in the background. Nightstands flank the bed, accompanied by soothing lighting. A plush area rug and bright decor contribute to a welcoming ambiance.
Private room in Pelzer
4.98 out of 5 average rating, 128 reviews

South Oaks Guesthouse

JadaRating, 5 stars1 month ago
Diane was so helpful and patient with us. We were looking for a private spot for my husband’s son’s wedding and it was absolutely perfect. The tree line driveway is just breathtaking, we love the area so much we have been talking about going back out. When we walked in the room we noticed fresh flowers in the room and bathroom. We loved the little touches that Diane added, as well as the butterscotch coffee cake. It truly is 10/10 I’ve never had anything like it I almost ate it all in one sitting 🤭. We’re not much for sweets so that was very enjoyable. Very thoughtful add. We’re very picking with our bedding, bed, and oh my goodness it gave us the sleep we needed after a long flight. Not too soft or firm. We were very happy about that. We enjoyed our stay, and are so grateful for Diane she has been amazing and super quick with responding to us. Made it really easy for us to check out. I ended up making an error on my end as far as the booking and she did great with helping us.
Top guest favorite
A comfortable living area is presented with a mix of seating options, including a couch and two armchairs. Natural light enters through the windows, which are dressed in soft curtains. A coffee table sits in the center, complemented by tasteful decor on the walls.
Guesthouse in Donalds
4.99 out of 5 average rating, 376 reviews

Home on the farm

SandraRating, 5 stars1 week ago
OMG I can not express enough the peacefulness and how wonderful this place is . Mrs. Ruth and Mr. Bob are so sweet . It was exactly what I was looking for. Sitting out on the screened porch with coffee in the morning you can hear the birds it was wonderful. The rental was very well kept and very clean . I will definitely want and will be going back. Thank you Mrs. Ruth & Mr. Bob for a wonderful time.
Guest favorite
A rustic cabin features a wooden exterior with a star decoration, surrounded by landscaped rocks and plants. A covered porch provides seating and is complemented by an umbrella. The structure is nestled among tall trees, creating a serene environment.
Guesthouse in Townville
4.86 out of 5 average rating, 256 reviews

Lisa’s Lodge

CameranRating, 5 stars2 weeks ago
Our friends that live down the street from this place were having a birthday get together. We stayed here for Memorial Day weekend and it was amazing! Very quiet and beautiful place. Wish we would have had more time to be able to use the pool. Will definitely be back when we come to visit the area.

Guest house rentals with a patio

Top guest favorite
A serene lake scene at sunset is depicted, showcasing vibrant hues of orange and pink reflecting on the calm water's surface. The silhouette of trees can be seen along the shore, enhancing the tranquil atmosphere.
Guesthouse in Seneca
5 out of 5 average rating, 35 reviews

One Particular Cove ... on Lake Hartwell

JohnRating, 5 stars1 month ago
We couldn’t be happier with our stay. Perfect size for the 4 of us. Ginny and Sid are wonderful hosts. Our flight was changed and delayed and we didn’t arrive till 3am and had to leave for Clemson graduation by 730am. With little to no time to sleep or eat breakfast they stocked the place with fresh pastries, fruit and bagels and cream cheese. We sadly were only to spend nights at the property so we did t get a chance to take the whole lake location in. I’d go back in a heartbeat
Top guest favorite
The guest house features a contemporary design with a white and gray exterior. A porch with seating is visible, complemented by hanging lights and an American flag. Lush green grass surrounds the house, enhancing the welcoming atmosphere of the property.
Guesthouse in Townville
5 out of 5 average rating, 25 reviews

Charming Waterfront Guest House

AshleyRating, 5 stars1 month ago
The stay at Beth’s place was amazing! They had anything you could need already there. We enjoyed the dock, floating raft and tubes that they put in the lake for us were a great touch. Our kids swam despite the cold temperatures. We would definitely stay again!
Top guest favorite
A living area features a large red couch accompanied by a matching armchair. A coffee table sits in the center, adorned with decorative items. Natural light enters through a nearby window, and a ceiling fan hangs overhead, adding to the comfort of the space.
Guesthouse in Clemson
5 out of 5 average rating, 44 reviews

Downtown Clemson Guest Suite!

ChristinaRating, 5 stars1 month ago
The studio was adorable! Great location, clean, new and perfect for our stay in Clemson. There were only two of us but, plenty of room. I only wish I had found it before graduation. I will definintely look to reserve again when we head down for games. Great communication from Casey!
Top guest favorite
A living area features a pair of comfortable leather sofas and a coffee table, with a decorative area rug beneath. In the background, a queen bed with a floral-patterned coverlet is positioned beside a wall adorned with artwork depicting guitars.
Guesthouse in Clemson
5 out of 5 average rating, 23 reviews

Adorable Cottage 2 mi. from Death Valley

AmyRating, 5 stars1 month ago
Clean, peaceful, great location to the campus. Hosts are friendly and kind. My second stay and I can’t wait to go back.
Top guest favorite
A stylish seating area features a pink armchair and a black tufted chair, accompanied by a small round side table. Above the chairs, a vibrant abstract art piece is displayed, incorporating bold strokes of black, gold, and white with a text element from Psalm 23:1.
Guesthouse in Honea Path
4.91 out of 5 average rating, 45 reviews

The Honey Flat

DeloresRating, 5 stars3 days ago
My husband and I stayed at Holly's place to attend the wedding of our granddaughter who was married in Honea Path and reception in Due West..the location was very good for all the activities involved. The house was perfect for us as it had everything we needed for our stay..We enjoyed the chickens, pigs and dogs on the property. Would definitely stay there again if the occasion arises. Delores and Reid Lowery..Shelby NC
Top guest favorite
A comfortable home featuring a light-colored exterior with a sloped roof. The front porch is accessible, and the driveway leads to a garage. A boat is parked beside the house, surrounded by green trees and a clear blue sky.
Guesthouse in Central
5 out of 5 average rating, 16 reviews

Vacation Home Clemson and Lakes

AnnRating, 5 stars1 month ago
We had a wonderful stay in this beautiful home for our Tiger's graduation from Clemson. The home was extremely clean and well stocked with everything we needed. We enjoyed the backyard and patio as well. The host was friendly and responsive.
Guest favorite
The exterior view of the Shou-Sugi-Ban Guest House features a dark wooden facade with a sloped roof. A spacious deck is present, furnished with two orange chairs and a potted plant. Lush greenery surrounds the area, providing a natural feel.
Guesthouse in Piedmont
4.99 out of 5 average rating, 95 reviews

Shou-Sugi-Ban Retreat on the Saluda River

ChristopherRating, 5 stars2 weeks ago
These are great hosts. We had a health/life/work challenge, and they were very flexible with us. This is no small thing and is not always the norm amongst hosts, and it deserves to be recognized. We didn't get to fully enjoy the place, so certainly read the reviews of others on that front, but we can attest to the hosts' character, ethics and values. They are good people of good fiber. And that's something in today's world...
Top guest favorite
The exterior features a two-story house with a welcoming porch. A path of laid brick leads through a well-kept lawn. The upper balcony is adorned with a canopy, and American flags are displayed. Lush greenery surrounds the home, creating a tranquil, inviting entrance.
Guesthouse in Seneca
5 out of 5 average rating, 17 reviews

Quin's Lake House, Keowee. Private bottom Floor.

EmmaRating, 5 stars2 months ago
This is a beautiful place to stay on the water. Owner is continuing to make updates to make the stay easier particularly in the kitchen area.

Guest house rentals with a washer and dryer

Guest favorite
A wooden front porch features a swing with patterned cushions and a decorative wreath on the door. Soft lighting fixtures are mounted above, and a natural area of grass and trees is visible beyond the porch, providing a peaceful outdoor setting.
Guesthouse in Pelzer
4.96 out of 5 average rating, 71 reviews

Quaint guest cottage in Upstate

DeborahRating, 5 stars2 days ago
Not our first stay at The Canning House and not our last! We love the country feel and the rain on the tin roof. It was so nice to wake up and see the cows out back in the pasture (took some pics there) and hearing the birds chirping. See you another time for sure!
Guest favorite
A modern kitchen area features light cabinetry and dark countertops. Stainless steel appliances, including a refrigerator and stove, are neatly arranged. A small dining table with two chairs is visible, and natural light filters through a window with blinds.
Guesthouse in Iva
4.92 out of 5 average rating, 13 reviews

Pine Trees Rest

KimRating, 5 stars10 months ago
Beautiful guesthouse! It was very clean and was exactly as pictured. Alexandra greeted us upon our arrival even though it was a little late. She is quick to respond to messages. I definitely recommend her home and will stay again when we are in that area.
Guest favorite
A charming back porch is displayed, featuring a small round table with rattan chairs. String lights are hung above, enhancing the natural light filtering through surrounding greenery. A potted plant adds a touch of greenery, making the space inviting for outdoor relaxation.
Guesthouse in Seneca
5 out of 5 average rating, 6 reviews

The Cottage at Keowee Hollow

CandaceRating, 5 stars1 month ago
We absolutely love The Cottage. It was close enough to my grandson’s graduation festivities in Clemson. It was so clean and private and we will definitely use it again on our next trip to the area.
A child sits on a wooden dock, holding a fishing pole while looking out over the calm lake. Two toy figures, resembling a cowboy and an astronaut, are positioned alongside. The serene water reflects the clear sky, surrounded by trees at a distance.
Guesthouse in Townville
5 out of 5 average rating, 9 reviews

Paradise Point on Lake Hartwell

ZachRating, 5 stars10 months ago
Paradise point was wonderful! Easy check-in, kids loved the game room, and the dock made it easy for kayaking & docking our boat. We will be back for sure!
Guest favorite
A clean and modern bathroom is featured, showcasing a white toilet and a shower area enclosed by a white curtain. A small potted plant is placed on a shelf above the toilet, while a woven basket filled with towels sits in the corner on a wood floor.
Guesthouse in Clemson
4.9 out of 5 average rating, 20 reviews

Clemson Carriage House - NEW!

TylerRating, 5 stars1 month ago
Ashley‘s carriage house was such a cute place to stay. It is very central in Clemson to everything you would need to go to and was perfect to attend an event in Clemson. Is extremely clean and I especially loved all the Clemson Tiger touches in decor. I would stay here again if I came back for a Clemson game!
The elevated rear of the house showcases multiple levels with spacious decks. Bright blue Adirondack chairs are arranged on a stone patio, complementing the natural landscape. Surrounding greenery and a gently sloped path lead to the home, enhancing the inviting outdoor space.
Guesthouse in Townville
4.67 out of 5 average rating, 6 reviews

Beautiful Luxury home on Lake Hartwell by Clemson

BradyRating, 5 stars34 months ago
Great place & location for peace and sound. Would highly recommend to stay there again.
Top guest favorite
A modern bathroom features a combination of gray tiled walls and a bathtub with a shower curtain. Above the toilet, framed images are displayed. A sink with a dark cabinet is positioned beside the toilet, while toiletries are neatly arranged on the counter.
Guesthouse in Clemson
5 out of 5 average rating, 22 reviews

Riggs Drive Gameday Getaway

SteveRating, 5 stars1 month ago
Really nice space walkable to downtown but on a quiet street. The space looks brand new, well designed and appointed. High ceiling ls and very open feel. Everything is high quality and very clean. We will definitely stay here when in the area

Destinations to explore