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Guesthouse vacation rentals in Alachua County

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Alachua County guesthouse rentals

Family-friendly guest house rentals

Superhost
Private room in Alachua
4.92 out of 5 average rating, 36 reviews

King room at Pareners Branch Creek Guesthouse

SonjaRating, 5 stars9 months ago
This place was a perfect getaway for us. The pool area is amazing and so relaxing. My family enjoyed the pickleball and basketball. The beds were so comfortable and the room was very clean. Jane greeted us and was very friendly and accommodating. We would love to visit again.
Guest favorite
Guesthouse in Gainesville
4.87 out of 5 average rating, 213 reviews

Sunflower Acres Cottage

SheenaRating, 5 stars2 weeks ago
This is our second time staying here, and we couldn’t be happier! This place has quickly become one of our favorites, and it tops our list whenever we're in the area. It has such a peaceful vibe and is always so clean. Plus, the interior is just lovely! We really enjoy our time here.
Guesthouse in Newberry
4.98 out of 5 average rating, 46 reviews

Gator Getaway

PaulRating, 5 stars23 months ago
A great, cozy place to stay. Its the closest place you will find right next to the Easton Archery Center.
Top guest favorite
Guesthouse in Gainesville
4.97 out of 5 average rating, 544 reviews

Renovated Private Studio - Walking Distance to UF

AngelaRating, 5 stars3 weeks ago
Came down for my son to attend Florida days. This place is absolutely perfect. The bathroom is amazing. This place has everything you need. Perfect little studio. Exactly as described and even better in person. This will be my go-to place when I visit my son!
Top guest favorite
Guesthouse in Gainesville
4.99 out of 5 average rating, 211 reviews

Beautiful Cottage 10 Minute Walk from UF & Stadium

EvaRating, 5 stars1 week ago
This was a fantastic rental. Quiet, private, very clean. Rich was helpful but not intrusive at all. I'm a light sleeper, but the thermostat and window treatments kept the place perfectly cool and dark, and the suite is super quiet. Thr selection of local beers in the fridge and coffee pods were a fantstic touch. Certainly the best airbnb experience I've ever had.
Top guest favorite
Guesthouse in Micanopy
4.93 out of 5 average rating, 168 reviews

Private bed and bath above detached garage.

EliseRating, 5 stars2 days ago
Wonderful, cute, very clean, very peaceful. As others have said, it's just a bit hard to locate, but it's well worth it. Be prepared for a bit of an adventure and you'll find a treasure worth seeking. :)

Guest house rentals with a patio

Top guest favorite
Guesthouse in Gainesville
4.97 out of 5 average rating, 79 reviews

Millhopper Modern near UF&Shands

CherylRating, 5 stars3 weeks ago
Kaloni’s place was adorable! There was attention to detail for anything you might need during your stay. The entire place looked like it was professionally decorated and I’m in love with the wallpaper in the bathroom! The location was convenient, the place sparkling clean and quiet! I highly recommend staying there.
Guesthouse in High Springs
4.71 out of 5 average rating, 21 reviews

Private Detached Pool House With Kitchenette

Diana JoRating, 5 stars1 month ago
We enjoyed our stay at Glenn's place. The room was private, clean and comfortable. It was located in a quiet neighborhood. We would recommend Glenn's if your looking for a nice place to stay that covers the basics.
Superhost
Guesthouse in Gainesville
4.83 out of 5 average rating, 46 reviews

The house of smiles.

JanisRating, 5 stars2 days ago
Great stay! Angela is very responsive and fixed and issue with the tv/internet. Thanks Angela!
Guest favorite
Guesthouse in Fort White
4.97 out of 5 average rating, 78 reviews

Horning’s Guest House -room for 14

IvyRating, 5 stars1 week ago
Stayed here for a day trip and this place was so nice!! The owners were so communicative and hospitable, even bringing us eggs, milk, and other condiments, The snow cone machine was so good, and we loved the variety of syrups for coffee! Everyone had a great time and there were more than enough spaces for people to sleep on. Will definitely have to book again😆
Top guest favorite
Guesthouse in Gainesville
4.96 out of 5 average rating, 227 reviews

Walk to UF! Historic King Bed Loft w/ Private Deck

PaulaRating, 5 stars2 weeks ago
We were comfortable in the space. Very convenient location to our points of interest. Would definitely book again.
Superhost
Guesthouse in Gainesville
4.65 out of 5 average rating, 20 reviews

Our Nest Cute House!

JingRating, 5 stars2 days ago
Luis is by far the best host I’ve encountered on Airbnb—kind, helpful, and incredibly responsive. The place was clean, cozy, and quiet, all at a great price. What more could you ask for? Highly recommended!!
Guest favorite
Guesthouse in Gainesville
4.88 out of 5 average rating, 33 reviews

Private entrance guest suite

RachelRating, 5 stars1 week ago
Had a wonderful stay!! The space is cozy and very convenient. Really quiet and perfect for me and my pup. Would definitely book another stay in the future.
Top guest favorite
Guesthouse in Gainesville
5 out of 5 average rating, 95 reviews

"Nest" in the Guest House up in the Trees near UF

KathleenRating, 5 stars1 week ago
We loved our stay in this beautifully appointed home. The kitchen was stocked with everything we needed to prepare a meal, and there were even snacks and drinks upon our arrival. Deborah goes above and beyond to make sure her guests feel welcome and well accommodated. We are so glad we found this very special place and will definitely return when visiting Gainesville again.

Guest house rentals with a washer and dryer

Guest favorite
Private room in Alachua
4.97 out of 5 average rating, 33 reviews

Cozy guest room w/double at Pareners Branch Creek

EsmeraldaRating, 5 stars1 month ago
Super sweet host, and room was incredibly cozy and I was able to feel right at home ear the beautiful Alachua scenery
Guest favorite
Guesthouse in Gainesville
4.9 out of 5 average rating, 223 reviews

Downtown Studio - 1/2 Mile from UF Campus

ZacharyRating, 5 stars1 month ago
Nice small guest house to stay in, right next to UF. Perfect for our needs.
Guest favorite
Guesthouse in High Springs
4.83 out of 5 average rating, 12 reviews

Mother in Law suite/Apartment @ Staycation

AntonioRating, 5 stars1 month ago
Another fantastic quick stay at this Airbnb in downtown High Springs! The location is unbeatable—just a short walk to great restaurants, shops, and coffee spots, and only a quick drive to the beautiful natural springs. The home was clean, comfortable, and had everything I needed for a relaxing stay. Whether you're here for outdoor adventures or just to enjoy the charming town, this is the perfect place to stay. I’ll definitely be back!
Guest favorite
Guesthouse in Gainesville
4.86 out of 5 average rating, 49 reviews

Cedar Guesthouse

AliRating, 5 stars1 month ago
It was a perfect location for visiting my children at the University of Florida. I had a great stay, I felt at home. The only thing was that there was no soap or shampoo, but fortunately I had brought my own. I would definitely stay there again.
Superhost
Guesthouse in Gainesville
5 out of 5 average rating, 3 reviews

Palm N' Pillow • Guesthouse by UF, HCA-FL & Shands

MikeRating, 5 stars1 week ago
We had a great short stay at the Palm-n Pillow! Gabriela was a great host! Hope to be back soon
Top guest favorite
Guesthouse in Gainesville
5 out of 5 average rating, 75 reviews

Garden Cottage Sanctuary

ShannonRating, 5 stars5 days ago
By far, the best place I have stayed in Gainesville. The home was lovely and very safe for someone traveling by themselves. Laura was a fantastic host by offering local suggestions and even had a welcome bottle of wine and snacks waiting on me. I will plan my work trips around availability as this is now the only place I want to stay.
Guest favorite
Guesthouse in Alachua
4.96 out of 5 average rating, 28 reviews

Sweetwater Studio, on 5 beautiful acres

CamillaRating, 5 stars3 months ago
Nice clean space for our quick weekend getaway. Bhishma provided clear instructions to help us arrive. We kept in touch letting him know we would be late arriving. He made sure the lights were on and the outside was nicely lit to provide Easy access to get in. Tidy and lovely space to relax, comfy beds made for a great night sleep. We drove through the small towns, enjoyed our time roaming through the quaint antique shops then to Gainesville for a little shopping and supper. Thanks Bhishma for a wonderful place to stay.
Top guest favorite
Guesthouse in Gainesville
4.97 out of 5 average rating, 35 reviews

2.1 miles to campus 1B/1BA Work desk 50”tv+streams

AngelaRating, 5 stars3 days ago
Mayra was the PERFECT host ! If I could give more than ⭐️⭐️⭐️⭐️⭐️ review I would! This place was the perfect fit if you are needing a peaceful, quiet, relaxing and most importantly private place THIS IS THE ONE ! Everything was exactly as stated and pictured and if I'm being honest the pictures does no justice. I book this place last minute and as soon as I booked Mayra was at my services exquisite customer service

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